Abstract:
A method of forming a polymeric composition comprising the steps of: contactinga monomeric mixture with a gelator to form a mixture; allowing the gelatorto self-assemble within the monomeric mixture to realise the gelating properties of the gelator; and initiating polymerisationof the mixture to form a polymeric composition having a network of gelators embedded therein; wherein the gelatorcomprises gelator components comprising two head groups linked by a spacer molecule, wherein the head groups compromise a multiplicity of hydrogen-bondable species to provide a multiplicity of hydrogen bonding interactions, and/or the head groups are selected so as to provide stabilising interactions such as pi-stacking. A polymeric composition comprising a network of gelator embedded therein is also provided.
Abstract:
Acrylate-terminated poly(beta-amino esters) are cross-linked to form materials useful in the medical as well as non-medical field. The polymeric starting material is combined with a free radical initiator, either a thermal initiator or a photoinitiator, and the mixture for cross-linking is heated or exposed to light depending on the initiator used. The resulting materials due to the hydrolysable ester bond in the polymer backbone are biodegradable under physiological conditions. These cross-linked materials are particular useful as drug delivery vehicles, tissue engineering scaffolds, and in fabricating microdevices. The materials may also be used as plastics, coating, adhesives, inks, etc. The cross-linked materials prepared exhibit a wide range of degradation times, mass loss profiles, and mechanical properties. Therefore, the properties of the material may be tuned for the desired use. The high-throughput approach to preparing a library of cross-linked poly(beta-amino esters) allows for the rapid screening and design of degradable polymers for a variety of applications.
Abstract:
The present invention relates to the development of a beaded high loading capacity polymer for solid phase synthesis and purification of solution-phase organic synthesis. The matrix comprises cross-linked polyethyleneimine units as in the formula (I), where ñ is a real number of 5-1500, and designates the average degree of polymerisation (dp) of polyethyleneimine, ã and õ are real numbers ranging from O to ñ. The high density primary and secondary amino functional groups on the resin function as the site for the excess reagents to react. In a particular aspect there is provided a cross-linked polymer matrix selected from the group consisting of a cross-linked polymer matrix formed from a macromonomer comprising a polyethyleneimine functionalized with at least one fragment comprising a vinyl group, wherein said fragment can be polymerized using radical or ionic initiators to form the cross-linked polymer matrix, or a cross-linked and beaded polymer matrix formed from a macromonomer comprising a polyethyleneimine and a polyfunctional alkyllating agent, under inverse suspension or inverse emulsion polymerisation conditions.
Abstract:
A soluble polyimide polymer with tethered oligomeric silsesquioxane compounds is produced using efficient, gentle reactions. A carboxylic acid attachment point on the polymer backbone is used to connect the oligomeric silsesquioxane. The oligomeric silsesquioxane compound includes an amine or an alcohol on an organic tether, which reacts with the carboxylic acid attachment point to produce either an amide or an ester bond. The amide or ester bond includes a carbonyl carbon directly connected to a phenyl group in the polymer backbone. The resultant polyimide polymer has many beneficial properties.
Abstract:
A hydrous soft contact lens whose surface exhibits a contact angle with water of 10 to 50 DEG when measured by the underwater bubble method and the angle of 30 to 90 DEG when measured by the droplet method in the air and which has a permeability coefficient for oxygen of 30 or more and a water content of 5 % or more. The hydrous soft contact lens preferably comprises a polymer prepared from a hydrophilic siloxanyl monomer represented by a specific general formula. The hydrous soft contact lens has a contact angle with water which is small and stable in water and in the air, is reduced in the adhesion of stains during use, has a high permeability coefficient for oxygen, is free from firm sticking thereof to a cornea, and can be worn for a long period of time.
Abstract:
The present invention relates to water or alcohol soluble or dispersible thermoplastic elastomeric copolymers and to cosmetic and pharmaceutical compositions containing these copolymers. This invention especially relates to copolymers useful for hair styling purposes, and the hair styling compositions containing these copolymers. This invention further relates to copolymers useful for providing cosmetic and pharmaceutical compositions for topical application to the skin. These topical skin care compositions are useful for delivering and/or transdermally transporting active ingredients to or through the skin.