公开(公告)号：WO2014020289A1

公开(公告)日：2014-02-06

申请号：PCT/FR2013/051875

申请日：2013-08-02

Applicant: VIT

Inventor： ROUX, Romain

IPC: G01N21/21 ,  G01R31/309 ,  G01N21/956

CPC classification number: G01N21/8851 ,  G01N21/21 ,  G01N21/9501 ,  G01N2021/1734 ,  G01N2021/1765 ,  G01N2021/95638

Abstract: L'invention concerne un procédé d'identification d'un matériau dans une scène, comprenant les étapes suivantes : éclairer la scène (1); réaliser au moins deux mesures simultanées de l'amplitude lumineuse de la scène pour des états de polarisation distincts de la lumière à l'aide d'au moins deux dispositifs de mesure positionnés selon des directions inclinées au-dessus de la normale de la scène; et en déduire une identification du matériau.

Abstract translation: 本发明涉及一种用于识别场景中材料的方法，包括以下步骤：点亮场景（1）; 使用位于场景正常以上的倾斜方向的两个测量装置，对光的单独极化状态进行场景的光振幅的至少两次同时测量; 并从中推断出材料的识别。

公开(公告)号：WO2013096590A1

公开(公告)日：2013-06-27

申请号：PCT/US2012/070884

申请日：2012-12-20

Applicant: RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK

Inventor： DANIAS, Ioannis ,  LIM, Hyungsik

IPC: G01N33/15 ,  G01N21/00 ,  A61F9/008

CPC classification number: G01N33/5044 ,  A61B3/10 ,  A61B5/4848 ,  G01J4/00 ,  G01J9/00 ,  G01J2009/002 ,  G01J2009/004 ,  G01N21/1717 ,  G01N21/21 ,  G01N21/63 ,  G01N21/636 ,  G01N33/4833 ,  G01N33/5008 ,  G01N2021/1734 ,  G02B21/002

Abstract: The subject matter disclosed herein pertains to a method for screening drugs using second-harmonic generation microscopy. The tissue is scanned with a pulsed laser light which has an excitation wavelength. At least some of microtubules within the tissue produce generated light with a second-harmonic wavelength that is half the excitation wavelength. A microtubule pattern within the tissue is determined based on an analysis of the generated second-harmonic wavelength.

Abstract translation: 本文公开的主题涉及使用二次谐波生成显微术来筛选药物的方法。 组织用具有激发波长的脉冲激光扫描。 组织内的至少一些微管产生产生的光，其二次谐波波长是激发波长的一半。 基于生成的二次谐波波长的分析来确定组织内的微管图案。

公开(公告)号：WO2009016169A2

公开(公告)日：2009-02-05

申请号：PCT/EP2008/059916

申请日：2008-07-29

Applicant: EADS Deutschland GmbH ,  GÖBEL, Johann ,  KESSLER, Matthias

Inventor： GÖBEL, Johann ,  KESSLER, Matthias

IPC: G01N21/03 ,  G01N21/33 ,  G01N21/53 ,  G01N21/64 ,  G01N27/64

CPC classification number: G01N21/53 ,  G01N15/0205 ,  G01N21/031 ,  G01N21/31 ,  G01N21/6486 ,  G01N24/084 ,  G01N33/0057 ,  G01N33/227 ,  G01N2021/1734 ,  G01N2021/392

Abstract: A device for the real-time analysis of airborne chemical, biological and explosive substances has at least a gas analysis sensor (4), a fluorescence/luminescence sensor (1) and a sensor (2) for determining the particle size and number of particles. Each of, the sensors is connected with to a multireflection cell (5) (multipass laser cell) as an open measurement path. In addition, and the device also includes an evaluation unit for the real-time analysis of chemical, biological and explosive substances.

Abstract translation: 用于实时分析空气化学，生物和爆炸物质的装置至少具有气体分析传感器（4），荧光/发光传感器（1）和传感器（2），用于确定颗粒尺寸和颗粒数量 。 每个传感器与作为开放测量路径的多反射单元（5）（多路径激光单元）连接。 此外，该设备还包括用于实时分析化学，生物和爆炸物质的评估单元。

公开(公告)号：WO1992021025A1

公开(公告)日：1992-11-26

申请号：PCT/GB1992000866

申请日：1992-05-14

Applicant: MEAT AND LIVESTOCK COMMISSION ,  CHADWICK, John, Philip ,  WARKUP, Christopher, Charles

Inventor： MEAT AND LIVESTOCK COMMISSION

IPC: G01N33/12

CPC classification number: G01N21/8507 ,  G01N21/33 ,  G01N21/474 ,  G01N21/80 ,  G01N33/12 ,  G01N2021/1734 ,  G01N2021/1782

Abstract: Meat quality sensing apparatus comprises a probe (2) for insertion into a meat carcass. The probe contains more than one meat characteristic sensor (15, 17, 18, 19). A distance measurement device (13) is provided for measuring the depth of insertion of the probe into the carcass.

Abstract translation: 肉质检测装置包括用于插入肉体的探针（2）。 探头包含多于一个肉类特征传感器（15,17,18,19）。 提供了一种距离测量装置（13），用于测量探头插入胎体的深度。

公开(公告)号：WO2018217466A2

公开(公告)日：2018-11-29

申请号：PCT/US2018/031886

申请日：2018-05-09

Applicant: APPLIED MATERIALS, INC.

Inventor： GOPALAN, Ramesh ,  CHO, Tom K. ,  ALAJAJIAN, Gevork ,  MARK, Michael J.

IPC: H01L21/67 ,  H01L21/66 ,  H05H1/46 ,  C23C16/44

CPC classification number: H01J37/32972 ,  G01N21/031 ,  G01N21/31 ,  G01N21/62 ,  G01N21/64 ,  G01N21/84 ,  G01N21/85 ,  G01N2021/1734 ,  G01N2021/8411 ,  H01L21/67063 ,  H01L22/10

Abstract: An apparatus includes a reactive species source, a spectral measurement volume, a light source to emit a light beam into the spectral measurement volume, a spectrometer to receive the light beam from the spectral measurement volume. The apparatus includes an a controller configured to, when a reactive species is present in the spectral measurement volume, control the light source to emit the light beam into the spectral measurement volume and the spectrometer to determine an environment spectrum using the light beam, and when the reactive species is not present in the spectral measurement volume, control the light source to emit the light beam into the spectral measurement volume and the spectrometer to determine a baseline spectrum using the light beam, calculate a net spectrum based on a difference between the environment spectrum and the baseline spectrum, and estimate a concentration of the reactive species based on the net spectrum.

公开(公告)号：WO2010127790A2

公开(公告)日：2010-11-11

申请号：PCT/EP2010/002587

申请日：2010-04-27

Applicant: BÜRKERT WERKE GMBH ,  MOLL, Georg ,  RABUS, Dominik ,  WINKLER, Michael

Inventor： MOLL, Georg ,  RABUS, Dominik ,  WINKLER, Michael

IPC: G01N21/05

CPC classification number: G01N21/05 ,  G01N21/53 ,  G01N21/532 ,  G01N21/534 ,  G01N2021/054 ,  G01N2021/1734 ,  G01N2021/1744 ,  G01N2201/0245

Abstract: Ein modulares optisches Sensorsystem für fluide Medien hat ein Messmodul, das eine austauschbare Fluidkammer und einen austauschbaren Optikhalter aufweist. Die Fluidkammer hat einen Eingang und einen Ausgang sowie einen Messraum für das fluide Medium. Der Optikhalter hat mindestens einen optischen Sender und mindestens einen optischen Empfänger. Dieser Optikhalter wird innerhalb des Messmoduls relativ zu der Fluidkammer in solcher Weise in Stellung eingesetzt, dass die von dem optischen Sender ausgehende Strahlung den Messraum für das fluide Medium in der Fluidkammer quert und auf den optischen Empfänger gelangt.

Abstract translation: 一种模块化光学传感器系统用于具有测量模块，其包括可更换的流体室和可互换透镜支架流体介质。 流体腔室具有输入端和输出端以及用于流体介质的测量室。 透镜夹持器具有至少一个光发射器和至少一个光接收器。 此透镜支架被插入相对的测量模块在所述流体室以这样的方式在寻找从光发射器发出的光束的辐射穿过在流体室中的流体介质中的测量室，并在光接收器到达内。

公开(公告)号：WO2004029673A8

公开(公告)日：2005-05-19

申请号：PCT/US0331036

申请日：2003-09-30

Applicant: UNIV TEXAS ,  CHANG SUNG K ,  MIRABAL YVETTE ,  FOLLEN MICHELE ,  MALPICA ANAIS ,  UTZINGER URS ,  STAERKEL GREGG ,  COX DENNIS ,  ATKINSON E NEELY ,  MACAULAY CALUM ,  RICHARDS-KORTUM REBECCA ,  BC CANCER AGENCY

Inventor： CHANG SUNG K ,  MIRABAL YVETTE ,  FOLLEN MICHELE ,  MALPICA ANAIS ,  UTZINGER URS ,  STAERKEL GREGG ,  COX DENNIS ,  ATKINSON E NEELY ,  MACAULAY CALUM ,  RICHARDS-KORTUM REBECCA

IPC: A61B5/00 ,  G01N21/47 ,  G01N21/64

CPC classification number: G01N21/6486 ,  A61B5/0071 ,  A61B5/0075 ,  A61B5/0084 ,  A61B5/4331 ,  G01N21/474 ,  G01N2021/1734 ,  G01N2021/174 ,  G01N2021/4745 ,  G01N2021/6419 ,  G01N2021/6423 ,  G01N2021/6484

Abstract: Systems and methods are described for improved diagnostic fluorescence and reflectance. A method of detecting tissue abnormality in a tissue sample in vivo detects a set of reflectance spectra emitted from a tissue sample as a result of illumination with an excitation light from a fiber optic probe that has at least one collection fiber positioned at a source-detector separation, and determining if the tissue sample is normal or abnormal based on the resulting reflectance spectra. Another method of detecting tissue abnormality in a tissue sample in vivo includes illuminating the tissue sample in vivo with at least one electromagnetic radiation wavelength selected to cause the tissue sample to produce a set of fluorescence intensity spectra indicative of tissue abnormality, detecting the resulting fluorescence intensity spectra, and determining if the tissue sample is normal or abnormal based on the resulting fluorescence intensity spectra. Yet another method of detecting tissue abnormality in a tissue sample in vivo includes combining the two methods described above.

Abstract translation: 描述了用于改善诊断荧光和反射率的系统和方法。 一种在体内检测组织样本中的组织异常的方法，检测由组织样本发射的一组反射光谱，该组由来自光纤探针的激发光照射而成，该光纤探针具有至少一个收集光纤位于源检测器 分离，并根据所得的反射光谱确定组织样本是正常还是异常。 在体内检测组织样本中的组织异常的另一种方法包括以选择的至少一个电磁辐射波长在体内照射组织样本，以使组织样品产生指示组织异常的一组荧光强度光谱，检测所得到的荧光强度 光谱，并且基于所得荧光强度光谱确定组织样品是正常还是异常。 在体内检测组织样本中的组织异常的另一种方法包括组合上述两种方法。

公开(公告)号：WO1991015867A1

公开(公告)日：1991-10-17

申请号：PCT/US1991002181

申请日：1991-03-28

Applicant: FIBERCHEM, INC.

Inventor： FIBERCHEM, INC. ,  KLAINER, Stanley, M. ,  FRANK, Chet, A. ,  DANDGE, Dileep, K. ,  GOSWAMI, Kisholoy

IPC: H01J05/16

CPC classification number: G01N21/7703 ,  G01N21/80 ,  G01N2021/0385 ,  G01N2021/1734 ,  G01N2021/1738 ,  G01N2021/174

Abstract: Single and multi-cell reservoir FOCS configurations, with single or dual fibers (6) with optional optical elements (12), have a cross-flow arrangement of the sample relative to the fiber. A wide variety of sensors, including pH, arsenic, benzene cyanide, hydrazine, cupric ion, TCE, mercuric ion, and iron (2+) are provided.

公开(公告)号：WO1989010550A1

公开(公告)日：1989-11-02

申请号：PCT/US1989001780

申请日：1989-04-27

Applicant: MICROPHORETIC SYSTEMS, INC.

Inventor： MICROPHORETIC SYSTEMS, INC. ,  BROWNLEE, Robert G.

IPC: G01N21/59

CPC classification number: G01N21/31 ,  G01J3/1838 ,  G01J3/2803 ,  G01J3/42 ,  G01J3/4406 ,  G01N21/274 ,  G01N21/64 ,  G01N27/44721 ,  G01N27/44756 ,  G01N2021/1734 ,  G01N2021/6417 ,  G01N2021/6491 ,  G01N2035/00306 ,  G01N2035/00316 ,  G01N2201/0446

Abstract: Automated capillary electrophoresis tests can be performed using the capillary electrophoresis instrument (99) of this invention. The capillary electrophoresis instrument (99) has means for automatically purging and replenishing electrolytes (101), for automatically entering a sample into the capillary tube (110) and for automatically performing capillary electrophoresis. A detector (104) for simultaneous detection of absorbance and fluorescence provides means for quantifying the species separated by electrophoresis.

公开(公告)号：WO2016192860A1

公开(公告)日：2016-12-08

申请号：PCT/EP2016/025053

申请日：2016-06-04

Applicant: RASCOPE AG

Inventor： SCHNEIDER, Urs

IPC: G01N21/64 ,  G01N21/65 ,  G01N21/94

CPC classification number: G01N21/65 ,  G01J3/0218 ,  G01J3/0272 ,  G01J3/06 ,  G01J3/44 ,  G01N21/6408 ,  G01N21/6456 ,  G01N21/6486 ,  G01N21/94 ,  G01N2021/1734 ,  G01N2021/1738 ,  G01N2021/8845

Abstract: The invention relates to an apparatus for analyzing a surface area of an object, comprising: a laser device (10) configured to emit monochromatic incident light (101) of a first wavelength (λ 1 ) as well as optionally a monochromatic incident light (102) of a second wavelength (λ 2 ) that differs from the first wavelength (λ 1 ), a first deflection means (20) configured to deflect said incident light (101, 102) onto a point (P ij (X i , y j )) of a surface area (A) of an object that is to be analyzed so that scattered light (104) is generated at said point (P ij (X i , y j )), wherein said deflection means (20) is further configured to deflect said incident light (101, 102) such that said surface area (A) is scanned in a pointwise fashion by said incident light (101, 102), a first sensor means (40) configured to detect said scattered light (104) and to provide from said detected scattered light (104) a scatter data set (S ij (λ k )) for the respective point (P ij (X i , y j )), wherein the respective scatter data set (S ij (λ k )) comprises intensities of the detected scattered light (104) for different wave numbers, and a processing unit (50) for processing and/or analyzing said data sets. Further, the invention relates to a method for analyzing a surface area of an object.

Abstract translation: 本发明涉及一种用于分析物体的表面积的装置，包括：激光装置（10），被配置为发射第一波长（λ1）的单色入射光（101）以及任选的单色入射光（102） 与第一波长（λ1）不同的第二波长（λ2）的第一偏转装置（20）被配置为将所述入射光（101,102）偏转到表面积的点（Pij（Xi，yj））上 （Pij（Xi，yj））产生散射光（104），其中所述偏转装置（20）进一步构造成使所述入射光（101， 102），使得所述表面区域（A）以所述入射光（101,102）的方式扫描，第一传感器装置（40）被配置为检测所述散射光（104）并从所述检测到的散射光 （104）对于各点（Pij（Xi，yj））的散射数据集（Sij（λk）），其中各个散射 数据集（Sij（λk））包括用于不同波数的检测的散射光（104）的强度，以及用于处理和/或分析所述数据集的处理单元（50）。 此外，本发明涉及一种用于分析物体的表面积的方法。