CARNOSIC ACID, CARNOSOL AND ROSMARINIC ACID ISOLATION METHOD

    公开(公告)号:WO2021038340A1

    公开(公告)日:2021-03-04

    申请号:PCT/IB2020/057159

    申请日:2020-07-29

    申请人: TÜBİTAK

    摘要: The invention relates to a method of separation by fractionalization of the antioxidant active ingredients of Rosemary plant, which are the diterpenes Carnosic acid and Camosol and the phenolic acid Rosmarinic Acid, through column chromatography method. The production process involves the passage of rosemary extract, which is obtained in/with a proper solvent, through a column packed with a suitable packing material, the separation of the part rich in carnosic acid and carnosol, and the obtainment of a deodorized product in powder form after drying. During the process, another extract containing rosmarinic acid with high antioxidant activity is also obtained. The invention thus allows the use of an extract rich in carnosic acid and carnosol and another extract containing rosmarinic acid -which are obtained at once with no need for additional processes like acidification, precipitation, membrane filtration or deodorization- in food, pharmaceutical and cosmetic sector applications.

    REMOVAL OF NUCLEIC ACIDS AND FRAGMENTS THEREOF FROM A BIOMASS MATERIAL

    公开(公告)号:WO2018115042A1

    公开(公告)日:2018-06-28

    申请号:PCT/EP2017/083683

    申请日:2017-12-20

    申请人: UNIBIO A/S

    摘要: The present invention relates to a method for providing a SCP product from a biomass material wherein said SCP product comprising a reduced amount of nucleic acids relative to the naturally occurring amount of nucleic acids in the biomass material, the method comprising the steps of: (i) providing the biomass material; (ii) subjecting the biomass material to a process of cell disruption, providing a disrupted biomass material; (iii) applying the disrupted biomass material to a first separation process resulting in a first retentate comprising proteins and/or cell debris, and a first permeate comprising nucleic acids; (iv) subjecting the first permeate to a second treatment separating the nucleic acids from vitamins, minerals and/or amino acids; (v) optionally, combining the first retentate obtained in step (iii) with the vitamins, minerals and/or amino acids obtained in step (iv), providing the SCP product comprising a reduced amount of nucleic acids relative to the naturally occurring amount of nucleic acids.

    SEPARATION MEDIUM
    5.
    发明申请
    SEPARATION MEDIUM 审中-公开
    分离介质

    公开(公告)号:WO2017103863A1

    公开(公告)日:2017-06-22

    申请号:PCT/IB2016/057694

    申请日:2016-12-16

    摘要: The invention relates to a separation medium for use in the separation of analytes from a feed stream containing suspended solids, processes of separation using the separation medium, and the use of the separation medium to separate analytes from a feed stream containing suspended solids. The separation medium is provided as a hydrogel having a structure whose surfaces are defined by a triply periodic minimal surface, the hydrogel comprising at least one ligand that binds at least one target analyte.

    摘要翻译: 本发明涉及用于从含有悬浮固体的进料流中分离分析物的分离介质,使用分离介质进行分离的方法以及使用分离介质将分析物与 含有悬浮固体的进料流。 分离介质作为具有其表面由三次周期性最小表面限定的结构的水凝胶提供,所述水凝胶包含至少一种结合至少一种目标分析物的配体。