CYCLIC PROCESS FOR THE PRODUCTION OF TAURINE FROM ETHYLENE OXIDE
    1.
    发明申请
    CYCLIC PROCESS FOR THE PRODUCTION OF TAURINE FROM ETHYLENE OXIDE 审中-公开
    从乙烯氧化物生产木质素的循环方法

    公开(公告)号:WO2015183343A1

    公开(公告)日:2015-12-03

    申请号:PCT/US2015/000061

    申请日:2015-05-20

    Applicant: HU, Songzhou

    Inventor: HU, Songzhou

    Abstract: The present invention discloses a cyclic process for the production of taurine from ethylene oxide in a high yield of greater than 95% by continuously converting the byproducts of the ammonolysis reaction, sodium ditaurinate and sodium tritaurinate, to sodium taurinate. The cyclic process is completed by using sulfur dioxide or sulfurous acid to neutralize sodium taurinates to recover taurine and to regenerate sodium bisulfite, which is then reacted with ethylene oxide.

    Abstract translation: 本发明公开了一种通过连续将氨解反应副产物,二月桂酸钠和三十三酸钠转化为牛磺酸钠的方法,以高产率高于95%从环氧乙烷生产牛磺酸的循环方法。 循环过程是通过使用二氧化硫或亚硫酸来中和牛磺酸钠来回收牛磺酸和再生亚硫酸氢钠,然后与环氧乙烷反应完成的。

    NOVEL INITIATOR FOR PREPARING ALKANESULFONIC ACIDS FROM ALKANE AND OLEUM
    2.
    发明申请
    NOVEL INITIATOR FOR PREPARING ALKANESULFONIC ACIDS FROM ALKANE AND OLEUM 审中-公开
    用于从烷烃和油中制备碱性酸的新型发酵剂

    公开(公告)号:WO2015071455A1

    公开(公告)日:2015-05-21

    申请号:PCT/EP2014/074747

    申请日:2014-11-17

    Abstract: A compound of the formula (I) ALK-SO 2 -O-O-SO 2 OX, wherein ALK is a branched or unbranched alkyl group, especially a methyl, ethyl, propyl, butyl, isopropyl, isobutyl group, or a higher alkyl group, and X = hydrogen, zinc, aluminium, an alkali or alkaline earth metal.

    Abstract translation: 式(I)的化合物,其中ALK是支链或非支链烷基,特别是甲基,乙基,丙基,丁基,异丙基,异丁基或高级烷基,X = 氢,锌,铝,碱金属或碱土金属。

    A METHOD OF MAKING A SYNTHETIC ALKYLARYL SULFONATE
    3.
    发明申请
    A METHOD OF MAKING A SYNTHETIC ALKYLARYL SULFONATE 审中-公开
    制备合成烷基磺酸酯的方法

    公开(公告)号:WO2009017497A3

    公开(公告)日:2009-09-17

    申请号:PCT/US2007074800

    申请日:2007-07-31

    CPC classification number: C07C303/14 C07C309/31

    Abstract: A process for preparing a synthetic petroleum sulfonate comprising (a) reacting a first amount of at least one aromatic compound with a first amount of a mixture of olefins having from about 8 to about 100 carbon atoms, in the presence of a strong acid catalyst; (b) reacting the product of (a) with an additional amount of at least one aromatic compound and an additional amount of strong acid catalyst and, optionally, with an additional amount of a mixture of olefins selected from olefins having from about 8 to about 100 carbon atoms, in the presence of a strong acid catalyst, wherein the resulting product comprises at least about 80 weight percent of a 1,2,4-trialkylsubstituted aromatic compound; (c) sulfonating the product of (b); and (c) neutralizing the product of (b) with an alkali or alkaline earth metal hydroxide or ammonia.

    Abstract translation: 一种制备合成石油磺酸盐的方法,包括(a)在强酸催化剂存在下,使第一量的至少一种芳族化合物与第一量的具有约8至约100个碳原子的烯烃混合物反应; (b)使(a)的产物与另外量的至少一种芳族化合物和另外量的强酸催化剂反应,并任选与另外量的烯烃混合物反应,所述烯烃混合物选自具有约8至约 在强酸催化剂存在下,其中所得产物包含至少约80重量%的1,2,4-三烷基取代的芳族化合物; (c)磺化(b)的产物; 和(c)用碱或碱土金属氢氧化物或氨中和(b)的产物。

    ANTIMICROBIAL MATERIALS AND PREPARATION THEREOF
    4.
    发明申请
    ANTIMICROBIAL MATERIALS AND PREPARATION THEREOF 审中-公开
    抗微生物材料及其制备

    公开(公告)号:WO2009072144A3

    公开(公告)日:2009-07-30

    申请号:PCT/IN2008000553

    申请日:2008-09-01

    Abstract: The invention relates to a monomelic antimicrobial agent, to a copolymer and polymer compositions having antimicrobial activity and to articles and products prepared from them. The invention also relate to methods for preparing the anti microbial copolymer and polymer compositions. The monomeric antimicrobial agent of the invention has the general formula (R)j-(SO3MM)m(L)n where j, l, m is an integer from 1 to 6, n is an integer from 0 to 6, M is a metal selected from Ag, Cu or Zn, L is a nitrogen, phosphorus or sulphur containing ligand selected from ammonia, an amine, pyridine, imidazole, pyrazole, triaryl phosphine, trialkyl phosphine, triaryl phosphate, trialkyl phosphate or a thiol, R is a linear or branched unsubstituted or substituted alkyl or alkenyl, an aryl or a substituted aryl carrying at least one reactive functional group.

    Abstract translation: 本发明涉及单体抗微生物剂,涉及具有抗微生物活性的共聚物和聚合物组合物,以及由其制备的制品和产品。 本发明还涉及制备抗微生物共聚物和聚合物组合物的方法。 本发明的单体抗微生物剂具有通式(R)j-(SO 3 MM)m(L)n其中j,l,m是1至6的整数,n是0至6的整数,M是 选自Ag,Cu或Zn的金属,L是选自氨,胺,吡啶,咪唑,吡唑,三芳基膦,三烷基膦,三芳基磷酸酯,三烷基磷酸酯或硫醇的含氮,磷或硫的配体,R是 直链或支链的未取代或取代的烷基或链烯基,带有至少一个反应性官能团的芳基或取代的芳基。

    ANTIMICROBIAL MATERIALS AND PREPARATION THEREOF

    公开(公告)号:WO2009072144A4

    公开(公告)日:2009-06-11

    申请号:PCT/IN2008/000553

    申请日:2008-09-01

    Abstract: The invention relates to a monomelic antimicrobial agent, to a copolymer and polymer compositions having antimicrobial activity and to articles and products prepared from them. The invention also relate to methods for preparing the anti microbial copolymer and polymer compositions. The monomeric antimicrobial agent of the invention has the general formula (R) j -(SO 3 MM) m (L) n where j, l , m is an integer from 1 to 6, n is an integer from 0 to 6, M is a metal selected from Ag, Cu or Zn, L is a nitrogen, phosphorus or sulphur containing ligand selected from ammonia, an amine, pyridine, imidazole, pyrazole, triaryl phosphine, trialkyl phosphine, triaryl phosphate, trialkyl phosphate or a thiol, R is a linear or branched unsubstituted or substituted alkyl or alkenyl, an aryl or a substituted aryl carrying at least one reactive functional group.

    ANTIMICROBIAL MATERIALS AND PREPARATION THEREOF
    6.
    发明申请
    ANTIMICROBIAL MATERIALS AND PREPARATION THEREOF 审中-公开
    抗微生物材料及其制备

    公开(公告)号:WO2009072144A2

    公开(公告)日:2009-06-11

    申请号:PCT/IN2008000553

    申请日:2008-09-01

    Abstract: The invention relates to a monomelic antimicrobial agent, to a copolymer and polymer compositions having antimicrobial activity and to articles and products prepared from them. The invention also relate to methods for preparing the anti microbial copolymer and polymer compositions. The monomeric antimicrobial agent of the invention has the general formula (R)j-(SO3MM)m(L)n where j, l, m is an integer from 1 to 6, n is an integer from 0 to 6, M is a metal selected from Ag, Cu or Zn, L is a nitrogen, phosphorus or sulphur containing ligand selected from ammonia, an amine, pyridine, imidazole, pyrazole, triaryl phosphine, trialkyl phosphine, triaryl phosphate, trialkyl phosphate or a thiol, R is a linear or branched unsubstituted or substituted alkyl or alkenyl, an aryl or a substituted aryl carrying at least one reactive functional group.

    Abstract translation: 本发明涉及一种单体抗微生物剂,一种具有抗微生物活性的共聚物和聚合物组合物以及由它们制备的制品和产品。 本发明还涉及制备抗微生物共聚物和聚合物组合物的方法。 本发明的单体抗微生物剂具有通式(R)j-(SO3MM)m(L)n,其中j,l,m为1至6的整数,n为0至6的整数,M为 选自Ag,Cu或Zn的金属,L是选自氨,胺,吡啶,咪唑,吡唑,三芳基膦,三烷基膦,磷酸三芳基酯,磷酸三烷基酯或硫醇中的氮,磷或硫的配体,R是 直链或支链的未取代或取代的烷基或烯基,芳基或带有至少一个反应性官能团的取代芳基。

    NEW COMPOUNDS AND THEIR USE IN MEDICINE, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
    8.
    发明申请
    NEW COMPOUNDS AND THEIR USE IN MEDICINE, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM 审中-公开
    新化合物及其在医药中的应用,其制备方法和含有它们的药物组合物

    公开(公告)号:WO2003048116A2

    公开(公告)日:2003-06-12

    申请号:PCT/IB2002/005064

    申请日:2002-12-02

    Abstract: The present invention relates to novel antidiabetic, hypolipidemic, antiobesity and hypocholesterolemic compounds of formula (I), their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them. More particularly, the present invention relates to compounds of the general formula (I) which are predominantly PPAR alpha agonists, their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them The present invention also relates to processes for the preparation of novel compounds of formula (I), novel intermediates, processes for their preparation, use of the novel intermediates in the preparation of the above said compounds and their use as antidiabetic, hypolipidemic, antiobesity and hypocholesterolemic compounds.

    Abstract translation: 本发明涉及式(I)的新型抗糖尿病,降血脂,抗胆固醇和低胆固醇血症化合物,其衍生物,其类似物,其互变异构形式,其立体异构体,其多晶型物,其药学上可接受的盐,其药学上可接受的溶剂合物和药学上可接受的组合物,其含有 他们。 更具体地说,本发明涉及通式(I)的化合物,其主要是PPARα激动剂,它们的衍生物,它们的类似物,它们的互变异构形式,它们的立体异构体,它们的多晶型物,其药学上可接受的盐,其药学上可接受的溶剂合物和药学上可接受的溶剂合物 含有它们的可接受的组合物本发明还涉及式(I)的新型化合物的制备方法,新型中间体,其制备方法,新型中间体在制备上述化合物中的用途及其作为抗糖尿病, 降血脂,抗肥胖和低胆固醇血症化合物。

    A MULTISTAGE PROCESS FOR THE PREPARATION OF HIGHLY PURE DEFEROXAMINE MESYLATE SALT
    9.
    发明申请
    A MULTISTAGE PROCESS FOR THE PREPARATION OF HIGHLY PURE DEFEROXAMINE MESYLATE SALT 审中-公开
    制备高纯度麦芽糖酸盐的多种方法

    公开(公告)号:WO01040164A1

    公开(公告)日:2001-06-07

    申请号:PCT/US2000/032574

    申请日:2000-11-30

    CPC classification number: C07C259/06

    Abstract: The present invention provides a purification process whereby deferoxamine B produced by a microorganism and in mixture with other polyhydroxamates produced by the microorganism may be converted into its mesylate salt substantially free of the other polyhydroxamates and substantially free of chloride ion. The process includes adsorption and desorption of the deferoxamine B on an adsorption resin, direct precipitation of the deferoxamine free base out of the eluent from the adsorption resin, contacting of the deferoxamine B free base with methanesulfonic acid and isolation of the deferoxamine B mesylate salt by precipitation. This process minimizes decomposition of deferoxamine B.

    Abstract translation: 本发明提供了一种纯化方法,其中由微生物产生的去铁胺B与由微生物产生的其它多羟基羟胺化合物混合可以转化为基本上不含其它多羟基异羟酸酯并基本上不含氯离子的甲磺酸盐。 该方法包括去铁胺B在吸附树脂上的吸附和解吸,从吸附树脂中将脱铁胺游离碱从洗脱液中直接沉淀出,脱铁胺B游离碱与甲磺酸接触,并通过以下步骤分离去铁胺B甲磺酸盐: 沉淀。 该方法使去铁胺B的分解最小化

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