发明授权
- 专利标题: 2-amino-1,3-propanediol compound and immunosuppressant
- 专利标题(中): 2-氨基-1,3-丙二醇化合物和免疫抑制剂
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申请号: US244942申请日: 1994-06-17
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公开(公告)号: US5604229A公开(公告)日: 1997-02-18
- 发明人: Tetsuro Fujita , Shigeo Sasaki , Masahiko Yoneta , Tadashi Mishina , Kunitomo Adachi , Kenji Chiba
- 申请人: Tetsuro Fujita , Shigeo Sasaki , Masahiko Yoneta , Tadashi Mishina , Kunitomo Adachi , Kenji Chiba
- 申请人地址: JPX Osaka JPX Tokyo
- 专利权人: Yoshitomi Pharmaceutical Industries, Ltd.,Taito Co., Ltd.
- 当前专利权人: Yoshitomi Pharmaceutical Industries, Ltd.,Taito Co., Ltd.
- 当前专利权人地址: JPX Osaka JPX Tokyo
- 优先权: JPX4-283281 19921021; JPX5-179427 19930720
- 主分类号: A01N33/02
- IPC分类号: A01N33/02 ; A01N43/40 ; A01N43/60 ; A01N57/00 ; C07C215/10 ; C07C215/18 ; C07C215/20 ; C07C215/24 ; C07C215/26 ; C07C215/28 ; C07C215/34 ; C07C215/42 ; C07C215/54 ; C07C215/56 ; C07C215/68 ; C07C217/28 ; C07C217/30 ; C07C217/34 ; C07C217/48 ; C07C217/52 ; C07C217/64 ; C07C217/72 ; C07C217/76 ; C07C219/06 ; C07C219/24 ; C07C219/30 ; C07C225/04 ; C07C225/06 ; C07C225/10 ; C07C225/14 ; C07C225/16 ; C07C229/22 ; C07C229/38 ; C07C229/46 ; C07C233/18 ; C07C233/31 ; C07C233/35 ; C07C233/36 ; C07C233/41 ; C07C233/43 ; C07C233/47 ; C07C237/06 ; C07C237/24 ; C07C237/30 ; C07C251/38 ; C07C271/20 ; C07C271/24 ; C07C271/28 ; C07C323/25 ; C07C323/30 ; C07C323/32 ; C07C323/34 ; C07C323/41 ; C07D207/06 ; C07D207/09 ; C07D207/32 ; C07D207/325 ; C07D207/335 ; C07D211/14 ; C07D211/26 ; C07D213/38 ; C07D213/40 ; C07D233/54 ; C07D237/08 ; C07D239/26 ; C07D241/12 ; C07D261/08 ; C07D263/32 ; C07D265/30 ; C07D275/02 ; C07D277/28 ; C07D279/12 ; C07D295/13 ; C07D295/135 ; C07D307/52 ; C07D309/32 ; C07D317/28 ; C07D333/20 ; C07D521/00 ; C07C211/00
摘要:
2-Amino-1,3-propanediol compounds of the formula (I) ##STR1## wherein R is an optionally substituted straight- or branched carbon chain, an optionally substituted aryl, an optionally substituted cycloalkyl or the like, and R.sup.2, R.sup.3, R.sup.4 and R.sup.5 are the same or different and each is a hydrogen, an alkyl, an aralkyl, an acyl or an alkoxycarbonyl, pharmaceutically acceptable salts thereof and immunosuppressants comprising these compounds as active ingredients.The 2-amino-1,3-propanediol compounds of the present invention show immunosuppressive action and are useful for suppressing rejection in organ or bone marrow tranplantation, prevention and treatment of autoimmune diseases or as reagents for use in medicinal and pharmaceutical fields.
公开/授权文献
- US5060823A Sterile transfer system 公开/授权日:1991-10-29