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公开(公告)号:EP1356032A2
公开(公告)日:2003-10-29
申请号:EP01955908.7
申请日:2001-07-20
发明人: YUE, Henry , KHAN, Farrah, A. , GURURAJAN, Rajagopal , HAFALIA, April, J., A. , CHAWLA, Narinder K. , ARVIZU, Chandra S. , RAMKUMAR, Jayalaxmi , GANDHI, Ameena, R. , POLICKY, Jennifer, L. , BAUGHN, Mariah, R. , TRIBOULEY, Catherine, M. , BANDMAN, Olga , NGUYEN, Danniel, B. , LU, Yan , BURFORD, Neil , LAL, Preeti , DING, Li , YAO, Monique, G. , ELLIOTT, Vicki, S. , RECIPON, Shirley, A. , KEARNEY, Liam , LU, Dyung, Aina, M. , GREENWALD, Sara, R. , TANG, Y., Tom , XU, Yuming , WALSH, Roderick, T. , GIETZEN, Kimberly, J. , YANG, Junming , JACKSON, Jennifer, L. , THORNTON, Michael
CPC分类号: C12N9/1205
摘要: The invention provides human human kinases (PKIN) and polynucleotides which identify and encode PKIN. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associatedd withd abberant expression of PKIN.
摘要翻译: 本发明提供了鉴定和编码PKIN的人类人类激酶(PKIN)和多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供了用于诊断,治疗或预防与PKIN异常表达相关的疾病的方法。
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公开(公告)号:EP1519741A2
公开(公告)日:2005-04-06
申请号:EP02791393.8
申请日:2002-12-04
发明人: GRIFFIN, Jennifer, A. , RAMKUMAR, Jayalaxmi , EMERLING, Brooke, M. , KABLE, Amy, E. , ELLIOTT, Vicki, S. , MARQUIS, Joseph, P. , BAUGHN, Mariah, R. , GORVAD, Ann, E. , YUE, Henry , LEE, Ernestine, A. , BECHA, Shanya, D. , TANG, Y., Tom , TRAN, Uyen, K. , SWARNAKAR, Anita , LEE, Sally , ISON, Craig, H. , HAFALIA, April, J., A. , TRAN, Bao , SPRAGUE, William, W. , KHARE, Reena , GANDHI, Ameena, R.
IPC分类号: A61K38/00 , A61K39/395 , C12Q1/00 , C12Q1/68 , G01N33/53 , C07K7/00 , C07K17/00 , C07K16/00 , C07H21/04
CPC分类号: C07K14/47
摘要: Various embodiments of the invention provide human proteins associated with cell growth, differentiation, and death (CGDD) and polynucleotides which identify and encode CGDD. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of CGDD.
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公开(公告)号:EP1485474A2
公开(公告)日:2004-12-15
申请号:EP02795774.5
申请日:2002-12-06
发明人: KABLE, Amy, E. , CHIEN, David , WILSON, Amy, D. , SWARNAKAR, Anita , GORVAD, Ann, E. , HAFALIA, April, J., A. , EMERLING, Brooke, M. , RAMKUMAR, Jayalaxmi , JIN, Pei , GRIFFIN, Jennifer, A. , MARQUIS, Joseph, P. , BAUGHN, Mariah, R. , CHAWLA, Narinder, K. , LEHR-MASON, Patricia, M. , KHARE, Reena , LEE, Sally , HAWKINS, Phillip, R. , BECHA, Shanya, D. , LEE, Soo, Yeun , ZEBARJADIAN, Yeganeh
CPC分类号: C12N9/1205 , C12N9/16
摘要: Various embodiments of the invention provide human kinases and phosphatases (KPP) and polynucleotides which identify and encode KPP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of KPP.
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公开(公告)号:EP1481081A2
公开(公告)日:2004-12-01
申请号:EP02736944.6
申请日:2002-05-17
发明人: TANG, Y., Tom , YUE, Henry , AZIMZAI, Yalda , BAUGHN, Mariah, R. , BURFORD, Neil , REDDY, Roopa , WALIA, Narinder, K. , DAS, Debopriya , NGUYEN, Danniel, B. , YAO, Monique, G. , ARVIZU, Chandra, S. , LU, Yan , GANDHI, Ameena, R. , GRIFFIN, Jennifer, A. , ELLIOTT, Vicki, S. , RAMKUMAR, Jayalaxmi , LAL, Preeti, G. , LU, Dyung Aina, M. , LEE, Ernestine, A. , LEE, Soo Yeun , YUE, Huibin , YANG, Junming , TRIBOULEY, Catherine M. , KABLE, Amy E. , SWARNAKAR, Anita
CPC分类号: C07K14/4702 , A61K38/00 , C12N9/20
摘要: The invention provides human lipid-associated molecules (LIPAM) and polynucleotides which identify and encode LIPAM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of LIPAM.
摘要翻译: 本发明提供了鉴定和编码LIPAM的人类脂质相关分子(LIPAM)和多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供了用于诊断,治疗或预防与LIPAM异常表达相关的病症的方法。
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公开(公告)号:EP1429806A2
公开(公告)日:2004-06-23
申请号:EP02761511.1
申请日:2002-08-22
发明人: DUGGAN, Brendan, M. , LEE, Sally , BAUGHN, Mariah, R. , HAFALIA, April, J.A. , CHAWLA, Narinder, K. , ELLIOTT, Vicki, S. , LEE, Soo, Yeun , KHARE, Reena , WILSON, Amy, D. , JIN, Pei , HAWKINS, Phillip, R. , TANG, Y., Tom , BURFORD, Neil , DING, Li , YAO, Monique, G. , BECHA, Shanya, D. , TRAN, Uyen, K. , CHIEN, David , ZEBARJADIAN, Yeganeh , RICHARDSON, Thomas W. , KABLE, Amy E. , CHANG, Hsin-Ru , SWARNAKAR, Anita , LEHR-MASON, Patricia M. , RAMKUMAR, Jayalaxmi
CPC分类号: C07K14/47
摘要: Various embodiments of the invention provide human extracellular messengers (EXMES) and polynucleotides which identify and encode EXMES. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of EXMES.
摘要翻译: 本发明的各种实施方案提供了鉴定和编码EXMES的人细胞外信使(EXMES)和多核苷酸。 本发明的实施方案还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 其他实施方案提供了用于诊断,治疗或预防与EXMES的异常表达相关的病症的方法。
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公开(公告)号:EP1409677A2
公开(公告)日:2004-04-21
申请号:EP02709076.0
申请日:2002-01-16
发明人: LEE, Ernestine, A. , CHAWLA, Narinder, K. , BAUGHN, Mariah, R. , AZIMZAI, Yalda , TANG, Y., Tom , YUE, Henry , THANGAVELU, Kavitha , XU, Yuming , ARVIZU, Chandra , WARREN, Bridget, A. , YAO, Monique, G. , AU-YOUNG, Janice , HAFALIA, April, J., A. , ELLIOTT, Vicki, S. , KALLICK, Deborah, A. , GANDHI, Ameena, R. , RICHARDSON, Thomas, W. , KHAN, Farrah, A. , LU, Yan , SWARNAKAR, Anita , RAMKUMAR, Jayalaxmi , NGUYEN, Danniel B. , GRAUL, Richard C. , LU, Dyung Aina M.
IPC分类号: C12N15/12 , C07K14/705 , C12N5/10 , A01K67/027 , C07K16/28 , C12Q1/68 , A61K38/17 , G01N33/68 , A61K39/395
CPC分类号: C07K14/705 , A61K38/00
摘要: The invention provides human receptors and membrane-associated proteins (REMAP) and polynucleotides which identify and encode REMAP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of REMAP.
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公开(公告)号:EP1409550A1
公开(公告)日:2004-04-21
申请号:EP02739996.3
申请日:2002-06-26
发明人: DELEGEANE, Angelo, M. , BOROWSKY, Mark, L. , KHAN, Farrah, A. , KEARNEY, Liam , RAMKUMAR, Jayalaxmi , CHAWLA, Narinder, K. , LU, Yan , HONCHELL, Cynthia, D. , KALLICK, Deborah, A. , EMERLING, Brooke, M. , GORVAD, Ann, E. , GRIFFIN, Jennifer, A. , WARREN, Bridget, A. , YUE, Henry , THANGAVELU, Kavitha , SPRAGUE, William, W. , ISON, Craig, H. , ELLIOTT, Vicki, S. , MASON, Patricia, M. , RICHARDSON, Thomas W. , TRAN, Uyen K. , SWARNAKAR, Anita , JIN, Pei , KABLE, Amy E.
IPC分类号: C07K17/00
摘要: Various embodiments of the invention provide human extracellular messengers (EXMES) and polynucleotides which identify and encode EXMES. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of EXMES.
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公开(公告)号:EP1390391A1
公开(公告)日:2004-02-25
申请号:EP02731927.6
申请日:2002-05-24
发明人: RAUMANN, Brigitte, E. , GRIFFIN, Jennifer, A. , HAFALIA, April, J.A. , BATRA, Sajeev , YAO, Monique, G. , FORSYTHE, Ian, J. , RAMKUMAR, Jayalaxmi , DUGGAN, Brendan, M. , BAUGHN, Mariah, R. , AZIMZAI, Yalda , WARREN, Bridget, A. , LAL, Preeti, G. , GIETZEN, Kimberly, J. , CHAWLA, Narinder K. , BECHA, Shanya, D. , TANG, Y., Tom , YUE, Henry , CHINN, Anna, M.
CPC分类号: C07K14/705 , A61K38/00 , A61K2039/505
摘要: The invention provides human transporters and ion channels (TRICH) and polynucleotides which identify and encode TRICH. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of TRICH.
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公开(公告)号:EP1385977A2
公开(公告)日:2004-02-04
申请号:EP02721790.0
申请日:2002-04-19
发明人: KLAMMER, Aaron, A. , HAFALIA, April, J., A. , DUGGAN, Brendan, M. , WARREN, Bridget, A. , EMERLING, Brooke, M. , TRIBOULEY, Catherine, M. , ARVIZU, Chandra, S. , HONCHELL, Cynthia, D. , NGUYEN, Danniel, B. , KALLICK, Deborah, A. , YUE, Henry , AU-YOUNG, Janice, K. , RAMKUMAR, Jayalaxmi , LI, Joana, X. , THANGAVELU, Kavitha , GIETZEN, Kimberly, J. , DING, Li , BAUGHN, Mariah, R. , YAO, Monique, G. , CHAWLA, Narinder K. , MASON, Patricia M. , LAL, Preeti G. , GRAUL, Richard C. , REDDY, Roopa , BECHA, Shanya D. , KAREHT, Stephanie K. , RICHARDSON, Thomas W. , TRAN, Uyen K. , ELLIOTT, Vicki S. , TANG, Y. Tom , AZIMZAI, Yalda , LU, Yan , XU, Yuming , KARETH, Stephanie K.
CPC分类号: C07K14/47 , A01K2217/05 , A61K38/00
摘要: The invention provides human secreted proteins (SECP) and polynucleotides which identify and encode SECP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of SECP.
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公开(公告)号:EP1320548A2
公开(公告)日:2003-06-25
申请号:EP01939490.7
申请日:2001-05-25
发明人: THORNTON, Michael , CHAWLA, Narinder, K , YUE, Henry , NGUYEN, Danniel, B , LAI, Preeti , GANDHI, Ameena, R , TRIBOULEY, Catherine, M , YAO, Monique, G , RAMKUMAR, Jayalaxmi , AU-YOUNG, Janice , LU, Yan , TANG, Y., Tom , AZIMZAI, Yalda , BRUNS, Christopher M., , GRIFFIN, Jennifer, A , YANG, Junming , SANJANWALA, Madhu, S , RAUMANN, Brigitte, E , LEE, Ernestine, A , HAFALIA, April , BAUGHN, Mariah, R , GREEN, Barrie, D , KHAN, Farrah, A , KEARNEY, Liam , ELLIOT, Vicki, S , SEILHAMER, Jeffrey, J , POLICKY, Jennifer, L , BOROWSKY, Mark, L , BURFORD, Neil , DING, Li , LU, Dyung, Aina, M , JACKSON, Jennifer, L
IPC分类号: C07K14/705
CPC分类号: C07K14/47
摘要: The invention provides human transporters and ion channels (TRICH) and polynucleotides which identify and encode TRICH. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of TRICH.
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