-
公开(公告)号：EP1385870B1
公开(公告)日：2010-03-17
申请号：EP01954764.5
申请日：2001-07-19
发明人： SAKSENA, Anil, K. , GIRIJAVALLABHAN, Viyyoor, Moopil , LOVEY, Raymond, G. , JAO, Edwin, E. , BENNETT, Frank , MC CORMICK, Jinping, L. , WANG, Haiyan , PIKE, Russell, E. , BOGEN, Stephane, L. , CHAN, Tin-Yau , LIU, Yi-Tsung , ZHU, Zhaoning , NJOROGE, F., George , ARASAPPAN, Ashok , PAREKH, Tejal, N. , GANGULY, Ashit, K. , CHEN, Kevin, X. , VENKATRAMAN, Srikanth , VACCARO, Henry, A. , PINTO, Patrick A. , SANTHANAM, Bama , WU, Wanli , HENDRATA, Siska , HUANG, Yuhua , KEMP, Scott Jeffrey , LEVY, Odile Esther , LIM-WILBY, Marguerita , TAMURA, Susan Y.
IPC分类号： C07K1/00
CPC分类号： C07K5/0202 , A61K38/00 , C07K5/0812 , C07K5/0827 , C07K7/02
摘要： The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.
-
2.发明公开
公开(公告)号：EP1481000A2
公开(公告)日：2004-12-01
申请号：EP03731956.3
申请日：2003-01-16
发明人： SAKSENA, Anil, K. , GIRIJAVALLABHN, Viyyoor, M. , LOVEY, Raymond, G. , JAO, Edwin , BENNETT, Frank , MC CORMICK, Jinping, L. , WANG, Haiyan , PIKE, Russell, E. , BOGEN, Stephane, L. , CHAN, Tin-Yau , LIU, Yi-Tsung , ZHU, Zhaoning , NJOROGE, George, F. , ARASAPPAN, Ashok , PAREKH, Tejal , GANGULY, Ashit, K. , CHEN, Kevin, X. , VENKATRAMAN, Srikanth , VACCARO, Henry, A. , PINTO, Patrick A. , SANTHANAM, Bama , KEMP, Scott Jeffrey , LEVY, Odile Esther , LIM-WILBY, Marguerita , TAMURA, Susan Y. , WU, Wanli , HENDRATA, Siska , HUANG, Yuhua , WONG, Jesse K. , NAIR, Latha G.
CPC分类号： C07K5/0804 , A61K38/00 , C07K5/0202 , C07K5/0812 , C07K5/0827 , C07K7/02
摘要： The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.
-
3.发明授权
公开(公告)号：EP1481000B1
公开(公告)日：2010-06-02
申请号：EP03731956.3
申请日：2003-01-16
发明人： SAKSENA, Anil, K. , GIRIJAVALLABHN, Viyyoor, M. , LOVEY, Raymond, G. , JAO, Edwin , BENNETT, Frank , MC CORMICK, Jinping, L. , WANG, Haiyan , PIKE, Russell, E. , BOGEN, Stephane, L. , CHAN, Tin-Yau , LIU, Yi-Tsung , ZHU, Zhaoning , NJOROGE, George, F. , ARASAPPAN, Ashok , PAREKH, Tejal , GANGULY, Ashit, K. , CHEN, Kevin, X. , VENKATRAMAN, Srikanth , VACCARO, Henry, A. , PINTO, Patrick A. , SANTHANAM, Bama , KEMP, Scott Jeffrey , LEVY, Odile Esther , LIM-WILBY, Marguerita , TAMURA, Susan Y. , WU, Wanli , HENDRATA, Siska , HUANG, Yuhua , WONG, Jesse K. , NAIR, Latha G.
CPC分类号： C07K5/0804 , A61K38/00 , C07K5/0202 , C07K5/0812 , C07K5/0827 , C07K7/02
摘要： The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.
-
4.发明公开
公开(公告)号：EP2035416A1
公开(公告)日：2009-03-18
申请号：EP07796521.8
申请日：2007-06-27
发明人： MA, Yao , LAHUE, Brian, R. , SHIPPS, JR., Gerald, W. , WANG, Yaolin , BOGEN, Stephane, L. , VOSS, Matthew. E. , NAIR, Latha, G. , TIAN, Yuan , DOLL, Ronald, J. , GUO, Zhuyan , STRICKLAND, Corey, O. , ZHANG, Rumin , MCCOY, Mark, A. , PAN, Weidong , SIEGEL, Elise, M. , GIBEAU, Craig, R.
IPC分类号： C07D409/14 , C07D401/06 , C07D401/14 , A61P35/00 , A61K31/496 , A61K31/506
CPC分类号： C07D409/14 , C07D401/06 , C07D401/14
摘要： In its many embodiments, the present invention discloses novel compounds, as inhibitors of HDM2 protein, methods for preparing such compounds, pharmaceutical compositions including one or more such compounds, methods of treatment, prevention, inhibition, of one or more diseases associated with the HDM2 protein or P53 using such compounds or pharmaceutical compositions.
-
公开(公告)号：EP1730165A1
公开(公告)日：2006-12-13
申请号：EP05724112.7
申请日：2005-02-24
申请人： SCHERING CORPORATION
发明人： BOGEN, Stephane, L. , PAN, Weidong , RUAN, Sumei , CHEN, Kevin, X. , ARASAPPAN, Ashok , VENKATRAMAN, Srikanth , NAIR, Latha, G. , SANNIGRAHI, Mousumi , BENNETT, Frank , SAKSENA, Anil, K. , NJOROGE, F., George , GIRIJAVALLABHAN, Viyyoor, M.
IPC分类号： C07K5/02 , C07D209/52 , C07D417/12 , C07D401/12 , C07D409/12 , C07D403/12 , C07D407/12 , C07D413/12 , C07D491/04 , C07D209/70 , C07D495/10 , C07D207/10 , C07D295/16 , A61K31/403 , A61K31/427
CPC分类号： C07D209/52 , A61K38/00 , C07D209/02 , C07D401/12 , C07D403/12 , C07D405/12 , C07D409/12 , C07D413/12 , C07D417/12 , C07K5/0205 , C07K5/0808 , C07K5/0812 , C07K5/0827
摘要： The present invention discloses novel compounds of formula (I) which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.
-
6.发明公开NOVEL KETOAMIDES WITH CYCLIC P4'S AS INHIBITORS OF NS3 SERINE PROTEASE OF HEPATITIS C VIRUS 有权与来自丙型肝炎病毒NS3丝氨酸蛋白酶的抗循环P4作为抑制剂NEW酮酰胺
公开(公告)号：EP1730142A1
公开(公告)日：2006-12-13
申请号：EP05723688.7
申请日：2005-02-24
申请人： SCHERING CORPORATION
发明人： CHEN, Kevin, X. , NJOROGE, F., George , SANNIGRAHI, Mousumi , NAIR, Latha, G. , YANG, Weiying , VIBULBHAN, Bancha , VENKATRAMAN, Srikanth , ARASAPPAN, Ashok , BOGEN, Stephane, L. , BENNETT, Frank , GIRIJAVALLABHAN, Viyyoor, M.
IPC分类号： C07D417/12 , C07D513/04 , C07D401/12 , C07D209/52 , C07K5/08 , A61K31/40 , A61P31/12
CPC分类号： C07K5/0202 , A61K31/40 , A61K38/00 , C07K5/0205 , C12Q1/707
摘要： The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.
-
7.发明授权SULFUR COMPOUNDS AS INHIBITORS OF HEPATITIS C VIRUS NS3 SERINE PROTEASE 有权硫化合物AS丙型肝炎病毒的NS3丝氨酸蛋白酶抑制剂的
公开(公告)号：EP1730110B9
公开(公告)日：2011-11-02
申请号：EP05723607.7
申请日：2005-02-24
申请人： Schering Corporation
发明人： BENNETT, Frank , LOVEY, Raymond G. , HUANG, Yuhua , HENDRATA, Siska , SAKSENA, Anil, K. , BOGEN, Stephane, L. , LIU, Yi-Tsung , NJOROGE, F., George , VENKATRAMAN, Srikanth , CHEN, Kevin, X. , SANNIGRAHI, Mousumi , ARASAPPAN, Ashok , GIRIJAVALLABHAN, Viyyoor, M. , VELAZQUEZ, Francisco , NAIR, Latha
IPC分类号： C07D209/52 , C07D209/56 , C07D491/04 , C07K5/08 , C07K5/02 , A61K31/403 , A61K31/407 , A61P31/12
CPC分类号： C07D209/52 , A61K38/00 , C07D207/16 , C07D209/56 , C07D405/12 , C07D409/12 , C07D411/12 , C07D491/04 , C07K5/0202
摘要： The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.
-
8.发明公开SULFUR COMPOUNDS AS INHIIBITORS OF HEPATITIS C VIRUS NS3 SERINE PROTEASE 有权硫化合物AS丙型肝炎病毒的NS3丝氨酸蛋白酶抑制剂的
公开(公告)号：EP2134739A2
公开(公告)日：2009-12-23
申请号：EP08742663.1
申请日：2008-04-08
申请人： Schering Corporation
发明人： VELAZQUEZ, Francisco , BOGEN, Stephane, L. , ARASAPPAN, Ashok , VENKATRAMAN, Srikanth , NJOROGE, F., George , SHIH, Neng-Yang
IPC分类号： C07K5/08
CPC分类号： C07K5/0202 , A61K38/05 , C07D209/52 , C07D401/12 , C07D403/12 , C07D417/12 , C07K5/06008 , C07K5/0804 , A61K2300/00
摘要： The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.
-
9.发明公开
公开(公告)号：EP1748983A2
公开(公告)日：2007-02-07
申请号：EP05723589.7
申请日：2005-02-24
申请人： SCHERING CORPORATION
发明人： VENKATRAMAN, Srikanth , NJOROGE, F., George , BLACKMAN, Melissa, L. , WU, Wanli , NAIR, Latha, G. , ARASAPPAN, Ashok , BOGEN, Stephane, L. , CHEN, Kevin, X. , SANNIGRAHI, Mousumi , BENNETT, Frank , GIRIJAVALLABHAN, Viyyoor, M.
IPC分类号： C07D209/52 , C07D403/12 , C07D401/12 , C07D417/12 , C07K5/08 , A61K31/40 , A61K31/4025 , A61K38/06 , A61P31/12
CPC分类号： C07D209/52 , A61K38/00 , C07D401/12 , C07D403/12 , C07D409/12 , C07D417/12 , C07K5/06034 , C07K5/06078
摘要： The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.
-
10.发明公开PROLINE COMPOUNDS AS NS3-SERINE PROTEASE INHIBITORS FOR USE IN TREATMENT OF HEPATITIS C VIRUS INFECTION 有权脯氨酸AS NS3丝氨酸蛋白酶抑制剂，其用于丙型肝炎病毒感染的控制
公开(公告)号：EP1467989A1
公开(公告)日：2004-10-20
申请号：EP03705843.5
申请日：2003-01-21
申请人： SCHERING CORPORATION
发明人： ARASAPPAN, Ashok , BENNETT, Frank , BOGEN, Stephane, L. , CHEN, Kevin, X. , JAO, Edwin , LIU, Yi-Tsung , LOVEY, Raymond, G. , MADISON, Vincent, S. , NAIR, Latha, G. , NJOROGE, F., George , SAKSENA, Anil, K. , SANNIGRAHI, Mousumi , VENKATRAMAN, Srikanth , GIRIJAVALLABHAN, Viyyoor, M.
IPC分类号： C07D403/12 , A61K38/55 , A61P31/12
CPC分类号： C07D207/27 , C07D207/16 , C07D209/08 , C07D209/42 , C07D211/26 , C07D211/34 , C07D211/70 , C07D213/75 , C07D217/26 , C07D233/68 , C07D243/12 , C07D253/06 , C07D271/06 , C07D277/06 , C07D277/46 , C07D277/56 , C07D295/15 , C07D307/68 , C07D317/58 , C07D335/10 , C07D401/04 , C07D401/14 , C07D403/12 , C07D405/06 , C07D405/12
摘要： The present invention discloses novel compounds of Formula I which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.
-
-
-
-
-
-
-
-
-
搜索结果
22 条记录 (耗时 0.021 秒)
