公开(公告)号：EP1337830A2

公开(公告)日：2003-08-27

申请号：EP01988221.6

申请日：2001-11-30

申请人： Auburn University

发明人： VODYANOY, Vitaly, J. ,  BARBAREE, James, M. ,  CHIN, Bryan, S. ,  NEELY, William, Charles ,  BRADEN, Timothy, D. ,  PATHIRANA, Suram, T.

IPC分类号： G01N1/30

CPC分类号： A01N1/0221 ,  A01N1/02 ,  A01N1/0231 ,  G01N1/30 ,  G01N33/548

摘要： Compositions and methods for the reversible preservation of biological samples are provided. The compositions include Acacia Gum, including derivations and modifications thereof which are useful as a reversible preservation solution. A method is provided for using Acacia Gum to isolate and reversibly preserve a biological specimen in a dormant state at room temperature for an extended period with minimal damage to the specimen. The compositions and methods disclosed may also be used to create reversibly preserved biological specimens and biological receptors for use in biosensors.

公开(公告)号：EP1263934A1

公开(公告)日：2002-12-11

申请号：EP01913108.5

申请日：2001-02-28

申请人： AUBURN UNIVERSITY ,  UNIVERSITY OF CENTRAL FLORIDA

发明人： DANIELL, Henry ,  LEE, Seung-Bum ,  BYUN, Myung, Ok

IPC分类号： C12N5/10 ,  C12N15/82 ,  C12N5/04 ,  A01H4/00

CPC分类号： C12N15/8273 ,  C12N15/8214 ,  C12N15/8243 ,  C12N15/8245

摘要： This invention provides a method of conferring osmoprotection to plants. Plant plastid genomes, particularly the chloroplast genome, is transformed to express an osmoprotectant. The transgenic plants and their progeny display drought resistance. More importantly, such transgenic plants display no negative pleiotropic effects such as sterility or stunted growth.

公开(公告)号：EP1263281A1

公开(公告)日：2002-12-11

申请号：EP01918264.1

申请日：2001-02-28

申请人： AUBURN UNIVERSITY ,  UNIVERSITY OF CENTRAL FLORIDA

发明人： DANIELL, Henry ,  MOAR, William

IPC分类号： A01H5/02 ,  A01H5/10 ,  A01H13/00 ,  C12N1/20 ,  C12N1/12 ,  C12N5/04 ,  C12N15/29 ,  C12N15/32 ,  C12N15/52 ,  C12N15/31 ,  C12N15/17 ,  C12N15/13 ,  C12N15/63 ,  C12N15/74 ,  C12N15/82

CPC分类号： C07K14/325 ,  C12N15/79 ,  C12N15/8214 ,  C12N15/8241 ,  C12N15/8259 ,  C12N15/8271 ,  C12N15/8286 ,  Y02A40/162

摘要： Introducing blocks of foreign genes in a single operon would avoid complications such as position effect and gene silencing inherent in putting one gene at a time into random locations in the nuclear genome. Cloning several genes into a single T-DNA does not avoid the compounded variable expression problem encountered in nuclear transgenic plants. This disclosure shows that a bacterial operon can be expressed in a single integration event as opposed to multiple events requiring several years to accomplish. Expression of multiple genes via a single transformation event opens the possibility of expressing foreign pathways or pharmaceutical proteins involving multiple genes. Expressing the Cry2aA2 operon, including a putative chaperonin to aid in protein folding, in the chloroplast via a single transformation event leads to production of crystalized insecticidal proteins. Expressing the Mer operon via a single transformation event leads to a phytoremediation system.

公开(公告)号：EP1105484A1

公开(公告)日：2001-06-13

申请号：EP99945101.6

申请日：1999-08-19

申请人： AUBURN UNIVERSITY

发明人： CUPP, Eddie, Wayne ,  CUPP, Mary, Smith

IPC分类号： C12N15/15 ,  C07K14/81 ,  C12N1/21 ,  C12N5/10 ,  C07K16/38 ,  A61K38/57 ,  A61K38/48

CPC分类号： C07K14/811 ,  A61K39/00 ,  A61K2039/51

摘要： Compositions and methods for preventing hematophagous infestation of cattle are provided, directed at isolated proteins with antithrombin activity and nucleotide sequences encoding the proteins. The proteins named thrombostasin is isolated from the salivary glands of Haematobia irritans. The compositions are useful as veterinary vaccines in prevention of blood-feeding in cattle by the infesting horn fly. The proteins of the invention are also useful in treatment of thrombosis.

公开(公告)号：EP0999908A1

公开(公告)日：2000-05-17

申请号：EP98940816.6

申请日：1998-08-07

申请人： ABB LUMMUS GLOBAL INC. ,  AUBURN UNIVERSITY

发明人： OVERBEEK, Rudolf, A. ,  KHONSARI, Ali, M. ,  CHANG, Yung-Feng ,  MURRELL, Lawrence, L. ,  TATARCHUK, Bruce, J. ,  MEFFERT, Michael, W.

IPC分类号： B22F3/00

CPC分类号： C04B30/02 ,  B01J35/06 ,  B01J2208/00884 ,  B22F3/002 ,  B22F3/1121 ,  C04B2111/0081 ,  C04B14/46 ,  C04B24/383 ,  C04B40/0268 ,  C04B14/386 ,  C04B14/48 ,  C04B38/0675 ,  C04B40/0263

摘要： A porous composite product comprised of a network of fibers is produced by forming an unsintered preformed network of fibers and a gasifiable structure forming agent, followed by gasification of the structure forming agent prior to sintering of the fibers at appropriate junction points. The preferred structure forming agent is a cellulosic material.

公开(公告)号：EP0792271A1

公开(公告)日：1997-09-03

申请号：EP95941407.0

申请日：1995-11-13

申请人： GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. ,  THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL ,  AUBURN UNIVERSITY

发明人： BOYKIN, David, W. ,  DYKSTRA, Christine, C. ,  TIDWELL, Richard R., Route 3 Box 212K ,  HALL, James, E. ,  WILSON, W., David ,  KUMAR, Arvind ,  BLAGBURN, Byron, L.

IPC分类号： C07D307 ,  A61K31 ,  A61P11 ,  A61P29 ,  A61P33 ,  C07D405

CPC分类号： A61K31/506 ,  A61K31/341 ,  A61K31/4178 ,  C07D307/54 ,  C07D307/58 ,  C07D405/14 ,  Y02A50/488 ,  Y02A50/491

摘要： The present invention provides methods for treating Pneumocystis carinii pneumonia, Giardia lamblia, and Cryptosporidium parvum in a subject in need of such treatment. The methods comprise administering to the subject a compound of formula (I), wherein R1 and R2 are each independently selected from the group consisting of H, loweralkyl, aryl, alkylaryl, aminoalkyl, aminoaryl, halogen, oxyalkyl, oxyaryl, or oxyarylalkyl; R3 and R4 are each independently selected from the group consisting of H, loweralkyl, oxyalkyl, alkylaryl, aryl, oxyaryl, aminoalkyl, aminoaryl, or halogen; and X and Y are located in the para or meta positions and are selected from the group consisting of H, loweralkyl, oxyalkyl, and (a) wherein each R5 is independently selected from the group consisting of H, loweralkyl, alkoxyalkyl, hydroxyalkyl, aminoalkyl, alkylaminoalkyl, cycloalkyl, aryl, or alkylaryl or two R5 groups together represent C2-C10 alkyl, hydroxyalkyl, or alkylene; and R6 is H, hydroxy, loweralkyl, alkoxyalkyl, hydroxyalkyl, aminoalkyl, alkylamino, alkylaminoalkyl, cycloalkyl, hydroxycycloalkyl, alkoxycycloalkyl, aryl, or alkylaryl; or a pharmaceutically acceptable salt thereof. The compounds are administered in an amount effective to treat the condition. The present invention also includes novel compounds useful in the treatment of Pneumocystis carinii pneumonia, Giardia lamblia, and Cryptosporidium parvum.

公开(公告)号：EP0748223A1

公开(公告)日：1996-12-18

申请号：EP94911555.0

申请日：1994-03-11

申请人： AUBURN UNIVERSITY

发明人： WORLEY, Shelby, D. ,  SUN, Gang ,  SUN, Wanying ,  CHEN, Tay-Yuan

IPC分类号： A01N59 ,  C07D251 ,  C08F8

CPC分类号： A01N59/00 ,  C07D251/20 ,  C08F8/30

摘要： Cyclic N-halamine biocidal polymer compounds and methods of using the same wherein the functional groups halogenated hydantoins, triazine diones, imidazolidinones, and pyrimidinones are substituted onto inexpensive polymer units such as polystyrene, polyethylene, and modified polymethacrylamide are provided. These N-halamine polymers are stable, insoluble biocides which release only small amounts of free halogen and other impurities. They will be useful as disinfectants for potable water, swimming pools, hot tubs, industrial water systems, cooling towers, air-conditioning systems, gas streams, paints, oils, ointments, fabrics, sterile bandages, coatings, hard surfaces, liners of containers, and the like.

公开(公告)号：EP0473715A4

公开(公告)日：1992-12-30

申请号：EP90909260

申请日：1990-05-24

申请人： AUBURN UNIVERSITY

发明人： TATARCHUK, BRUCE, J. ,  ROSE, MILLARD, F. ,  KRISHNAGOPALAN, ARAVAMUTHAN ,  ZABASAJJA, JOHN, N. ,  KOHLER, DAVID, A.

IPC分类号： B22F3/00 ,  D04H1/42 ,  H01G9/00 ,  H01G9/155 ,  B32B15/14 ,  B32B5/08

CPC分类号： H01G9/155 ,  B22F3/002 ,  D04H1/4209 ,  D04H1/4234 ,  D04H1/4242 ,  D04H1/4382 ,  H01G11/58 ,  H01G11/72 ,  Y02E60/13 ,  Y10S264/75

摘要： A family of composites are characterized as a network of a first fiber and at least a second fiber, where at least the first fibers have a multiplicity of bonded junctions at their point of crossing. The largest class has metals as one or both of the fibers, although the second fiber can be of materials such as carbon, ceramics, and high surface area materials. The composites can be simply prepared and manifest enormous variation in such properties as void volume, pore size, and electrical properties generally.

公开(公告)号：EP4217542A1

公开(公告)日：2023-08-02

申请号：EP21873554.6

申请日：2021-09-24

申请人： Auburn University

发明人： POWELL, Raymond L. ,  NELSON, Jason

IPC分类号： E01C23/10 ,  E01C21/00 ,  E01C23/06 ,  E01C5/12

公开(公告)号：EP4189138A1

公开(公告)日：2023-06-07

申请号：EP21758527.2

申请日：2021-07-29

申请人： Auburn University

发明人： ZHANG, Xinyu ,  ADAMCZYK, Andrew ,  SARWAR, Shatila ,  ALI, Ashraf

IPC分类号： C25B1/04 ,  C25B11/054 ,  C25B11/065 ,  C25B11/075