公开(公告)号：EP2328683B1

公开(公告)日：2019-11-27

申请号：EP09781710.0

申请日：2009-08-11

申请人： Nexus Biosystems, Inc.

发明人： PINK, Rosa ,  BERGER, Martin

IPC分类号： B01L3/14 ,  G06K1/12

公开(公告)号：EP3551312A1

公开(公告)日：2019-10-16

申请号：EP17878672.9

申请日：2017-12-07

申请人： Reaction Analytics, Inc.

发明人： LOPEZ, Michael, Antonio

IPC分类号： B01D35/02 ,  B01D33/00 ,  B01D33/01 ,  B01D35/00 ,  B01L3/00 ,  B01L3/14

公开(公告)号：EP3536403A1

公开(公告)日：2019-09-11

申请号：EP18160393.7

申请日：2018-03-07

申请人： Eppendorf AG

发明人： BLUMENTRITT, Michael ,  HOLL, Kai

IPC分类号： B01L3/14 ,  B65D51/16

摘要： Deckelgefäß aus Kunststoff für den Laboreinsatz umfassend
• ein röhrenförmiges Gefäß, das unten einen Gefäßboden, oben eine Gefäßöffnung und unterhalb der Gefäßöffnung an der Innenwand einen Dichtbereich aufweist,
• einen Deckel, der einen Deckelboden und einen von der Innenseite des Deckelbodens vorstehenden Stopfen aufweist, der durch die Gefäßöffnung in eine Abdichtposition einsetzbar ist, in der der Stopfen abdichtend am Dichtbereich anliegt,
wobei
• der Deckel in einer Parkposition mit dem Stopfen in die Gefäßöffnung eingreift, ohne abdichtend am Dichtbereich anzuliegen, und
• eine erste Rasteinrichtung zum lösbaren Verrasten des Deckels mit dem Gefäß in der Parkposition vorhanden ist.

公开(公告)号：EP3173021B1

公开(公告)日：2019-03-27

申请号：EP16200112.7

申请日：2013-05-30

申请人： Magnolia Medical Technologies, Inc.

发明人： BULLINGTON, Gregory J. ,  PATTON, Richard G. ,  MIAZGA, Jay M. ,  GAW, Shan E.

IPC分类号： A61B5/15 ,  B01D43/00 ,  B01L3/14 ,  C12M1/00 ,  C12N5/02 ,  G01N33/49 ,  A61B5/153

公开(公告)号：EP3427833A1

公开(公告)日：2019-01-16

申请号：EP18000584.5

申请日：2018-07-09

申请人： Lind, Victor ,  Fedotov, Maxim

发明人： Lind, Victor ,  Fedotov, Maxim ,  Dorofeikov, Vladimir

IPC分类号： B01L3/14 ,  G01N33/49 ,  A61B5/154

摘要： The device for blood sample preparation for determining the concentration of glucose in the blood plasma relates to medicine, more specifically to clinical laboratory diagnostics and endocrinology, and can be used for the diagnosing of diabetes mellitus.
The device is a vacuum vial with a bar code and a protective cover of grey colour assembled with a rubber stopper comprising an inert separation gel in an amount of 0.6-1.2 g at the bottom and a mixture of potassium oxalate with sodium fluoride on the walls of the vial.
The device provides increased accuracy of determining the glucose concentration in blood plasma, reduces the time of sample preparation, reduces the risk of haemolysis during transportation and storage of blood, and reduces the risk of infection of laboratory personnel with blood-borne infections.

公开(公告)号：EP3386391A1

公开(公告)日：2018-10-17

申请号：EP16874075.1

申请日：2016-12-12

申请人： Siemens Healthcare Diagnostics Inc.

发明人： OLSON, Eric

IPC分类号： A61B5/15 ,  A61B10/00 ,  B01L3/14 ,  B65D39/04 ,  B01L3/00 ,  A61B5/154

CPC分类号： B01L3/50215 ,  A61B5/15003 ,  A61B5/154 ,  B01L2300/042 ,  B01L2300/044 ,  B01L2300/047 ,  B01L2300/0832

摘要： A device and method for separating serum or plasma from blood cells in a whole blood specimen. The present invention uses a cap with a reservoir, such that blood cells are packed into the cap when the specimen container is centrifuged. When the cap is removed, the blood cells are also removed, and the serum or plasma is left in the specimen tube where it can be readily extracted by a pipette which is able to reach all the way to the bottom of the specimen tube minimizing the dead volume.

公开(公告)号：EP2810717B1

公开(公告)日：2018-10-17

申请号：EP14166982.0

申请日：2014-05-05

申请人： F. Hoffmann-La Roche AG ,  Roche Diagnostics GmbH

发明人： Burghardt, Geza ,  Glauser, Michael ,  Gutmann, Oliver ,  Müller, Daniel ,  Oosterbroek, Rijk Edwin ,  Sandoz, Roger ,  Sarofim, Emad ,  Savatic, Goran

IPC分类号： B01L3/14 ,  B01L3/00

CPC分类号： G01P15/02 ,  B01L3/5021 ,  B01L3/5453 ,  B01L2200/14 ,  B01L2200/143 ,  B01L2300/021 ,  B01L2300/025 ,  B01L2300/0663 ,  B01L2400/0409

摘要： An acceleration sensitive indicator (1, 1', 1", 31, 31', 51, 61, 71, 81, 121, 121', 131) for indicating a centrifugation status of a biological sample, a sample container (100, 100') comprising the acceleration sensitive indicator, a centrifuge (200) for centrifuging sample containers (100, 100') and an analytical system (300) for analyzing centrifuged samples are disclosed. The indicator (1, 1', 1", 31, 31', 51, 61, 71, 81, 121, 121', 131) comprises at least one closed chamber (2, 2', 32, 32', 112) formed between two opposite surfaces. The chamber (2, 2', 32, 32', 112) comprises at least one indication zone (3, 3', 3", 33, 53, 63, 73, 93, 123, 124, 124', 133, 134), the at least one indication zone (3, 3', 3", 33, 53, 63, 73, 93, 123, 124, 124', 133, 134) comprising at least two fluid transfer zones (4, 4', 5, 5', 16, 17, 18) or at least one particle transfer zone (34, 54, 74, 75, 76, 77, 82, 122, 125, 125', 135). The at least one fluid transfer zone (4, 4', 5, 5', 16, 17, 18) comprises at least one solid carrier phase (14) and at least one fluid (15, 15') stabilized in the solid carrier phase (14), or at least one non-stabilized non-Newtonian fluid (13) having thixotropic and/or shear thinning properties. The at least one particle transfer zone (34, 54, 74, 75, 76, 77, 82, 122, 125, 125', 135) comprises at least one particle stabilizing fluid (35, 83) comprising stabilized dispersed particles (36, 84, 85, 86, 87). In particular, the at least one fluid (13, 15, 15') or particles (36, 84, 85, 86, 87) have a distribution with respect to the at least one indication zone (3, 3', 3", 33, 53, 63, 73, 93, 123, 124, 124', 133, 134), which is changeable only upon application of a g-force above a threshold value, the change of distribution indicating the centrifugation status.

公开(公告)号：EP2866030B1

公开(公告)日：2018-03-21

申请号：EP14194188.0

申请日：2009-12-02

申请人： The Regents of the University of California ,  The University Of Maryland

发明人： Emerson, Jane ,  Sun, Kunshan ,  Raghavan, Srinivasa

IPC分类号： G01N33/49 ,  C12Q1/24 ,  C12M1/24 ,  C12M1/10 ,  A61B5/15 ,  B01L3/14 ,  G01N15/04 ,  A61M1/36 ,  B01D21/26 ,  B01L3/00

CPC分类号： B01L3/50215 ,  B01D21/26 ,  B01L3/5021 ,  B01L2200/0647 ,  B01L2200/10 ,  B01L2300/0832 ,  B01L2300/12 ,  B01L2300/1861 ,  B01L2400/0409 ,  B01L2400/0677 ,  B01L2400/086 ,  G01N33/491

摘要： Contemplated compositions and methods allow for in-situ formation of a rigid seal layer in a blood collection tube between a cell-depleted phase and a cell-enriched phase. Preferably, the seal layer is formed upon brief UV irradiation and comprises an acrylate, a methacrylate, an epoxy, a urethane, and/or a thiol-ene polymer.

公开(公告)号：EP2457631B1

公开(公告)日：2018-03-07

申请号：EP12000169.8

申请日：2008-08-27

申请人： Millipore Corporation

发明人： Bonhomme, Louis ,  Doyle, John ,  Greenizen, Kurt ,  Gagne, George ,  Devin, Sean ,  Lombard, Gerard ,  Smith, Vincent

IPC分类号： B01D61/18 ,  B01D63/16 ,  B01L3/14

CPC分类号： B01D63/16 ,  B01D61/145 ,  B01D61/18 ,  B01D63/08 ,  B01D2313/08 ,  B01L3/502 ,  B01L3/5021 ,  B01L3/5635 ,  B01L2300/0681

摘要： The invention pertains to a filtration device (10), comprising a central jacket and first and second side panels interlocked together around said jacket, each of said side panels comprising a membrane (12A,12B) sealed thereto. The invention further pertains to a combination of said filtration device and a vial comprising an interior volume configured to receive said filtration device in a first orientation effective for concentrating sample in said sample chamber when subjected to a driving force, and in a second orientation effective for recovering concentrated sample when subjected to a driving force.

公开(公告)号：EP3259068A1

公开(公告)日：2017-12-27

申请号：EP16752907.2

申请日：2016-02-16

申请人： Siemens Healthcare Diagnostics Inc.

发明人： KLUCKNER, Stefan ,  CHANG, Yao-Jen ,  WU, Wen ,  POLLACK, Benjamin ,  CHEN, Terrence

IPC分类号： B01L3/14 ,  G01N21/01 ,  G06K9/72 ,  G06K9/78

CPC分类号： G06K9/629 ,  B01L3/5453 ,  G01N35/00732 ,  G01N2035/00752 ,  G06K7/1439 ,  G06K7/1491 ,  G06K2209/19

摘要： Barcode tag conditions on sample tubes are detected utilizing side view images of sample tubes for streamlining handling in clinical laboratory automation systems. The condition of the tags may be classified into classes, each divided into a list of additional subcategories that cover individual characteristics of the tag quality. According to an embodiment, a tube characterization station (TCS) is utilized to obtain the side view images. The TCS enables the simultaneous or near-simultaneous collection of three images for each tube, resulting in a 360 degree side view for each tube. The method is based on a supervised scene understanding concept, resulting in an explanation of each pixel into its semantic meaning. Two parallel low-level cues for condition recognition, in combination with a tube model extraction cue, may be utilized. The semantic scene information is then integrated into a mid-level representation for final decision making into one of the condition classes.