摘要:
The compact microspectrometer for fluid media has, in a fixed spatial assignment in a housing (20b), a light source, a fluid passage (28b), a reflective optical grating (38b) and a detector (40b). The optical measurement path starting from the light source passes through the fluid passage and strikes the optical grating. The spectral light components which are reflected by the optical grating strike the detector.
摘要:
An optical instrument monitors PCR replication of DNA in a reaction apparatus having a temperature cycled block with vials of reaction ingredients including dye that fluoresces in presence of double-stranded DNA. A beam splitter passes an excitation beam to the vials to fluoresce the dye. An emission beam from the dye is passed by the beam splitter to a CCD detector from which a processor computes DNA concentration. A reference strip with a plurality of reference emitters emit reference beams of different intensity, from which the processor selects an optimum emitter for compensating for drift. Exposure time is automatically adjusted for keeping within optimum dynamic ranges of the CCD and processor. A module of the beam splitter and associated optical filters is associated with selected dye, and is replaceable for different dyes.
摘要:
Es wird ein integriertes Testelement (110) zum Nachweis mindestens eines Analyten in einer Probe (142), insbesondere einer flüssigen Probe (142), vorgeschlagen. Das integrierte Testelement (110) weist ein Trägerelement (112) auf, mit einer Applikationsseite (114), auf der mindestens ein organisches elektrolumineszierendes Bauelement (126) aufgebracht ist. Weiterhin ist auf der Applikationsseite (114) mindestens eine Indikatorsubstanz (136) aufgebracht, welche mindestens eine optische Eigenschaft, insbesondere eine Emissionseigenschaft (z. B. eine Fluoreszenzeigenschaft), ändert, wenn diese in Kontakt mit dem mindestens einen Analyten gerät. Weiterhin weist das integrierte Testelement (110) mindestens ein Photodetektor-Element (116) auf.
摘要:
Fluorescence-based sensors having favourably low detection limits and high sensitivity are disclosed. The sensors comprise one or more solution processable colour filters that are used together with organic LEDs and photodiodes. The colour filters are used to narrow the wavelength range of the OLED emission and/or to reject any light from reaching the photodiode which is not from analyte fluorescence, thereby enhancing the device sensitivity.
摘要:
An optical instrument (A) for monitoring polymerase chain reaction replication of DNA may include a thermal cycler block (1c) for holding a plurality of vials (1b), each containing a suspension of ingredients that include a fluorescent primary dye. The instrument may include a light source (11) for emitting a source beam, a first means (7) disposed to be receptive of the source beam, a primary focusing means (3) disposed to focus the excitation beam simultaneously into a plurality of suspensions and being receptive of and passing emission beams, a second means (8) disposed to be receptive of emission beams, an emission focusing means (10) for focusing emission beams, a detector, and a processing means for computing concentration of DNA. The optical system being arranged without a beam splitter (6) but with one or more folding mirrors (5), and with excitation and emission beams being on slightly different optical paths angularly.
摘要:
Cell culturing and tracking systems using an array of organic light emitting diodes (OLEDs) to illuminate cells and/or other particles in a cell chamber are described. Compared to conventional light sources, the OLED array consumes very little energy and emits a small amount of waste heat, so it may be disposed near or on the cell chamber. For instance, it can be printed on one side of the cell chamber itself. In addition, the OLED array may be patterned into pixels or sub-pixels (individual OLEDs), each of which is as small as or smaller than an individual cell or particle. Because the pixels are so small, OLED illumination can be used to acquire images with a spatial resolution equal to or better than the cell or particle cell. As a result, the OLED array can be used to track, monitor, identify, and manipulate individual cells within the cell culture.
摘要:
A sensor device configured to be attached to a drug delivery device and configured to illuminate the drug delivery device when attached, the sensor device having an OLED having a transparent first electrode, a transparent second electrode and a central layer disposed between the first and second electrodes, the central layer comprising at least one organic layer, the at least one organic layer configured to emit light through the transparent first electrode, and an optical sensor arranged to receive light reflected from a surface of the drug delivery device, wherein the central layer of the OLED has a region without the at least one organic layer and wherein the optical sensor is arranged, when the sensor device is attached to the drug delivery device, to view a predetermined area of the surface of the drug delivery device through the region without the at least one organic layer.