公开(公告)号：EP1827501A2

公开(公告)日：2007-09-05

申请号：EP05855832.1

申请日：2005-12-21

Applicant: Nektar Therapeutics Al, Corporation

Inventor： MCMANUS, Samuel ,  KOZLOWSKI, Antoni

IPC: A61K47/48 ,  C07C323/12 ,  C07D213/70

CPC classification number: A61K47/48215 ,  A61K31/415 ,  A61K47/60 ,  C07C323/12 ,  C07D213/70 ,  C07D213/71

Abstract: Disclosed are water soluble polymeric reagents comprising the structure POLY-[Y-S-W]x,, where POLY is a water soluble polymer; Y is a hydrocarbon­based spacer group, x is 1 to 25, and S-W is a thiol, protected thiol, or thiol-reactive derivative. Preferably, the water soluble polymer is a PEG polymer. Also disclosed are conjugates of such polymeric reagents with pharmaceutically relevant molecules, and methods of their formation and use.

公开(公告)号：EP1470105B1

公开(公告)日：2007-05-16

申请号：EP03701601.1

申请日：2003-01-27

Applicant: QinetiQ Limited

Inventor： KELLY, Stephen Malcom, Merck NBSC, Chilworth ,  DUFFEY,Warren Lee, Merck NBSC, Chilworth ,  CAMPBELL, Neil L., Yokoyama, Nano-structured

IPC: C07C323/62 ,  C07C323/12 ,  C07C255/50 ,  C07C255/55 ,  C07C43/225 ,  C07C43/192 ,  C07C69/92 ,  C07C69/757 ,  C09K19/12 ,  C09K19/14 ,  C09K19/16 ,  C09K19/18 ,  C09K19/20 ,  C09K19/30

CPC classification number: C09K19/3003 ,  C09K19/12 ,  C09K19/14 ,  C09K19/16 ,  C09K19/18 ,  C09K19/2007 ,  C09K19/3028 ,  C09K19/3048 ,  C09K19/3059 ,  C09K19/3068 ,  C09K2019/0444

Abstract: A compound of formula (I): where R1 is alkyl or alkenyl, Y1 and Y2 are independently selected from oxygen or sulphur, n is an integer of from 1 to 5, A is an optionally substituted phenyl or an optionally substituted cycloalkyl ring, X is a direct bond, a C1-4alkylene, a C2-4alkenylene, an acetylene, -CO(O)- or a group of sub-formula (i): where X1 and X2 are independently selected from a direct bond, a C1-4alkylene, a C2-4alkenylene, an acetylene, -CO(O)- and R2, R3 and R4 are independently selected from hydrogen, halo or cyano, provided that no more than one of R2, R3 and R4 is hydrogen. These compounds have a high dipole moment and may be used as dopants in liquid crystal mixtures.

公开(公告)号：EP1249446B1

公开(公告)日：2007-03-07

申请号：EP02005809.5

申请日：2002-03-14

Applicant: FIRMENICH SA

Inventor： Van de Waal, Matthijs ,  Escher, Sina, Dorothea ,  Niclass, Yvan

IPC: C07C323/12 ,  C07C323/28 ,  C11B9/00 ,  A23L1/226

CPC classification number: C07C327/28 ,  C07C323/12 ,  C11B9/0011

公开(公告)号：EP1584986B1

公开(公告)日：2007-01-03

申请号：EP05251131.8

申请日：2005-02-25

Applicant: SAMSUNG ELECTRONICS CO., LTD.

Inventor： Tokarski, Zbigniew ,  Montrimas, Edmundas ,  Malinauskas, Tadas ,  Jubran, Nusrallah ,  Jankauskas, Vygintas ,  Getautis, Vytautas

IPC: G03G5/06 ,  G03G5/07 ,  C07C323/12 ,  C08G65/48 ,  C08G75/20 ,  C08G75/08 ,  C08F12/36

CPC classification number: G03G5/071 ,  G03G5/062 ,  G03G5/075 ,  H01L51/0035

公开(公告)号：EP1201648A4

公开(公告)日：2006-08-02

申请号：EP00949984

申请日：2000-08-03

Applicant: KUMIAI CHEMICAL INDUSTRY CO ,  IHARA CHEMICAL IND CO

Inventor： OZAKI MASAMI ,  FUKUMOTO SHUNICHIRO ,  TAMAI RYUJI ,  IKEGAYA KAZUHIRO ,  YONEKURA NORIHISA ,  KAWASHIMA TAKAHIRO ,  SAKAI JUNETSU ,  MURAMATU NORIMICHI ,  TAKAGAKI MAKIKAZU ,  NAGAYAMA KOUZOU

IPC: C07C217/20 ,  A01N47/12 ,  A01N47/28 ,  A01P3/00 ,  C07C271/20 ,  C07C271/22 ,  C07C275/24 ,  C07C317/18 ,  C07C323/12 ,  C07C327/58 ,  C07C327/60 ,  C07C333/04 ,  C07D213/30 ,  C07D213/64 ,  C07D213/70 ,  C07D213/74 ,  C07D213/79 ,  C07D213/84 ,  C07D215/14 ,  C07D237/14 ,  C07D239/26 ,  C07D239/34 ,  C07D277/24 ,  C07D277/64 ,  C07D295/08 ,  C07D303/20 ,  C07D333/32 ,  C07D213/65 ,  C07D213/81 ,  C07D215/22

CPC classification number: C07D213/30 ,  A01N47/12 ,  A01N47/28 ,  C07C271/20 ,  C07C271/22 ,  C07C275/24 ,  C07C317/18 ,  C07C323/12 ,  C07C327/58 ,  C07C327/60 ,  C07C333/04 ,  C07D213/64 ,  C07D213/70 ,  C07D213/74 ,  C07D213/79 ,  C07D213/84 ,  C07D215/14 ,  C07D239/26 ,  C07D239/34 ,  C07D277/64 ,  C07D333/32

Abstract: Novel bactericides having an excellent controlling effect on plant disease injury (in particular, wheat powdery mildew and cucumber gray mold) without exerting any undesirable effect on crops. Carbamate derivatives represented by general formula [I] and agricultural/horticultural bactericides containing the same as the active ingredient wherein X represents halogeno, C1-6 alkyl, etc.; n is 0 or an integer of from 1 to 4; R1 represents C¿1-6? alkyl; R?2¿ represents hydrogen, C¿1-6? alkyl, etc.; R?3¿ represents hydrogen or C¿1-6? alkyl; G represents oxygen, sulfur, etc.; Y represents C1-10 alkyl; C2-10 alkenyl, etc.; and Q represents hydrogen, C1-6 haloalkyl, phenyl, etc.

公开(公告)号：EP1674452A1

公开(公告)日：2006-06-28

申请号：EP04773160.9

申请日：2004-09-16

Applicant: CHUGAI SEIYAKU KABUSHIKI KAISHA

Inventor： ISSHIKI, Yoshiaki, c/o CHUGAI SEIYAKU K.K. ,  KOHCHI, Yasunori, c/o CHUGAI SEIYAKU K.K. ,  HATTORI, Kazuo, c/o CHUGAI SEIYAKU K.K. ,  SHIMMA, Nobuo, c/o CHUGAI SEIYAKU K.K. ,  MIWA, Masanori, c/o CHUGAI SEIYAKU K.K. ,  INAGAKI, Naohito, c/o CHUGAI SEIYAKU K.K. ,  IIKURA, Hitoshi, c/o CHUGAI SEIYAKU K.K. ,  MATSUBARA, Yasuaki, c/o CHUGAI SEIYAKU K.K.

IPC: C07C259/10 ,  C07C229/58 ,  C07C251/48 ,  C07C311/04 ,  C07C317/18 ,  C07C323/12 ,  C07D207/08 ,  C07D207/26 ,  C07D211/46 ,  C07D213/30 ,  C07D233/34 ,  C07D233/64 ,  C07D295/08 ,  C07F7/18 ,  A61K31/166 ,  A61K45/00 ,  A61P1/00 ,  A61P1/16 ,  A61P1/18 ,  A61P3/10

CPC classification number: C07D207/08 ,  A61K31/166 ,  C07C259/10 ,  C07C311/04 ,  C07C317/18 ,  C07C323/12 ,  C07C2601/02 ,  C07D207/27 ,  C07D211/46 ,  C07D213/30 ,  C07D233/32 ,  C07D233/64 ,  C07D263/32 ,  C07D295/088 ,  C07D295/155 ,  C07F7/1856

Abstract: A compound of the present invention, or a pharmaceutically acceptable salt thereof is indicated by formula (1) below:

wherein, R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , Q, R 8 , and R 9 have the same meanings as R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , Q, R 8 , and R 9 in the specification.

Abstract translation: 本发明化合物或其药学上可接受的盐由下式（1）表示：其中，R 1，R 2，R 3，R 4，R 5，R 6，Q，R 8和R 9 具有与说明书中的R 1，R 2，R 3，R 4，R 5，R 6，Q，R 8和R 9相同的含义。

公开(公告)号：EP1650186A1

公开(公告)日：2006-04-26

申请号：EP04292517.2

申请日：2004-10-22

Applicant: BIOPROJET ,  Sun Pharmaceuticals Industries Ltd.

Inventor： Capet, Marc ,  Levoin, Nicolas ,  Berrebi-Bertrand, Isabelle ,  Poupardin, Olivia ,  Robert, Philippe ,  Schwartz, Jean-Charles ,  Lecomte, Jeanne-Marie ,  Rajamannar, Thennati ,  Pal, Ranjan Kumar A/4 Shreeji Park Duplex ,  Samanta, Biswajit ,  Jivani, Jignesh K ,  Panchal, Bhavesh M. ,  Bhatt, Isha H. A/3, Satkar Society ,  Aradhye, Jayraj D.

IPC: C07C229/30 ,  C07C229/48 ,  C07C237/24 ,  C07C323/12 ,  A61K31/10 ,  A61K31/165 ,  A61K31/196 ,  A61K31/197 ,  A61K31/216 ,  A61P37/06

CPC classification number: C07C237/24 ,  C07C229/30 ,  C07C229/48 ,  C07C323/12 ,  C07C2601/08

Abstract: The present patent application concerns new compounds of formula (I):

displaying agonistic activity at sphingosine-1-phosphate (S1P) receptors, their process of preparation and their use as immunosuppressive agents.

公开(公告)号：EP1591834A3

公开(公告)日：2005-12-28

申请号：EP05252592.0

申请日：2005-04-26

Applicant: SAMSUNG ELECTRONICS CO., LTD.

Inventor： Tokarski, Zbigniew ,  Sidaravicius, Jonas ,  Jubran, Nusrallah ,  Maldzius, Robertas ,  Getautis, Vytautas ,  Paulauskaite, Ingrida ,  Daskeviciene, Maryte

IPC: G03G5/06 ,  C07C323/12 ,  C07D285/12

CPC classification number: G03G5/0614 ,  C07C323/12 ,  C07D285/125 ,  G03G5/0616 ,  G03G5/0618 ,  G03G5/062 ,  G03G5/0633

Abstract: The present invention provides organophotoreceptors comprising an electrically conductive substrate and a photoconductive element on the electrically conductive substrate, the photoconductive element comprising:

(a) a charge transport material having the formula
where X comprises a linking group;
   R 1 and R 1 ' comprise, each independently, H, an alkyl group, an alkenyl group, an alkynyl group, an aromatic group, or a heterocyclic group; and
   R 2 , R 3 , R 2 ', and R 3 ' comprise, each independently, an arylamine group; and
(b) a charge generating compound.

Corresponding electrophotographic apparatuses, imaging methods (processes), and methods of forming the charge transport material are described, as are charge transport materials.

公开(公告)号：EP0939844B1

公开(公告)日：2005-11-30

申请号：EP98938873.1

申请日：1998-09-02

Applicant: Clariant Finance (BVI) Limited

Inventor： JACKSON, Andrew, Clive

IPC: D21H17/14 ,  D21H21/14 ,  C07C323/52 ,  C07C323/12 ,  C07D239/56 ,  C07D251/38

CPC classification number: C07D239/56 ,  C07C323/12 ,  C07C323/52 ,  C07D251/38 ,  D21H17/06 ,  D21H17/14 ,  D21H21/143

公开(公告)号：EP1149830A4

公开(公告)日：2005-04-27

申请号：EP00979053

申请日：2000-12-01

Applicant: TOKUYAMA CORP

Inventor： MORI KATSUHIRO ,  HARA TADASHI ,  MOMODA JUNJI

IPC: C07C319/14 ,  C07C323/12 ,  C07C323/16 ,  C07C323/52 ,  C07C327/22 ,  C07C329/06 ,  C07C333/04 ,  C07D339/08 ,  C08G75/04 ,  G02B5/23 ,  C07C321/12 ,  C07C321/24 ,  C07C323/10 ,  C07C323/50 ,  C07C327/02 ,  G02B1/04 ,  G02C7/10

CPC classification number: C07C327/22 ,  C07C319/14 ,  C07C329/06 ,  C07C333/04 ,  C07D339/08 ,  C08G75/04 ,  G02B5/23 ,  C07C323/12 ,  C07C323/16 ,  C07C323/52

Abstract: A method of preparing a sulfur-containing compound having at least one thio group in the molecules by reacting a thiol compound with an organic compound having at least one functional group capable of forming a thio group in the molecules upon reacting with a mercapto group in the presence of a basic compound, wherein the number of moles of water contained in the reaction system is set to be not larger than 7.5 times as large as the number of moles obtained by multiplying the number of moles of the thiol compound to be reacted by a number of mercapto groups present in one molecule of the thiol compound.