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公开(公告)号：EP2091960A4
公开(公告)日：2010-11-17
申请号：EP07823214
申请日：2007-10-26
申请人： GLYKOS FINLAND OY
发明人： NATUNEN JARI , HILTUNEN JUKKA , NIEMELAE RITVA , HELIN JARI , AITIO OLLI
IPC分类号： C07K7/06 , A61K31/7028 , A61K38/08 , A61P31/16 , C07H15/00 , C07K14/11 , G01N33/569
CPC分类号： A61K39/145 , A61K38/00 , A61K39/00 , A61K39/12 , A61K2039/64 , C07K5/0815 , C07K5/0821 , C07K14/005 , C12N2760/16122 , C12N2760/16134 , G01N33/56983 , G01N2333/11 , Y10T436/143333
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公开(公告)号：EP2231712A1
公开(公告)日：2010-09-29
申请号：EP08862722.9
申请日：2008-12-18
发明人： KAUKOVIRTA-NORJA, Anu , LEHTINEN, Pekka , VIRKAJÄRVI, Ilkka , SUORTTI, Mikko , MYLLYMÄKI, Olavi , HELIN, Jari , OLONEN, Anne
CPC分类号： C08B37/0024 , A23L2/52 , A23L7/10 , A23L33/22
摘要： The invention relates to a method of degrading plant- based β-glucan into a controlled molecular size by hydro- lyzing β-glucan in a closed space under pressure by means of an acid at an elevated temperature. The invention also relates to a degraded β-glucan product. The β-glucan product obtained is useful in foodstuffs applications, such as beverages.
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公开(公告)号：EP1891437A2
公开(公告)日：2008-02-27
申请号：EP06764482.3
申请日：2006-06-06
发明人： JAATINEN, Taina , HEMMORANTA, Heidi , PARTANEN, Jukka , LAINE, Jarmo , SATOMAA, Tero , NATUNEN, Jari , BLOMQVIST, Maria
IPC分类号： G01N33/50 , G01N33/567 , G01N33/577 , C12N5/06 , C12Q1/68 , C07H3/06
CPC分类号： G01N33/5308 , G01N33/5002 , G01N33/56966
摘要： The present invention relates to a method of profiling a cell population comprising a step of detecting the presence or absence of at least two biological markers in said cell population, wherein at least one of said markers is a cell surface marker, which is a sialylated N-glycan marker with structure NeuNAcα3Gal, and at least one of said markers is a mRNA marker related to glycoproteins and/or glycosynthase proteins. The invention also relates to method for purification of cord blood cell population and to a complete cell population from cord blood purified by said method.
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公开(公告)号：EP1871786A1
公开(公告)日：2008-01-02
申请号：EP06725932.5
申请日：2006-04-20
申请人： Glykos Finland Oy
发明人： ÅNGSTRÖM, Jonas , MILLER-PODRAZA, Halina , PANTZAR, Martina , KARLSSON, Karl-Anders , BLOMQVIST, Maria , HEISKANEN, Annamari , NIEMELÄ, Ritva , HELIN, Jari , NATUNEN, Jari , SATOMAA, Tero , AITIO, Olli
CPC分类号： C07K14/005 , A61K39/00 , A61K39/12 , A61K39/145 , C07H15/04 , C07H15/26 , C07K7/06 , C07K7/08 , C12N2760/16122 , C12N2760/16134 , G01N33/56983
摘要： The invention relates to the method for evaluating the potential of a chemical entity, such as an antibody, to bind to a peptide epitope derived from the divalent sialoside binding site of hemagglutinin protein of influenza virus. The invention also provides peptide epitopes for use in the prevention and/or treatment of influenza or for the development of such treatment or vaccine against influenza.
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公开(公告)号：EP1551880A1
公开(公告)日：2005-07-13
申请号：EP03750750.6
申请日：2003-10-06
申请人： Glykos Finland Oy
发明人： HELIN, Jari , NATUNEN, Jari , LEHTILÄ, Reko , ROSLUND, Mattias , LEINO, Reko
摘要： The present invention is directed to novel methods to produce carbohydrate polymers and oligomers especially for pharmaceutical and food industries. The invention is directed to methods to remodel monosaccharides, and/or oligosaccharides and/or polysaccharides by a different monosaccharide, oligosaccharide or polysaccharide and optionally by further alcohol substances, under condensing conditions, preferably in acid catalysed reactions.
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公开(公告)号：EP3641824B1
公开(公告)日：2022-08-31
申请号：EP18743053.3
申请日：2018-06-20
发明人： SATOMAA, Tero , HELIN, Jari , SAARINEN, Juhani
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公开(公告)号：EP3172333B1
公开(公告)日：2020-05-13
申请号：EP15738703.6
申请日：2015-07-21
申请人： Glykos Finland Oy
发明人： NATUNEN, Jari , LEPPÄNEN, Anne , SALMINEN, Heidi , HILTUNEN, Jukka , KANERVA, Anne , HEISKANEN, Annamari , WESTERHOLM-PARVINEN, Ann , SCHMIDT, Georg , HUUSKONEN, Anne , MUSTALAHTI, Eero , LANDOWSKI, Christopher , SALOHEIMO, Markku , SAARINEN, Juhani , SOMMER, Benjamin Patrick , WAHL, Ramon , OSTERMEIER, Christian , HELK, Bernhard
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公开(公告)号：EP3334751A1
公开(公告)日：2018-06-20
申请号：EP16753633.3
申请日：2016-08-11
申请人： Glykos Finland Oy
IPC分类号： C07K14/37 , C12P21/02 , C12N15/113 , C12N1/15 , C12R1/885
CPC分类号： C07K14/37 , C12N1/14 , C12N9/1051 , C12N15/113 , C12N15/1137 , C12N2310/14 , C12N2310/531 , C12N2330/51 , C12P21/02 , C12Y204/01149 , C12Y204/01258
摘要： The present disclosure relates to compositions and methods useful for the production of heterologous proteins in filamentous fungal cells.
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49.发明授权
公开(公告)号：EP2791164B1
公开(公告)日：2017-08-16
申请号：EP12813390.7
申请日：2012-12-13
申请人： Glykos Finland Oy
发明人： SATOMAA, Tero , SAARINEN, Juhani , NATUNEN, Jari , VILKMAN, Anja , VIRTANEN, Heidi , HILTUNEN, Jukka
CPC分类号： C07K16/2863 , A61K47/48092 , A61K47/549 , A61K2039/505 , C07K16/00 , C07K16/244 , C07K2317/41 , C07K2317/52 , C07K2317/72 , C07K2317/732
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50.发明公开
公开(公告)号：EP3160513A1
公开(公告)日：2017-05-03
申请号：EP15742047.2
申请日：2015-06-26
申请人： Glykos Finland Oy
发明人： HELIN, Jari , SAARINEN, Juhani , SATOMAA, Tero , EKHOLM, Filip S.
摘要： A molecule comprising a saccharide bound via an O-glycosidic bond to a hydroxyl group of a toxic payload molecule is disclosed. An antibody-drug conjugate comprising an antibody covalently bound to a toxic payload molecule, optionally via a linker group, and a saccharide bound via an O-glycosidic bond to a hydroxyl group of the toxic payload molecule is further disclosed.
摘要翻译： 公开了包含通过O-糖苷键与有毒有效负载分子的羟基结合的糖的分子。 进一步公开了一种抗体 - 药物缀合物，其包含共价结合有毒有效负载分子的抗体，任选地通过接头基团和通过O-糖苷键与有毒有效负载分子的羟基结合的糖。
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