摘要:
The present invention relates to derivatives of compounds which are known to be of use in the field of agriculture. These derivatives are differentiated from the parent active compound by virtue of being redox derivatives of the active compound. This means that one or more of the functional groups in the active compound has been converted to another group in one or more changes one or more of which may be considered to represent a change of oxidation state relative to the groups in the original compound. We refer to these compounds generally as redox derivatives. The compounds are of use as insecticides, herbicides and insect repellents.
摘要:
There are provided compounds and methods for the detection of amyloids and treatment of diseases related to amyloids including Alzheimer's disease and other related amyloid-based neurodegenerative diseases.
摘要:
There are provided compounds and methods for the detection of amyloids and treatment of diseases related to amyloids including Alzheimer's disease and other related amyloid-based neurodegenerative diseases.
摘要:
A new process is described for the resolution of racemic verapamil, which allows the desired enantiomer to be obtained in high yields and with high enantiomeric purity. The process uses optically active 2,3-bis[(2-fluorobenzoyl)oxy]butanedioic acid as the resolving agent, and a water/dimethylformamide or water/acetonitrile or water/methanol mixture, as the reaction solvent.
摘要:
A process for producing an erythro-3-amino-2-hydroxybutyric acid derivative characterized in that an erythro-3-amino-2-hydroxybutyronitrile derivative represented by the general formula [II] (wherein R 1 is a straight-chain, branched or cyclic alkyl group having one to six carbon atoms, an alkylthio group or an arylthio group having one to eight carbon atoms, or a substituted or unsubstituted aryl group, P 1 and P 2 are, the same or different, a substituted or unsubstituted aralkyl group, a substituted or unsubstituted aralkyloxycarbonyl group, a substituted or unsubstituted arylcarbonyl group, or a substituted or unsubstituted arylsulfonyl group, and R 2 is an alkylcarbonyl group, or a substituted or unsubstituted arylcarbonyl group), is treated with an acid in water or in a water-containing solvent to convert it into an erythro-3-amino-2-hydroxybutyric acid derivative represented by the general formula [III] (wherein R 1 is the same as mentioned above, R 3 is hydrogen, Q 1 and Q 2 are, the same or different, hydrogen, a substituted or unsubstituted aralkyl group, or a substituted or unsubstituted arylsulfonyl group), or the nitrile derivative is treated with an acid in an alcoholic solvent represented by the general formula of R 3 OH to convert it into an ester of the butyric acid represented by the above general formula [III] (R 3 is a straight-chain, branched or cyclic alkyl group having one to six carbon atoms, or a substituted or unsubstituted aralkyl group).
摘要:
Compounds represented by the following general formula [I]: wherein A, R, X, Y and n are each as defined in the description; salts thereof, and insecticides/miticides characterized by containing one or more members selected from the above compounds and salts thereof as the active ingredient.