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公开(公告)号：EP2992083A4
公开(公告)日：2017-02-08
申请号：EP14791467
申请日：2014-05-01
CPC分类号： C12Q1/6869 , B01L7/52 , C12Q1/6844 , C40B20/00 , C12Q2533/101 , C12Q2565/301
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公开(公告)号：EP2232535A4
公开(公告)日：2016-04-13
申请号：EP08859647
申请日：2008-12-10
IPC分类号： H01L21/208 , B01L3/00 , H01L21/28
CPC分类号： G01N27/44743 , B01L3/0268 , B01L3/502761 , B01L3/502792 , B01L2200/0605 , B01L2200/061 , B01L2200/0647 , B01L2300/0645 , B01L2300/16 , B01L2400/0415 , B01L2400/0427
摘要： Droplet actuators for conducting droplet operations, such as droplet transport and droplet dispensing, are provided. In one embodiment, the droplet actuator may include a substrate including, droplet operations electrodes arranged for conducting droplet operations on a surface of the substrate; and reference electrodes associated with the droplet operations electrodes and extending above the surface of the substrate. Other embodiments of droplet actuators and methods of loading and using such droplet actuators are also provided.
摘要翻译： 提供用于进行液滴操作的液滴致动器，例如液滴传输和液滴分配。 在一个实施例中，液滴致动器可以包括基板，其包括布置成在基板的表面上进行液滴操作的液滴操作电极; 以及与液滴操作电极相关并在衬底的表面上方延伸的参考电极。 还提供了液滴致动器的其他实施例以及装载和使用这种液滴致动器的方法。
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公开(公告)号：EP2539450B1
公开(公告)日：2016-02-17
申请号：EP11747926.1
申请日：2011-02-22
发明人： POLLACK, Michael, G. , ECKHARDT, Allen, E. , SUDARSAN, Arjun , SRINIVASAN, Vijay , ROUSE, Jeremy , YI, Uichong , TROTTA, Nicholas , DHOPESHWARKAR, Rahul , THWAR, Prasanna , SMITH, Gregory, F. , NORTON, Scott , LINNARTZ, Peter
CPC分类号： C12N15/1075 , B01J19/0046 , C12N15/1006 , C40B40/08 , C40B50/06
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公开(公告)号：EP2188059A4
公开(公告)日：2015-05-20
申请号：EP08828680
申请日：2008-08-25
发明人： THWAR PRASANNA , ALLEN DWAYNE , PAIK PHILIP
CPC分类号： B01L3/52 , B01L3/502761 , B01L3/502792 , B01L2200/0668 , B01L2300/0864 , B01L2300/089 , B01L2400/0415 , B01L2400/0424 , B01L2400/0427
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公开(公告)号：EP2132296A4
公开(公告)日：2015-04-08
申请号：EP08745545
申请日：2008-04-10
发明人： POLLACK MICHAEL , PAMULA VAMSEE , SRINIVASAN VIJAY
CPC分类号： B01L3/502761 , B01F13/0071 , B01F13/0076 , B01L3/502792 , B01L2200/0605 , B01L2200/0647 , B01L2200/0668 , B01L2200/16 , B01L2300/0819 , B01L2300/0864 , B01L2300/0867 , B01L2300/088 , B01L2300/089 , B01L2400/0427 , B01L2400/043 , G01N27/447
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公开(公告)号：EP2729792A4
公开(公告)日：2015-03-18
申请号：EP12807397
申请日：2012-06-26
发明人： FOLEY JENNIFER , BURDE STEFAN
IPC分类号： G01N27/403 , C12Q1/68 , G01N33/48 , G01N35/00
CPC分类号： C12Q1/703 , B01L3/502784 , B01L3/502792 , B01L7/525 , B01L2200/0678 , B01L2200/16 , B01L2300/0816 , B01L2400/0427 , C12Q1/6806 , C12Q2523/308 , C12Q2527/125 , C12Q2531/113 , C12Q2563/159 , C12Q2565/607
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公开(公告)号：EP2118303B1
公开(公告)日：2014-11-19
申请号：EP08743682.0
申请日：2008-03-05
发明人： ECKHARDT, Allen E.
IPC分类号： C12Q1/00
CPC分类号： C12Q1/28 , C12Q1/005 , C12Q1/006 , G01N2333/904 , Y10T436/118339 , Y10T436/14 , Y10T436/141111 , Y10T436/142222 , Y10T436/143333 , Y10T436/144444 , Y10T436/145555 , Y10T436/146666 , Y10T436/147777 , Y10T436/148888 , Y10T436/206664
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公开(公告)号：EP2729792A2
公开(公告)日：2014-05-14
申请号：EP12807397.0
申请日：2012-06-26
发明人： FOLEY, Jennifer , BURDE, Stefan
IPC分类号： G01N27/403 , G01N33/48 , C12Q1/68 , G01N35/00
CPC分类号： C12Q1/703 , B01L3/502784 , B01L3/502792 , B01L7/525 , B01L2200/0678 , B01L2200/16 , B01L2300/0816 , B01L2400/0427 , C12Q1/6806 , C12Q2523/308 , C12Q2527/125 , C12Q2531/113 , C12Q2563/159 , C12Q2565/607
摘要： A method of providing a droplet comprising one or more reagents, the method comprising, depositing a first aqueous droplet comprising the one or more reagents on a surface; drying the droplet to yield a dried composition on the surface comprising the one or more reagents; covering the dried composition with oil; and causing a second aqueous droplet in the oil to contact the dried composition and thereby resuspend one or more reagents.
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公开(公告)号：EP2705374A2
公开(公告)日：2014-03-12
申请号：EP12779928.6
申请日：2012-05-01
发明人： BORT, Donovan , GRAHAM, Carrie , PAMULA, Vamsee , POLLACK, Michael , SISTA, Ramakrishna , SRINIVASAN, Vijay
CPC分类号： G01N27/44791 , B01F1/0027 , B01F13/0071 , B01F13/0076 , B01F2001/0055 , B01F2215/0037 , B01L3/502761 , B01L3/502792 , B01L2200/0605 , B01L2200/0668 , B01L2200/10 , B01L2200/16 , B01L2300/0816 , B01L2300/0867 , B01L2300/089 , B01L2400/0406 , B01L2400/0418 , B01L2400/0427 , B01L2400/043 , B01L2400/0487 , B81B1/004
摘要： A droplet actuator (110) comprising: one or more substrates (114, 116) arranged to form a droplet operations gap, the droplet operations gap comprising a region of gap height transition in which the gap height of the droplet operations gap transitions from a first gap height to a second gap height; and electrodes associated with the one or more substrates arranged for conducting droplet operations, the electrodes comprising a transition electrode which traverses the region of gap height transition. The electrodes may comprise electrowetting electrodes. The transition electrode may be flanked by first and second sets of electrodes having first and second footprint areas. The first footprint area may be greater than the second footprint area. The first set of electrodes may be arranged in a region of greater gap height and the second set of electrodes may be arranged in the region of lesser gap height.
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90.发明公开Droplet actuator devices and methods employing magnetic beads 有权Tröpfchenaktuatorvorrichtungen和方法用磁珠
公开(公告)号：EP2570811A3
公开(公告)日：2013-12-11
申请号：EP12191029.3
申请日：2008-02-11
发明人： Sista, Ramakrishna , Pamula, Vamsee K. , Srinivasan, Vijay , Eckhardt, Allen E. , Pollack, Michael G.
IPC分类号： G01N33/543 , B01L3/00
CPC分类号： G01N33/54326 , B01L3/502715 , B01L3/50273 , B01L3/502761 , B01L3/502784 , B01L2200/025 , B01L2200/028 , B01L2200/0647 , B01L2200/0673 , B01L2200/141 , B01L2300/0816 , B01L2300/0864 , B01L2300/0867 , B01L2400/0427 , B01L2400/043 , C12M25/01 , C12M25/16 , G01N27/44717 , G01N27/44786 , G01N33/54386 , G01N35/0098 , G01N2035/1046
摘要： A droplet actuator device (600) comprises: an array of electrodes (622) on a substrate (614) configured for conducting one or more droplet operations; a magnet (638) that exerts a magnetic field on a droplet (634) positioned on a first set of one or more of the electrodes (622); and a magnetic shield (642) that shields a droplet (634) positioned on a second set of one or more of the electrodes (622) from the magnetic field. A method of conducting a droplet operation using the device comprises: positioning a first droplet (634) comprising one or more magnetically responsive beads on one or more electrodes (622) from the first set, so that the beads are attracted by the magnetic field; positioning a second droplet comprising one or more magnetically responsive beads on one or more electrodes from the second set, so that the beads are not attracted by the magnetic field; and conducting a droplet operation on the first droplet and/or the second droplet.
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