IMPRINTED POLMYER FOR BINDING ORGANIC MOLECULES OR METAL IONS
    1.
    发明公开
    IMPRINTED POLMYER FOR BINDING ORGANIC MOLECULES OR METAL IONS 审中-公开
    压花聚合物的标准结合有机分子或金属离子

    公开(公告)号:EP1761601A4

    公开(公告)日:2008-01-23

    申请号:EP05757520

    申请日:2005-06-29

    Inventor: PETCU MIRUNA

    Abstract: The invention relates to an imprinted polymer imprinted with an organic molecule or a metal ion wherein the matrix of the polymer has been prepared from one or more monomers including bilirubin or an analogue thereof. The imprinted polymers may be prepared by polymerising one or more monomers including bilirubin or an analogue or derivative thereof in the presence of the molecule or metal ion to be imprinted or an analogue or derivative thereof, and subsequently at least partly removing the molecule or ion to be imprinted or its analogue or derivative. The polymers may be used in a method for detection and/or assay of the imprinting molecule or metal ion.

    KINETIC ASSAY
    2.
    发明公开
    KINETIC ASSAY 审中-公开
    动物测定

    公开(公告)号:EP1404717A4

    公开(公告)日:2006-03-08

    申请号:EP02738989

    申请日:2002-05-14

    CPC classification number: G01N33/54393 C07J33/00 C07J43/00

    Abstract: A hapten-linker-large group conjugate for use in a rapid assay, wherein the assay is kinetic-based not approaching equilibrium, the hapten-linker-large group conjugate being of the general formula: X - W - Y - Zwherein:X is a hapten;W is an optional thioether or ether group;Y is a linker of 10 or more atoms in length; andZ is a large group of sufficient size to provide steric hindrance with respect to the binding of X to a ligand in the absence of Y.Also provided are processes for the production of the conjugates, assay methods and kits. The assays of the invention utilising conjugates of the invention [(5)-OVA] provide a better sensitivity than the same assays with conjugates with shorter linkers [(2)-OVA and 3-OVA].

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