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1.发明授权9-SUBSTITUTED-8-OXO-ADENINE COMPOUNDS AS TOLL-LIKE RECEPTOR (TLR7 ) MODULATORS 有权9取代-8- OXOADENINVERBINDUNGEN Toll样受体的调节剂（TLR7）
公开(公告)号：EP2132209B8
公开(公告)日：2014-04-16
申请号：EP08718797.7
申请日：2008-03-19
IPC分类号： C07D473/18 , A61K31/522 , A61P37/00
CPC分类号： C07D473/18
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2.发明授权9-SUBSTITUTED-8-OXO-ADENINE COMPOUNDS AS TOLL-LIKE RECEPTOR (TLR7 ) MODULATORS 有权作为TOLL样受体（TLR7）调节剂的9-取代-8-氧杂 - 腺嘌呤化合物
公开(公告)号：EP2132209B1
公开(公告)日：2014-02-12
申请号：EP08718797.7
申请日：2008-03-19
IPC分类号： C07D473/18 , A61K31/522 , A61P37/00
CPC分类号： C07D473/18
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公开(公告)号：EP1636175B1
公开(公告)日：2008-10-15
申请号：EP04726045.0
申请日：2004-04-06
申请人： AstraZeneca AB
IPC分类号： C07C317/22 , C07C59/48 , A61K31/10 , A61K31/192
CPC分类号： C07C59/70 , C07C255/54 , C07C317/22
摘要： The invention relates to substituted phenoxyacetic acids (I) as useful pharmaceutical compounds for treating respiratory disorders, pharmaceutical compositions containing them, and processes for their preparation.
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4.发明公开MODULATORS OF CRTH2 REZEPTOR ACTIVITY FOR THE TREATMENT OF PROSTAGLANDIN D2 MEDIATED DISEASES 审中-公开活动CRTH2受体的用于治疗由前列腺素D2介导的疾病调节剂
公开(公告)号：EP1799658A2
公开(公告)日：2007-06-27
申请号：EP05787334.1
申请日：2005-10-03
申请人： AstraZeneca AB
IPC分类号： C07D261/08 , C07D213/65 , C07D333/16 , C07D333/38 , C07D333/28 , C07D333/22 , C07D307/42 , C07D231/12 , C07D213/73 , C07D295/18 , C07D209/08 , C07C57/30
CPC分类号： C07D213/73 , C07C57/58 , C07C57/60 , C07D209/08 , C07D213/65 , C07D231/12 , C07D261/08 , C07D295/192 , C07D307/42 , C07D333/16 , C07D333/22 , C07D333/28 , C07D333/38
摘要： The invention relates to substituted acids as useful pharmaceutical compounds for treating respiratory disorders as asthma, pharmaceutical compositions containing them, and processes for their preparation.
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公开(公告)号：EP1636175A1
公开(公告)日：2006-03-22
申请号：EP04726045.0
申请日：2004-04-06
申请人： AstraZeneca AB
IPC分类号： C07C317/22 , C07C59/48 , A61K31/10 , A61K31/192
CPC分类号： C07C59/70 , C07C255/54 , C07C317/22
摘要： The invention relates to substituted phenoxyacetic acids (I) as useful pharmaceutical compounds for treating respiratory disorders, pharmaceutical compositions containing them, and processes for their preparation.
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6.发明授权
公开(公告)号：EP1611091B1
公开(公告)日：2014-10-29
申请号：EP04726044.3
申请日：2004-04-06
申请人： AstraZeneca AB
发明人： BONNERT, Roger , BROUGH, Stephen , DAVIS, Andrew , LUKER, Timothy , MCINALLY, Thomas , MILLICHIP, Ian , PAIRAUDEAU, Garry , PATEL, Anil , MOHAMMED, Rukhsana , THOM, Stephen
IPC分类号： C07C65/24 , C07D213/72 , C07C255/55 , C07D215/12 , C07C271/28 , C07C275/32 , C07D317/54 , C07C317/22 , C07C317/28 , C07C59/48
CPC分类号： C07C59/68 , C07C59/70 , C07C65/24 , C07C69/94 , C07C205/35 , C07C205/37 , C07C217/80 , C07C235/42 , C07C255/55 , C07C271/28 , C07C275/32 , C07C311/29 , C07C317/22 , C07C323/18 , C07C2601/02 , C07D205/04 , C07D207/02 , C07D213/61 , C07D213/72 , C07D215/12 , C07D233/52 , C07D239/26 , C07D239/34 , C07D239/42 , C07D277/52 , C07D285/10 , C07D295/192 , C07D295/26 , C07D307/80 , C07D317/54 , C07D333/56 , C07D403/04 , C07D417/04
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7.发明公开NOVEL PYRIMIDINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF CANCER AND FURTHER DISEASES 有权新的嘧啶衍生物及其用途是治疗癌症和其他疾病的治疗
公开(公告)号：EP2432768A1
公开(公告)日：2012-03-28
申请号：EP10721195.5
申请日：2010-05-20
IPC分类号： C07D239/49 , C07D401/12 , C07D403/12 , C07D413/12 , A61K31/505 , A61K31/5377 , A61P35/00
CPC分类号： C07D413/12 , C07D239/48 , C07D239/49
摘要： The invention concerns compounds of Formula (I): wherein L
1 , R
1 , R
2 , R
3 , R
4 and X are as defined in the description. The present invention also relates to processes for the preparation of such compounds, pharmaceutical compositions containing them and their use in the treatment of disease, for example cancer.-
8.发明授权PHENOXYACETIC ACID DERIVATIVES USEFUL FOR TREATING RESPIRATORY DISEASES 有权呼吸系统疾病SUITABLE苯氧基乙酸衍生物的治疗
公开(公告)号：EP1817282B1
公开(公告)日：2011-07-20
申请号：EP05807437.8
申请日：2005-11-22
申请人： AstraZeneca AB
发明人： BONNERT, Roger Victor , ALCARAZ, Lilian , MOHAMMED, Rukhsana Tasneem , COOK, Anthony Ronald , THOM, Stephen , LUKER, Timothy Jon
IPC分类号： C07D207/48 , C07C59/72 , C07D333/24 , C07D213/34 , C07D213/56 , C07D241/08 , A61K31/495 , A61P11/00
CPC分类号： C07D333/24 , C07D207/48 , C07D213/34 , C07D213/56 , C07D241/08
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9.发明公开PHENOXYACETIC ACID DERIVATIVES USEFUL FOR TREATING RESPIRATORY DISEASES 有权呼吸系统疾病SUITABLE苯氧基乙酸衍生物的治疗
公开(公告)号：EP1817282A1
公开(公告)日：2007-08-15
申请号：EP05807437.8
申请日：2005-11-22
申请人： AstraZeneca AB
发明人： BONNERT, Roger Victor , ALCARAZ, Lilian , MOHAMMED, Rukhsana Tasneem , COOK, Anthony Ronald , THOM, Stephen , LUKER, Timothy Jon
IPC分类号： C07D207/48 , C07C59/72 , C07D333/24 , C07D213/34 , C07D213/56 , C07D241/08 , A61K31/495 , A61P11/00
CPC分类号： C07D333/24 , C07D207/48 , C07D213/34 , C07D213/56 , C07D241/08
摘要： The invention relates to substituted phenoxyacetic acids as useful pharmaceutical compounds for treating respiratory disorders, pharmaceutical compositions containing them, and processes for their preparation.Formula (I)
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10.发明授权2,4-Dithi(oxo)-pyridin-5-yl compounds bearing a tricyclic substituent useful as P2 purinoceptor antagonists 失效三环取代的2,4- Dithi（氧代） - 嘧啶-5-基化合物作为P2嘌呤拮抗剂
公开(公告)号：EP0996617B1
公开(公告)日：2002-01-09
申请号：EP98934002.1
申请日：1998-06-25
申请人： AstraZeneca AB
发明人： KINDON, Nicholas , MEGHANI, Premji , THOM, Stephen
IPC分类号： C07D239/46 , C07D403/04 , C07D403/06 , C07D403/14 , C07D401/04 , C07D401/06 , C07D413/14 , A61K31/505
CPC分类号： C07D239/54 , C07D239/557 , C07D401/06 , C07D401/14 , C07D403/04 , C07D403/14 , C07D417/14 , C07D473/32
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