COMPOSITIONS FOR BINDING AND SEPARATING OF PROTEINS
    5.
    发明公开
    COMPOSITIONS FOR BINDING AND SEPARATING OF PROTEINS 有权
    ZUSAMMENSETZUNGEN ZUR BINDUNG UND TRENNUNG VON PROTEINEN

    公开(公告)号:EP2943501A1

    公开(公告)日:2015-11-18

    申请号:EP13734148.3

    申请日:2013-05-30

    IPC分类号: C07K1/22 B01D15/38

    摘要: A composition for binding and separating proteins characterized by the general formula (II) wherein R1 is a hydrophobic group of small size, preferably hydrogen, or C1C8 straight chain or branched alkyl, or C2-C8 straight chain or branched alkenyl or alkynyl, C6-G8 aryl or aralkyl or cycloalkyl group; or alkoxy group, preferably methoxy or ethoxy group; or acyloxy group, preferably acetyloxy group; or chlorine, R2 is R1 or a hydrophobic group of small size, preferably hydrogen, or C1C8 straight chain or branched alkyl, or C2-C8 straight chain or branched alkenyl or alkynyl, C6-C8 aryl or aralkyl or cycloalkyl group; or alkoxy group, preferably methoxy- or ethoxy group; or acyloxy group, preferably acetyloxy group; or chlorine different form R1, R3 is R2 or a non-reactive group which contains straight chain, branched or cyclic structures formed by 2 - 30 covalently connected carbon, oxygen, sulfur, fluorine, chlorine, bromine or iodine atoms, symbol = represents one, two or three covalent single bonds between the Si atoms and the surface of the support, in case of one covalent bond, two of the R1- R3 groups are attached to the given Si atom; in case of two covalent bonds, one of the R1- R3 groups is attached to the given Si atom; in case of three covalent bonds, none of the groups R1 - R3 are attached to the given Si atom, A is an atom or group of atoms containing a non-bonding pair of electrons, preferably NH, NR3, S, O, L is a straight, branched or cyclic structure connecting Si atoms and the A moiety comprising 2 - 22 carbon, sulfur or nitrogen atoms covalently connected to each other, x is a number and 0 >x> 1, m is an integer and m = 0, 1 or 2.

    摘要翻译: 用于结合和分离由通式(II)表示的蛋白质的组合物,其中R1是小尺寸的疏水基团,优选氢,或C1C8直链或支链烷基或C2-C8直链或支链烯基或炔基,C6- G8芳基或芳烷基或环烷基; 或烷氧基,优选甲氧基或乙氧基; 或酰氧基,优选乙酰氧基; 或氯,R2为R1或疏水性基团,优选氢,或C1C8直链或支链烷基或C2-C8直链或支链烯基或炔基,C6-C8芳基或芳烷基或环烷基; 或烷氧基,优选甲氧基或乙氧基; 或酰氧基,优选乙酰氧基; 或氯不同的形式R1,R3是R2或非反应性基团,其包含由2-30共价连接的碳,氧,硫,氟,氯,溴或碘原子形成的直链,支链或环状结构,符号=表示一个 ,在Si原子和载体表面之间的两个或三个共价单键,在一个共价键的情况下,两个R 1 -R 3基团连接到给定的Si原子上; 在两个共价键的情况下,R 1 -R 3基团之一连接到给定的Si原子上; 在三个共价键的情况下,R1-R3基团不连接在给定的Si原子上,A是含有非键合电子对的原子或原子团,优选为NH,NR 3,S,O,L为 连接Si原子的直链,支链或环状结构和包含彼此共价连接的2-22个碳,硫或氮原子的A部分,x是数x并且0> x> 1,m是整数,m = 0, 1或2。

    VERFAHREN ZUR BESCHICHTUNG EINES BAUTEILS MIT EINER SCHICHT AUS METALLORGANISCHEM NETZWERK UND MIT EINER SCHICHT AUS METALLORGANISCHEM NETZWERK BESCHICHTETES BAUTEIL
    9.
    发明公开

    公开(公告)号:EP2729246A1

    公开(公告)日:2014-05-14

    申请号:EP12743911.5

    申请日:2012-07-04

    摘要: According to the invention, a method is provided for coating at least in areas a component with a layer of a metal-organic framework (MOF), in which the body is contacted with a solution containing at least one metal salt (MOF precursor), at least one linker, and at least one solvent. The linker in this case can effect the bonding of the MOF layer to the surface of the component and/or the structure of the MOF layer. The method is characterized in that the solution has a temperature gradient, wherein the temperature of the solution immediately at the surface of the component permits the crystallization of an MOF layer on the surface, whereas the temperature of the remaining solution prevents the formation of MOF crystals in the remaining solution. The method can be used for producing components having layers of defined chemical and/or physical properties. Furthermore, the invention comprises components which have at least in areas an MOF layer. A possible use of said components is in sorption refrigeration machines.

    摘要翻译: 。根据本发明,至少在部分区域被提供用于涂层的方法与金属 - 有机骨架(MOF),其中,所述体与含有至少一种金属盐(MOF前体)的溶液接触的层的成分 至少一个左,和至少一种溶剂。 左在这种情况下可以实现MOF层的接合到组件和/或MOF层的结构的表面上。 该方法是在DASS模具溶液为特征的具有温度梯度,worin立即在部件的表面上的溶液的温度允许的表面上的MOF层的结晶体,而剩余的溶液的温度,防止MOF晶体的形成 在剩余溶液中。 该方法可用于生产具有确定的化学和/或物理性质的层的部件。 进一步,本发明包括其中在MOF层的区域至少有组分。 一种可能的使用中,所述部件之一是在吸收式制冷机。