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公开(公告)号：EP1124791B1
公开(公告)日：2005-01-12
申请号：EP99952694.0
申请日：1999-11-03
发明人： MOLONEY, Mark Gerard, Dept. of Chemistry , EBENEZER, Warren, Dept. of Chemistry , AWENAT, Karim, Dept. of Chemistry
IPC分类号： C07C245/14 , C08J7/12
CPC分类号： C08J7/12 , C07C245/14 , C07C245/20 , D06P1/008 , D06P5/22
摘要： A process for the surface functionalisation of a polymeric substrate, which process comprises: a) contacting the substrate with a diarylcarbene precursor, b) generating a carbene reactive intermediate from the diarylcarbene precursor so that it reacts with the substrate to functionalise the surface, and c) further functionalising the activated substrate obtained in step (b).
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公开(公告)号：EP1273568A3
公开(公告)日：2003-08-06
申请号：EP02014698.1
申请日：2002-07-03
IPC分类号： C07C245/14 , C07D295/12 , C07C271/20 , C07C281/02 , D21H25/18
CPC分类号： C07D295/13 , C07C245/14 , C07C271/20 , C07C281/02 , D21H25/18
摘要： Novel diazo derivatives useful for the deacidification of paper material and the process for their preparation comprising three steps starting from an amine and ethyl chlorocarbonate, are described.
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3.发明公开Photosensitive material and process for forming pattern using the same 失效Photoempfindliches材料和Verfahren zur Herstellung von Strukturen damit。
公开(公告)号：EP0319325A2
公开(公告)日：1989-06-07
申请号：EP88311463.9
申请日：1988-12-02
IPC分类号： G03F7/10
CPC分类号： C07D295/26 , C07C245/14 , C07C309/88 , G03F7/0163
摘要： A photosensitive composition comprising a resin such as an alkali-soluble resin and a photosensitive compound such as a novel 3-diazo-2,4-dione derivative, a novel Meldrum's acid derivative, or the like is effective for forming a fine pattern using deep UV light of less than about 300 nm.
摘要翻译： 包含诸如碱溶性树脂的树脂和新颖的3-重氮基-2,4-二酮衍生物等感光性化合物，新颖的Meldrum's酸衍生物等的感光性组合物可以有效地形成使用深度的精细图案 小于约300nm的UV光。
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公开(公告)号：EP3315491A1
公开(公告)日：2018-05-02
申请号：EP17197122.9
申请日：2017-10-18
IPC分类号： C07D231/08 , C07D231/12 , C07D231/14 , C07D487/04 , C07C245/14 , C07D213/26 , C07C17/32 , C07C22/08
CPC分类号： C07C249/00 , C07C17/32 , C07C22/08 , C07C245/14 , C07C2601/02 , C07C2603/08 , C07D213/26 , C07D231/08 , C07D231/12 , C07D231/14 , C07D487/04
摘要： Die Erfindung betrifft ein Verfahren zur Herstellung eines fluorierten Diazoalkans, wobei es sich bei dem Verfahren um ein kontinuierliches Verfahren handelt und ein β,β-Difluoralkylamin mit einem organischen Nitrit in einem Reaktor umgesetzt wird, wobei das β,β-Difluoralkylamin und das organische Nitrit in getrennten Gefäßen vorgelegt werden, sowie die Verwendung des Verfahren zur Herstellung einer fluoralkyl-substituierten Verbindung.
摘要翻译： 本发明涉及一种方法，用于生产氟化重氮烷，其特征在于，它是在该过程是连续的过程和一个β，β-Difluoralkylamin与在反应器中的有机亚硝酸酯，其中，所述β，β-Difluoralkylamin和有机亚硝酸酯反应 呈现在分开的容器中，以及使用生产氟代烷基取代的化合物的方法。
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公开(公告)号：EP2635548B8
公开(公告)日：2015-02-18
申请号：EP11778584.0
申请日：2011-11-01
发明人： REINTJENS, Rafael, Wilhelmus, Elisabeth, Ghislain , DIELEMANS, Hubertus, Johannes, Adrianus , THATHAGAR, Mehul , KONINGS, Jeroen, Hubertina, Gerardus , POECHLAUER, Peter
IPC分类号： C07C67/00 , C07C69/78 , C07C245/14 , C07C245/16
CPC分类号： C07C245/16 , C07C67/00 , C07C245/14 , C07D231/06 , C07C69/78
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6.发明公开
公开(公告)号：EP1091934A2
公开(公告)日：2001-04-18
申请号：EP99932068.2
申请日：1999-06-29
IPC分类号： C07C323/25
CPC分类号： C07C323/25 , C07C233/31 , C07C245/14 , C07C271/18 , C07C271/22 , C07C323/22 , C07C323/48 , C07C323/52 , C07C323/58 , C07C323/59 , C07C323/60 , C07C2603/18
摘要： Novel alkyl ketone compounds having potent cytotoxic activity are described as antitumor agents and are particularly effective against leukemia and breast tumor cells. The compounds of the invention have formula (I), wherein R1-R4, X and p have the meanings given in the description.
摘要翻译： 具有强力细胞毒活性的新型烷基酮化合物被描述为抗肿瘤剂，对白血病和乳腺肿瘤细胞特别有效。 本发明的化合物具有式（I），其中R 1 -R 4，X和p具有在说明书中给出的含义。
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公开(公告)号：EP0647612A1
公开(公告)日：1995-04-12
申请号：EP94115265.4
申请日：1994-09-28
IPC分类号： C07C205/38 , C07C317/22 , C07D231/20
CPC分类号： C07D213/643 , A01N37/38 , A01N37/40 , A01N39/02 , A01N39/04 , A01N43/40 , A01N43/56 , C07C43/29 , C07C205/37 , C07C205/38 , C07C217/92 , C07C235/20 , C07C245/14 , C07C317/22 , C07C323/20 , C07D231/22
摘要： There are provided aryloxybenzene compounds of formula I
Further provided are compositions and methods comprising those compounds for the control of undesirable plant species.摘要翻译： 提供式I的芳氧基苯化合物
进一步提供包含用于控制不期望的植物物种的那些化合物的组合物和方法。 -
公开(公告)号：EP0910561B1
公开(公告)日：2004-04-07
申请号：EP97931457.2
申请日：1997-06-26
IPC分类号： C07C259/06 , C07C45/45 , C07C47/21 , C07C49/227 , C07C59/42 , C07C69/716 , C07C69/738 , C07C233/08 , C07C233/09 , C07C235/28 , C07C235/76 , C07C243/30 , C07C245/14 , A61K31/12 , A61K31/15 , A61K31/16 , A61K31/23 , A61K31/655
CPC分类号： A61K31/08 , A61K31/11 , A61K31/12 , A61K31/121 , A61K31/15 , A61K31/16 , A61K31/201 , A61K31/23 , A61K31/231 , A61K31/655 , C07C45/45 , C07C45/63 , C07C47/21 , C07C49/227 , C07C59/42 , C07C69/716 , C07C69/738 , C07C233/09 , C07C235/28 , C07C235/76 , C07C243/30 , C07C245/14 , C07C259/06
摘要： Inhibitors of oleamide hydrolase, responsible for the hydrolysis of an endogenous sleep-inducing lipid (1, cis-9-octadecenamide) were designed and synthesized. The most potent inhibitors possess an electrophilic carbonyl group capable of reversibly forming a (thio) hemiacetal or (thio) hemiketal to mimic the transition state of a serine or cysteine protease catalyzed reaction. In particular, the tight binding α-keto ethyl ester 8 (1.4 nM) and the trifluoromethyl ketone inhibitor 12 (1.2 nM) were found to have exceptional inhibitory activity. In addition to the inhibitory activity, some of the inhibitors displayed agonist activity which resulted in the induction of sleep in laboratory animals.
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9.发明公开REACTIFS DE MARQUAGE, PROCEDES DE SYNTHESE DE TELS REACTIFS ET PROCEDES DE DETECTION DE MOLECULES BIOLOGIQUES 有权标记试剂，处理此试剂用于检测生物分子的合成和方法
公开(公告)号：EP1383732A1
公开(公告)日：2004-01-28
申请号：EP02740788.1
申请日：2002-05-03
申请人： BIO MERIEUX , UNIVERSITE JOSEPH FOURIER (GRENOBLE 1) , CENTRE NATIONAL DELA RECHERCHE SCIENTIFIQUE (CNRS)
发明人： BOURGET, Cécile , LHOMME, Jean , LAAYOUN, Ali , KOTERA, Mitsuharu , TREVISIOL, Emmanuelle , MENOU, Lionel , BERNAL MENDEZ, Eloy
IPC分类号： C07C245/14 , C07C245/18 , C07D209/14 , C07D495/04 , C07D311/82 , C12Q1/68
CPC分类号： C07D209/08 , C07C245/14 , C07C245/18 , C07D311/90 , C07D495/04
摘要： The invention concerns a temperature-stable labelling reagent of formula (I), wherein: R1 represents H or an alkyl, aryl or substituted aryl group; R2 represents a detectable marker or at least two detectable markers linked together by at least a multimeric structure; L is a linking arm comprising a linear catemer concatenation of at least two covalent bonds; and n is an integer equal to 0 or 1; R?3 and R4¿ represent, independently of each other: H, NO¿2?, Cl, Br, F, I, R?2-(L)¿n-Y-X-, OR, SR, NR2, R, NHCOR, CONHR, COOR with R = alkyl or aryl, A is a linking arm comprising at least a double bond enabling the conjugation of the diazo function with the aromatic cycle; and u is a whole number between 0 and 2, preferably between 0 and 1; and -Y-X- represents -CONH-, -NHCO-, -CH2O-, -CH2S-. The invention also concerns a method for the synthesis of said markers and uses for labelling biological molecules, in particular nucleic acids, with a labelling reagent bearing the diazomethyl function. The invention is particularly applicable in the field of diagnosis.
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公开(公告)号：EP0685459B1
公开(公告)日：1998-10-07
申请号：EP95902975.2
申请日：1994-12-16
IPC分类号： C07C245/16 , C07B61/00 , B01J31/02 , B01J31/26 , C07C245/14
CPC分类号： C07C245/14
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