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1.发明公开LACTIC ACID-PRODUCING YEAST CELLS HAVING NONFUNCTIONAL L-OR D-LACTATE: FERRICYTOCHROME C OXIDOREDUCTASE GENE 有权乳酸生产具有非功能性或L的D- LACTAT酵母细胞：高铁-C氧化还原酶基因：
公开(公告)号：EP1960516A2
公开(公告)日：2008-08-27
申请号：EP06850558.5
申请日：2006-11-17
申请人： NatureWorks LLC
发明人： MILLER, Matthew , SUOMINEN, Pirkko , ARISTIDOU, Aristos , HAUSE, Benjamin, Matthew , VAN HOEK, Pim , DUNDON, Catherine, Asleson
CPC分类号： C12N9/0006 , C12P7/56 , C12Y101/02003
摘要： Yeast cells having an exogenous lactate dehydrogenase gene ae modified by reducing L- or D-lactate:ferricytochrome c oxidoreductase activity in the cell. This leads to reduced consumption of lactate by the cell and can increase overall lactate yields in a fermentation process. Cells having the reduced L- or D- lactate:ferricytochrome c oxidoreductase activity can be screened for by resistance to organic acids such as lactic or glycolic acid.
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2.发明授权LACTIC ACID-PRODUCING YEAST CELLS HAVING NONFUNCTIONAL L-OR D-LACTATE: FERRICYTOCHROME C OXIDOREDUCTASE GENE 有权乳酸生产具有非功能性或L的D- LACTAT酵母细胞：高铁-C氧化还原酶基因：
公开(公告)号：EP1960516B1
公开(公告)日：2012-12-26
申请号：EP06850558.5
申请日：2006-11-17
发明人： MILLER, Matthew , SUOMINEN, Pirkko , ARISTIDOU, Aristos , HAUSE, Benjamin, Matthew , VAN HOEK, Pim , DUNDON, Catherine, Asleson
CPC分类号： C12N9/0006 , C12P7/56 , C12Y101/02003
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3.发明公开Gene knockout mesophilic and thermophilic organisms, and methods of use thereof 审中-公开嗜温和嗜热生物的基因敲除和使用它们的方法
公开(公告)号：EP2511286A3
公开(公告)日：2012-11-28
申请号：EP12164672.3
申请日：2008-05-09
申请人： Mascoma Corporation
CPC分类号： C12P7/10 , C12N9/0006 , C12N9/1029 , C12N9/1205 , C12N9/1217 , C12N9/88 , C12N9/90 , C12N9/92 , C12N15/74 , C12P7/065 , C12P2203/00 , C12Y101/01002 , C12Y101/01027 , C12Y101/02003 , C12Y203/01008 , C12Y207/01017 , C12Y207/02001 , C12Y503/01005 , Y02E50/16 , Y02E50/17
摘要： One aspect of the invention relates to a genetically modified thermophilic or mesophilic microorganism, wherein a first native gene is partially, substantially, or completely deleted, silenced, inactivated, or down-regulated, which first native gene encodes a first native enzyme involved in the metabolic production of an organic acid or a salt thereof, thereby increasing the native ability of said thermophilic or mesophilic microorganism to produce ethanol as a fermentation product. In certain embodiments, the aforementioned microorganism further comprises a first non-native gene, which first non- native gene encodes a first non-native enzyme involved in the metabolic production of ethanol.; Another aspect of the invention relates to a process for converting lignocellulosic biomass to ethanol, comprising contacting lignocellulosic biomass with a genetically modified thermophilic or mesophilic microorganism.
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4.发明授权Bacterial cells exhibiting formate dehydrogenase activity for the manufacture of suc-cinic acid 有权细菌细胞与Formatdehydrogenaseaktivität用于生产琥珀酸的
公开(公告)号：EP2204443B1
公开(公告)日：2015-11-25
申请号：EP09178050.2
申请日：2009-12-04
申请人： BASF SE
CPC分类号： C12N9/0006 , C12N9/0008 , C12N9/1029 , C12P7/46 , C12Y101/02003 , C12Y102/01002 , C12Y203/01054
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5.发明公开Gene knockout mesophilic and thermophilic organisms, and methods of use thereof 审中-公开嗜温和嗜热生物的基因敲除和使用它们的方法
公开(公告)号：EP2511284A2
公开(公告)日：2012-10-17
申请号：EP12164670.7
申请日：2008-05-09
申请人： Mascoma Corporation
CPC分类号： C12P7/10 , C12N9/0006 , C12N9/1029 , C12N9/1205 , C12N9/1217 , C12N9/88 , C12N9/90 , C12N9/92 , C12N15/74 , C12P7/065 , C12P2203/00 , C12Y101/01002 , C12Y101/01027 , C12Y101/02003 , C12Y203/01008 , C12Y207/01017 , C12Y207/02001 , C12Y503/01005 , Y02E50/16 , Y02E50/17
摘要： One aspect of the invention relates to a genetically modified thermophilic or mesophilic microorganism, wherein a first native gene is partially, substantially, or completely deleted, silenced, inactivated, or down-regulated, which first native gene encodes a first native enzyme involved in the metabolic production of an organic acid or a salt thereof, thereby increasing the native ability of said thermophilic or mesophilic microorganism to produce ethanol as a fermentation product. In certain embodiments, the aforementioned microorganism further comprises a first non-native gene, which first non- native gene encodes a first non-native enzyme involved in the metabolic production of ethanol.; Another aspect of the invention relates to a process for converting lignocellulosic biomass to ethanol, comprising contacting lignocellulosic biomass with a genetically modified thermophilic or mesophilic microorganism.
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6.发明公开Bacterial cells exhibiting formate dehydrogenase activity for the manufacture of suc-cinic acid 有权Bakterienzellen mitFormathydrogenaseaktivitätzur Herstellung vonBernsteinsäure
公开(公告)号：EP2204443A1
公开(公告)日：2010-07-07
申请号：EP09178050.2
申请日：2009-12-04
申请人： BASF SE
CPC分类号： C12N9/0006 , C12N9/0008 , C12N9/1029 , C12P7/46 , C12Y101/02003 , C12Y102/01002 , C12Y203/01054
摘要： The present invention relates to a bacterial cell of the genus Pastorella (Pasteurella) comprising a heterologous polypeptide having formate dehydrogenase activity. Moreover, the present invention also relates to a method of manufacturing succinic acid and the use of the bacterial cell for the manufacture of succinig acid.
摘要翻译： 本发明涉及一种含有甲酸脱氢酶活性的异源多肽的Pastorella（巴斯德氏菌属）的细菌细胞。 此外，本发明还涉及制备琥珀酸的方法以及细菌细胞用于制备琥珀酸的用途。
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7.发明公开GENE KNOCKOUT MESOPHILIC AND THERMOPHILIC ORGANISMS, AND METHODS OF USE THEREOF 审中-公开MESOSPHILE和THERMO AUDIOPHILE根淘汰赛机制和方法应用
公开(公告)号：EP2064225A2
公开(公告)日：2009-06-03
申请号：EP08769395.8
申请日：2008-05-09
申请人： Mascoma Corporation
CPC分类号： C12P7/10 , C12N9/0006 , C12N9/1029 , C12N9/1205 , C12N9/1217 , C12N9/88 , C12N9/90 , C12N9/92 , C12N15/74 , C12P7/065 , C12P2203/00 , C12Y101/01002 , C12Y101/01027 , C12Y101/02003 , C12Y203/01008 , C12Y207/01017 , C12Y207/02001 , C12Y503/01005 , Y02E50/16 , Y02E50/17
摘要： One aspect of the invention relates to a genetically modified thermophilic or mesophilic microorganism, wherein a first native gene is partially, substantially, or completely deleted, silenced, inactivated, or down-regulated, which first native gene encodes a first native enzyme involved in the metabolic production of an organic acid or a salt thereof, thereby increasing the native ability of said thermophilic or mesophilic microorganism to produce ethanol as a fermentation product. In certain embodiments, the aforementioned microorganism further comprises a first non-native gene, which first non- native gene encodes a first non-native enzyme involved in the metabolic production of ethanol. Another aspect of the invention relates to a process for converting lignocellulosic biomass to ethanol, comprising contacting lignocellulosic biomass with a genetically modified thermophilic or mesophilic microorganism.
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公开(公告)号：EP1077609B1
公开(公告)日：2008-07-09
申请号：EP99923017.0
申请日：1999-05-13
申请人： Novozymes, Inc. , Novozymes A/S
发明人： XU, Feng , WAGNER, Peter
CPC分类号： C12Y101/02003 , A21D2/267 , A21D8/042 , C12Y101/99011 , C12Y101/99018
摘要： The present invention relates to methods for preparing a dough, comprising incorporating into the dough a composition comprising an effective amount of one or more dehydrogenases which improve one or more properties of the dough or a baked product obtained from the dough. The present invention also relates to methods for preparing a baked product. The present invention also relates to compositions comprising an effective amount of one or more dehydrogenases for improving one or more properties of a dough and/or a baked product obtained from the dough. The present invention further relates to doughs or baked products and to pre-mixes for a dough.
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9.发明公开ACID-TOLERANT YEAST CELL, METHOD OF PRODUCING ORGANIC ACID USING THE SAME, AND METHOD OF PRODUCING THE YEAST CELL 有权耐酸酵母细胞，用于生产有机的酸形成使用和制造方法酵母
公开(公告)号：EP3124604A3
公开(公告)日：2017-04-05
申请号：EP16180739.1
申请日：2016-07-22
发明人： CHU, Hunsu , CHO, Hwayoung , PARK, Jinhwan , YANG, Dongsik , RHEE, Hongsoon , CHO, Kwangmyung
CPC分类号： C12P7/56 , C12N9/0006 , C12N9/0036 , C12N9/0071 , C12N9/1029 , C12N9/88 , C12N15/52 , C12Y101/01008 , C12Y101/01027 , C12Y101/01028 , C12Y101/02003 , C12Y101/02004 , C12Y106/05003 , C12Y106/05009 , C12Y114/19001 , C12Y203/01022 , C12Y203/01158
摘要： Provided are an acid-tolerant yeast cell, a method of producing an organic acid by using the yeast cell, and a method of producing the yeast cell resistant to acid.
摘要翻译： 本发明提供了在酸耐受性酵母细胞，通过使用酵母细胞在有机酸的制造方法，以及制备所述酵母细胞耐强酸的方法。
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公开(公告)号：EP2511287A3
公开(公告)日：2012-11-28
申请号：EP12164673.1
申请日：2008-05-09
申请人： Mascoma Corporation
CPC分类号： C12P7/10 , C12N9/0006 , C12N9/1029 , C12N9/1205 , C12N9/1217 , C12N9/88 , C12N9/90 , C12N9/92 , C12N15/74 , C12P7/065 , C12P2203/00 , C12Y101/01002 , C12Y101/01027 , C12Y101/02003 , C12Y203/01008 , C12Y207/01017 , C12Y207/02001 , C12Y503/01005 , Y02E50/16 , Y02E50/17
摘要： One aspect of the invention relates to a genetically modified thermophilic or mesophilic microorganism, wherein a first native gene is partially, substantially, or completely deleted, silenced, inactivated, or down-regulated, which first native gene encodes a first native enzyme involved in the metabolic production of an organic acid or a salt thereof, thereby increasing the native ability of said thermophilic or mesophilic microorganism to produce ethanol as a fermentation product. In certain embodiments, the aforementioned microorganism further comprises a first non-native gene, which first non- native gene encodes a first non-native enzyme involved in the metabolic production of ethanol.; Another aspect of the invention relates to a process for converting lignocellulosic biomass to ethanol, comprising contacting lignocellulosic biomass with a genetically modified thermophilic or mesophilic microorganism.
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