公开(公告)号：EP3394593A1

公开(公告)日：2018-10-31

申请号：EP16826718.5

申请日：2016-12-20

Applicant: Dublin Institute of Technology

Inventor： LYNG, Fiona ,  MAGUIRE, Adrian ,  MEADE, Aidan ,  VEGA CARRASCAL, Isabel ,  WHITE, Lisa ,  HOWE, Orla

IPC: G01N21/00 ,  G01N33/483

CPC classification number: G01N33/4833 ,  G01N21/65 ,  G01N33/54366 ,  G01N33/574 ,  G01N2021/3595 ,  G01N2201/129 ,  G01N2800/52

Abstract: A prognostic method of analyzing a biological sample from a patient with cancer to predict their response to cancer treatment using radiotherapy, chemotherapy, hormonal therapy and/or combinations of these treatments. The prognostic method involves performing spectroscopy (such as Raman spectroscopy) on the biological sample to obtain a spectrum. The obtained spectrum is then correlated with one or more pre-classified spectra (such as by the use of principle component analysis PCA, decision trees or a neural network) to obtain a probability factor indicating the likelihood of success of cancer treatment by one of the specified modalities on the cancer patient.

公开(公告)号：EP2366101B1

公开(公告)日：2018-10-31

申请号：EP09752669.3

申请日：2009-11-11

Applicant: The Boeing Company

Inventor： GRACE, William B ,  WERNER, Gregory J ,  SHELLEY, Paul H

IPC: G01N21/3554 ,  G01N21/359 ,  G01N21/84

CPC classification number: G01N21/3554 ,  G01N21/359 ,  G01N2021/8472 ,  G01N2201/0221 ,  G01N2201/129

Abstract: A method of determining moisture content of a composite material includes providing composite material standards with moisture content, collecting infrared spectra on the composite material standards, calibrating the infrared spectra to the moisture content, providing a composite material and predicting moisture content of the composite material based on the infrared spectra and the composite material standards.

公开(公告)号：EP3385703A1

公开(公告)日：2018-10-10

申请号：EP17305412.3

申请日：2017-04-07

Applicant: GREENTROPISM

Inventor： LABORDE, Antoine ,  BOURDEAU, Aude ,  BOULANGER, Anthony

IPC: G01N21/27 ,  G01N21/31 ,  G01J3/28 ,  G01J3/42 ,  G01N33/44 ,  G01N33/10

CPC classification number: G01N21/314 ,  G01J3/28 ,  G01J3/42 ,  G01J2003/2833 ,  G01J2003/2843 ,  G01J2003/2866 ,  G01J2003/2869 ,  G01J2003/2873 ,  G01N21/274 ,  G01N21/31 ,  G01N33/10 ,  G01N2201/121 ,  G01N2201/129 ,  G01N2201/1293

Abstract: The invention relates to a characterization device (50) for characterizing a sample (S) comprising:
- a memory (MEM) storing a mesured spectrum (A s+p ) of said sample, performed through a translucent material, and a measured spectrum of the translucent material (A p ),
- a processing unit (PU) configured to:
* determine a spectral energy (E s+p ) of the measured spectrum (A s+p ) of the sample through the translucent material (A s+p ),
* estimate a coefficient ( γ̂ ) from said spectral energy (E s+p ) and,
* determine a corrected spectrum (Â s ) of the sample from the measured spectrum (A s+p ) of the sample through the translucent material and from a corrected spectrum of the translucent material (Â p ),

said corrected spectrum of the translucent material (Â p ) being determined from the measured spectrum of the translucent material (Â p ) and from the estimated coefficient ( γ̂ ).

公开(公告)号：EP2138830B1

公开(公告)日：2018-08-08

申请号：EP09251571.7

申请日：2009-06-16

Applicant: The Boeing Company

Inventor： Shelley, Paul H. ,  LeRiviere, Diane R. ,  Gross, Gwen M. ,  Werner, Gregory J.

IPC: G01N21/3563 ,  G01N21/84 ,  G01N17/00 ,  G01N21/55

CPC classification number: G01N21/3563 ,  G01N21/55 ,  G01N21/84 ,  G01N2021/8472 ,  G01N2201/0221 ,  G01N2201/129 ,  G01N2201/1293

Abstract: A method of non-destructively determining the amount of ultraviolet degradation of a surface and/or paint adhesion characteristics of the surface corresponding with UV damage including determining a physical property of a composite material/surfacing film by providing a series of composite materials/surfacing films which are subjected to increasing UV light experience to create a set of UV damage standards, collecting mid-IR spectra on those standards, performing data pre-processing and then multivariate calibration on the spectra of the composite materials/ surfacing films, and using that calibration to predict the UV damage for samples in question.

公开(公告)号：EP3282937A1

公开(公告)日：2018-02-21

申请号：EP16780499.6

申请日：2016-04-08

Applicant: Nueon Inc.

Inventor： MESSERSCHMIDT, Robert G. ,  JONES, Howland D. T.

IPC: A61B5/026 ,  G01N21/27 ,  G01N21/35

CPC classification number: G01N33/492 ,  A61B5/0082 ,  A61B5/021 ,  A61B5/02108 ,  A61B5/14546 ,  A61B5/1455 ,  G01J3/42 ,  G01N21/35 ,  G01N21/552 ,  G01N33/80 ,  G01N2201/129 ,  G01N2333/805 ,  G01N2800/32 ,  G01N2800/50 ,  G01N2800/52 ,  G16H10/40

Abstract: Biomarkers of high blood pressure are measured to identify high blood pressure of the subject based on one or more biomarkers. In many embodiments, the response of the biomarker to blood pressure occurs over the course of at least an hour, such that the high blood pressure identification is based on a cumulative effect of physiology of the subject over a period of time. The methods and apparatus of identifying high blood pressure with biomarkers have the advantage of providing improved treatment of the subject, as the identified biomarker can be related to an effect of the high blood pressure on the subject, such as a biomarker corresponding to central blood pressure. The sample can be subjected to increases in one or more of pressure or temperatures, and changes in the blood sample measured over time.

公开(公告)号：EP3265785A1

公开(公告)日：2018-01-10

申请号：EP16860766.1

申请日：2016-10-27

Applicant: Cedars-Sinai Medical Center

Inventor： BLACK, Keith L. ,  BAKER, Michael ,  JONES, Howland ,  BUTTE, Pramod

IPC: G01N21/64 ,  A61B5/00 ,  G01J3/02 ,  G01J3/28 ,  G01J3/44

CPC classification number: A61B5/0071 ,  A61B5/00 ,  A61B5/0075 ,  A61B5/0091 ,  A61B5/08 ,  A61B5/4064 ,  A61B5/4255 ,  A61B5/441 ,  A61B5/7267 ,  A61B10/02 ,  A61B2017/00057 ,  A61B2576/026 ,  G01N21/6402 ,  G01N21/6408 ,  G01N2201/06113 ,  G01N2201/129 ,  G06K9/6267 ,  G06T7/0012 ,  G06T2207/10064 ,  G06T2207/30016 ,  G06T2207/30028 ,  G06T2207/30061 ,  G06T2207/30068 ,  G06T2207/30088

Abstract: Described herein are methods and systems for analyzing a sample by applying time resolved laser induced fluorescence spectroscopy to the sample to measure lifetime time decay profile data relating to the sample, and applying multivariate analysis to process the data so as to classify a sample as, for example, normal or abnormal. The sample may be cells, fluid or tissue from any organ. The sample may be in vitro or in vivo. The data may be obtained in situ or in vitro.

公开(公告)号：EP3238934A1

公开(公告)日：2017-11-01

申请号：EP16166988.2

申请日：2016-04-26

Applicant: SWISS KRONO Tec AG

Inventor： BRAUN, Roger ,  DENK, Andre ,  KALWA, Norbert, Dr.

IPC: B32B21/00 ,  B32B29/00 ,  G01N21/35 ,  G01N21/3563 ,  G01N21/84 ,  G01N35/00 ,  G01N21/359

CPC classification number: G01N21/8422 ,  B32B21/00 ,  B32B29/00 ,  G01N21/3563 ,  G01N21/359 ,  G01N35/00613 ,  G01N2021/8411 ,  G01N2021/8416 ,  G01N2021/8427 ,  G01N2201/129

Abstract: Die vorliegende Erfindung betrifft ein Verfahren zur Bestimmung des Aushärtungsgrades von mindestens einer auf einer Trägerplatte angeordneten Polymerschicht, insbesondere von mindestens einer Harzschicht (insbesondere einem Melamin-Formaldehyd-Harz, einem Melamin-Harnstoff-Formaldehyd-Harz oder einem Harnstoff-Formaldehyd-Harz), umfassend die Schritte Aufnehmen von mindestens einem NIR-Spektrum (z.B wie in Figur 1) der auf der mindestens einen Trägerplatte angeordneten Polymerschicht nach dem Aushärten der mindestens einen Polymerschicht mit der Trägerplatte unter Verwendung von mindestens einem NIR-Detektor in einem Wellenlängenbereich zwischen 500 nm und 2500 nm, bevorzugt zwischen 700 nm und 2000 nm, insbesondere bevorzugt zwischen 900 nm und 1700 nm; Bestimmen des Aushärtungsgrades der mindestens einen Polymerschicht durch Vergleich des für die mindestens eine Polymerschicht ermittelten NIR-Spektrums mit mindestens einem für mindestens eine Referenzprobe der mindestens einen Polymerschicht mit bekanntem Aushärtungsgrad (bestimmt mittels eines Säuretests mit 4 M Salzsäure) ermittelten NIR-Spektrums mittels einer multivarianten Datenanalyse (MDA), wobei das mindestens eine für die mindestens eine Referenzprobe ermittelte NIR-Spektrum mit bekanntem Aushärtungsgrad der mindestens einen Polymerschicht nach dem Aushärten der Polymerschicht mit der Trägerplatte unter Verwendung desselben NIR-Detektors in einem Wellenlängenbereich zwischen 500 nm und 2500 nm, bevorzugt zwischen 700 nm und 2000 nm, insbesondere bevorzugt zwischen 900 nm und 1700 nm vorher bestimmt wurde. Die Polymerschicht weist eine Dicke zwischen 10 und 150 µm, bevorzugt zwischen 20 und 100 µm, insbesondere bevorzugt zwischen 30 und 80 µm auf.

Abstract translation: 本发明涉及一种用于确定至少一个的固化程度上的承载板布置聚合物层，特别是至少一个树脂层（特别是三聚氰胺 - 甲醛树脂，三聚氰胺 - 脲 - 甲醛树脂或脲甲醛树脂） 包括：使用至少一个NIR检测器在500纳米之间的波长范围中的至少一个聚合物层的固化于背板之后（图1中例如为）接收至少一个NIR光谱中的至少一个承载板设置的聚合物层的步骤 2500纳米，优选700纳米至2000纳米之间，更优选为900纳米至1700纳米之间; 通过比较所确定的用于与具有固化的公知的程度至少一个聚合物层中的至少一个参比样品中的至少一种（如通过酸测试用4M盐酸确定的）所述至少一个聚合物层NIR光谱确定至少一个聚合物层的固化度使用多变量获得NIR光谱 数据分析（MDA），其特征在于，所述至少一个用于所述至少一个参考样本的NIR光谱确定具有已知程度的至少所述聚合物层固化到支撑板后优选具有使用相同的NIR检测器在500纳米和2500纳米之间的波长范围内的聚合物层固化， 物700至2000nm，更优选为900纳米至1700之前纳米之间之间确定。 所述聚合物层具有10至150微米之间的厚度，优选为20至100微米，更优选30至80微米。

公开(公告)号：EP2480875A4

公开(公告)日：2017-10-11

申请号：EP10818164

申请日：2010-09-24

Applicant: COMMW SCIENT IND RES ORG

Inventor： FORRESTER SEAN THOMAS ,  JANIK LESLIE JOSEPH ,  MCLAUGHLIN MICHAEL JOHN

IPC: G01N21/3563 ,  G01N21/359 ,  G01N33/24

CPC classification number: G01N21/359 ,  G01N21/3563 ,  G01N33/241 ,  G01N2201/129

公开(公告)号：EP3218695A1

公开(公告)日：2017-09-20

申请号：EP15797779.4

申请日：2015-11-11

Applicant: SpectraSensors, Inc.

Inventor： LIU, Xiang ,  FEITISCH, Alfred ,  HELBLEY, Keith,Benjamin ,  TEDESCO, James

IPC: G01N21/39 ,  G01N21/65 ,  G01N21/3504

CPC classification number: G06F17/5009 ,  G01J3/42 ,  G01J3/44 ,  G01N21/3504 ,  G01N21/39 ,  G01N21/65 ,  G01N2021/3545 ,  G01N2021/399 ,  G01N2201/0612 ,  G01N2201/129 ,  G06F17/10

Abstract: Background composition concentration data representative of an actual background composition of a sample gas can be used to model absorption spectroscopy measurement data obtained for a gas sample and to correct an analysis of the absorption spectroscopy data (e.g. for structural interference and collisional broadening) based on the modeling.

Abstract translation: 表示样品气体的实际背景组成的背景组分浓度数据可以用于模拟针对气体样品获得的吸收光谱测量数据，并且基于该吸收光谱数据的分析（例如，用于结构干涉和碰撞展宽）来校正吸收光谱数据的分析 造型。

公开(公告)号：EP3198262A1

公开(公告)日：2017-08-02

申请号：EP15824436.8

申请日：2015-07-21

Applicant: 7386819 Manitoba Ltd.

Inventor： PRYSTUPA, David

IPC: G01N21/95 ,  A22C17/00 ,  G01N21/25 ,  G01N21/65 ,  G01S15/88 ,  G01J3/42

CPC classification number: G01N33/12 ,  A22C17/0073 ,  G01N21/3563 ,  G01N21/65 ,  G01N21/94 ,  G01N29/07 ,  G01N2021/3595 ,  G01N2201/129 ,  G01S7/52036 ,  G01S15/88

Abstract: A method and device for detection of bone in meat identifies fragments larger than about 1 mm using spectral optical imaging and ultrasound. Spectral imaging can detect foreign material proximate to the surface and ultrasound can detect material within the sample. The sample is irradiated by light and reflected light or Raman scattered light measured. The sample is similarly irradiated by ultrasound and reflected or transmitted sound waves give a set of amplitude data points, which include temporal delay. These data points are then processed by statistical methods to derive a set of vectors in n-dimensional space, which are compared to a calibrated data set of derived vectors which have distinct identifying loci for each type of surface, are indicative of the presence or absence of defects.

Abstract translation: 用于检测肉中骨的方法和装置使用光谱光学成像和超声来识别大于约1mm的碎片。 光谱成像可以检测表面附近的异物，超声波可以检测样品中的物质。 用光和反射光或拉曼散射光测量样品。 样本同样由超声波照射，反射或发射的声波给出一组振幅数据点，其包括时间延迟。 然后通过统计学方法处理这些数据点以得出n维空间中的一组向量，将其与每个类型的表面具有不同识别基因座的导出向量的校准数据集进行比较，表明存在或不存在 的缺陷。