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公开(公告)号：EP3045445B1
公开(公告)日：2019-08-07
申请号：EP16152929.2
申请日：2011-08-16
IPC分类号： C07C49/248 , C07C309/67 , C07D211/06 , A61K31/121 , A61P35/00
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公开(公告)号：EP2606021A4
公开(公告)日：2014-05-07
申请号：EP11818654
申请日：2011-08-16
申请人： UNIV TOKYO , ANDROSCIENCE CORP
IPC分类号： C07C49/248 , A61K31/121 , A61P35/00 , C07C309/67 , C07D211/06
CPC分类号： C07C49/248 , C07C49/235 , C07C49/255 , C07C69/16 , C07C217/22 , C07C217/60 , C07C235/82 , C07C307/02 , C07C309/65 , C07C309/66 , C07C309/73 , C07C317/24 , C07C2601/14 , C07C2601/16 , C07D213/68 , C07D295/112 , C07D295/13 , C07F9/06 , C07F9/09 , C07F9/12 , C07F9/32 , C07F9/3282
摘要： This invention relates to compounds of Formula (I), (II), or (III) as shown in the specification, which contain a 1,5-diphenylpenta-1,4-dien-3-one backbone. These compounds can be used to treat cancer, inflammatory disease, or autoimmune disease.
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3.发明公开PROCESS FOR THE PREPARATION OF ETHYL-N-(2, 3-DICHLORO-6-NITROBENZYL) GLYCINE HYDROCHLORIDE 审中-公开METHOD FOR PRODUCTION乙基-N-（2-，3-二氯-6-硝基苄基）甘氨酸盐酸盐
公开(公告)号：EP2114856A1
公开(公告)日：2009-11-11
申请号：EP08702079.8
申请日：2008-02-06
申请人： Cipla Limited
IPC分类号： C07C205/42 , C07D487/04 , C07D239/84 , C07C309/67
CPC分类号： C07C303/28 , C07C227/16 , C07C309/66 , C07C229/14
摘要： The invention relates to a process for the preparation of anagrelide, and for the preparation of intermediates for use in preparing anagrelide. The invention also relates to the inteπnediates per se, in particular compounds of formula (V) where R constitutes a suitable leaving group, which may not be hydrogen. The R group may be is selected from: (i) -SiR13, (ii) -CH2Ar, (iii) -COOR2, and (iv) sulfonates such as -SO2R3.
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公开(公告)号：EP2102139A2
公开(公告)日：2009-09-23
申请号：EP07874033.9
申请日：2007-11-01
IPC分类号： C07C33/02 , C07C43/178 , C07C69/007 , C07C69/24 , C07C69/40 , C07C69/587 , C07C69/96 , C07C309/67 , C07C323/14 , C07F9/113 , A61K31/045 , A61K31/075 , A61K31/10 , A61K31/047 , A61K31/22
CPC分类号： C07F9/113 , A61K31/045 , A61K31/047 , A61K31/075 , A61K31/10 , A61K31/22 , A61K31/225 , A61K31/232 , A61K31/255 , A61K31/265 , A61K31/661 , A61K45/06 , C07C69/007 , C07C69/24 , C07C69/40 , C07C69/587 , C07C69/96 , C07C305/14 , C07C323/14 , A61K2300/00
摘要： The present invention relates to compositions comprising at least omega-3 lipid compounds substituted at the 2-positions having therapeutic activity. More specifically, the present invention relates to a composition comprising at least omega-3 lipid compounds substituted at the 2-position, counted from the functional group (X) of the omega-3 lipid compound, wherein the omega-3 lipid compounds comprise: a compound of general formula (I): and a compound of formula (II): wherein R1 and R2 are the same or different and are chosen from a hydrogen atom, a hydroxy group, an alkyl group, a halogen atom, an alkoxy group, an acyloxy group, an acyl group, an alkenyl group, an alkynyl group, an aryl group, an alkylthio group, an alkoxycarbonyl group, a carboxy group, an alkylsulfinyl group, an alkylsulfonyl group, an amino group, and an alkylamino group; and X represents a carboxylic acid or a derivative thereof, a carboxylate, a carboxylic anhydride, a hydroxymethyl (-CH2OH) or a pro-drug thereof, or a carboxamide, or any pharmaceutically acceptable complex, salt, solvate, or pro-drug, with the provisos that: R1 and R2 are not simultaneously hydrogen.
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5.发明授权Mehrfunktionelle Verbindungen mit alpha-Diazo-beta-ketoester- und Sulfonsäureester-Einheiten und Verfahren zu ihrer Herstellung. 失效具有用于它们的制备的α-重氮基β-酮酯和磺酸酯单元和方法的多官能化合物。
公开(公告)号：EP0456073B1
公开(公告)日：1995-10-25
申请号：EP91106918.5
申请日：1991-04-29
IPC分类号： C07C309/73 , G03F7/004 , C07D333/34 , C07C309/65 , C07D251/32 , C07C309/67 , C07C309/77 , C07D209/48
CPC分类号： C07D209/48 , C07C309/65 , C07C309/67 , C07C309/73 , C07C309/77 , C07C2601/14 , C07C2603/74 , C07D251/32 , C07D333/34 , G03F7/0163
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6.发明公开INHIBITORS OF ERCC1-XPF AND METHODS OF USING THE SAME 审中-公开INHIBITOREN VON ERCC1-XPF UND VERFAHREN ZUR VERWENDUNG DAVON
公开(公告)号：EP3073825A4
公开(公告)日：2017-06-21
申请号：EP14863805
申请日：2014-11-25
申请人： UNIV TOLEDO
IPC分类号： A61K31/12 , A61K31/185 , A61K31/19 , A61K31/255 , A61K33/24 , A61K45/06 , A61P35/00 , A61P35/04 , A61P43/00 , C07C309/47 , C07C309/67 , C07C309/73 , C07C317/36 , C07C323/66
CPC分类号： A61K33/24 , A61K31/185 , A61K31/255 , A61K45/06 , C07C309/47 , C07C309/67 , C07C309/73 , C07C317/36 , C07C323/66 , A61K2300/00
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公开(公告)号：EP1769286B1
公开(公告)日：2015-09-09
申请号：EP05774169.6
申请日：2005-07-11
申请人： BASF SE
IPC分类号： C07C309/65 , C07C309/67 , C07C309/73 , C07C309/74 , C07C309/75 , C07C381/00 , C07D209/86 , C07F9/09 , G03F7/00 , G03F7/004 , G03F7/038 , G03F7/039
CPC分类号： C07C309/67 , B33Y70/00 , C07C309/65 , C07C309/73 , C07C309/74 , C07C309/75 , C07C381/00 , C07C2603/18 , C07C2603/20 , C07C2603/66 , C07D209/86 , C07F9/097 , G03F7/0007 , G03F7/0045 , G03F7/0382 , G03F7/0392 , Y10S430/12
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8.发明授权Aromatic sulfonate derivative, polyarylene, sulfonated polyarylene and production method thereof, macromolecular solid electrolyte, and proton conductive membrane 有权芳香族Sulfonatederivate，聚亚芳基，聚亚芳基磺化，涉及它们的制备方法，高分子固态电解质和质子传导膜
公开(公告)号：EP1431281B1
公开(公告)日：2006-05-10
申请号：EP03028999.5
申请日：2003-12-17
IPC分类号： C07C309/67 , C08G61/10 , C08G61/12 , H01M10/40
CPC分类号： C07C309/67 , C08G61/02 , C08G61/10 , C08G2261/312 , C08K5/42 , C08L65/00 , C08L65/02 , H01B1/122 , H01M8/1025 , H01M8/1027 , H01M8/1032 , H01M8/1039 , H01M2300/0082 , Y02P70/56
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9.发明公开Polyfunctional sulfonamides and sulfonates and process for preparing them 审中-公开Mehrfunktionelle Sulfonamide和Sulfonsäureestersowie Verfahren zu ihrer Herstellung
公开(公告)号：EP1447397A1
公开(公告)日：2004-08-18
申请号：EP03003611.5
申请日：2003-02-17
发明人： Vogel, Pierre , Bouchez, Laure , Dubbaka, Srinivas , Turks, Maris
IPC分类号： C07C313/02 , C07C303/02 , C07C303/36 , C07C303/28 , C07C309/81 , C07C311/03 , C07C311/14 , C07C309/67 , C07D277/52 , A61K31/18 , A61K31/185 , A61K31/255 , A61P31/04 , A61P31/10
CPC分类号： C07C303/36 , C07C303/02 , C07C303/28 , C07C309/67 , C07C309/81 , C07C311/03 , C07C311/14 , C07C313/02 , C07C2601/14 , C07C2602/42 , C07D277/52
摘要： The present invention relates to a process for preparing sulfonyl halides comprising the steps of a) reacting an enoxymetal, allylsilane or allylstannane compound, preferably in the presence of a diene, with sulphur dioxide and b) adding a suitable halogen source to the metal sulfinate intermediate of step a). Furthermore, the present invention relates to new sulfonyl chlorides, bromides, and iodides, sulfonamides and sulfonates. In addition, the present invention teaches the use of the new multifunctional sulfonamides and sulfonates for the preparation of a medicament, bacteriocides, fungicides, pesticides, and herbicides as well as the use of sulfonyl chlorides for the preparation of sulfonamides and sulfonates.
摘要翻译： 本发明涉及一种制备磺酰卤的方法，包括以下步骤：a）使环氧金属，烯丙基硅烷或烯丙基锡烷化合物，优选在二烯存在下与二氧化硫反应，和b）将合适的卤素源加入金属亚磺酸盐中间体 的步骤a）。 此外，本发明涉及新的磺酰氯，溴化物和碘化物，磺酰胺和磺酸盐。 此外，本发明教导了新的多官能磺酰胺和磺酸盐用于制备药物，杀菌剂，杀真菌剂，农药和除草剂的用途，以及使用磺酰氯制备磺酰胺和磺酸盐。
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公开(公告)号：EP0906091A4
公开(公告)日：2004-07-21
申请号：EP97919990
申请日：1997-03-27
发明人： SOLL RICHARD M , LU TIANBAO , FEDDE CYNTHIA L , TOMCZUK BRUCE E , ILLIG CARL
IPC分类号： A61K31/00 , A61K31/165 , A61K31/18 , A61K31/275 , A61K31/277 , A61K31/41 , A61K31/415 , A61K31/433 , A61K31/44 , A61K31/4406 , A61K31/47 , A61K31/472 , A61P1/00 , A61P1/18 , A61P7/00 , A61P7/02 , A61P43/00 , C07C45/29 , C07C45/71 , C07C47/277 , C07C281/18 , C07C309/67 , C07C309/73 , C07C309/74 , C07C309/75 , C07C309/77 , C07C311/21 , C07C323/66 , C07D213/70 , C07D213/71 , C07D215/36 , C07D217/02 , C07D231/14 , C07D231/18 , C07D233/52 , C07D285/14 , C07D317/40 , C07D333/34 , A61K31/155 , A61K31/24 , A61K31/40 , C07C47/228 , C07C47/24 , C07C47/27 , C07C231/18 , C07C317/40
CPC分类号： C07D285/14 , C07C45/29 , C07C45/71 , C07C47/277 , C07C281/18 , C07C309/73 , C07C309/74 , C07C309/75 , C07C309/77 , C07C311/21 , C07C323/66 , C07C2601/02 , C07D213/71 , C07D215/36 , C07D217/02 , C07D231/18 , C07D233/52 , C07D317/40 , C07D333/34 , C07C47/575
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