专利检索 ipc:"C07D411/12" 第 10 页

91.

发明专利
失效

公开(公告)号：JPH068290B2

公开(公告)日：1994-02-02

申请号：JP4465988

申请日：1988-02-29

申请人： BAYER AG

发明人： BORUFUGANGU KUREEMAA , YOAHIMU BAISUMYURAA , DEIITAA BERUKU , SHUTEFUAN DOTSUTSUMAN

IPC分类号： A01N43/28 , A01N43/30 , C07D317/72 , C07D327/04 , C07D405/06 , C07D407/12 , C07D411/06 , C07D411/12 , C07D411/14 , C07D413/06 , C07D417/12

92.

发明专利
SUBSTITUTED PYRIDINE COMPOUND 失效

公开(公告)号：JPH05320156A

公开(公告)日：1993-12-03

申请号：JP41859890

申请日：1990-12-27

申请人： MONSANTO CO

发明人： SHIYURITSUDOHAA GAJIYANAN HETS , REN FUANGU RII , ROBAATO DOUSON BURIYANTO

IPC分类号： A01N43/40 , A01N43/78 , A01N43/84 , C07D401/04 , C07D401/12 , C07D405/04 , C07D405/12 , C07D409/04 , C07D409/12 , C07D411/04 , C07D411/12 , C07D413/04 , C07D413/12 , C07D417/04 , C07D417/12

93.

发明专利
CIRCULAR RENIN INHIBITOR CONTAINING 3(S)-AMINO- 4-CYCLOHEXYL-2(R)-HYDROXYBUTYRIC ACID OR 4- CYCLOHEXYL-(2R,3S)-DIHYDROXYBUTYRIC ACID OR RELATED ANALOG 失效

公开(公告)号：JPH05222005A

公开(公告)日：1993-08-31

申请号：JP15246092

申请日：1992-06-11

申请人： MERCK & CO INC

发明人： DARUJITO ESU DANOA , AASAA EE PACHIETSUTO , UIRIAMU JIEE GURIINRII , UIRIAMU ETSUCHI PAASONZU , TOMASU EE HARUGUREN , AN II UEEBAA , RIFU YANGU

IPC分类号： A61K31/335 , A61K31/357 , A61K31/39 , A61K31/395 , A61K31/40 , A61K31/435 , A61K31/44 , A61K31/4427 , A61K31/443 , A61K31/445 , A61K31/495 , A61K31/535 , A61K38/00 , A61P5/38 , A61P9/00 , A61P9/12 , A61P27/02 , A61P27/06 , A61P31/12 , A61P43/00 , C07D225/02 , C07D245/02 , C07D267/00 , C07D273/00 , C07D273/01 , C07D273/02 , C07D281/00 , C07D285/00 , C07D291/02 , C07D313/00 , C07D321/00 , C07D323/00 , C07D327/00 , C07D327/02 , C07D401/12 , C07D403/12 , C07D405/12 , C07D411/12 , C07D413/12 , C07D417/12 , C07D419/12 , C07D453/02 , C07D487/04 , C07F9/6527 , C07F9/6558 , C07F9/6561 , C07K5/02 , C07K5/065 , C07K5/078 , C07K5/097

94.

发明专利
AMINE DERIVATIVE, PRODUCTION THEREOF AND INSECTICIDE 失效

公开(公告)号：JPH054966A

公开(公告)日：1993-01-14

申请号：JP18701991

申请日：1991-07-02

申请人： NIPPON SODA CO

发明人： OISHI HARUHITO , IIHAMA TERUYUKI , ISHIMITSU KEIICHI , YAMADA TOMIO , HATANO RENPEI , TAKAKUSA NOBUO , MITSUI JUN

IPC分类号： A01N43/40 , A01N43/54 , A01N43/58 , A01N43/60 , A01N43/78 , C07D213/36 , C07D213/61 , C07D213/63 , C07D237/08 , C07D237/12 , C07D241/12 , C07D241/16 , C07D277/20 , C07D277/28 , C07D277/32 , C07D401/12 , C07D403/12 , C07D405/12 , C07D409/12 , C07D411/12 , C07D417/12

摘要： PURPOSE:To provide new compounds useful as an insecticide and showing an excellent insecticidal effect especially to cotton aphid, green rice leafhopper of an organophosphorus compound-or carbamate-resistant line, etc. CONSTITUTION:Compounds of formula I (R is heterocycle; X is alkylene, alkylidene or-NR -; R is H, alkyl, etc.; R is H, alkyl, alkenyl, etc.; A, B and D are C, hetero or single bond; E is-CO-,-CS-,-SO2-, etc.; Q is H, alkyl, alkenyl, nitro, etc.), e.g. 1-(2-chloro-5-pyridylmethylamino)-1-cyclohexan-3-one. The compounds of formula I can be obtained by reacting a compound of formula II [Z is S(O)n, R , OR , etc., (R is 1-4C alkyl, phenyl, etc.; R is 1-4C alkyl, phenyl, etc.; n is 0-2)] with a compound of formula III in the presence of a Lewis catalyst as necessary in a solvent such as toluene or without using a solvent at room temperature-reflux temperature.

95.

发明专利
失效

公开(公告)号：JPH045673B2

公开(公告)日：1992-02-03

申请号：JP3237689

申请日：1989-02-10

申请人： TAKEDA CHEMICAL INDUSTRIES LTD

发明人： SUGIHARA HIROSADA , HIRATA MINORU

IPC分类号： A61K31/385 , A61K31/39 , A61K31/495 , A61P11/00 , C07D327/02 , C07D411/06 , C07D411/12

96.

发明专利
失效

公开(公告)号：JPH0233031B2

公开(公告)日：1990-07-25

申请号：JP19045881

申请日：1981-11-27

申请人： ISUCHI* DE ANJERI SPA

发明人： ENZO SEREDA , ARUTSURO DONETSUTEI , PIERO DERU SORUDATO , MARIO BERUGAMASUKI

IPC分类号： C07D233/00 , A61K31/415 , A61K31/4164 , A61K31/42 , A61P1/04 , C07C67/00 , C07C241/00 , C07C257/04 , C07D233/54 , C07D233/64 , C07D405/12 , C07D411/12 , C07D413/12

97.

发明专利
PIPERAZINE DERIVATIVE AND SALT THEREOF 失效

公开(公告)号：JPH01316363A

公开(公告)日：1989-12-21

申请号：JP2555589

申请日：1989-02-03

申请人： TOYAMA CHEMICAL CO LTD

发明人： HIRAIWA TORU , TAKEDA KENJI , NAKANO JOJI , SUTANI MINEICHI , FURUHATA KUNIKAZU , TAKADA MAKOTO , KAWABUCHI HIROYO , WATANABE ISAO

IPC分类号： A61K31/00 , A61K31/495 , A61P9/00 , A61P9/08 , C07D20060101 , C07D207/26 , C07D207/27 , C07D213/26 , C07D215/12 , C07D221/16 , C07D233/54 , C07D235/08 , C07D271/10 , C07D271/12 , C07D295/04 , C07D295/06 , C07D295/073 , C07D295/096 , C07D295/135 , C07D295/155 , C07D313/12 , C07D333/54 , C07D337/12 , C07D401/00 , C07D401/12 , C07D403/06 , C07D405/00 , C07D405/12 , C07D409/00 , C07D409/12 , C07D411/12 , C07D413/12 , C07D417/00 , C07D417/12 , C07D491/04 , C07D491/044 , C07D491/052 , C07D491/14 , C07D495/04 , C07D495/14 , C07D521/00 , C07F7/18

摘要： NEW MATERIAL:A compound expressed by formula I [A is atom group necessary for constructing pyridine nucleus or substituted NO2-substituted benzene nucleus together with C to be bonded; X is H, halogen, alkyl or OH, etc.; B is CH2CH2, CH=CH, O or S, etc.; R is H, halogen, NO2 or alkyl; R is R other than NO2; R aryl or heterocyclic ring group which may be substituted (by halogen, OH, NO2, NH2, alkenyl, acyl or aryl, etc.)] and salt of said compound. EXAMPLE:5-{4-[(E)-3-phenylallyl]piperazine-1-yl}-10,11-dihydro-5H- benzo[4,5]cyclohepta[1,2-b]pyridine. USE:Remedy for affection of cerebral blood flow and sequela of said affection, having not only excellent vasodilation action for cerebral selectivity but also excellent protecting action for cerebrum cell. PREPARATION:For instance, a compound expressed by formula II (Y is eliminating group) is reacted with a compound expressed by formula III in the presence or non-presence of solvent and base to obtain a compound expressed by formula I.