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    Novel hypervalent iodine compound having quaternary alkylammonium sulfonate part
    6.
    发明专利
    Novel hypervalent iodine compound having quaternary alkylammonium sulfonate part 审中-公开
    具有季铵盐磺酸盐的新型高价碘化合物

    公开(公告)号：JP2013129645A

    公开(公告)日：2013-07-04

    申请号：JP2011290626

    申请日：2011-12-21

    申请人： Tokyo Kasei Kogyo Kk ,  東京化成工業株式会社

    发明人： TOGO HIDEO ,  SUZUKI YUSUKE ,  IINUMA MASATAKA ,  MORIYAMA KATSUHIKO ,  TAKATSUKI KENICHI

    IPC分类号： C07C211/63 ,  C07C209/12 ,  C07D295/06 ,  C07D295/08

    摘要： PROBLEM TO BE SOLVED: To develop a novel hypervalent iodine compound in which in an oxidation reaction that uses a hypervalent iodine compound represented by diacetoxy iodobenzene, an unreacted hypervalent iodine compound and a by-product univalent iodine compound can be easily removed and recovered by an extraction operation.SOLUTION: A quaternary alkyl ammonium salt part is coupled with a hypervalent iodine compound to solve the problem. As a result, the unreacted hypervalent iodine compound and the by-product univalent iodine compound, both being generated after the completion of an oxidation reaction, can be removed and recovered by cleaning and the extraction operation.

    摘要翻译： 要解决的问题：为了开发新的高价碘化合物，其中在使用由二乙酰氧基碘苯代表的高价碘化合物的氧化反应中，未反应的高价碘化合物和副产物一价碘化合物可以容易地通过 提取操作。解决方案：将季铵盐部分与高价碘化合物偶联以解决问题。 结果，可以通过清洗和萃取操作去除和回收在氧化反应完成之后产生的未反应的高价碘化合物和副产物一价碘化合物。

    Adsorbent for protein separation/purification
    9.
    发明专利
    Adsorbent for protein separation/purification 有权
    蛋白质分离/纯化的吸附剂

    公开(公告)号：JP2013072716A

    公开(公告)日：2013-04-22

    申请号：JP2011211274

    申请日：2011-09-27

    申请人： Tosoh Corp ,  東ソー株式会社 ,  Sagami Chemical Research Institute ,  公益財団法人相模中央化学研究所

    发明人： KAKIYA HITOSHI ,  TOYOSHIMA TOSHISHIGE ,  ONO RYUTA ,  INOUE TOMOKO ,  SHIMIZU ERIKA

    IPC分类号： G01N30/88 ,  B01J20/22 ,  B01J20/24 ,  B01J20/26 ,  B01J20/281 ,  B01J20/30 ,  C07D213/38 ,  C07D213/56 ,  C07D213/70 ,  C07D213/74 ,  C07D295/02 ,  C07D295/06 ,  C07D295/08 ,  C07D295/12 ,  C07D295/18 ,  C07K1/14

    摘要： PROBLEM TO BE SOLVED: To provide an adsorbent for separating/purifying useful protein such as immunoglobulin.SOLUTION: The adsorbent for separating/purifying protein is obtained by fixing a group indicated by a general formula (1) to an insoluble carrier through a carbonyl group. (In the formula, Ar indicates a phenyl group or a pyridyl group that may be replaced with a group selected from a halogen atom, an alkyl group of a carbon number 1 to 4, a haloalkyl group of the carbon number 1 to 4, an alkoxy group of the carbon number 1 to 4, an alkylsulfonyl group of the carbon number 1 to 4, a hydroxyl group, a cyano group, the phenyl group, an acyl group of the carbon number 1 to 5, and a nitro group or the like, X indicates a single bond, the carbonyl group, a sulfonyl group, or an alkylene group of the carbon number 1 or 2, and n indicates 1 or 2.)

    摘要翻译： 待解决的问题：提供用于分离/纯化有用蛋白质如免疫球蛋白的吸附剂。 解决方案：通过将通式（1）表示的基团通过羰基固定在不溶性载体上而获得用于分离/纯化蛋白质的吸附剂。 （式中，Ar表示可以被选自卤原子，碳数1〜4的烷基，碳数1〜4的卤代烷基，碳数1〜4的卤代烷基取代的苯基或吡啶基， 碳数1至4的烷氧基，碳数1至4的烷基磺酰基，羟基，氰基，苯基，碳数1至5的酰基和硝基或 X表示单键，羰基，磺酰基或碳数1或2的亚烷基，n表示1或2）。权利要求：（C）2013，JPO＆INPIT