公开(公告)号：US10155966B2

公开(公告)日：2018-12-18

申请号：US15013366

申请日：2016-02-02

Applicant: Inbicon A/S

Inventor： Borge Holm Christensen ,  Lena Holm Gerlach

IPC: B01J19/24 ,  D21C9/18 ,  C12P7/10 ,  C08B15/00 ,  C08B37/00 ,  C08H7/00 ,  C08H8/00 ,  C13B20/16 ,  C13K1/02 ,  C12P7/56 ,  C12P21/00 ,  C12M1/00 ,  C12M1/33 ,  C08B1/00 ,  C12P7/14 ,  C12P19/02 ,  C12P19/14

Abstract: The present invention provides an apparatus and a method for conversion of cellulosic material, such as chopped straw and corn stover, and household waste, to ethanol and other products. The cellulosic material is subjected to continuous hydrothermal pre-treatment without addition of chemicals, and a liquid and a fiber fraction are produced. The fiber fraction is subjected to enzymatic liquefaction and saccharification. The method of the present invention comprises: performing the hydrothermal pre-treatment by subjecting the cellulosic material to at least one soaking operation, and conveying the cellulosic material through at least one pressurized reactor, and subjecting the cellulosic material to at least one pressing operation, creating a fiber fraction and a liquid fraction; selecting the temperature and residence time for the hydrothermal pretreatment, so that the fibrous structure of the feedstock is maintained and at least 80% of the lignin is maintained in the fiber fraction.

公开(公告)号：US20160355858A1

公开(公告)日：2016-12-08

申请号：US15117969

申请日：2015-02-11

Applicant: Inbicon A/S ,  Odebrecht Agroindustrial SA

Inventor： Martin Dan Jeppesen ,  Carlos Eduardo Calmonovici ,  Edmar Lopes Faleiros

IPC: C12P19/14 ,  C10L5/44 ,  C07C31/08 ,  C12P19/02 ,  C12P7/14

CPC classification number: C12P19/14 ,  C07C31/08 ,  C10L5/445 ,  C10L2290/24 ,  C10L2290/26 ,  C10L2290/544 ,  C10L2290/547 ,  C12P7/10 ,  C12P7/14 ,  C12P19/02 ,  C12P2201/00 ,  C12Y302/01004 ,  Y02E50/10 ,  Y02E50/16 ,  Y02E50/30

Abstract: The current invention concerns methods and products related to the production of alcohol from sugar cane and/or sweet sorghum with integration of 1st and 2nd generation (1G/2G) biorefining, thus comprising the integrated conversion of primary and secondary soft lignocellulosic biomass. In particular, methods of processing sugar cane and/or sweet sorghum feedstock are disclosed, said methods comprising the steps of providing raw juice from the feedstock, recovering a residual bagasse, pretreating the bagasse and mixing it with some quantity of raw juice, and hydrolyzing the pretreated bagasse enzymatically.

Abstract translation: 本发明涉及与通过第一代和第二代（1G / 2G）生物精炼相结合的甘蔗和/或甜高粱生产醇的方法和产品，从而包括初级和次级软木质纤维素生物质的综合转化。 特别地，公开了处理甘蔗和/或甜高粱原料的方法，所述方法包括以下步骤：从原料中提供原汁，回收残余的甘蔗渣，预处理甘蔗渣并将其与一定量的原汁混合并水解 预处理的甘蔗渣酶促。

公开(公告)号：US20150232579A1

公开(公告)日：2015-08-20

申请号：US14702210

申请日：2015-05-01

Applicant: Inbicon A/S

Inventor： Borge Holm Christensen ,  Lena Holm Gerlach

IPC: C08B1/00 ,  C12P7/14 ,  C12P19/02 ,  C12P7/10 ,  C12P19/14

CPC classification number: C12P7/10 ,  B01J19/245 ,  B01J2219/00006 ,  C08B1/003 ,  C08B15/00 ,  C08B37/0057 ,  C08H6/00 ,  C08H8/00 ,  C12M21/12 ,  C12M45/02 ,  C12M45/04 ,  C12M45/09 ,  C12M45/20 ,  C12P7/14 ,  C12P7/56 ,  C12P19/02 ,  C12P19/14 ,  C12P21/00 ,  C12P2201/00 ,  C12P2203/00 ,  C13B20/165 ,  C13K1/02 ,  D21C9/18 ,  Y02E50/16 ,  Y02E50/17

Abstract: The present invention provides an apparatus and a method for conversion of cellulosic material, such as chopped straw and corn stover, and household waste, to ethanol and other products. The cellulosic material is subjected to continuous hydrothermal pre-treatment without addition of chemicals, and a liquid and a fibre fraction are produced. The fibre fraction is subjected to enzymatic liquefaction and saccharification. The method of the present invention comprises: performing the hydrothermal pre-treatment by subjecting the cellulosic material to at least one soaking operation, and conveying the cellulosic material through at least one pressurised reactor, and subjecting the cellulosic material to at least one pressing operation, creating a fibre fraction and a liquid fraction; selecting the temperature and residence time for the hydrothermal pretreatment, so that the fibrous structure of the feedstock is maintained and at least 80% of the lignin is maintained in the fibre fraction.

Abstract translation: 本发明提供了将诸如切碎的秸秆和玉米秸秆以及家庭废物的纤维素材料转化成乙醇和其它产品的装置和方法。 在不添加化学物质的情况下对纤维素材料进行连续水热预处理，并且生产液体和纤维部分。 纤维部分进行酶液化和糖化。 本发明的方法包括：通过使纤维素材料进行至少一次均热操作，并通过至少一个加压反应器输送纤维素材料，并对纤维素材料进行至少一次按压操作来进行水热预处理， 产生纤维部分和液体部分; 选择水热预处理的温度和停留时间，从而维持原料的纤维结构，并且在纤维部分中保持至少80％的木质素。

公开(公告)号：US20150191758A1

公开(公告)日：2015-07-09

申请号：US14418667

申请日：2013-08-01

Applicant: Inbicon A/S

Inventor： Jan Larsen ,  Niels Nielsen Poulsen ,  Martin Dan Jeppesen ,  Kit Kellebjerg Mogensen

IPC: C12P19/14 ,  C13K1/02 ,  C13K13/00 ,  C12P19/02

CPC classification number: C12P19/14 ,  C12P7/10 ,  C12P19/02 ,  C12P2201/00 ,  C13K1/02 ,  C13K13/002 ,  D21C1/04 ,  D21C3/04 ,  Y02E50/16

Abstract: The invention relates, in general, to methods of processing lignocellulosic biomass to fermentable sugars and to methods that rely on hydrothermal pretreatment. Xylose monomer yields comparable to those achieved using two-stage pretreatments can be achieved from soft lignocellulosic biomass feedstocks by pretreating to very low severity in a single-stage pressurized hydrothermal pretreatment, followed by enzymatic hydrolysis to release xylose retained in the solid state. In some embodiments, pretreated biomass is separated into a solid fraction and a liquid fraction, the solid fraction subject to enzymatic hydrolysis, and the separated liquid fraction subsequently mixed with the hydrolysed solid fraction.

Abstract translation: 本发明一般涉及将木质纤维素生物质加工成可发酵糖的方法以及依赖于水热预处理的方法。 可以通过在单级加压水热预处理中预处理至非常低的严重性，然后进行酶水解以释放保持在固体状态的木糖，从而可以从软木质纤维素生物质原料获得与使用两阶段预处理的那些相当的木糖单体产率。 在一些实施方案中，预处理的生物质被分离成固体级分和液体级分，固体级分进行酶水解，并且分离的液体级分随后与水解的固体级分混合。

公开(公告)号：US11118203B2

公开(公告)日：2021-09-14

申请号：US14418667

申请日：2013-08-01

Applicant: Inbicon A/S

Inventor： Jan Larsen ,  Niels Nielsen Poulsen ,  Martin Dan Jeppesen ,  Kit Kellebjerg Mogensen

IPC: C12P19/14 ,  C12P19/02 ,  C13K1/02 ,  C13K13/00 ,  D21C1/04 ,  C12P7/10 ,  D21C3/04

Abstract: The invention relates, in general, to methods of processing lignocellulosic biomass to fermentable sugars and to methods that rely on hydrothermal pretreatment. Xylose monomer yields comparable to those achieved using two-stage pretreatments can be achieved from soft lignocellulosic biomass feedstocks by pretreating to very low severity in a single-stage pressurized hydrothermal pretreatment, followed by enzymatic hydrolysis to release xylose retained in the solid state. In some embodiments, pretreated biomass is separated into a solid fraction and a liquid fraction, the solid fraction subjected to enzymatic hydrolysis, and the separated liquid fraction subsequently mixed with the hydrolysed solid fraction.

公开(公告)号：US20190271017A1

公开(公告)日：2019-09-05

申请号：US16347091

申请日：2017-11-06

Applicant: Inbicon A/S

Inventor： Martin Dan Jeppesen ,  Jan Larsen ,  Kit Haubjerg Mogensen ,  Anna Frederike Gossmann ,  Anna Granly Hansen ,  Laila Thirup ,  Lars Villadsgaard Toft ,  Hanne Risbjerg Sørensen

IPC: C12P19/02 ,  C12P19/14 ,  C13K1/02 ,  C12P7/10 ,  C07G1/00 ,  C08L95/00

Abstract: A method for providing a C5/C6 product from a lignocellulosic material is disclosed, said method comprising the steps: (i) pretreatment of the lignocellulosic material; (ii) solid/liquid separation of the pretreated lignocellulosic material from step (a) into a first solid fraction and a first liquid fraction; (iii) enzymatic fiber hydrolysis of said first solid fraction from step (b) by use of an enzyme composition capable of degrading lignocellulosic material, thereby providing a C5/C6 fiber slurry comprising C5 and/or C6 sugars; (iv) solid/liquid separation of the C5/C6 fiber slurry from step (c) into a second solid fraction and a second liquid fraction; and optionally (v) combining said first liquid fraction and said second liquid fraction for enzymatic mixed sugar hydrolysis (MSH), whereby a MSH C5/C6 product is provided.

公开(公告)号：US10087578B2

公开(公告)日：2018-10-02

申请号：US14910531

申请日：2014-08-11

Applicant: Inbicon A/S

Inventor： Jesper Dohrup ,  Brian Eskesen ,  Kit Kellebjerg Mogensen

IPC: B01J3/02 ,  D21C1/10 ,  C10L5/44 ,  C10L9/08 ,  B01J3/00 ,  B01J3/04 ,  D21C1/02

Abstract: Provided is a discharge device for discharging pretreated biomass from a pressurized reactor. The device comprises: a vessel having an opening to a high pressure region at the top, and configured to be connected with a pressurized biomass pretreatment device; one or more inlet openings situated along the sides of the vessels through which water or liquid may be added; an orifice or valve at a lower part of said vessel, said orifice or valve being configured to eject pretreated biomass, optionally into a pipeline. The discharge device is characterised in that it comprises mechanical agitation means, said agitation means comprising an agitation element arranged in the interior of said vessel at a lower part of said vessel, and being configured to provide agitation of the content of said vessel, wherein said agitation means being adapted to withstand a pressure in the interior of a said vessel of 10 bar or more. The agitation means provides for a temperature equalization within a specific vertical range of heights of an aqueous slurry present in said vessel, thereby eliminating disadvantages of the prior art devices and methods.

公开(公告)号：US09758843B2

公开(公告)日：2017-09-12

申请号：US14378332

申请日：2013-01-16

Applicant: INBICON A/S

Inventor： Jan Larsen ,  Kit Kellebjerg Mogensen ,  Pia Jørgensen

IPC: C13K13/00 ,  C12P19/02 ,  C12P19/14 ,  C12P7/10

CPC classification number: C13K13/002 ,  C12P7/10 ,  C12P19/02 ,  C12P19/14 ,  C12P2201/00 ,  Y02E50/16

Abstract: The invention relates to a method of processing lignocellulosic biomass comprising: providing lignocellulosic biomass feedstock; pretreating said biomass feedstock by continuous hydrothermal pretreatment in a pressurized reactor; measuring xylan number or lignin number in the output stream of pretreated biomass from the pretreatment reactor; and controlling the pretreatment reactor so as to maintain, in the output stream of pretreated biomass, a pre-determined level of measured xylan number or lignin number. The method allows for continuously controlling the digestibility of a lignocellulosic biomass during the step of pretreatment, and accordingly provides a continuous estimate of the severity of the pretreatment.

公开(公告)号：US20150299734A1

公开(公告)日：2015-10-22

申请号：US14253890

申请日：2014-04-16

Applicant: Inbicon A/S

Inventor： Jan Larsen

IPC: C12P7/06

CPC classification number: C12P7/06 ,  A01N65/44 ,  C12N1/16 ,  C12N1/22 ,  C12P7/10 ,  Y02E50/16 ,  Y02E50/17

Abstract: A range of concentrations exists in which fermentation inhibitors derived from pretreatment of lignocellulosic feed stocks inhibit growth of lactic acid bacteria without affecting fermentive yeast. By optimizing levels of fermentation inhibitors to fall within this range, yeast fermentations of lignocellulosic biomass can be conducted under non-sterile conditions with ethanol yields comparable to those achieved under sterile conditions. Optimised inhibitor levels can be achieved by controlling the water/biomass ratio of a lignocellulosic biomass during and after pretreatment, for example by washing the fiber fraction of a previously pretreated lignocellulosic biomass with a pre-defined amount of fresh water or recycled process solutions. Crude extracts of liquid fraction or process solutions from pretreatment of lignocellulosic biomass can also provide an effective anti-baterial treatment for first generation starch fermentations.

Abstract translation: 存在一定范围的浓度，其中衍生自木质纤维素原料的预处理的发酵抑制剂抑制乳酸菌的生长而不影响发酵酵母。 通过优化发酵抑制剂的含量落在此范围内，木质纤维素生物质的酵母发酵可以在非无菌条件下进行，乙醇产量与在无菌条件下达到的相似。 优化的抑制剂水平可以通过在预处理期间和之后控制木质纤维素生物质的水/生物量比来实现，例如通过用预定量的淡水或再循环的处理溶液洗涤先前预处理的木质纤维素生物质的纤维部分。 来自木质纤维素生物质预处理的液体馏分或处理溶液的粗提取物也可为第一代淀粉发酵提供有效的抗物质处理。

公开(公告)号：US20150128933A1

公开(公告)日：2015-05-14

申请号：US14378332

申请日：2013-01-16

Applicant: INBICON A/S

Inventor： Jan Larsen ,  Kit Kellebjerg Mogensen ,  Pia Jørgensen

IPC: C13K13/00

CPC classification number: C13K13/002 ,  C12P7/10 ,  C12P19/02 ,  C12P19/14 ,  C12P2201/00 ,  Y02E50/16

Abstract: The invention relates to a method of processing lignocellulosic biomass comprising: providing lignocellulosic biomass feedstock; pretreating said biomass feedstock by continuous hydrothermal pretreatment in a pressurized reactor; measuring xylan number or lignin number in the output stream of pretreated biomass from the pretreatment reactor; and controlling the pretreatment reactor so as to maintain, in the output stream of pretreated biomass, a pre-determined level of measured xylan number or lignin number. The method allows for continuously controlling the digestibility of a lignocellulosic biomass during the step of pretreatment, and accordingly provides a continuous estimate of the severity of the pretreatment.

Abstract translation: 本发明涉及一种处理木质纤维素生物质的方法，包括：提供木质纤维素生物质原料; 在加压反应器中通过连续水热预处理预处理所述生物质原料; 测量来自预处理反应器的预处理生物质的输出流中的木聚糖数或木质素数; 并控制预处理反应器，以便在预处理的生物质的输出流中维持测定的木聚糖数量或木质素数量的预定水平。 该方法允许在预处理步骤期间连续控制木质纤维素生物质的消化率，因此提供对预处理的严重性的连续估计。