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    Simple measurement tool having reaction regions separated by gel boundary regions
    1.
    发明授权
    Simple measurement tool having reaction regions separated by gel boundary regions 有权

    公开(公告)号：US10809256B2

    公开(公告)日：2020-10-20

    申请号：US14426442

    申请日：2013-10-07

    申请人： KAZUSA DNA RESEARCH INSTITUTE FOUNDATION

    发明人： Osamu Ohara ,  Ken Nonaka

    IPC分类号： G01N33/553 ,  G01N33/543

    摘要： The purpose of the present invention is to provide a simple measurement tool which can rapidly measure various chemical substances contained in environments or from inside a living body by a simple or inexpensive means/method.The present inventions relate to, for example, a simple measurement tool for test substances comprising: at least two reaction regions, each composed of a water-based liquid, the reaction regions being independent of each other; boundary region(s) composed of a gel-type substance that is not or hardly soluble in the water-based liquid; a container holding the reaction regions and the boundary region(s); and magnetic particles carrying a reactive substance immobilized on a surface thereof, in which: the reaction regions are separated from each other via the boundary region(s); and by using external magnetic field-applying means, the magnetic particles can be substantially exclusively transferred from one reaction region to another reaction region through the boundary region separating these reaction regions, while independence of the respective reaction regions and the respective boundary regions and a function of the magnetic particles being maintained.

    Particle manipulation method and particle manipulation device
    8.
    发明授权
    Particle manipulation method and particle manipulation device 有权

    公开(公告)号：US10159909B2

    公开(公告)日：2018-12-25

    申请号：US14901791

    申请日：2013-07-03

    申请人： SHIMADZU CORPORATION ,  KAZUSA DNA RESEARCH INSTITUTE

    发明人： Tetsuo Ohashi ,  Osamu Ohara ,  Ken Nonaka

    IPC分类号： B01D12/00 ,  B01D15/18 ,  B03C1/033 ,  B03C1/28 ,  C07K1/14 ,  C12N15/10 ,  B03C1/01 ,  C12Q1/6806

    摘要： Disclosed is a particle manipulation method including steps of moving particles, which exist in a water-based liquid, into a gelled medium that is insoluble or hardly soluble in the water-based liquid in the water-based liquid, and moving the particles, which exist in the gelled medium, to the outside of the gelled medium. Preferably, the gelled medium is a gel that contains chemically crosslinking polymer. Preferably, the gelled medium has a consistency of 340 to 475. In one embodiment, the movement of the particles existing in the water-based liquid to the gelled medium and the movement of the particles existing inside the gelled medium to the water-based liquid are carried out inside a device, the device being loaded with a plurality of water-based liquids and a gelled medium interposed among the water-based liquids.

    PARTICLE MANIPULATION METHOD AND PARTICLE MANIPULATION DEVICE
    9.
    发明申请
    PARTICLE MANIPULATION METHOD AND PARTICLE MANIPULATION DEVICE 审中-公开
    颗粒操作方法和粒子操纵装置

    公开(公告)号：US20160201114A1

    公开(公告)日：2016-07-14

    申请号：US14901791

    申请日：2013-07-03

    申请人： SHIMADZU CORPORATION ,  KAZUSA DNA RESEARCH INSTITUTE

    发明人： Tetsuo OHASHI ,  Osamu Ohara ,  Ken Nonaka

    IPC分类号： C12Q1/68 ,  B01D15/18 ,  C12N15/10

    CPC分类号： B01D12/00 ,  B01D15/1892 ,  B03C1/01 ,  B03C1/0332 ,  B03C1/288 ,  B03C2201/26 ,  C07K1/145 ,  C12N15/1013 ,  C12Q1/6806

    摘要： Disclosed is a particle manipulation method including steps of moving particles, which exist in a water-based liquid, into a gelled medium that is insoluble or hardly soluble in the water-based liquid in the water-based liquid, and moving the particles, which exist in the gelled medium, to the outside of the gelled medium. Preferably, the gelled medium is a gel that contains chemically crosslinking polymer. Preferably, the gelled medium has a consistency of 340 to 475. In one embodiment, the movement of the particles existing in the water-based liquid to the gelled medium and the movement of the particles existing inside the gelled medium to the water-based liquid are carried out inside a device, the device being loaded with a plurality of water-based liquids and a gelled medium interposed among the water-based liquids.

    摘要翻译： 公开了一种粒子处理方法，包括以下步骤：将存在于水基液体中的颗粒移动到水基液体中的水性液体中不溶或难溶的胶凝介质中，并且使颗粒移动 存在于凝胶介质中，到凝胶介质的外部。 优选地，凝胶介质是含有化学交联聚合物的凝胶。 优选地，凝胶介质的稠度为340至475.在一个实施方案中，存在于水基液体中的颗粒到凝胶介质的移动以及存在于凝胶介质内的颗粒向水性液体的移动 在装置内进行，该装置装载有多个水基液体和介于水基液体之间的凝胶介质。