公开(公告)号：US5366956A

公开(公告)日：1994-11-22

申请号：US026184

申请日：1993-03-01

申请人： Christopher J. Foster ,  Terence Gilkerson ,  Richard Stocker

发明人： Christopher J. Foster ,  Terence Gilkerson ,  Richard Stocker

IPC分类号： C07D213/64 ,  A01N43/40 ,  C07D213/643 ,  C07D413/06 ,  C07D213/84

CPC分类号： C07D213/643 ,  A01N43/40

摘要： Herbicidal compounds ##STR1## in which Q represents a group --C(O)--C(CN).dbd.CH--NR.sup.1 R.sup.2, R.sup.1 and R.sup.2 each independently represents alkyl, or together represent alkylene optionally interrupted by oxygen, m is O or m is an integer from 1 to 3 and the or each Y independently represents halogen or alkyl and n is O or n is an integer from 1 to 5 and the or each X independently represents halogen, alkyl, haloalkyl, cyanoalkyl, alkenyl, alkynyl, alkoxy, haloalkoxy, haloalkylthio, alkenyloxy, alkynyloxy, alkylthio, alkenylthio, alkynylthio, cyano, nitro, alkylsulphonyl, alkysulphinyl, sulphonamido, or phenyl optionally substituted by alkyl, haloalkyl, alkoxy or halogen.

摘要翻译： 除草剂化合物（I）其中Q代表基团-C（O）-C（CN）= CH-NR1R2，R1和R2各自独立地表示烷基，或一起表示任选被氧中断的亚烷基，m是O或 m是1至3的整数，并且每个Y独立地表示卤素或烷基，n是0或n是1至5的整数，并且每个X独立地表示卤素，烷基，卤代烷基，氰基烷基，烯基，炔基， 烷氧基，卤代烷氧基，卤代烷硫基，烯氧基，炔氧基，烷硫基，烯硫基，炔硫基，氰基，硝基，烷基磺酰基，烷基亚磺酰基，磺酰氨基或任选被烷基，卤代烷基，烷氧基或卤素取代的苯基。

公开(公告)号：US4988385A

公开(公告)日：1991-01-29

申请号：US357276

申请日：1989-05-26

申请人： Terence Gilkerson ,  Robert W. Shaw

发明人： Terence Gilkerson ,  Robert W. Shaw

IPC分类号： C07D213/64 ,  A01N37/34 ,  A01N37/44 ,  A01N41/06 ,  A01N41/10 ,  A01N43/40 ,  C07C65/21 ,  C07C255/40 ,  C07C255/42 ,  C07C255/43 ,  C07C255/54 ,  C07C311/29 ,  C07C317/22 ,  C07C323/20 ,  C07D213/643 ,  C07D213/69 ,  C07D213/70

CPC分类号： C07D213/643 ,  A01N37/44 ,  A01N43/40 ,  C07C255/40 ,  C07C255/43 ,  C07C255/54 ,  C07C317/22 ,  C07C323/20 ,  C07C65/21

摘要： Compounds of the general formula ##STR1## in which R.sup.1 and R.sup.2 each independently represents an alkyl group, Z represents a nitrogen atom or a group CH unsubstituted or substituted by a substituent X, m is 0 or an integer from 1 to 4, the or each Y represents a halogen atom, n is 0 or an integer from 1 to 5, and the or each X represents a halogen atom or a group selected from alkyl, haloalkyl, cyanoalkyl, alkenyl, alkynyl, alkoxy, alkenyloxy, alkynyloxy, alkylthio, alkenylthio, alkynylthio, cyano, nitro, alkylsulphonyl, alkylsulphinyl, and sulphonamido, have been found to have herbicidal activity.

公开(公告)号：US20070232593A1

公开(公告)日：2007-10-04

申请号：US11680700

申请日：2007-03-01

申请人： Terence Gilkerson ,  Roger Nash ,  Jozef Van Gestel ,  Lieven Meerpoel

发明人： Terence Gilkerson ,  Roger Nash ,  Jozef Van Gestel ,  Lieven Meerpoel

IPC分类号： A61K31/55 ,  C07D487/12

CPC分类号： C07D487/04 ,  A61K31/55 ,  A61K31/551

摘要： The present invention concerns compounds for use as a medicine having the formula the N-oxide forms, the salts, the quaternary amines and stereochemically isomeric forms thereof, wherein R1 represents hydrogen, C1-6alkyl, C1-4alkylthio, C1-4alkyloxy, or halo; R2 represents hydrogen or C1-6alkyl; R3 represents phenyl substituted with halo, cyano, C1-4alkyloxy, C1-4alkylthio, C1-6alkyl, haloC1-6alkyl; 2-thienyl; or 3-thienyl, R4 represents hydrogen; or R2 and R4 form an extra bond, which are active against dermatophytes, and their preparation; it further relates to compositions comprising them, as well as their use as a medicine.

摘要翻译： 本发明涉及用作具有N-氧化物形式的药物的化合物，其盐，季胺和立体化学异构形式，其中R 1表示氢，C 1〜 C 1 -C 6烷基，C 1-4烷基硫基，C 1-4烷基氧基或卤素; R 2表示氢或C 1-6烷基; R 3表示被卤素，氰基，C 1-4烷氧基，C 1-4烷基硫基，C 1-6烷基取代的苯基 烷基，卤代C 1-6烷基; 2-噻吩基; 或3-噻吩基，R 4表示氢; 或R 2和R 4形成对皮肤癣菌有活性的额外的结合，及其制备; 它还涉及包含它们的组合物以及它们作为药物的用途。

公开(公告)号：US4833137A

公开(公告)日：1989-05-23

申请号：US49245

申请日：1987-05-13

申请人： Terence Gilkerson ,  David C. Jennens ,  Mandy E. Coombs

发明人： Terence Gilkerson ,  David C. Jennens ,  Mandy E. Coombs

IPC分类号： A01N43/86 ,  A01P3/00 ,  C07D279/08 ,  C07D417/12 ,  C07D521/00

CPC分类号： C07D417/12 ,  A01N43/86 ,  C07D279/08

摘要： The invention provides benzothiazinone derivatives of formula ##STR1## wherein R.sub.1 represents a nitrogen-containing heteroaromatic group or a phenyl group substituted by 1 or 2 substituents selected from halogen atoms, alkyl, haloalkyl and alkoxy groups; a process for the preparation of such compounds; compositions containing them and a method of combating plant pathogenic fungi using such compositions or compounds.

摘要翻译： 本发明提供了式I的苯并噻嗪酮衍生物，其中R 1表示含氮杂芳基或被1或2个选自卤原子，烷基，卤代烷基和烷氧基的取代基取代的苯基; 一种制备这种化合物的方法; 含有它们的组合物和使用这种组合物或化合物对抗植物致病真菌的方法。

公开(公告)号：US07820650B2

公开(公告)日：2010-10-26

申请号：US11680700

申请日：2007-03-01

申请人： Terence Gilkerson ,  Roger John Nash ,  Jozef Frans Elisabetha Van Gestel ,  Lieven Meerpoel

发明人： Terence Gilkerson ,  Roger John Nash ,  Jozef Frans Elisabetha Van Gestel ,  Lieven Meerpoel

IPC分类号： A61P31/10 ,  A61K31/55 ,  C07D487/04

CPC分类号： C07D487/04 ,  A61K31/55 ,  A61K31/551

摘要： The present invention concerns compounds for use as a medicine having the formula the N-oxide forms, the salts, the quaternary amines and stereochemically isomeric forms thereof, wherein R1 represents hydrogen, C1-6alkyl, C1-4alkylthio, C1-4alkyloxy, or halo; R2 represents hydrogen or C1-6alkyl; R3 represents phenyl substituted with halo, cyano, C1-4alkyloxy, C1-4alkylthio, C1-6alkyl, haloC1-6alkyl; 2-thienyl; or 3-thienyl, R4 represents hydrogen; or R2 and R4 form an extra bond, which are active against dermatophytes, and their preparation; it further relates to compositions comprising them, as well as their use as a medicine.

摘要翻译： 本发明涉及用作具有N-氧化物形式的药物的化合物，其盐，季胺和立体化学异构形式，其中R 1表示氢，C 1-6烷基，C 1-4烷硫基，C 1-4烷氧基或卤素 ; R 2表示氢或C 1-6烷基; R 3表示被卤素，氰基，C 1-4烷氧基，C 1-4烷硫基，C 1-6烷基，卤代C 1-6烷基取代的苯基; 2-噻吩基; 或3-噻吩基，R 4表示氢; 或R2和R4形成额外的键，其对皮肤癣菌有活性，并且它们的制备; 它还涉及包含它们的组合物以及它们作为药物的用途。

公开(公告)号：US5426089A

公开(公告)日：1995-06-20

申请号：US293600

申请日：1994-08-22

申请人： Christopher J. Foster ,  Terence Gilkerson ,  Richard Stocker

发明人： Christopher J. Foster ,  Terence Gilkerson ,  Richard Stocker

IPC分类号： A01N43/40 ,  C07D213/64 ,  C07D213/643

CPC分类号： C07D213/643 ,  A01N43/40

摘要： Herbicidal compounds ##STR1## in which Q represents a group --C(O)--C(CN).dbd.CH--NR.sup.1 R.sup.2, R.sup.1 and R.sup.2 each independently represents alkyl, or together represent alkylene optionally interrupted by oxygen, m is O or m is an integer from 1 to 3 and the or each Y independently represents halogen or alkyl and n is O or n is an integer from 1 to 5 and the or each X independently represents halogen, alkyl, haloalkyl, cyanoalkyl, alkenyl, alkynyl, alkoxy, haloalkoxy, haloalkylthio, alkenyloxy, alkynyloxy, alkylthio, alkenylthio, alkynylthio, cyano, nitro, alkylsulphonyl, alkysulphinyl, sulphonamido, or phenyl optionally substituted by alkyl, haloalkyl, alkoxy or halogen.

摘要翻译： 除草剂化合物（I）其中Q代表基团-C（O）-C（CN）= CH-NR1R2，R1和R2各自独立地表示烷基，或一起表示任选被氧中断的亚烷基，m是O或 m是1至3的整数，并且每个Y独立地表示卤素或烷基，n是0或n是1至5的整数，并且每个X独立地表示卤素，烷基，卤代烷基，氰基烷基，烯基，炔基， 烷氧基，卤代烷氧基，卤代烷硫基，烯氧基，炔氧基，烷硫基，烯硫基，炔硫基，氰基，硝基，烷基磺酰基，烷基亚磺酰基，磺酰氨基或任选被烷基，卤代烷基，烷氧基或卤素取代的苯基。

公开(公告)号：US5384305A

公开(公告)日：1995-01-24

申请号：US787647

申请日：1991-11-04

申请人： Christopher J. Foster ,  Terence Gilkerson ,  Richard Stocker ,  Ian J. Gilmore

发明人： Christopher J. Foster ,  Terence Gilkerson ,  Richard Stocker ,  Ian J. Gilmore

IPC分类号： A01N43/40 ,  A01P13/00 ,  C07D213/79 ,  C07D213/81 ,  C07D213/83 ,  C07D213/86 ,  C07D213/56

CPC分类号： C07D213/79 ,  C07D213/81 ,  C07D213/83 ,  C07D213/86

摘要： Compounds of the formula ##STR1## wherein n is 1 to 5 and the/each X is hydrogen, halogen, cyano, nitro, optionally substituted alkyl or alkoxy alkenyloxy, alkynyloxy, haloalkylthio, alkenylthio or alkynylthio;m is 0 or 1 to 3 and the/each Y is halogen, alkyl or haloalkyl;Z is oxygen or sulphur;andR.sup.1 and R.sup.2 each, independently, is hydrogen, alkyl optionally substituted by halogen, hydroxy, cyano, alkoxy, alkylthio, alkoxycarbonyl, or mono- or di-alkylamino, alkenyl, alkynyl, hydroxy, alkoxy, alkenyloxy, alkynyloxy, alkoxycarbonyl, amino, mono- or di-alkylamino, alkoxycarbonylamino, arylamino, dialkylcarbamoyl, cycloalkyl, or optionally substituted cycloalkylalkyl;orR.sup.1 and R.sup.2 together form an alkylene chain optionally interrupted by oxygen, sulphur or --NR--, R being hydrogen or alkyl;are herbicides.

摘要翻译： 式（I）的化合物，其中n为1至5，并且每个X为氢，卤素，氰基，硝基，任选取代的烷基或烷氧基烯氧基，炔氧基，卤代烷硫基，烯硫基或炔硫基; m为0或1至3，并且每个Y为卤素，烷基或卤代烷基; Z是氧或硫; 羟基，氰基，烷氧基，烷硫基，烷氧基羰基或单 - 或二 - 烷基氨基，烯基，炔基，羟基，烷氧基，烯氧基，炔氧基，烷氧基羰基，氨基 ，单 - 或二 - 烷基氨基，烷氧基羰基氨基，芳基氨基，二烷基氨基甲酰基，环烷基或任选取代的环烷基烷基; 或R 1和R 2一起形成任选被氧，硫或-NR-中断的亚烷基链，R是氢或烷基; 是除草剂。

公开(公告)号：US5294597A

公开(公告)日：1994-03-15

申请号：US663722

申请日：1991-03-04

申请人： Christopher J. Foster ,  Terence Gilkerson ,  Richard Stocker

发明人： Christopher J. Foster ,  Terence Gilkerson ,  Richard Stocker

IPC分类号： A01N43/40 ,  A01P13/00 ,  C07D213/78 ,  C07D213/79 ,  C07D213/81 ,  C07D213/83 ,  C07D213/64

CPC分类号： C07D213/79 ,  A01N43/40 ,  C07D213/78 ,  C07D213/81

摘要： Compounds of formula ##STR1## wherein Z is oxygen or sulphur;R.sup.1 is hydrogen, halogen, alkyl or haloalkyl;R.sup.2 is hydrogen, or alkyl;q is 0 or 1;R.sup.3 is hydrogen, alkyl or alkenyl; the or each X independently is halogen, optionally substituted alkyl or alkoxy, alkenyloxy, alkynyloxy, cyano, carboxy, alkoxycarbonyl, (alkylthio)carbonyl, alkylcarbonyl, amido, alkylamido, nitro, alkylthio, haloalkylthio, alkenylthio, alkynylthio, alkylsulphinyl, alkylsulphonyl, alkyloximinoalkyl or alkenyloximinoalkyl;n is 0 or an integer from 1 to 5; the or each Y independently is a halogen, alkyl, nitro, cyano, haloalkyl, alkoxy or haloalkoxy; and m is 0 or an integer from 1 to 5, their preparation and use as herbicides.

摘要翻译： 式（*化学结构*）（I）的化合物，其中Z是氧或硫; R1是氢，卤素，烷基或卤代烷基; R2是氢或烷基; q为0或1; R3是氢，烷基或烯基; 氰基，羧基，烷氧基羰基，（烷硫基）羰基，烷基羰基，酰胺基，烷基酰氨基，硝基，烷硫基，卤代烷硫基，烯硫基，炔硫基，烷基亚磺酰基，烷基磺酰基，烷氧基亚氨基烷基 或烯氧肟基烷基; n为0或1〜5的整数; 该或每个Y独立地是卤素，烷基，硝基，氰基，卤代烷基，烷氧基或卤代烷氧基; m为0或1〜5的整数，它们的制备和用作除草剂。

公开(公告)号：US4954160A

公开(公告)日：1990-09-04

申请号：US247273

申请日：1988-09-21

申请人： Terence Gilkerson ,  Robert W. Shaw

发明人： Terence Gilkerson ,  Robert W. Shaw

IPC分类号： C07D251/64 ,  A01N33/16 ,  A01N33/24 ,  A01N35/10 ,  A01N41/06 ,  A01N43/30 ,  A01P13/00 ,  C07C45/45 ,  C07C45/54 ,  C07C49/657 ,  C07C49/697 ,  C07C49/747 ,  C07C49/753 ,  C07C67/00 ,  C07C239/00 ,  C07C251/42 ,  C07C251/44 ,  C07C251/52 ,  C07C301/00 ,  C07C303/28 ,  C07C311/29 ,  C07D317/54 ,  C07D317/58

CPC分类号： C07C49/657 ,  A01N35/10 ,  A01N41/06 ,  A01N43/30 ,  C07C45/455 ,  C07C45/54 ,  C07C49/697 ,  C07C49/747 ,  C07C49/753 ,  C07D317/54

摘要： The invention provides compounds of the general formula ##STR1## wherein R represents a hydrogen atom, or an optionally substituted alkyl or acyl group, or an alkenyl or alkynyl group or an inorganic or organic cation;R.sup.1 represents an alkyl, haloalkyl, alkenyl, alkynyl or optionally substituted aralkyl or phenyl group;R.sup.2 represents an optionally substituted alkyl or phenalkyl group or a cycloalkyl, alkenyl, haloalkenyl or alkynyl group;each R.sup.3 represents an optionally substituted alkyl group;one of R.sup.4 or R.sup.5 represents a hydrogen atom or an alkyl group while the other of R.sup.4 and R.sup.5 represents an optionally substituted phenyl group; together with their use as herbicides and their preparation using novel intermediates.

公开(公告)号：US07202240B2

公开(公告)日：2007-04-10

申请号：US10399596

申请日：2001-10-17

申请人： Terence Gilkerson ,  Roger John Nash ,  Jozel Frans Elisabetha Van Gestel ,  Lieven Meerpoel

发明人： Terence Gilkerson ,  Roger John Nash ,  Jozel Frans Elisabetha Van Gestel ,  Lieven Meerpoel

IPC分类号： A61K31/55 ,  A61P31/10 ,  C07D487/04

CPC分类号： C07D487/04 ,  A61K31/55 ,  A61K31/551

摘要： The present invention concerns compounds for use as a medicine having the formula (I), the N-oxide forms, the salts, the quaternary amines and stereochemically isomeric forms thereof, wherein R1 represents hydrogen, C1-6 alkyl, C1-4alkylthio, C1-4alkyloxy, or halo; R2 represents hydrogen or C1-6alkyl; R3 represents phenyl substituted with halo, cyano, C1-4alkyloxy, C1-4alkylthio, C1-6alkyl, haloC1-6alkyl; 2-thienyl; or 3-thienyl, R4 represents hydrogen; or R2 and R4 form an extra bond, which are active against dermatophytes, and their preparation; it further relates to compositions comprising them, as well as their use as a medicine.

摘要翻译： 本发明涉及用作具有式（I）的药物，N-氧化物形式，其盐，季胺及其立体化学异构形式的化合物，其中R 1表示氢， C 1-4烷基，C 1-4烷基硫基，C 1-4烷基氧基或卤素; R 2表示氢或C 1-6烷基; R 3表示被卤素，氰基，C 1-4烷氧基，C 1-4烷基硫基，C 1-6烷基取代的苯基 烷基，卤代C 1-6烷基; 2-噻吩基; 或3-噻吩基，R 4表示氢; 或R 2和R 4形成对皮肤癣菌有活性的额外的结合，及其制备; 它还涉及包含它们的组合物以及它们作为药物的用途。