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公开(公告)号:US20230302045A1
公开(公告)日:2023-09-28
申请号:US18004940
申请日:2021-06-14
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor: Semra Colak Atan , Hannah C. Cohen , Max A. Kruziki , Ranjani V. Parthasarathy , Matthew T. Scholz
Abstract: Medical compositions and methods of suppressing microbial virulence are provided. By suppressing virulence, administration and/or application of the medical compositions can be used to prevent, mitigate, or treat a microbial infection. More specifically, the medical compositions include a phosphonate-containing polymer. The phosphonate-containing polymers can suppress the expression of various virulence factors without destroying all microbes that may be present.
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公开(公告)号:US20220003904A1
公开(公告)日:2022-01-06
申请号:US17280447
申请日:2019-09-25
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor: Timothy J. Hebrink , Stephen P. Maki , Charles D. Hoyle , Joel D. Oxman , Matthew T. Scholz , Justin M. Mazzoni , Michael E. Griffin , Anna C. Hamlin
Abstract: Multilayer optical film comprising at least a plurality of alternating first and second optical layers. Embodiments of the multilayer optical film are useful, for example, in UV-C shield, UV-C light collimator, and UV-C light concentrator applications.
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公开(公告)号:US10682830B2
公开(公告)日:2020-06-16
申请号:US14892096
申请日:2014-06-02
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor: Steven P. Swanson , Semra Colak Atan , Onur S. Yordem , Stephen A. Johnson , Timothy J. Lindquist , Terence D. Neavin , Matthew T. Scholz
IPC: B32B7/06 , B32B27/08 , B32B27/18 , B32B3/06 , B32B3/02 , B32B3/26 , B32B27/32 , B32B27/36 , B32B38/10 , A01N25/34
Abstract: Multilayered polymer films are configured so that successive constituent layer packets can be delaminated in continuous sheet form from the remaining film. The films are compatible with known coextrusion manufacturing techniques, and can be made without adhesive layers between layer packets that are tailored to be individually peelable from the remainder of the film. Instead, combinations of polymer compositions are used to allow non-adhesive polymer layers to be combined such that irreversible delamination of the film is likely to occur at interfaces between layer packets pairs. Some of the polymer layers, including at least one embedded layer, comprise an antimicrobial agent, and these layers may be positioned at the front of each layer packet. After the antimicrobial layer of one layer packet has been used, the packet can be peeled away to expose a pristine antimicrobial layer of the next layer packet. The antimicrobial agent may be organic.
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公开(公告)号:US10555889B2
公开(公告)日:2020-02-11
申请号:US15736853
申请日:2016-06-27
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor: Ranjani V. Parthasarathy , Ramesh C. Kumar , Matthew T. Scholz , Steven P. Swanson , Erin A. Satterwhite
IPC: A61K8/81 , A01N25/10 , A01N31/02 , A01N33/12 , A01N37/02 , A01N43/40 , A01N43/44 , A01N47/44 , A61K8/49 , A61K8/43 , A61L2/00 , A61Q17/00 , A61K8/34 , A61K8/41
Abstract: Disclosed herein are compositions that include at least about 85 wt % of a hydroalcoholic solution that includes at least about 1 wt % water; and about 30 to about 85 wt % of at least one C1 to C4 alkyl alcohol based on the total weight of the hydroalcoholic solution; and acrylate copolymer particles dispersed in the hydroalcoholic solution, the acrylate copolymers particles being the reaction product of a reaction mixture, the reaction mixture including monomers, the monomers including from about 5 wt % to about 50 wt % of at least one high Tg monomer; and from about 20 w % to about 80 wt % of at least one low Tg monomer where the wt % of the low and high Tg monomers are with respect to the total weight of the monomers in the reaction mixture, wherein the particles have a number average diameter of at least about 100 nm.
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公开(公告)号:US10471036B2
公开(公告)日:2019-11-12
申请号:US13942122
申请日:2013-07-15
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor: Matthew T. Scholz , Dianne L. Gibbs , John T. Capecchi , Jeffrey F. Andrews
IPC: A61K31/23 , A61K9/00 , A61K31/19 , A61K31/231 , A61K31/25 , A61K45/06 , A61K47/06 , A61K47/10 , A61K47/12 , A61K47/14 , A61K47/20 , A61K47/44
Abstract: Antimicrobial compositions, especially those useful when applied topically, particularly to mucosal tissues (i.e., mucous membranes), including, in particular, an antimicrobial lipid component, such as a fatty acid ester, fatty ether, or alkoxide derivative thereof. The compositions can also include an enhancer component, a surfactant, a hydrophobic component, and/or a hydrophilic component. Such compositions provide effective topical antimicrobial activity and are accordingly useful in the treatment and/or prevention of conditions that are caused, or aggravated by, microorganisms (including viruses).
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公开(公告)号:US20190275191A1
公开(公告)日:2019-09-12
申请号:US16343652
申请日:2017-10-05
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor: Junkang Jacob Liu , Ta-Hua Yu , Amy K. McNulty , Narina Y. Stepanova , Badri Veeraraghavan , Eric J. Olson , Matthew T. Scholz , Ranjani V. Parthasarathy , Kevin D. Hagen
Abstract: An article having anti-microbial effect is provided. The article includes an occlusive layer; a substrate overlaying the occlusive layer, wherein the substrate having two opposing major surfaces; a metal oxide layer overlaying one opposing major surface of the substrate, wherein the metal oxide layer comprises a metal oxide; and a metal layer overlaying the other opposing major surface of the substrate; wherein the substrate is between the metal oxide layer and the metal layer; and wherein electric potential of the metal oxide layer is at least 0.454V more than electric potential of the metal layer.
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公开(公告)号:US20190000436A1
公开(公告)日:2019-01-03
申请号:US16104257
申请日:2018-08-17
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor: Adolfo Llinas , Stephen E. Krampe , Matthew T. Scholz , Patrick J. Parks
IPC: A61B17/02 , A61F13/00 , A61B90/00 , A61F13/02 , A61B46/00 , A61B17/00 , A61B90/40 , A61B46/20 , A61F13/45 , A61F13/15
Abstract: Methods and products for protecting tissue of a patient during a surgical procedure that involve making an incision in the tissue and retracting the tissue to make a larger opening, wherein the methods and products use a water-absorbing stress-distributing layer.
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公开(公告)号:US10138576B2
公开(公告)日:2018-11-27
申请号:US14487134
申请日:2014-09-16
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor: Matthew T. Scholz , Francis E. Porbeni , Jay M. Jennen , Korey W. Karls
IPC: D01F6/62 , A61L15/26 , A61L15/46 , A61L15/48 , C08L67/02 , C08L67/04 , D01F1/10 , A01N25/30 , A41D13/12 , B29C39/00 , B29C44/00 , A61L31/04 , D04H1/435 , D04H1/4382 , A61B46/00 , C08K5/053 , C08K5/098 , C08K5/103 , C08K5/41 , C08K5/42 , C08K5/51 , C08L71/02
Abstract: Durable hydrophilic compositions comprising aliphatic polyester, an anionic surfactant, and in some embodiments, a carrier.
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公开(公告)号:US09468614B2
公开(公告)日:2016-10-18
申请号:US13893694
申请日:2013-05-14
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor: Katie F. Wlaschin , Alan R. Dombrowski , Matthew T. Scholz , Ranjani V. Parthasarathy
IPC: A61K31/155 , A61M16/04
CPC classification number: A61K31/155 , A61M16/04
Abstract: A method of moisturizing while decolonizing mammalian tissue, comprising applying a multi-valent cationic antiseptic composition to the tissue, and applying a moisturizer composition to at least a portion of the same tissue is provided. An oral care kit comprising a composition comprising the multi-valent cationic antiseptic and the moisturizer composition, and a method of moisturizing oral tissue of a patient requiring intubation using the moisturizer composition and an endotracheal tube coated or impregnated with a cationic antiseptic are also provided.
Abstract translation: 提供了使哺乳动物组织非殖化时保湿的方法,其包括将多价阳离子防腐组合物施用于组织,以及将保湿组合物施用于相同组织的至少一部分。 还提供了包含含有多价阳离子防腐剂和保湿组合物的组合物的口腔护理试剂盒,以及使用保湿组合物对需要插管的患者的口腔组织进行润湿的方法以及涂敷或浸渍阳离子防腐剂的气管内管。
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公开(公告)号:US20150094368A1
公开(公告)日:2015-04-02
申请号:US14556310
申请日:2014-12-01
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor: Matthew T. Scholz , Terry R. Hobbs , DanLi Wang
IPC: A61K31/23 , A61K31/155
CPC classification number: A61K31/23 , A61K9/0034 , A61K9/0043 , A61K31/00 , A61K31/155 , A61K33/42 , A61K45/06 , Y02A50/473
Abstract: Methods of delaying the onset of an infection or preventing an infection caused by a microbial organism in an internal cavity of a subject are provided. Methods of killing or inactivating microorganisms in at least a portion of the urethra of a subject are provided.
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