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公开(公告)号：US20240082507A1
公开(公告)日：2024-03-14
申请号：US17767462
申请日：2020-10-07
Applicant: AMGEN INC.
Inventor： Samin Akbari , Azita Rahbari , Sunitha Dasoju , Andrew Coles , Jerome Olivas , Michele Macchi , Desheng Yin , Harpreet Sachar , Alireza Ashani , Angelo Tosarini , Antonio Antonini
IPC: A61M5/32
CPC classification number: A61M5/3257 , A61M5/3213
Abstract: A cassette for a drug delivery device is described that includes a sleeve, a syringe having a barrel disposed in the sleeve, and a plunger-stopper slidably disposed within the barrel. The cassette further includes a spacer that is configured to be coupled to the sleeve. The cassette can form a part of an apparatus for injection of a therapeutic product along with a drug delivery device.
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公开(公告)号：US20240100247A1
公开(公告)日：2024-03-28
申请号：US17767466
申请日：2020-10-01
Applicant: AMGEN INC.
Inventor： Tohid Pirbodaghi , Joshua Tamsky , Paul Daniel Faucher , Jeff Lind , Scott R. Gibson , Sheldon B. Moberg , Samin Akbari
CPC classification number: A61M5/14248 , A61M5/1454 , A61M5/16881 , A61M39/26 , A61M2005/14252
Abstract: A drug delivery device includes a housing, a container disposed in the housing, an activation mechanism, a needle insertion mechanism, and a fluid flow path. The container has an inner volume to contain a medicament which is urged out of the container by the activation mechanism. The needle insertion mechanism includes an actuation assembly adapted to insert a needle and a cannula to deliver the medicament from the container and a valve assembly. The fluid flow connection is coupled with the container and the needle insertion mechanism and is adapted to allow the medicament to flow from the container to the needle insertion mechanism. The valve assembly is repeatedly movable between at least a valve open position and a valve closed position to selectively allow and restrict the medicament to flow through the needle and/or the cannula.
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公开(公告)号：US20220355025A1
公开(公告)日：2022-11-10
申请号：US17641458
申请日：2020-10-05
Applicant: AMGEN INC.
Inventor： Tohid Pirbodaghi , Samin Akbari , Joshua Tamsky , Paul Daniel Faucher , Scott Robert Gibson , Sheldon B. Moberg
Abstract: A drug delivery device includes a housing, a container disposed in the housing, an activation mechanism, and a needle insertion mechanism (NIM). The container has an inner volume to contain a medicament which is urged out of the container by the activation mechanism. The needle insertion mechanism (NIM) is operably coupled with the activation mechanism and includes an actuation assembly adapted to insert a needle and a cannula to deliver the medicament from the container. The actuation assembly is movable between a storage state, a first operational state, a second operational state, and a third operational state to selectively position the needle and the cannula.
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Patent Agency Ranking
公开(公告)号：US20230355895A1
公开(公告)日：2023-11-09
申请号：US17911510
申请日：2021-02-08
Applicant: AMGEN INC.
Inventor： Samin Akbari , Paul Daniel Faucher
CPC classification number: A61M5/36 , A61M5/31505 , A61M5/3146 , A61M2005/31508
Abstract: A syringe is described with a plunger assembly that is adapted to have a dispensing stroke sized to dispense a fluid therapeutic product from the syringe without dispensing any air or headspace. The syringe includes a plunger rod having a stop feature that stops a dispensing stroke of the plunger rod at a distance corresponding to a level of air or headspace within the syringe avoiding additional air dispensing steps from a healthcare provider.
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公开(公告)号：US20210316075A1
公开(公告)日：2021-10-14
申请号：US17196744
申请日：2021-03-09
Applicant: AMGEN INC
Inventor： Samin Akbari , Tohid Pirbodaghi , Sheldon B. Moberg
Abstract: Drug delivery devices and associated heating and/or cooling devices are disclosed. In an example, a drug delivery device includes a housing, a container, a therapy layer, and a first adhesive layer. The housing includes a top wall and a bottom wall. The container is at least partially disposed within the housing. The container has an inner volume to contain a drug. The therapy layer have a first side and a second side. The first side faces the bottom wall and the second side faces away from the bottom wall. The first adhesive layer couples the first side of the therapy layer and the bottom wall. The therapy layer is adapted to at least one of heat or cool an area adjacent an injection site.
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公开(公告)号：US12194280B2
公开(公告)日：2025-01-14
申请号：US17196744
申请日：2021-03-09
Applicant: AMGEN INC.
Inventor： Samin Akbari , Tohid Pirbodaghi , Sheldon B. Moberg
Abstract: Drug delivery devices and associated heating and/or cooling devices are disclosed. In an example, a drug delivery device includes a housing, a container, a therapy layer, and a first adhesive layer. The housing includes a top wall and a bottom wall. The container is at least partially disposed within the housing. The container has an inner volume to contain a drug. The therapy layer have a first side and a second side. The first side faces the bottom wall and the second side faces away from the bottom wall. The first adhesive layer couples the first side of the therapy layer and the bottom wall. The therapy layer is adapted to at least one of heat or cool an area adjacent an injection site.
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公开(公告)号：US11890450B2
公开(公告)日：2024-02-06
申请号：US16297408
申请日：2019-03-08
Applicant: AMGEN INC.
Inventor： Lawrence Scott Ring , Tohid Pirbodaghi , Samin Akbari , Daniel Eduardo Groszmann , Mehran Mojarrad , Mark Gordon , Mikhail Tikh , Jimmie L. Ward , Scott R. Gibson , Sheldon B. Moberg , Joshua Tamsky , Paul Faucher , Jeff Lind
CPC classification number: A61M5/16813 , A61M5/1413 , A61M5/14248 , A61M5/158 , A61M5/16822 , A61M39/24 , A61M5/14526 , A61M5/155 , A61M2005/1403 , A61M2005/1406 , A61M2005/14252 , A61M2039/244 , A61M2039/2406 , A61M2039/248 , A61M2039/2426 , A61M2205/3561 , A61M2205/505 , A61M2205/7527 , A61M2205/7536 , A61M2209/045
Abstract: A drug delivery device includes a housing defining a shell and an inner volume, a container, a drive mechanism, a needle assembly, a fluid flow connection, and a backflow prevention mechanism. The container has an inner volume to contain a medicament to be administered to a user. The drive mechanism is at least partially disposed within the housing and exerts a force to urge the medicament out the container. The fluid flow connection is coupled to the container and the needle assembly and allows the medicament to flow from the container to the needle assembly to be administered. The backflow prevention mechanism is associated with at least one of the container, the fluid flow connection, or the needle assembly and includes at least one flow restrictor to restrict a fluid from flowing from the needle assembly to the container.
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公开(公告)号：US20190275241A1
公开(公告)日：2019-09-12
申请号：US16297408
申请日：2019-03-08
Applicant: AMGEN INC.
Inventor： Lawrence S. Ring , Tohid Pirbodaghi , Samin Akbari , Daniel Eduardo Groszmann , Mehran Mojarrad , Mark Gordon , Mikhail Tikh , Jimmie L. Ward , Scott R. Gibson , Sheldon B. Moberg , Joshua Tamsky , Paul Faucher
Abstract: A drug delivery device includes a housing defining a shell and an inner volume, a container, a drive mechanism, a needle assembly, a fluid flow connection, and a backflow prevention mechanism. The container has an inner volume to contain a medicament to be administered to a user. The drive mechanism is at least partially disposed within the housing and exerts a force to urge the medicament out the container. The fluid flow connection is coupled to the container and the needle assembly and allows the medicament to flow from the container to the needle assembly to be administered. The backflow prevention mechanism is associated with at least one of the container, the fluid flow connection, or the needle assembly and includes at least one flow restrictor to restrict a fluid from flowing from the needle assembly to the container.
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