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1.发明申请PRESSURE-SENSITIVE ADHESIVE COMPOSITION APPLICABLE TO NAIL AND ADHESIVE AGENT FOR NAIL 审中-公开适用于指甲和粘合剂的压敏粘合剂组合物公开(公告)号：US20100178321A1
公开(公告)日：2010-07-15
申请号：US12729675
申请日：2010-03-23
申请人： Akinori HANATANI , Hitoshi Akemi
发明人： Akinori HANATANI , Hitoshi Akemi
CPC分类号： A61K8/0208 , A61K8/02 , A61K8/891 , A61Q3/00 , C08L83/00 , C08L2666/02 , C09J183/04
摘要： The present invention aims at providing a pressure-sensitive adhesive composition applicable to nail, which shows superior adhesive performance (adhesive force, cohesion etc.), and superior drug releasability and drug stability, and an adhesive agent for nail, which uses this composition. The composition of the present invention contains a condensation polymer of a silicone resin and a silicone rubber. The composition of the present invention preferably contains not less than two kinds of condensation polymers having different resin/rubber ratios. The adhesive agent of the present invention has a support and an adhesive layer formed on one surface of the support, which contains the above-mentioned composition.
摘要翻译： 本发明的目的在于提供一种适用于指甲的压敏粘合剂组合物，其具有优异的粘合性能（粘合力，内聚力等）和优异的药物释放性和药物稳定性，以及使用该组合物的指甲粘合剂。 本发明的组合物含有有机硅树脂和硅橡胶的缩聚物。 本发明的组合物优选含有不少于两种具有不同树脂/橡胶比的缩聚物。 本发明的粘合剂具有形成在载体的一个表面上的载体和粘合剂层，其包含上述组合物。
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公开(公告)号：US20100010043A1
公开(公告)日：2010-01-14
申请号：US12475249
申请日：2009-05-29
IPC分类号： A61K31/445 , C07D211/08
CPC分类号： A61K31/4465 , A61K9/7053 , A61K9/7061
摘要： The present invention provides a percutaneously absorbable preparation comprising 2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one and/or a hydrochloride thereof wherein the percuneously absorbable preoaration is able to administer to a patient such that Cmax per unit surface area of the percutaneously absorbable preparation is 0.025 to 0.5 ng/ml·cm2 in a plasma concentration profile.
摘要翻译： 本发明提供了包含2 - [（1-苄基哌啶-4-基）甲基] -5,6-二甲氧基茚满-1-酮和/或其盐酸盐的经皮吸收制剂，其中可以吸收的预制剂能够施用于 使得经皮吸收制剂的每单位表面积的C max在血浆浓度分布中为0.025至0.5ng / ml.cm 2。
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公开(公告)号：US08033395B2
公开(公告)日：2011-10-11
申请号：US12314564
申请日：2008-12-12
摘要： The main object of the present invention is to provide a patch package structure including a patch containing a physiologically active ingredient and a package housing the patch, which is capable of stably retaining the physiologically active ingredient in the patch during preservation. This object can be achieved by employing the following constitution.To be specific, the present invention is a patch package structure including a patch 1 having an adhesive layer containing an organic liquid component, and a packaging member 51 housing the patch, wherein the packaging member 51 includes a first package 11, the first package 11 including an acrylonitrile resin layer 12, a moisture-absorbing layer 13 formed on the acrylonitrile resin layer 12, and a moisture impermeable layer 14 formed on the moisture-absorbing layer 13, and the acrylonitrile resin layer 12 is provided on the proximal side of the patch 1.
摘要翻译： 本发明的主要目的是提供一种贴片包装结构，其包括含有生理活性成分的贴剂和容纳该贴剂的包装，其能够在保存期间稳定地保留贴剂中的生理活性成分。 该目的可以通过采用以下结构来实现。 具体而言，本发明是一种贴片包装结构，其包括具有含有有机液体成分的粘合剂层的贴片1和容纳该贴片的包装部件51，其中，包装部件51包括第一包装体11，第一包装体11 包括丙烯腈树脂层12，形成在丙烯腈树脂层12上的吸湿层13和形成在吸湿层13上的不透水层14和丙烯腈树脂层12设置在 补丁1。
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公开(公告)号：US07501358B2
公开(公告)日：2009-03-10
申请号：US11402004
申请日：2006-04-12
申请人： Junichi Saito , Akinori Hanatani , Hitoshi Akemi
发明人： Junichi Saito , Akinori Hanatani , Hitoshi Akemi
IPC分类号： B32B27/04
CPC分类号： A61K9/7061 , Y10T442/20 , Y10T442/2738 , Y10T442/2754
摘要： The present invention provides an adhesive preparation superior in adhesion property, which does not peel off or fall off easily and which can be adhered for a long time. An adhesive preparation 10 has a support 1 made of a cloth, and a pressure sensitive adhesive layer 3 formed on one surface of the support 1, which contains a pressure sensitive adhesive and a drug. The ratio (CW/AW) of a mass (CW) per unit area of the support 1 and a mass (AW) per unit area of the pressure sensitive adhesive layer 3 is 1.0-5.0, an adhesive layer-free surface of the support 1 has a static friction coefficient of 0.25-0.75, and a 20% modulus (AM) in one direction of the adhesive preparation 10 and a 20% modulus (EM) in the direction perpendicular to that direction are each 0.5-1.5 N/cm, and the ratio thereof (AM/EM) is 0.5-2.0.
摘要翻译： 本发明提供一种粘合性优异的粘合剂，其不会容易地剥离或脱落，并且可以长时间粘合。 粘合剂10具有由布制成的支撑体1和形成在载体1的一个表面上的压敏粘合剂层3，该粘合剂层3含有压敏粘合剂和药物。 支撑体1的每单位面积的质量（CW）的比（CW / AW）和压敏粘合剂层3的每单位面积的质量（AW）为1.0-5.0，载体的无粘合剂层的表面 1具有0.25-0.75的静摩擦系数，粘合剂10的一个方向上的20％模量（AM）和与该方向垂直的方向上的20％模量（EM）分别为0.5-1.5N / cm ，其比例（AM / EM）为0.5〜2.0。
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公开(公告)号：US20060234581A1
公开(公告)日：2006-10-19
申请号：US11402004
申请日：2006-04-12
申请人： Junichi Saito , Akinori Hanatani , Hitoshi Akemi
发明人： Junichi Saito , Akinori Hanatani , Hitoshi Akemi
CPC分类号： A61K9/7061 , Y10T442/20 , Y10T442/2738 , Y10T442/2754
摘要： The present invention provides an adhesive preparation superior in adhesion property, which does not peel off or fall off easily and which can be adhered for a long time. An adhesive preparation 10 has a support 1 made of a cloth, and a pressure sensitive adhesive layer 3 formed on one surface of the support 1, which contains a pressure sensitive adhesive and a drug. The ratio (CW/AW) of a mass (CW) per unit area of the support 1 and a mass (AW) per unit area of the pressure sensitive adhesive layer 3 is 1.0-5.0, an adhesive layer-free surface of the support 1 has a static friction coefficient of 0.25-0.75, and a 20% modulus (AM) in one direction of the adhesive preparation 10 and a 20% modulus (EM) in the direction perpendicular to that direction are each 0.5-1.5 N/cm, and the ratio thereof (AM/EM) is 0.5-2.0.
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公开(公告)号：US09040077B2
公开(公告)日：2015-05-26
申请号：US12656700
申请日：2010-02-12
CPC分类号： A61K9/703 , A61F2013/00651 , A61K9/7061
摘要： The present invention provides to a patch and a patch preparation having low stretchability, which can be continuously adhered to the skin for a long time without undesirable detachment and marked falling off from the skin due to various factors during adhesion, and specifically provides a low stretchable patch and a patch preparation containing a support and an adhesive layer formed on one surface of the support, wherein a ratio P of the total length W (mm) of curved sections of a planar outer shape of the patch to the total length S (mm) of straight-line sections of the planar outer shape of the patch (W/S) is not more than 1.22, and, when the curved sections are approximated by a circular arc, the radius R (mm) of the circular arc is not less than 0.5 mm.
摘要翻译： 本发明提供一种具有低拉伸性的贴剂和贴片制剂，其可以在粘合期间由于各种因素而长时间连续地粘附到皮肤上而没有不希望的分离并且从皮肤上显着脱落，并且具体地提供了低伸缩性 贴片和贴片制剂，其包含支撑体和形成在支撑体的一个表面上的粘合剂层，其中贴片平面外形的弯曲部分的总长度W（mm）与总长度S（mm）之比P （W / S）的平面外形的直线部分的面积不大于1.22，并且当弯曲部分被圆弧近似时，圆弧的半径R（mm）不是 小于0.5毫米。
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公开(公告)号：US20110056863A1
公开(公告)日：2011-03-10
申请号：US12990818
申请日：2009-05-26
IPC分类号： B65D85/00 , A61K9/70 , A61K31/445 , A61P25/28
CPC分类号： A61K9/7061 , A61K31/4465 , B65D81/24
摘要： [Object] An adhesive preparation containing donepezil is provided in which adhesive layer discoloration over time is inhibited.[Solution] The adhesive preparation containing donepezil has an adhesive layer containing donepezil and an acrylic adhesive on at least one side of a support, and a water content of the adhesive layer is 1000 ppm or more. The water content of the adhesive layer is preferably 8000 ppm or less and more preferably 7000 ppm or less.
摘要翻译： 提供了含有多奈哌齐的粘合剂，其中粘合剂层随着时间的变色被抑制。 [解决方案]含有多奈哌齐的粘合剂在载体的至少一侧上具有含有多奈哌齐和丙烯酸类粘合剂的粘合剂层，粘合剂层的含水量为1000ppm以上。 粘合剂层的含水量优选为8000ppm以下，更优选为7000ppm以下。
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公开(公告)号：US20100203108A1
公开(公告)日：2010-08-12
申请号：US12656700
申请日：2010-02-12
CPC分类号： A61K9/703 , A61F2013/00651 , A61K9/7061
摘要： The present invention provides to a patch and a patch preparation having low stretchability, which can be continuously adhered to the skin for a long time without undesirable detachment and marked falling off from the skin due to various factors during adhesion, and specifically provides a low stretchable patch and a patch preparation containing a support and an adhesive layer formed on one surface of the support, wherein a ratio P of the total length W (mm) of curved sections of a planar outer shape of the patch to the total length S (mm) of straight-line sections of the planar outer shape of the patch (W/S) is not more than 1.22, and, when the curved sections are approximated by a circular arc, the radius R (mm) of the circular arc is not less than 0.5 mm.
摘要翻译： 本发明提供一种具有低拉伸性的贴剂和贴片制剂，其可以在粘合期间由于各种因素而长时间连续地粘附到皮肤上而没有不希望的分离并且从皮肤上显着脱落，并且具体地提供了低伸缩性 贴片和贴片制剂，其包含支撑体和形成在支撑体的一个表面上的粘合剂层，其中贴片平面外形的弯曲部分的总长度W（mm）与总长度S（mm）之比P （W / S）的平面外形的直线部分的面积不大于1.22，并且当弯曲部分被圆弧近似时，圆弧的半径R（mm）不是 小于0.5毫米。
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9.发明申请Pressure-sensitive adhesive composition applicable to nail and adhesive agent for nail 审中-公开用于钉子的指甲和粘合剂的压敏粘合剂组合物公开(公告)号：US20090047333A1
公开(公告)日：2009-02-19
申请号：US12285606
申请日：2008-10-09
申请人： Akinori Hanatani , Hitoshi Akemi
发明人： Akinori Hanatani , Hitoshi Akemi
IPC分类号： A61K9/70
CPC分类号： A61K8/0208 , A61K8/02 , A61K8/891 , A61Q3/00 , C08L83/00 , C08L2666/02 , C09J183/04
摘要： The present invention aims at providing a pressure-sensitive adhesive composition applicable to nail, which shows superior adhesive performance (adhesive force, cohesion etc.), and superior drug releasability and drug stability, and an adhesive agent for nail, which uses this composition. The composition of the present invention contains a condensation polymer of a silicone resin and a silicone rubber. The composition of the present invention preferably contains not less than two kinds of condensation polymers having different resin/rubber ratios. The adhesive agent of the present invention has a support and an adhesive layer formed on one surface of the support, which contains the above-mentioned composition.
摘要翻译： 本发明的目的在于提供一种适用于指甲的压敏粘合剂组合物，其具有优异的粘合性能（粘合力，内聚力等）和优异的药物释放性和药物稳定性，以及使用该组合物的指甲粘合剂。 本发明的组合物含有有机硅树脂和硅橡胶的缩聚物。 本发明的组合物优选含有不少于两种具有不同树脂/橡胶比的缩聚物。 本发明的粘合剂具有形成在载体的一个表面上的载体和粘合剂层，其含有上述组合物。
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公开(公告)号：US08096417B2
公开(公告)日：2012-01-17
申请号：US12314563
申请日：2008-12-12
CPC分类号： A61F15/001 , A61L15/24 , C08L33/20
摘要： The main object of the present invention is to provide a patch package structure capable of stably retaining the physiologically active ingredient in a patch during preservation of the patch. This object can be achieved by employing the following constitution.To be specific, the present invention is a patch package structure including a patch 1 and a packaging member 51 holding the patch, wherein the patch 1 includes a support 2 and an adhesive layer 3 formed on at least one surface of the support 2, the packaging member 51 includes a first package 11, the first package 11 including an acrylonitrile resin layer 12, a moisture-absorbing layer 13 formed on the acrylonitrile resin layer 12, and a moisture impermeable layer 14 formed on the moisture-absorbing layer 13, and the acrylonitrile resin layer 12 is provided on the proximal side of the patch 1.
摘要翻译： 本发明的主要目的是提供一种贴片包装结构，其能够在贴片保存期间将贴片的生理活性成分稳定地保持。 该目的可以通过采用以下结构来实现。 具体而言，本发明是一种贴片包装结构，其包括贴片1和保持贴片的包装部件51，其中贴片1包括形成在支撑体2的至少一个表面上的支撑体2和粘合剂层3， 包装部件51包括第一包装11，包含丙烯腈树脂层12的第一包装11，形成在丙烯腈树脂层12上的吸湿层13和形成在吸湿层13上的不透水层14，以及 丙烯腈树脂层12设置在贴剂1的近侧。
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