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公开(公告)号：US20060020008A1
公开(公告)日：2006-01-26
申请号：US11154989
申请日：2005-06-15
申请人： Andrew McDonald , Gustave Bergnes , Bainian Feng , David Morgans , Steven Knight , Kenneth Newlander , Dashyant Dhanak , Christopher Brook
发明人： Andrew McDonald , Gustave Bergnes , Bainian Feng , David Morgans , Steven Knight , Kenneth Newlander , Dashyant Dhanak , Christopher Brook
IPC分类号： A61K31/4178 , C07D405/02
CPC分类号： C07D405/06 , C07D311/22 , C07D311/36 , C07D405/12 , C07D407/12 , C07D409/12 , C07D413/12 , C07D417/12
摘要： Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of KSP are disclosed.
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公开(公告)号：US20060094735A1
公开(公告)日：2006-05-04
申请号：US11262506
申请日：2005-10-27
申请人： Bainian Feng , Gustave Bergnes , David Morgans , Dashyant Dhanak , Steven Knight , Michael Darcy
发明人： Bainian Feng , Gustave Bergnes , David Morgans , Dashyant Dhanak , Steven Knight , Michael Darcy
IPC分类号： A61K31/517 , C07D403/02
CPC分类号： C07D403/06
摘要： Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of KSP are disclosed.
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公开(公告)号：US20070254870A1
公开(公告)日：2007-11-01
申请号：US11788784
申请日：2007-04-19
申请人： Gustave Bergnes , Dashyant Dhanak , Steven Knight , Pu Lu , David Morgans , Kenneth Newlander
发明人： Gustave Bergnes , Dashyant Dhanak , Steven Knight , Pu Lu , David Morgans , Kenneth Newlander
IPC分类号： A61K31/551 , C07D243/00 , C12N9/99
CPC分类号： C07D403/06
摘要： Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of KSP are disclosed.
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公开(公告)号：US20070135432A1
公开(公告)日：2007-06-14
申请号：US11600683
申请日：2006-11-15
申请人： Han-Jie Zhou , David Morgans , Gustave Bergnes , Steven Knight , Kenneth Newlander , Dashyant Dhanak , Nicholas Adams
发明人： Han-Jie Zhou , David Morgans , Gustave Bergnes , Steven Knight , Kenneth Newlander , Dashyant Dhanak , Nicholas Adams
IPC分类号： C07D413/02 , C07D403/02 , A61K31/5377 , A61K31/513
CPC分类号： C07D239/36 , C07D231/12 , C07D233/56 , C07D239/47 , C07D239/91 , C07D249/08 , C07D403/06
摘要： Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of KSP are disclosed.
摘要翻译： 公开了通过调节KSP的活性来治疗细胞增殖性疾病和病症的化合物。
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公开(公告)号：US20060052360A1
公开(公告)日：2006-03-09
申请号：US10538228
申请日：2003-12-12
申请人： Gustave Bergnes , Dashyant Dhanak , Steven Knight , Pu Lu , David Morgans , Kenneth Newlander
发明人： Gustave Bergnes , Dashyant Dhanak , Steven Knight , Pu Lu , David Morgans , Kenneth Newlander
IPC分类号： A61K31/554 , A61K31/55 , A61K31/553 , C07D403/02 , C07D413/02 , C07D417/02
CPC分类号： C07D403/06
摘要： Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of KSP are disclosed.
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公开(公告)号：US20060247289A1
公开(公告)日：2006-11-02
申请号：US11271147
申请日：2005-11-09
申请人： Xiangping Qian , Andrew McDonald , Han-Jie Zhou , Luke Ashcraft , Bing Yao , Hong Jiang , Jennifer Kuo Chen Huang , Jianchao Wang , David Morgans , Bradley Morgan , Gustave Bergnes , Dashyant Dhanak , Steven Knight , Nicholas Adams , Cynthia Parrish , Kevin Duffy , Duke Fitch , Rosanna Tedesco
发明人： Xiangping Qian , Andrew McDonald , Han-Jie Zhou , Luke Ashcraft , Bing Yao , Hong Jiang , Jennifer Kuo Chen Huang , Jianchao Wang , David Morgans , Bradley Morgan , Gustave Bergnes , Dashyant Dhanak , Steven Knight , Nicholas Adams , Cynthia Parrish , Kevin Duffy , Duke Fitch , Rosanna Tedesco
IPC分类号： A61K31/4184 , A61K31/4172 , C07D233/61
CPC分类号： C07D233/64 , C07C235/48 , C07C235/50 , C07C235/52 , C07C237/22 , C07C255/57 , C07C255/59 , C07C255/60 , C07C257/08 , C07C257/18 , C07C259/18 , C07C271/20 , C07C271/24 , C07C271/28 , C07C275/26 , C07C275/40 , C07C275/42 , C07C281/06 , C07C307/10 , C07C311/37 , C07C311/46 , C07C2601/02 , C07C2601/14 , C07D207/273 , C07D211/34 , C07D211/76 , C07D213/30 , C07D231/12 , C07D231/14 , C07D233/61 , C07D233/70 , C07D235/06 , C07D235/16 , C07D235/18 , C07D235/26 , C07D239/36 , C07D249/08 , C07D257/04 , C07D261/08 , C07D263/10 , C07D263/12 , C07D263/32 , C07D271/06 , C07D271/07 , C07D271/10 , C07D271/113 , C07D277/30 , C07D277/42 , C07D277/56 , C07D285/02 , C07D285/125 , C07D295/145 , C07D295/155 , C07D333/38 , C07D403/10 , C07D403/12 , C07D413/06 , C07D471/04 , C07D498/04 , C07F9/6506 , C07F9/6561
摘要： Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of one or more mitotic kinesins are disclosed.
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公开(公告)号：US20060004073A1
公开(公告)日：2006-01-05
申请号：US11172400
申请日：2005-06-29
IPC分类号： A61K31/4178
CPC分类号： C07D309/38
摘要： Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of KSP are disclosed.
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公开(公告)号：US20060094708A1
公开(公告)日：2006-05-04
申请号：US11121709
申请日：2005-05-03
申请人： Xiangping Qian , Andrew McDonald , Han-Jie Zhou , Luke Ashcraft , Bing Yao , Hong Jiang , Jennifer Chen Huang , Jianchao Wang , David Morgans , Bradley Morgan , Gustave Bergnes , Dashyant Dhanak , Steven Knight , Nicholas Adams , Cynthia Parrish
发明人： Xiangping Qian , Andrew McDonald , Han-Jie Zhou , Luke Ashcraft , Bing Yao , Hong Jiang , Jennifer Chen Huang , Jianchao Wang , David Morgans , Bradley Morgan , Gustave Bergnes , Dashyant Dhanak , Steven Knight , Nicholas Adams , Cynthia Parrish
IPC分类号： A61K31/55 , A61K31/4745 , A61K31/424 , A61K31/421 , A61K31/4196 , A61K31/4184 , C07D491/02 , C07D487/02
CPC分类号： C07D403/12 , C07C235/48 , C07C235/50 , C07C235/52 , C07C237/22 , C07C255/57 , C07C257/18 , C07C259/18 , C07C271/20 , C07C271/28 , C07C275/40 , C07C281/06 , C07C311/37 , C07C2601/14 , C07D207/273 , C07D211/76 , C07D213/30 , C07D231/12 , C07D233/62 , C07D235/18 , C07D235/26 , C07D261/08 , C07D263/10 , C07D271/06 , C07D277/56 , C07D285/02 , C07D295/155 , C07D333/38 , C07D403/10 , C07D471/04 , C07F9/6506 , C07F9/6561
摘要： Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of one or more mitotic kinesins are disclosed.
摘要翻译： 公开了通过调节一种或多种有丝分裂驱动蛋白的活性来治疗细胞增殖性疾病和病症的化合物。
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公开(公告)号：US20070197481A1
公开(公告)日：2007-08-23
申请号：US11124608
申请日：2005-05-06
申请人： Xiangping Qian , Andrew McDonald , Han-Jie Zhou , Luke Ashcraft , Bing Yao , Hong Jiang , Jennifer Kuo Chen Huang , Jianchao Wang , David Morgans , Bradley Morgan , Gustave Bergnes , Dashyant Dhanak , Steven Knight , Nicholas Adams , Cynthia Parrish , Kevin Duffy , Duke Fitch , Rosanna Tedesco
发明人： Xiangping Qian , Andrew McDonald , Han-Jie Zhou , Luke Ashcraft , Bing Yao , Hong Jiang , Jennifer Kuo Chen Huang , Jianchao Wang , David Morgans , Bradley Morgan , Gustave Bergnes , Dashyant Dhanak , Steven Knight , Nicholas Adams , Cynthia Parrish , Kevin Duffy , Duke Fitch , Rosanna Tedesco
IPC分类号： A61K31/66 , A61K31/538 , A61K31/4172 , A61K31/4745 , A61K31/426 , A61K31/421
CPC分类号： C07D403/12 , A61K31/4172 , A61K31/421 , A61K31/426 , A61K31/4745 , A61K31/538 , A61K31/66 , A61K45/06 , C07C235/48 , C07C235/50 , C07C237/22 , C07C255/44 , C07C255/57 , C07C255/60 , C07C271/28 , C07C2601/14 , C07D207/273 , C07D211/76 , C07D231/12 , C07D235/18 , C07D239/22 , C07D261/08 , C07D271/06 , C07D277/42 , C07D285/12 , C07D295/15 , C07D333/38 , C07D471/04 , C07D487/04 , C07D498/04 , C07D513/04 , A61K2300/00
摘要： Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of one or more mitotic kinesins are disclosed.
摘要翻译： 公开了通过调节一种或多种有丝分裂驱动蛋白的活性来治疗细胞增殖性疾病和病症的化合物。
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公开(公告)号：US20060019988A1
公开(公告)日：2006-01-26
申请号：US11188287
申请日：2005-07-21
申请人： Andrew McDonald , Pu-Ping Lu , Gustave Bergnes , David Morgans , Dashyant Dhanak , Steven Knight
发明人： Andrew McDonald , Pu-Ping Lu , Gustave Bergnes , David Morgans , Dashyant Dhanak , Steven Knight
IPC分类号： C07D217/22 , A61K31/47
CPC分类号： C07D401/06 , C07D217/24
摘要： Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of KSP are disclosed.
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