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1.发明申请公开(公告)号：US20250130230A1
公开(公告)日：2025-04-24
申请号：US18691615
申请日：2022-09-27
Applicant: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY , UNIVERSITY OF WASHINGTON
Inventor： Chao Wang , Liangcai Gu , Xiahui Chen , Shoukai Kang , MD Ashif Ikbal , Zhi Zhao
IPC: G01N33/569 , G01N33/543 , G01N33/553
Abstract: Provided herein are methods of detecting severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) in a sample. The methods include contacting the sample with a plurality of gold nanoparticles (AuNPs) and/or other plasmonic metal nanoparticles (MNPs) that are conjugated with at least two sets of antibodies, or antigen binding portions thereof, that binds to at least first and second epitopes of SARS-CoV-2 proteins, such as receptor-binding domain (RBDs) under conditions sufficient for the antibodies, or the antigen binding portions thereof, to bind to the first and second epitopes of the SARS-CoV-2 proteins in the sample to produce bound SARS-CoV-2 proteins. The methods also include detecting the SARS-CoV-2 proteins when aggregations of the bound SARS-CoV-2 proteins form with one another. Related compositions, reaction mixtures, devices, kits, and systems are also provided.
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公开(公告)号：US12117344B2
公开(公告)日：2024-10-15
申请号：US17743937
申请日：2022-05-13
Inventor： Yu Yao , Chao Wang , Chu Wang , Jing Bai , Ali Basiri , Xiahui Chen
CPC classification number: G01J4/04 , G02B5/3025
Abstract: A method of fabricating a polarization sensor is described. It includes a quarter-wave plate to convert circularly polarized light into linearly polarized light. The quarter-wave plate is realized as a metasurface. The sensor also includes a linear polarizer to analyze the light generated by the quarter wave plate, and a photodetector to receive the analyzed light. The sensor may be combined with other linear polarization sensors to form a sensor capable of complete measurement of the polarization state of incident light.
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公开(公告)号：US20240418570A1
公开(公告)日：2024-12-19
申请号：US18748614
申请日：2024-06-20
Inventor： Yu Yao , Chao Wang , Chu Wang , Jing Bai , Ali Basiri , Xiahui Chen
Abstract: A method of fabricating a polarization sensor is described. It includes a quarter-wave plate to convert circularly polarized light into linearly polarized light. The quarter-wave plate is realized as a metasurface. The sensor also includes a linear polarizer to analyze the light generated by the quarter wave plate, and a photodetector to receive the analyzed light. The sensor may be combined with other linear polarization sensors to form a sensor capable of complete measurement of the polarization state of incident light.
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公开(公告)号：US20240209496A1
公开(公告)日：2024-06-27
申请号：US18545658
申请日：2023-12-19
Inventor： Chao Wang , Pengkun Xia
IPC: C23C16/04 , B01L3/00 , C12Q1/6869 , C23C16/02 , C23C16/34 , G01N27/04 , G01N33/487
CPC classification number: C23C16/042 , B01L3/502761 , C12Q1/6869 , C23C16/0227 , C23C16/345 , G01N27/04 , G01N33/48721 , B01L2200/0647 , B01L2300/0645 , B01L2300/16
Abstract: Fabricating a nanopore sensor includes depositing a first and second oxide layers on first and second sides of a sapphire substrate. The second oxide layer is patterned to form an etch mask having a mask opening in the second oxide layer. A crystalline orientation dependent wet anisotropic etch is performed on the second side of the sapphire substrate using the etch mask to form a cavity having sloped side walls through the sapphire substrate to yield an exposed portion of the first oxide layer, each of the sloped side walls being a crystalline facet aligned with a respective crystalline plane of the sapphire substrate. A silicon nitride layer is deposited on the first oxide layer. The exposed portion of the first oxide layer in the cavity is removed, thereby defining a silicon nitride membrane in the cavity. An opening is formed through the silicon nitride membrane.
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公开(公告)号：US20210226583A1
公开(公告)日：2021-07-22
申请号：US17153769
申请日：2021-01-20
Applicant: Arizona Board of Regents on behalf of Arizona State University , Sandia National Laboratories
Inventor： Yu Yao , Chao Wang , Julius Yellowhair , Jing Bai , Jiawei Zuo
Abstract: Provided herein are systems and related methods of performing solar field and receiver inspections based on polarimetric-enhanced imaging.
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Patent Agency Ranking
公开(公告)号：US11843350B2
公开(公告)日：2023-12-12
申请号：US17153769
申请日：2021-01-20
Applicant: Arizona Board of Regents on behalf of Arizona State University , Sandia National Laboratories
Inventor： Yu Yao , Chao Wang , Julius Yellowhair , Jing Bai , Jiawei Zuo
IPC: H02S50/15 , B64C39/02 , G06T7/00 , B64U101/30
CPC classification number: H02S50/15 , B64C39/024 , G06T7/0004 , B64U2101/30 , G06T2207/10032 , G06T2207/10048
Abstract: Provided herein are systems and related methods of performing solar field and receiver inspections based on polarimetric-enhanced imaging.
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公开(公告)号：US11826946B2
公开(公告)日：2023-11-28
申请号：US17365024
申请日：2021-07-01
CPC classification number: B29C64/00 , B22F1/054 , B22F10/12 , B33Y10/00 , B33Y70/10 , H05K1/092 , B22F2301/255 , B22F2998/10 , B22F2999/00 , B22F2999/00 , B22F9/24 , B22F2202/11
Abstract: An additive manufacturing process for forming a metallic layer on the surface of the substrate includes fabricating a substrate from a polymerizable composition by a stereolithographic process, and contacting the reactive surface with an aqueous solution including a metal precursor. The metal precursor includes a metal, and the polymerizable composition includes a multiplicity of multifunctional components. Each multifunctional component includes a reactive moiety extending from a surface of the substrate to form a reactive surface. An interface between the reactive surface and the aqueous solution is selectively irradiated to form nanoparticles including the metal in a desired pattern. The nanoparticles are chemically coupled to the reactive surface by reactive moieties, thereby forming a metallic layer on the surface of the substrate.
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公开(公告)号：US11385104B2
公开(公告)日：2022-07-12
申请号：US16956988
申请日：2018-12-21
Inventor： Yu Yao , Chao Wang , Chu Wang , Jing Bai , Ali Basiri , Xiahui Chen
Abstract: A polarization sensor is described. It includes a quarter-wave plate to convert circularly polarized light into linearly polarized light. The quarter-wave plate is realized as a metasurface. The sensor also includes a linear polarizer to analyze the light generated by the quarter-wave plate, and a photodetector to receive the analyzed light. The sensor may be combined with other linear polarization sensors to form a sensor capable of complete measurement of the polarization state of incident light. An array of these sensors can be integrated directly onto image sensors to form a polarimetric imager.
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公开(公告)号：US20210190593A1
公开(公告)日：2021-06-24
申请号：US16956988
申请日：2018-12-21
Inventor： Yu Yao , Chao Wang , Chu Wang , Jing Bai , Ali Basiri , Xiahui Chen
Abstract: A polarization sensor is described. It includes a quarter-wave plate to convert circularly polarized light into linearly polarized light. The quarter-wave plate is realized as a metasurface. The sensor also includes a linear polarizer to analyze the light generated by the quarter-wave plate, and a photodetector to receive the analyzed light. The sensor may be combined with other linear polarization sensors to form a sensor capable of complete measurement of the polarization state of incident light. An array of these sensors can be integrated directly onto image sensors to form a polarimetric imager.
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公开(公告)号：US11891689B2
公开(公告)日：2024-02-06
申请号：US17908795
申请日：2021-03-03
Inventor： Chao Wang , Pengkun Xia
IPC: C23C16/04 , B01L3/00 , C12Q1/6869 , C23C16/02 , C23C16/34 , G01N27/04 , G01N33/487
CPC classification number: C23C16/042 , B01L3/502761 , C12Q1/6869 , C23C16/0227 , C23C16/345 , G01N27/04 , G01N33/48721 , B01L2200/0647 , B01L2300/0645 , B01L2300/16
Abstract: Fabricating a nanopore sensor includes depositing a first and second oxide layers on first and second sides of a sapphire substrate. The second oxide layer is patterned to form an etch mask having a mask opening in the second oxide layer. A crystalline orientation dependent wet anisotropic etch is performed on the second side of the sapphire substrate using the etch mask to form a cavity having sloped side walls through the sapphire substrate to yield an exposed portion of the first oxide layer, each of the sloped side walls being a crystalline facet aligned with a respective crystalline plane of the sapphire substrate. A silicon nitride layer is deposited on the first oxide layer. The exposed portion of the first oxide layer in the cavity is removed, thereby defining a silicon nitride membrane in the cavity. An opening is formed through the silicon nitride membrane.
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