Microfluidic chip and droplet separation method

    公开(公告)号:US11701659B2

    公开(公告)日:2023-07-18

    申请号:US17355869

    申请日:2021-06-23

    Inventor: Ding Ding Lin Deng

    CPC classification number: B01L3/502792 B01L2400/0478

    Abstract: The present disclosure provides a microfluidic chip and a droplet separation method, and belongs to the field of biological chip technology. The microfluidic chip includes a first liquid tank and a second liquid tank opposite to each other and a channel layer therebetween. The channel layer includes a plurality of microfluidic channels separated from each other, first ends of the microfluidic channels are communicated with the first liquid tank, and second ends are communicated with the second liquid tank. The first liquid tank contains sample solution to be detected, and the second liquid tank contains encapsulating liquid. The sample solution to be detected entering the first liquid tank may be separated into a plurality of sample droplets through the microfluidic channels, the separated sample droplets enter the second liquid tank, so that the encapsulating liquid is encapsulated on a surface of each of the plurality of sample droplets.

    POLYMER MICROSPHERE AND PREPARATION METHOD THEREOF

    公开(公告)号:US20240316222A1

    公开(公告)日:2024-09-26

    申请号:US18638130

    申请日:2024-04-17

    CPC classification number: A61K49/1854 A61K9/5089

    Abstract: The present application provides a polymer microsphere and a preparing method thereof. The polymer microsphere includes a core and a shell coating the core; the core includes at least two magnetic particles and a dispersion located between two neighboring magnetic particles; the shell includes a main shell body and a modifying layer, and the modifying layer is located on one side of the main shell body that is away from the magnetic particles; and a material of the dispersion, a material of the main shell body and a material of the modifying layer are the same. The magnetic particles in the polymer microsphere have a good dispersibility, and, when heated, the magnetic attraction force and the magnetic responsiveness of the polymer microsphere can nearly maintain unchanged.

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