Microfluidic chip and droplet separation method

    公开(公告)号:US11701659B2

    公开(公告)日:2023-07-18

    申请号:US17355869

    申请日:2021-06-23

    发明人: Ding Ding Lin Deng

    摘要: The present disclosure provides a microfluidic chip and a droplet separation method, and belongs to the field of biological chip technology. The microfluidic chip includes a first liquid tank and a second liquid tank opposite to each other and a channel layer therebetween. The channel layer includes a plurality of microfluidic channels separated from each other, first ends of the microfluidic channels are communicated with the first liquid tank, and second ends are communicated with the second liquid tank. The first liquid tank contains sample solution to be detected, and the second liquid tank contains encapsulating liquid. The sample solution to be detected entering the first liquid tank may be separated into a plurality of sample droplets through the microfluidic channels, the separated sample droplets enter the second liquid tank, so that the encapsulating liquid is encapsulated on a surface of each of the plurality of sample droplets.

    MICROFLUIDIC CHIP, DROPLET GENERATION DEVICE AND METHOD FOR CONTROLLING DROPLET GENERATION SIZE

    公开(公告)号:US20240278230A1

    公开(公告)日:2024-08-22

    申请号:US18044296

    申请日:2022-05-13

    发明人: Yunqing Mu Ding Ding

    IPC分类号: B01L3/02

    摘要: The disclosure provides a microfluidic chip, a droplet generation device and a method for controlling a droplet generation size. The microfluidic chip includes a substrate and a first flow channel, a second flow channel and a third flow channel distributed on the substrate, the first flow channel, the second flow channel and the third flow channel intersecting to form a confluence area, the first flow channel being configured for a flow of a dispersed phase fluid from it, the second flow channel being configured for a flow of a continuous phase fluid from it, the dispersed phase fluid and the continuous phase fluid forming droplets in the third flow channel. The dispersed phase fluid flows in the first flow channel along a first direction, an orthographic projection of the first flow channel on the substrate has a first width which is constant in a second direction.

    Active pixel sensor and flat panel detector

    公开(公告)号:US11933924B2

    公开(公告)日:2024-03-19

    申请号:US17488259

    申请日:2021-09-28

    摘要: The present disclosure provides an active pixel sensor and a flat panel detector. The active pixel sensor includes: a light sensing device configured to convert light sensed by the light sensing device into charges and supply the charges to a floating diffusion node; an amplification sub-circuit configured to amplify a signal according to a potential at the floating diffusion node and output the amplified signal through the output terminal; an adjustment sub-circuit configured to adjust, in response to a first control signal, a conversion gain from an amount of the light sensed by the light sensing device to the potential at the floating diffusion node; and a read sub-circuit configured to transmit a voltage of the input terminal of the read sub-circuit to the output terminal of the read sub-circuit according to a scan signal provided by the scan line.

    POLYMER MICROSPHERE AND PREPARATION METHOD THEREOF

    公开(公告)号:US20240316222A1

    公开(公告)日:2024-09-26

    申请号:US18638130

    申请日:2024-04-17

    发明人: Zhihong Wu Ding Ding

    IPC分类号: A61K49/18 A61K9/50

    CPC分类号: A61K49/1854 A61K9/5089

    摘要: The present application provides a polymer microsphere and a preparing method thereof. The polymer microsphere includes a core and a shell coating the core; the core includes at least two magnetic particles and a dispersion located between two neighboring magnetic particles; the shell includes a main shell body and a modifying layer, and the modifying layer is located on one side of the main shell body that is away from the magnetic particles; and a material of the dispersion, a material of the main shell body and a material of the modifying layer are the same. The magnetic particles in the polymer microsphere have a good dispersibility, and, when heated, the magnetic attraction force and the magnetic responsiveness of the polymer microsphere can nearly maintain unchanged.