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公开(公告)号：US10188608B2
公开(公告)日：2019-01-29
申请号：US15593871
申请日：2017-05-12
Applicant: Covidien LP
Inventor： Phillip Blaskovich , Rachit Ohri , Lan Pham
IPC: A61L15/28 , A61K9/16 , A61K31/714 , A61K31/445 , A61K33/24 , B01J13/12 , A61L27/20
Abstract: A process for forming microspheres is disclosed. The process includes contacting a solvent with a modified cellulose to form a solution; contacting the modified cellulose solution with at least one bioactive agent to form a discontinuous phase liquid; contacting the discontinuous phase liquid with a continuous phase liquid to form an emulsion; and contacting the emulsion with a third phase liquid to extract the solvent from the emulsion, thereby forming a plurality of modified cellulose microspheres.
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公开(公告)号：US09814844B2
公开(公告)日：2017-11-14
申请号：US14011414
申请日：2013-08-27
Applicant: COVIDIEN LP
Inventor： Rachit Ohri , Lan Pham , Phillip D. Blaskovich , Les Hull , Rupal Ayer , Stephen H. Wu , Clifford J. Herman , William H. Nau, Jr. , Francesca Rossetto , Allison Waller , Wenxing Huang , Paul DiCarlo , Mantao Xu , Xingyan Lu , Jiagui Li , Qinlin Gu , Harold M. Martins
CPC classification number: A61M5/329 , A61B17/3421 , A61B17/3478 , A61B18/1477 , A61B18/1487 , A61B2017/3447 , A61B2018/00577 , A61B2018/143 , A61B2218/002 , A61M25/00 , A61M25/0097 , A61M2025/0037 , A61M2202/0007
Abstract: A drug-delivery cannula assembly includes a cannula housing adapted for receiving at least one obturator shaft of an obturator assembly therethrough, one or more cannulae, and a supply line coupled to the cannula housing. The cannula housing is adapted for receiving one or more obturator shafts of an obturator assembly therethrough. The one or more cannulae define a longitudinal axis and a passageway aligned with the longitudinal axis. The one or more cannulae each include a proximal end coupled to the cannula housing. The cannula housing is configured to fluidly-couple the one or more cannulae to a source of a drug delivery supply for supplying drugs via the supply line to the one or more cannulae.
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公开(公告)号：US11065204B2
公开(公告)日：2021-07-20
申请号：US16540426
申请日：2019-08-14
Applicant: Covidien LP
Inventor： Phillip Blaskovich , Rachit Ohri , Lan Pham
IPC: A61K9/16 , A61K31/714 , A61K31/445 , A61K33/24 , B01J13/12 , A61L15/28 , A61L27/20
Abstract: A process for forming microspheres is disclosed. The process includes contacting a solvent with a modified cellulose to form a solution; contacting the modified cellulose solution with at least one bioactive agent to form a discontinuous phase liquid; contacting the discontinuous phase liquid with a continuous phase liquid to form an emulsion; and contacting the emulsion with a third phase liquid to extract the solvent from the emulsion, thereby forming a plurality of modified cellulose microspheres.
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Patent Agency Ranking
公开(公告)号：US20200000727A1
公开(公告)日：2020-01-02
申请号：US16540426
申请日：2019-08-14
Applicant: Covidien LP
Inventor： Phillip Blaskovich , Rachit Ohri , Lan Pham
IPC: A61K9/16 , A61K31/714 , A61K31/445 , A61K33/24 , B01J13/12 , A61L15/28 , A61L27/20
Abstract: A process for forming microspheres is disclosed. The process includes contacting a solvent with a modified cellulose to form a solution; contacting the modified cellulose solution with at least one bioactive agent to form a discontinuous phase liquid; contacting the discontinuous phase liquid with a continuous phase liquid to form an emulsion; and contacting the emulsion with a third phase liquid to extract the solvent from the emulsion, thereby forming a plurality of modified cellulose microspheres.
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公开(公告)号：US10426730B2
公开(公告)日：2019-10-01
申请号：US16225169
申请日：2018-12-19
Applicant: Covidien LP
Inventor： Phillip Blaskovich , Rachit Ohri , Lan Pham
IPC: A61K9/16 , A61K31/714 , A61K31/445 , A61K33/24 , B01J13/12 , A61L15/28 , A61L27/20
Abstract: A process for forming microspheres is disclosed. The process includes contacting a solvent with a modified cellulose to form a solution; contacting the modified cellulose solution with at least one bioactive agent to form a discontinuous phase liquid; contacting the discontinuous phase liquid with a continuous phase liquid to form an emulsion; and contacting the emulsion with a third phase liquid to extract the solvent from the emulsion, thereby forming a plurality of modified cellulose microspheres.
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公开(公告)号：US20170246113A1
公开(公告)日：2017-08-31
申请号：US15593871
申请日：2017-05-12
Applicant: Covidien LP
Inventor： Phillip Blaskovich , Rachit Ohri , Lan Pham
IPC: A61K9/16 , A61K31/445 , A61K31/714
CPC classification number: A61K9/1682 , A61K9/1652 , A61K9/1694 , A61K31/445 , A61K31/714 , A61K33/24 , A61L15/28 , A61L27/20 , B01J13/12 , B01J13/125
Abstract: A process for forming microspheres is disclosed. The process includes contacting a solvent with a modified cellulose to form a solution; contacting the modified cellulose solution with at least one bioactive agent to form a discontinuous phase liquid; contacting the discontinuous phase liquid with a continuous phase liquid to form an emulsion; and contacting the emulsion with a third phase liquid to extract the solvent from the emulsion, thereby forming a plurality of modified cellulose microspheres.
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公开(公告)号：US09526568B2
公开(公告)日：2016-12-27
申请号：US14011438
申请日：2013-08-27
Applicant: COVIDIEN LP
Inventor： Rachit Ohri , Lan Pham , Phillip D. Blaskovich , Les Hull , Rupal Ayer , Stephen H. Wu , Clifford J. Herman , William H. Nau, Jr. , Francesca Rossetto , Allison Waller , Wenxing Huang , Paul Dicarlo
CPC classification number: A61M37/00 , A61B10/0233 , A61B10/06 , A61B18/1477 , A61B18/18 , A61B18/1815 , A61B2018/00011 , A61B2018/00029 , A61B2018/00577 , A61B2018/00946 , A61B2018/143 , A61B2018/1475 , A61B2018/1869 , A61B2034/2065 , A61B2218/002 , A61M5/007 , A61M5/158 , A61M5/48 , A61M2037/0007 , A61M2205/0266 , A61M2205/055 , A61N1/0428 , A61N1/306 , A61N5/022 , A61N5/045
Abstract: A drug-delivery device includes a body configured for attachment to a handle of an ablation device, a shaft portion defining a passageway therein, and a delivery lumen to provide for drug delivery to tissue. The body includes a proximal portion, a distal portion, and a contoured portion disposed therebetween. The contoured portion is configured for engagement with a contoured portion of the handle of the ablation device. The shaft portion includes a proximal end and a distal end. The proximal end of the shaft engages with an opening defined in the distal end of the body. The passageway of the shaft portion is configured to receive the delivery lumen slideably moveably therein. The delivery lumen includes a proximal portion and a distal portion. The drug-delivery device also includes a knob member coupled to the proximal portion of the delivery lumen.
Abstract translation: 药物递送装置包括构造成附接到消融装置的手柄的主体，在其中限定通道的轴部分和用于向组织提供药物输送的输送腔。 主体包括近端部分，远侧部分和设置在其间的轮廓部分。 轮廓部分构造成与消融装置的手柄的轮廓部分接合。 轴部分包括近端和远端。 轴的近端与限定在主体的远端中的开口接合。 轴部分的通道被构造成在其中可移动地容纳可滑动的输送腔。 输送腔包括近端部分和远端部分。 药物递送装置还包括联接到输送腔的近端部分的旋钮构件。
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公开(公告)号：US20190117575A1
公开(公告)日：2019-04-25
申请号：US16225169
申请日：2018-12-19
Applicant: Covidien LP
Inventor： Phillip Blaskovich , Rachit Ohri , Lan Pham
IPC: A61K9/16 , A61L27/20 , A61L15/28 , B01J13/12 , A61K31/445 , A61K31/714 , A61K33/24
CPC classification number: A61K9/1682 , A61K9/1652 , A61K9/1694 , A61K31/445 , A61K31/714 , A61K33/24 , A61L15/28 , A61L27/20 , B01J13/12 , B01J13/125
Abstract: A process for forming microspheres is disclosed. The process includes contacting a solvent with a modified cellulose to form a solution; contacting the modified cellulose solution with at least one bioactive agent to form a discontinuous phase liquid; contacting the discontinuous phase liquid with a continuous phase liquid to form an emulsion; and contacting the emulsion with a third phase liquid to extract the solvent from the emulsion, thereby forming a plurality of modified cellulose microspheres.
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