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公开(公告)号：US09814844B2
公开(公告)日：2017-11-14
申请号：US14011414
申请日：2013-08-27
Applicant: COVIDIEN LP
Inventor： Rachit Ohri , Lan Pham , Phillip D. Blaskovich , Les Hull , Rupal Ayer , Stephen H. Wu , Clifford J. Herman , William H. Nau, Jr. , Francesca Rossetto , Allison Waller , Wenxing Huang , Paul DiCarlo , Mantao Xu , Xingyan Lu , Jiagui Li , Qinlin Gu , Harold M. Martins
CPC classification number: A61M5/329 , A61B17/3421 , A61B17/3478 , A61B18/1477 , A61B18/1487 , A61B2017/3447 , A61B2018/00577 , A61B2018/143 , A61B2218/002 , A61M25/00 , A61M25/0097 , A61M2025/0037 , A61M2202/0007
Abstract: A drug-delivery cannula assembly includes a cannula housing adapted for receiving at least one obturator shaft of an obturator assembly therethrough, one or more cannulae, and a supply line coupled to the cannula housing. The cannula housing is adapted for receiving one or more obturator shafts of an obturator assembly therethrough. The one or more cannulae define a longitudinal axis and a passageway aligned with the longitudinal axis. The one or more cannulae each include a proximal end coupled to the cannula housing. The cannula housing is configured to fluidly-couple the one or more cannulae to a source of a drug delivery supply for supplying drugs via the supply line to the one or more cannulae.
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公开(公告)号：US20150224133A1
公开(公告)日：2015-08-13
申请号：US14694112
申请日：2015-04-23
Applicant: Covidien LP
Inventor： Rachit Ohri , Phillip D. Blaskovich
IPC: A61K31/717 , A61K31/445 , A61K49/00 , A61K33/24 , A61K31/295 , A61K47/22 , A61K31/714
CPC classification number: A61K31/717 , A61K31/282 , A61K31/295 , A61K31/445 , A61K31/714 , A61K33/24 , A61K49/048 , A61L24/06 , A61L2430/36 , C08L1/04
Abstract: A method for forming an embolism within a blood vessel is disclosed. The method includes including: implanting an oxidized cellulose embolization solution into a lumen of a blood vessel to form an embolism within the lumen. The oxidized cellulose is present in an amount from about 10% by weight to 20% by weight of the oxidized cellulose embolization solution. The method also includes adjusting recanalization time of the embolism, which may be adjusted by tailoring a degradation rate of the oxidized cellulose.
Abstract translation: 公开了一种在血管内形成栓塞的方法。 该方法包括：将氧化的纤维素栓塞溶液植入血管的内腔，以在内腔内形成栓塞。 氧化纤维素以氧化纤维素栓塞溶液的约10重量％至20重量％的量存在。 该方法还包括调节栓塞的再通时间，其可以通过调节氧化纤维素的降解速率来调节。
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公开(公告)号：US10982012B2
公开(公告)日：2021-04-20
申请号：US15353997
申请日：2016-11-17
Applicant: Covidien LP
Inventor： Valentino J. Tramontano , Joshua Kennedy , Sajida Farooqi , Phillip D. Blaskovich , Rachit Ohri , Daniel S. Costa
IPC: C08B16/00 , C08K3/16 , C08K5/20 , C08K5/3415 , C08J3/09 , C08B15/02 , C08J3/12 , C08L1/04 , A61K9/16
Abstract: A process for dissolving modified cellulose is disclosed. The process includes contacting modified cellulose with a solvent in a mixture to form swelled modified cellulose and then contacting the mixture with a salt to dissolve the swelled modified cellulose.
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公开(公告)号：US20140228559A1
公开(公告)日：2014-08-14
申请号：US14129187
申请日：2012-06-28
Applicant: COVIDIEN LP
Inventor： Valentino J. Tramontano , Joshua Kennedy , Sajida Farooqi , Phillip D. Blaskovich , Rachit Ohri , Daniel S. Costa
IPC: C08B15/02
CPC classification number: C08B16/00 , A61K9/1652 , C08B15/02 , C08J3/091 , C08J3/096 , C08J3/12 , C08J2301/02 , C08J2301/04 , C08K3/16 , C08K5/20 , C08K5/3415 , C08L1/04
Abstract: A process for dissolving modified cellulose is disclosed. The process includes contacting modified cellulose with a solvent in a mixture to form swelled modified cellulose and then contacting the mixture with a salt to dissolve the swelled modified cellulose.
Abstract translation: 公开了一种溶解改性纤维素的方法。 该方法包括使改性纤维素与溶剂在混合物中接触以形成溶胀的改性纤维素，然后使该混合物与盐接触以溶解溶胀的改性纤维素。
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公开(公告)号：US10561744B2
公开(公告)日：2020-02-18
申请号：US15899505
申请日：2018-02-20
Applicant: Covidien LP
Inventor： Rachit Ohri , Phillip D. Blaskovich
IPC: A61K49/00 , A61K9/50 , A61L31/18 , A61K49/22 , A61K49/04 , A61K49/18 , A61K51/12 , B82Y5/00 , B82Y30/00 , A61K31/282 , A61K31/445 , A61K31/714 , A61L31/04
Abstract: A microsphere and method for forming the same are disclosed. The microsphere includes modified cellulose and at least one of a visualization agent, a magnetic material, or a radioactive material.
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Patent Agency Ranking
公开(公告)号：US20190350965A1
公开(公告)日：2019-11-21
申请号：US16527740
申请日：2019-07-31
Applicant: Covidien LP
Inventor： Rachit Ohri , Phillip D. Blaskovich , Min-Shyan Sheu , Petra Brockfeld
IPC: A61K31/717 , A61K33/20 , A61L26/00 , A61K31/714 , A61K49/04 , A61K31/295 , A61K33/24 , A61K31/445
Abstract: A method of treatment includes agitating a thixotropic oxidized cellulose solution; administering the agitated thixotropic oxidized cellulose solution to a target tissue site; and allowing the agitated thixotropic oxidized cellulose solution to gel at the target tissue site.
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公开(公告)号：US08932618B2
公开(公告)日：2015-01-13
申请号：US13939720
申请日：2013-07-11
Applicant: Covidien LP
Inventor： Phillip D. Blaskovich , Rachit Ohri , Steven L. Bennett
CPC classification number: A61K9/0004 , A61K9/0024
Abstract: The present disclosure relates to a drug delivery device including a biodegradable housing and a hydrogel within the biodegradable housing. The housing, the hydrogel, or both, may include a bioactive agent. Also disclosed is a method of drug delivery including the steps of forming the biodegradable housing, in embodiments a hydrogel, suspending a bioactive agent in the hydrogel, and introducing a second hydrogel and/or precursors of a second hydrogel into the biodegradable housing.
Abstract translation: 本公开涉及一种药物递送装置，其包括可生物降解的壳体内的可生物降解的壳体和水凝胶。 壳体，水凝胶或两者可以包括生物活性剂。 还公开了药物递送的方法，包括形成可生物降解的壳体的步骤，在实施方案中为水凝胶，将生物活性剂悬浮在水凝胶中，以及将第二水凝胶和/或第二水凝胶的前体引入可生物降解的壳体中。
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公开(公告)号：US11872244B2
公开(公告)日：2024-01-16
申请号：US16527740
申请日：2019-07-31
Applicant: Covidien LP
Inventor： Rachit Ohri , Phillip D. Blaskovich , Min-Shyan Sheu , Petra Brockfeld
IPC: A61K31/717 , A61K31/445 , A61K31/714 , A61K33/24 , A61K31/295 , A61K49/04 , A61L26/00 , A61K33/20 , A61K33/243
CPC classification number: A61K31/717 , A61K31/295 , A61K31/445 , A61K31/714 , A61K33/20 , A61K33/24 , A61K33/243 , A61K49/048 , A61L26/0023 , A61L26/0061 , A61L26/0066 , A61L2400/06 , A61L26/0023 , C08L1/04
Abstract: A method of treatment includes agitating a thixotropic oxidized cellulose solution; administering the agitated thixotropic oxidized cellulose solution to a target tissue site; and allowing the agitated thixotropic oxidized cellulose solution to gel at the target tissue site.
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公开(公告)号：US10413566B2
公开(公告)日：2019-09-17
申请号：US15235261
申请日：2016-08-12
Applicant: Covidien LP
Inventor： Rachit Ohri , Phillip D. Blaskovich
IPC: A61K31/717 , A61K31/445 , A61K31/714 , A61K33/24 , A61K31/295 , A61K49/04 , A61L26/00
Abstract: A method of treatment includes agitating a thixotropic oxidized cellulose solution; administering the agitated thixotropic oxidized cellulose solution to a target tissue site; and allowing the agitated thixotropic oxidized cellulose solution to gel at the target tissue site.
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公开(公告)号：US09919063B2
公开(公告)日：2018-03-20
申请号：US14424464
申请日：2013-09-17
Applicant: Covidien LP
Inventor： Rachit Ohri , Phillip D. Blaskovich , Olga Cherniavsky
IPC: A61K51/00 , A61M36/14 , A01N43/04 , A61K49/00 , A61K49/22 , A61K49/04 , A61K49/18 , A61K51/12 , A61K9/50 , A61K31/282 , A61K31/445 , A61K31/714 , A61L31/04 , A61L31/18 , B82Y5/00 , B82Y30/00
CPC classification number: A61K49/00 , A61K9/5031 , A61K9/5042 , A61K9/5073 , A61K9/5084 , A61K31/282 , A61K31/445 , A61K31/714 , A61K49/0017 , A61K49/0091 , A61K49/04 , A61K49/1818 , A61K49/225 , A61K51/1251 , A61L31/042 , A61L31/18 , B82Y5/00 , B82Y30/00 , C08L1/00
Abstract: A microsphere and method for forming the same are disclosed. The microsphere includes modified cellulose and at least one of a visualization agent, a magnetic material, or a radioactive material.
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