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公开(公告)号：US11872244B2
公开(公告)日：2024-01-16
申请号：US16527740
申请日：2019-07-31
申请人： Covidien LP
IPC分类号： A61K31/717 , A61K31/445 , A61K31/714 , A61K33/24 , A61K31/295 , A61K49/04 , A61L26/00 , A61K33/20 , A61K33/243
CPC分类号： A61K31/717 , A61K31/295 , A61K31/445 , A61K31/714 , A61K33/20 , A61K33/24 , A61K33/243 , A61K49/048 , A61L26/0023 , A61L26/0061 , A61L26/0066 , A61L2400/06 , A61L26/0023 , C08L1/04
摘要： A method of treatment includes agitating a thixotropic oxidized cellulose solution; administering the agitated thixotropic oxidized cellulose solution to a target tissue site; and allowing the agitated thixotropic oxidized cellulose solution to gel at the target tissue site.
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公开(公告)号：US10584184B2
公开(公告)日：2020-03-10
申请号：US16022772
申请日：2018-06-29
申请人： Covidien LP
摘要： A process for dissolving modified cellulose includes contacting modified cellulose with a solvent in a mixture to form swelled modified cellulose and then contacting the mixture with a salt to dissolve the swelled modified cellulose. The dissolved modified cellulose is used to form at least one of a predictably degrading coating, film, or a fiber.
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公开(公告)号：US10413566B2
公开(公告)日：2019-09-17
申请号：US15235261
申请日：2016-08-12
申请人： Covidien LP
发明人： Rachit Ohri , Phillip D. Blaskovich
IPC分类号： A61K31/717 , A61K31/445 , A61K31/714 , A61K33/24 , A61K31/295 , A61K49/04 , A61L26/00
摘要： A method of treatment includes agitating a thixotropic oxidized cellulose solution; administering the agitated thixotropic oxidized cellulose solution to a target tissue site; and allowing the agitated thixotropic oxidized cellulose solution to gel at the target tissue site.
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公开(公告)号：US09919063B2
公开(公告)日：2018-03-20
申请号：US14424464
申请日：2013-09-17
申请人： Covidien LP
IPC分类号： A61K51/00 , A61M36/14 , A01N43/04 , A61K49/00 , A61K49/22 , A61K49/04 , A61K49/18 , A61K51/12 , A61K9/50 , A61K31/282 , A61K31/445 , A61K31/714 , A61L31/04 , A61L31/18 , B82Y5/00 , B82Y30/00
CPC分类号： A61K49/00 , A61K9/5031 , A61K9/5042 , A61K9/5073 , A61K9/5084 , A61K31/282 , A61K31/445 , A61K31/714 , A61K49/0017 , A61K49/0091 , A61K49/04 , A61K49/1818 , A61K49/225 , A61K51/1251 , A61L31/042 , A61L31/18 , B82Y5/00 , B82Y30/00 , C08L1/00
摘要： A microsphere and method for forming the same are disclosed. The microsphere includes modified cellulose and at least one of a visualization agent, a magnetic material, or a radioactive material.
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公开(公告)号：US09687450B2
公开(公告)日：2017-06-27
申请号：US15054479
申请日：2016-02-26
申请人： Covidien LP
IPC分类号： A61K9/16 , A61K31/714 , A61K31/445 , A61K33/24 , B01J13/12 , A61L15/28 , A61L27/20
CPC分类号： A61K9/1682 , A61K9/1652 , A61K9/1694 , A61K31/445 , A61K31/714 , A61K33/24 , A61L15/28 , A61L27/20 , B01J13/12 , B01J13/125
摘要： A process for forming microspheres is disclosed. The process includes contacting a solvent with a modified cellulose to form a solution; contacting the modified cellulose solution with at least one bioactive agent to form a discontinuous phase liquid; contacting the discontinuous phase liquid with a continuous phase liquid to form an emulsion; and contacting the emulsion with a third phase liquid to extract the solvent from the emulsion, thereby forming a plurality of modified cellulose microspheres.
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公开(公告)号：US20170066846A1
公开(公告)日：2017-03-09
申请号：US15353997
申请日：2016-11-17
申请人： Covidien LP
发明人： Valentino J. Tramontano , Joshua Kennedy , Sajida Farooqi , Phillip D. Blaskovich , Rachit Ohri , Daniel S. Costa
CPC分类号： C08B16/00 , A61K9/1652 , C08B15/02 , C08J3/091 , C08J3/096 , C08J3/12 , C08J2301/02 , C08J2301/04 , C08K3/16 , C08K5/20 , C08K5/3415 , C08L1/04
摘要： A process for dissolving modified cellulose is disclosed. The process includes contacting modified cellulose with a solvent in a mixture to form swelled modified cellulose and then contacting the mixture with a salt to dissolve the swelled modified cellulose.
摘要翻译： 公开了一种溶解改性纤维素的方法。 该方法包括使改性纤维素与溶剂在混合物中接触以形成溶胀的改性纤维素，然后使该混合物与盐接触以溶解溶胀的改性纤维素。
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7.发明申请Crosslinked Polymers with the Crosslinker as Therapeutic for Sustained Release 有权交联聚合物与交联剂作为持续释放的治疗剂公开(公告)号：US20130225857A1
公开(公告)日：2013-08-29
申请号：US13862500
申请日：2013-04-15
IPC分类号： C07C231/02 , C08G65/00
CPC分类号： C07C231/02 , A61K47/30 , A61K47/60 , A61K47/6903 , C07D207/46 , C08G65/00 , Y10T428/31551
摘要： Crosslinked polymers, methods for their preparation and use, are described in which the crosslinked polymers are formed from at least two polymer precursors, one of which is designed, upon degradation of the crosslinked polymer, to release the second polymer precursor in its original, unmodified chemical form.
摘要翻译： 描述了交联聚合物，其制备和使用方法，其中交联聚合物由至少两种聚合物前体形成，其中一种聚合物前体在交联聚合物降解时被设计为以其原始的未改性的方式释放第二聚合物前体 化学形式。
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公开(公告)号：US11873350B2
公开(公告)日：2024-01-16
申请号：US17233694
申请日：2021-04-19
申请人： Covidien LP
发明人： Valentino J. Tramontano , Joshua Kennedy , Philip D. Blaskovich , Rachit Ohri , Daniel S. Costa , Sajida Farooqi
IPC分类号： C08B16/00 , C08K3/16 , C08K5/20 , C08K5/3415 , C08J3/09 , C08B15/02 , C08J3/12 , C08L1/04 , A61K9/16
CPC分类号： C08B16/00 , C08B15/02 , C08J3/091 , C08J3/096 , C08J3/12 , C08K3/16 , C08K5/20 , C08K5/3415 , C08L1/04 , A61K9/1652 , C08J2301/02 , C08J2301/04 , C08L1/04 , C08K3/16 , C08K5/3415 , C08L1/04 , C08K3/16 , C08K5/20 , C08K3/06 , C08L1/04 , C08K5/3415 , C08L1/04 , C08K5/20 , C08L1/04
摘要： A process for dissolving modified cellulose is disclosed. The process includes contacting modified cellulose with a solvent in a mixture to form swelled modified cellulose and then contacting the mixture with a salt to dissolve the swelled modified cellulose.
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9.发明授权公开(公告)号：US11053323B2
公开(公告)日：2021-07-06
申请号：US15344633
申请日：2016-11-07
申请人： Covidien LP
发明人： Phillip Blaskovich , Valentino Tramontano , Rachit Ohri , Joshua Kennedy , Christopher M. Henry
摘要： A process for dissolving modified cellulose includes contacting modified cellulose solution with at least one multivalent cation to form a plurality of modified cellulose particles.
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公开(公告)号：US10561744B2
公开(公告)日：2020-02-18
申请号：US15899505
申请日：2018-02-20
申请人： Covidien LP
发明人： Rachit Ohri , Phillip D. Blaskovich
IPC分类号： A61K49/00 , A61K9/50 , A61L31/18 , A61K49/22 , A61K49/04 , A61K49/18 , A61K51/12 , B82Y5/00 , B82Y30/00 , A61K31/282 , A61K31/445 , A61K31/714 , A61L31/04
摘要： A microsphere and method for forming the same are disclosed. The microsphere includes modified cellulose and at least one of a visualization agent, a magnetic material, or a radioactive material.
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