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    Prosthetic heart valve
    1.
    发明授权
    Prosthetic heart valve 有权

    公开(公告)号：US12029646B2

    公开(公告)日：2024-07-09

    申请号：US18216391

    申请日：2023-06-29

    Applicant: CARDIOVALVE LTD.

    Inventor： Ilia Hariton ,  Meni Iamberger ,  Boaz Harari ,  Aviram Baum

    IPC: A61F2/24

    CPC classification number: A61F2/2418 ,  A61F2/24 ,  A61F2/2427 ,  A61F2/2436 ,  A61F2210/0014 ,  A61F2220/0008 ,  A61F2220/0075 ,  A61F2250/0003 ,  A61F2250/0039

    Abstract: A prosthetic valve is provided that includes a tubular valve body and a plurality of prosthetic leaflets disposed within a lumen of the valve body. The valve body includes struts, has an upstream end and a downstream end, and defines a lumen. The valve body is shaped so as to define a circumferential row of four-sided closed cells. Each of the four-sided closed cells is defined by some of the struts, which are shaped so as to collectively define the following four sides: a left upstream side, a right upstream side, a left downstream side, and a right downstream side. Each of the four sides of each of the four-sided closed cells is double-strutted. Other embodiments are also described.

    PROSTHETIC HEART VALVE
    3.
    发明公开
    PROSTHETIC HEART VALVE 审中-公开

    公开(公告)号：US20230390053A1

    公开(公告)日：2023-12-07

    申请号：US18234745

    申请日：2023-08-16

    Applicant: CARDIOVALVE LTD.

    Inventor： Ilia Hariton ,  Meni Iamberger ,  Boaz Harari ,  Aviram Baum

    IPC: A61F2/24

    CPC classification number: A61F2/2418 ,  A61F2/24 ,  A61F2220/0075 ,  A61F2/2427 ,  A61F2250/0039 ,  A61F2210/0014 ,  A61F2220/0008 ,  A61F2/2436 ,  A61F2250/0003

    Abstract: A prosthetic valve is provided that includes a tubular valve body and a plurality of prosthetic leaflets disposed within a lumen of the valve body. The valve body includes struts, has an upstream end and a downstream end, and defines a lumen. The valve body is shaped so as to define a circumferential row of four-sided closed cells. Each of the four-sided closed cells is defined by some of the struts, which are shaped so as to collectively define the following four sides: a left upstream side, a right upstream side, a left downstream side, and a right downstream side. Exactly two of the four sides of each of the four-sided closed cells are double-strutted. Other embodiments are also described.

    Techniques for deployment of a prosthetic valve
    4.
    发明授权
    Techniques for deployment of a prosthetic valve 有权

    公开(公告)号：US11801135B2

    公开(公告)日：2023-10-31

    申请号：US17141853

    申请日：2021-01-05

    Applicant: CARDIOVALVE LTD.

    Inventor： Ilia Hariton ,  Boaz Harari ,  Maxim Karalnik ,  Meni Iamberger

    IPC: A61F2/24 ,  A61F2/95 ,  A61F2/915

    CPC classification number: A61F2/2436 ,  A61F2/243 ,  A61F2/2409 ,  A61F2/2418 ,  A61F2/9517 ,  A61F2002/91575 ,  A61F2220/0016 ,  A61F2220/0025

    Abstract: A method includes percutaneously advancing an implant to a native heart valve of a subject, the implant being housed in a compressed state within a delivery tool. Next, the method includes unhousing a longitudinally-intermediate portion of the implant, the longitudinally-intermediate portion being longitudinally between a longitudinally-proximal portion of the implant and a longitudinally distal portion of the implant. Subsequently, the longitudinally-proximal portion of the implant is unhoused. Subsequently, the longitudinally-distal portion of the implant is unhoused. By unhousing flanges of the implant, the flanges automatically expand. Upon the flanges expanding, a proximal end of each flange extends radially outward from a central longitudinal axis of the implant and longitudinally in a proximal direction. Other applications are also described.

    Techniques for use with prosthetic valve leaflets
    6.
    发明授权
    Techniques for use with prosthetic valve leaflets 有权

    公开(公告)号：US11648122B2

    公开(公告)日：2023-05-16

    申请号：US17353063

    申请日：2021-06-21

    Applicant: CARDIOVALVE LTD.

    Inventor： Boaz Harari ,  Ilia Hariton

    IPC: A61F2/24 ,  G01N3/04 ,  G01L1/24 ,  G01B11/02 ,  H04N7/18 ,  A61F2/76 ,  G01B11/14

    CPC classification number: A61F2/2472 ,  G01L1/24 ,  G01N3/04 ,  A61F2002/7635 ,  G01B11/02 ,  G01B11/14 ,  H04N7/18

    Abstract: Apparatus (20) for testing a prosthetic leaflet (10) includes a bar (22); a light source (24); a detector (26); an actuator (40); a gauge (28); a display (82); and circuitry (84). The leaflet is draped over the bar. The light source emits a beam of light (32). The detector detects the beam, and generates a detection-signal indicative of detection of the beam. Actuation of the actuator moves the bar with respect to the beam. The gauge measures an elevation of the bar above the beam, the elevation changing with the moving of the bar by the actuator. The circuitry is configured: (i) to receive the measured elevation from the gauge, (ii) to receive the detection-signal from the detector, and (iii) in response to the detection-signal, to drive the display to display the elevation that was measured when the detection-signal was received by the circuitry.

    Prosthetic valve and delivery tool therefor
    7.
    发明授权
    Prosthetic valve and delivery tool therefor 有权

    公开(公告)号：US11382746B2

    公开(公告)日：2022-07-12

    申请号：US16768909

    申请日：2018-12-12

    Applicant: CARDIOVALVE LTD.

    Inventor： Ilia Hariton ,  Boaz Harari

    IPC: A61F2/24

    Abstract: Embodiments of the present disclosure include apparatus for use at a native valve of a heart of a subject. A delivery tool has a shaft, a capsule disposed at a distal portion of the tool, and a balloon that is disposed within the capsule and coupled to the shaft. A tubular frame of a prosthetic valve is compressed around the balloon, such that shape-memory flanges of the prosthetic valve, and a shape-memory upstream support portion of the prosthetic valve, are each constrained within a respective capsule-portion of the capsule. The capsule is openable by moving the capsule-portions apart, such that the flanges and the upstream support portion automatically deflect radially outward, while the tubular frame remains compressed around the balloon, and inflation of the balloon plastically expands the tubular frame radially. Other embodiments are also described.

    Prosthetic valve with atrial tissue anchors having variable flexibility and ventricular tissue anchors having constant flexibility
    8.
    发明授权
    Prosthetic valve with atrial tissue anchors having variable flexibility and ventricular tissue anchors having constant flexibility 有权

    公开(公告)号：US11304806B2

    公开(公告)日：2022-04-19

    申请号：US16136082

    申请日：2018-09-19

    Applicant: CARDIOVALVE LTD.

    Inventor： Ilia Hariton ,  Meni Iamberger ,  Aviram Baum ,  Boaz Harari

    IPC: A61F2/24

    Abstract: Prosthetic valves and methods of implanting prosthetic valves may be provided, including an expandable prosthetic valve for implantation within a native heart valve. The prosthetic valve may include an annular valve body and atrial anchoring arms configured to extend radially outward from the annular valve body. Each atrial anchoring arm may have a proximal arm end and a distal arm end. The flexibility of at least one atrial anchoring arm may vary substantially from the proximal arm end thereof to the distal arm end thereof. The prosthetic valve may also include a plurality of ventricular anchoring legs configured to extend radially outward from the annular valve body. Each ventricular anchoring leg may have a proximal leg end and a distal leg end. Each ventricular anchoring leg may have a substantially constant flexibility from the proximal leg end to the distal leg end.

    Prosthetic valve with connecting struts of variable size and tissue anchoring legs of variable size that extend from junctions
    9.
    发明授权
    Prosthetic valve with connecting struts of variable size and tissue anchoring legs of variable size that extend from junctions 有权

    公开(公告)号：US11304804B2

    公开(公告)日：2022-04-19

    申请号：US16135599

    申请日：2018-09-19

    Applicant: CARDIOVALVE LTD.

    Inventor： Ilia Hariton ,  Meni Iamberger ,  Aviram Baum ,  Boaz Harari

    IPC: A61F2/24

    Abstract: An expandable prosthetic valve for implantation within a native mitral valve may be provided. The prosthetic valve may include an expandable valve body having an atrial end, a ventricular end opposite the atrial end, and an intermediate portion extending between the atrial end and the ventricular end. The valve body may include a plurality of struts intersecting at junctions. The prosthetic valve may also include a plurality of tissue anchoring legs extending from junctions within the intermediate portion of the valve body. At least one of the tissue anchoring legs may have a cross-sectional area which is larger by at least 20% than a cross-sectional area of a strut extending between the at least one tissue anchoring leg and an adjacent tissue anchoring leg.

    Prosthetic valve with protective sleeve around an outlet rim
    10.
    发明授权
    Prosthetic valve with protective sleeve around an outlet rim 有权

    公开(公告)号：US10905548B2

    公开(公告)日：2021-02-02

    申请号：US16135770

    申请日：2018-09-19

    Applicant: CARDIOVALVE LTD.

    Inventor： Ilia Hariton ,  Meni Iamberger ,  Aviram Baum ,  Boaz Harari

    IPC: A61F2/24

    Abstract: An expandable prosthetic valve for implantation within a native heart valve may be provided. The prosthetic valve may include an expandable annular valve body. The valve body may include an atrial inlet opening and a ventricular outlet opening. The valve body may additionally include a plurality of tissue anchors extending from the valve body. The prosthetic valve may additionally include a flexible annular protective sleeve positioned about the rim of the valve body outlet opening and affixed to the outlet opening.

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