摘要:
The present invention is directed to methods of inhibiting a tauopathy in a patient by administration of a compound of formula I: Novel aminothienopyridazine compounds are also described.
摘要:
Amido compounds are disclosed that have a formula represented by the following: and wherein Cy1, Cy2, n1, n2, R1a, R1b, R2, R3, R4, R5, and R6 are as described herein. The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, inflammatory conditions, autoimmune disorders, cancer, and graft-versus-host disease.
摘要:
Amido compounds are disclosed that have a formula represented by the following: and wherein n1, n2, R1a, R1b, R2, R3, R4, R5, and R6 are as described herein. The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, inflammatory conditions, autoimmune disorders, cancer, and graft-versus-host disease.
摘要:
Heterocyclic compounds, and pharmaceutical compositions thereof, are disclosed as RORγt modulators that have a formula represented by the following: and wherein n1, n2, R1, R2, R3, and R4 are as described herein. These compounds may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, inflammatory conditions, autoimmune disorders, cancer, and graft-versus-host disease.
摘要:
Amido compounds are disclosed that have a formula represented by the following: and wherein Cy1, Cy2, n1, n2, R1a, R1b, R2, R3, R4, R5, and R6 are as described herein. The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, inflammatory conditions, autoimmune disorders, cancer, and graft-versus-host disease.
摘要:
Amido compounds are disclosed that have a formula represented by the following: and wherein n1, n2, R1a, R1b, R2, R3, R4, R5, and R6 are as described herein. The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, inflammatory conditions, autoimmune disorders, cancer, and graft-versus-host disease.
摘要:
Heterocyclic compounds, and pharmaceutical compositions thereof, are disclosed as RORγt modulators that have a formula represented by the following: and wherein n1, n2, R1, R2, R3, and R4 are as described herein. These compounds may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, inflammatory conditions, autoimmune disorders, cancer, and graft-versus-host disease.
摘要:
This invention relates to a method of speed control selection for an electronically commutated motor comprising the following steps: (a) a motor controller receives an input signal T from a speed control selection circuit; (b) the motor controller retrieves a corresponding value for a motor running speed S from a comparison list correlating the input signal with the motor running speed, which list has been stored in the motor controller in advance, by searching the comparison list for the input signal T; and (c) the motor controller controlling a motor M to run at the motor running speed S, achieving the purpose of the speed selection. This method allows for from 2 to 256 speed choices with a single signal wire only. Such a circuit structure has the advantages of high integration, simple wiring, low cost, good performances, low failure rate, higher number of optional speeds, and simpler and more practical control.
摘要:
The invention teaches a brushless DC motor, comprising a brushless DC motor unit and a controller unit, wherein the brushless DC motor unit comprises a stator assembly, a permanent magnet rotor assembly magnetically coupled with the stator assembly, an enclosure supporting the installation of stator assembly and the permanent magnet rotator assembly, an end shield installed at the end of the enclosure, the rotating shaft of the permanent magnet rotor assembly projecting out of the end shield; the controller unit comprises an integrated power module, a microprocessor unit, a rotor position sensing circuit, a power source circuit, an I/O interface circuit, a current-sensing circuit, and a controller box; and the controller unit is electrically connected to the brushless DC motor unit. The brushless DC motor of the invention has an ideal control circuit with a plurality of control units serving to control the motor operation characteristics stored in the microprocessor unit so that the brushless DC motor is broadly universal and can be operated under a plurality of control modes.