摘要:
A method of treating an occluded blood vessel includes sensing the impedance at a plurality of locations around the circumference of the blood vessel at least two different frequencies to identify vascular occlusive material, and distinguish vascular occlusive material from the vessel wall.
摘要:
A system for radio frequency (RF) wire guidance during RF occlusion canalization including a RF wire configured to travel through a blood vessel, an impedance measure unit configured to measure an electrical impedance between the RF wire and a reference electrode, a RF power source, an activation controller configured to connect the RF power source to the RF wire when the impedance measure unit indicates that the RF wire is contacting an occlusion material, a RF wire steering system; and a controller configured to activate the steering system to maintain the RF wire within the occlusion material based on impedance measured by the impedance measure unit.
摘要:
A differential capable of automatically restricting a differential ratio and increasing torque comprises a container. A differential housing is provided in the container. The differential housing is internally provided with a planetary gear, a planetary shaft, a left half axle gear, and a right half axle gear. The planetary gear is provided on the planetary shaft, and the planetary gear engages with the left half axle gear and the right half axle gear, respectively. The differential housing comprises a left housing and a right housing engaging with each other. A ring gear is provided at the outer circumference of an end of the left housing engaging with the right housing, and a bevel ring gear is provided at the outer circumference of an end of the right housing engaging with the left housing.
摘要:
The present invention relates to novel analogs of glucagon like peptide and compositions that are useful for up-regulating insulin expression in mammals and for treating diabetes. In particular, these peptide derivatives have a peptide mimic linker and provides long duration of action for the treatment of diabetes and other insulinotropic peptide related diseases, gastrointestinal function and activities associated with glucagon levels.
摘要:
An electrode catheter (14) and a method for assessing electrode-tissue contact and coupling are disclosed. An exemplary electrode catheter (14) comprises an electrode (20) adapted to apply electrical energy. A measurement circuit (42) is adapted to measure impedance between the electrode (20) and ground as the electrode approaches a target tissue (24). A processor (50) determines a contact and coupling condition for the target tissue (24) based at least in part on reactance of the impedance measured by the measurement circuit (42). In another exemplary embodiment, the electrode catheter (14) determines the contact and coupling condition based at least in part on a phase angle of the impedance.
摘要:
An electrode catheter and a method for assessing electrode-tissue contact and coupling are disclosed. An exemplary electrode catheter comprises an electrode adapted to apply electrical energy. A measurement circuit is adapted to measure impedance between the electrode and ground as the electrode approaches a target tissue. A processor determines a contact and coupling condition for the target tissue based at least in part on reactance of the impedance measured by the measurement circuit. In another exemplary embodiment, the electrode catheter determines the contact and coupling condition based at least in part on a phase angle of the impedance.
摘要:
This invention relates to new compounds that can serve as hypoxia mimetics. This invention also relates to methods of increasing HIF levels or activity in a subject or treating a condition associated with HIF levels or activity in a subject by administering to the subject at least one of these compounds.
摘要:
A curved ablation catheter imparts ablative energy to target tissue, for example, along a trabecular slope, e.g., in the right atrium along the isthmus between the ostium of the inferior vena cava and the tricuspid valve. The catheter is formed with a preset curvature that, when deployed, both translates linearly and increases in radius to aid in the formation of spot or continuous linear lesions. A method of treating atrial flutter employs the curved ablation catheter.
摘要:
An ablation catheter is provided for ablating internal tissue of a patient. The catheter includes a distal end that is adapted to be inserted into a body cavity relative to a desired location therein (e.g., within the heart). An ablation electrode is connected relative to the distal end of the catheter for providing ablation energy to patient tissue. A heat sink is provided that is in thermal contact with the ablation electrode. The heat sink, in addition to being in thermal contact with the ablation electrode, is electrically isolated from the ablation electrode. This allows the heat sink to conduct heat away from the ablation electrode without dissipating electrical energy from the electrode. In this regard, the heat sink may prevent build-up of excess heat within the electrode that may result in blood coagulation and/or tissue charring.
摘要:
Systems and methods are disclosed for assessing electrode-tissue contact for tissue ablation. An exemplary electrode contact sensing system comprises an electrode housed within a distal portion of a catheter shaft. At least one electro-mechanical sensor is operatively associated with the electrode within the catheter shaft. The at least one electro-mechanical sensor is responsive to movement of the electrode by generating electrical signals corresponding to the amount of movement. The system may also include an output device electrically connected to the at least one electro-mechanical sensor. The output device receives the electrical signals for assessing a level of contact between the electrode and a tissue.