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    Fluid dispenser having a one-way valve, pump, variable-volume storage chamber, and a needle penetrable and laser resealable portion
    1.
    发明申请
    Fluid dispenser having a one-way valve, pump, variable-volume storage chamber, and a needle penetrable and laser resealable portion 有权
    流体分配器具有单向阀，泵，可变容积储存室，以及针可穿透和激光可再密封部分

    公开(公告)号：US20060131338A1

    公开(公告)日：2006-06-22

    申请号：US11351716

    申请日：2006-02-10

    Applicant: Daniel Py ,  Joseph Ting

    Inventor： Daniel Py ,  Joseph Ting

    IPC: B67D5/06

    CPC classification number: B65D83/0055 ,  A61F9/0008 ,  B05B11/00412 ,  B05B11/0072 ,  B05B11/0097 ,  B05B11/3004 ,  B05B11/3074 ,  B05B11/3077 ,  B05B11/3092 ,  B05B11/3094 ,  B65D81/245

    Abstract: A dispenser for dispensing a fluid includes a rigid vial that has a main fluid chamber containing a fluid, and a pump assembly that is in fluid communication with the main fluid chamber and is configured to dispense a predetermined quantity of fluid from the main fluid chamber. A flexible bladder is provided which is located within the main fluid chamber and is configured to expand to fill the ullage created within the main fluid chamber during dispensing of fluid by the pump assembly. The resilient bladder tends to force itself outwardly toward the rigid vial and, in turn, increases the pressure within the main fluid chamber in comparison to the interior of the bladder to thereby prevent the ingress of air or vapors through the bladder or otherwise into the main fluid chamber.

    Abstract translation: 用于分配流体的分配器包括具有包含流体的主流体室的刚性小瓶和与主流体室流体连通并被构造成从主流体室分配预定量的流体的泵组件。 提供柔性囊，其位于主流体室内并且构造成膨胀以填充由泵组件分配流体期间在主流体室内产生的空位。 弹性气囊趋于朝向刚性小瓶向外强制，并且与气囊的内部相比增加了主流体室内的压力，从而防止空气或蒸气进入气囊或以其它方式进入主体 流体室。

    Ophthalmic dispenser and associated method
    2.
    发明申请
    Ophthalmic dispenser and associated method 有权
    眼科分配器及相关方法

    公开(公告)号：US20050029307A1

    公开(公告)日：2005-02-10

    申请号：US10691270

    申请日：2003-10-21

    Applicant: Daniel Py ,  Norbert Assion ,  Julian Chan ,  Joseph Ting

    Inventor： Daniel Py ,  Norbert Assion ,  Julian Chan ,  Joseph Ting

    IPC: B67D7/60 ,  A61F9/00 ,  B05B11/00 ,  B65D81/24 ,  B67D7/84 ,  B67D5/42

    CPC classification number: A61F9/0008 ,  B05B11/00412 ,  B05B11/0054 ,  B05B11/0072 ,  B05B11/0097 ,  B05B11/3092 ,  B05B11/3094 ,  B65B3/003 ,  B65D81/245 ,  Y10T29/49826

    Abstract: An ophthalmic dispenser has a rigid housing defining a fluid-receiving chamber, a flexible bladder receivable within the fluid-receiving chamber, a pump coupled in fluid communication with the fluid-receiving chamber, and a nozzle having a valve defining an annular, axially-extending valve seat, an outlet aperture coupled in fluid communication between the valve seat and the pump, and a flexible valve cover extending about the valve seat and forming an annular, axially-extending interface therebetween. The valve interface is connectable in fluid communication with the outlet aperture, and at least part of the valve cover is movable between (i) a normally closed position with the valve cover engaging the valve seat to close the interface and form a fluid-tight seal therebetween, and (ii) an open position with at least part of the valve cover spaced away from the valve seat in response to pumped fluid flowing through the outlet aperture at a pressure greater than a valve opening pressure to allow the passage of pressurized fluid therebetween. A spring is drivingly connected to the housing and moves at least one of the pump and housing relative to the other to actuate the pump. The rigid housing is mountable within a cartridge which, in turn, is mountable within a dispenser housing including an eyelid depressor and a trigger for simultaneously actuating the eyelid depressor and pump.

    Abstract translation: 眼科分配器具有限定流体接收室的刚性壳体，可接收在流体接收室内的柔性气囊，与流体接收室流体连通的泵，以及具有限定环形轴向 - 延伸阀座，联接在阀座和泵之间流体连通的出口孔，以及围绕阀座延伸并在其间形成环形的轴向延伸的接口的柔性阀盖。 阀接口可连接到出口孔流体连通，并且阀盖的至少一部分可在（i）常闭位置与阀盖之间移动，阀盖与阀座接合以闭合界面并形成流体密封 ，并且（ii）打开位置，其中阀盖的至少一部分响应于在大于阀打开压力的压力下流过出口孔的泵送流体而与阀座间隔开，以允许加压流体在其间通过 。 弹簧驱动地连接到壳体并且相对于另一个移动泵和壳体中的至少一个以致动泵。 刚性壳体可安装在盒中，其又可安装在分配器壳体内，该分配器壳体包括用于同时致动眼睑下压器和泵的眼睑下压器和触发器。

    Single use connectors
    3.
    发明授权
    Single use connectors 有权

    公开(公告)号：US10426701B2

    公开(公告)日：2019-10-01

    申请号：US15410762

    申请日：2017-01-19

    Applicant: Daniel Py

    Inventor： Daniel Py

    IPC: A61J1/20 ,  A61M5/162 ,  A61M39/10 ,  A61M39/18 ,  A61M39/26

    Abstract: Connector assembly including a piercing member having a flow port therein attached to a first piece, with the piercing member slidingly receivable within a second piece, wherein the piercing member and the second pierce are movable relative to each other between a first position where the second pieces closes the flow port and a second position where the flow port is open. The first piece contains a locking mechanism that lockingly engages with a device when connected thereto, preventing subsequent disconnection of first piece and the device. Upon initial connection of the first piece to the device, the second piece is moved from the first position to the second position.

    Device with closure, one-way valve, and storage chamber and related method
    4.
    发明授权
    Device with closure, one-way valve, and storage chamber and related method 有权

    公开(公告)号：US09737435B2

    公开(公告)日：2017-08-22

    申请号：US13745721

    申请日：2013-01-18

    Applicant: Daniel Py

    Inventor： Daniel Py

    IPC: A61F9/00 ,  B23P15/00 ,  B05B11/00 ,  B65D83/00

    CPC classification number: A61F9/0008 ,  B05B11/0056 ,  B05B11/0062 ,  B05B11/0067 ,  B05B11/007 ,  B05B11/0097 ,  B23P15/001 ,  B65D83/0022 ,  Y10T29/49412

    Abstract: A device has a first part with a valve seat and storage chamber, and a second part with a flexible valve cover and actuator. The storage chamber may be formed from a pre-form blow-molded into a flexible pouch defining a variable-volume storage chamber. The flexible valve cover and valve seat form a normally closed valve seam therebetween. The valve cover is movable in response to fluid at an inlet to the seam exceeding a valve opening pressure of the one-way valve between (i) a normally closed position with valve cover and valve seat in contact with each other and defining the normally closed seam, and (ii) a second position with at least a portion of the valve cover spaced away from the valve seat to allow the fluid to pass through the seam. The one-way valve may have anti-spritz features for using the device to dispense a substance, such as to the eye. The device may contain prostaglandins without the device material absorbing the prostaglandins material and/or without the material being adsorbed into the drug.

    Closure for a device with a base and a support
    7.
    发明授权
    Closure for a device with a base and a support 有权
    关闭设备与基地和支持

    公开(公告)号：US09211983B2

    公开(公告)日：2015-12-15

    申请号：US13847277

    申请日：2013-03-19

    Applicant: Daniel Py

    Inventor： Daniel Py

    IPC: B65D35/56 ,  B65D47/24 ,  B65D23/02 ,  B65D47/32 ,  B05B11/00 ,  B29C47/00 ,  B29C47/06 ,  B29C49/04 ,  B29L9/00 ,  B29L31/00

    CPC classification number: B65D47/24 ,  B05B11/3028 ,  B29C47/0021 ,  B29C47/0023 ,  B29C47/0026 ,  B29C47/065 ,  B29C47/068 ,  B29C49/04 ,  B29L2009/00 ,  B29L2031/7158 ,  B65D23/02 ,  B65D47/205 ,  B65D47/32

    Abstract: A device comprises a first portion including a first polymer, and a second portion that is relatively flexible in comparison to the first portion and includes a second polymer that is substantially not bondable to the first polymer. A chamber of the device is hermetically sealable with respect to ambient atmosphere and is defined by (i) an interior of the second portion, and/or (ii) a space formed between the first and second portions. A third portion of the device includes a third polymer that is bondable to the first and second polymers and fixedly secures the first and second portions to each other.

    Abstract translation: 一种装置包括包含第一聚合物的第一部分和与第一部分相比具有相对柔性的第二部分，并且包括基本上不能与第一聚合物结合的第二聚合物。 该装置的腔室相对于环境气氛可气密地密封，并且由（i）第二部分的内部和/或（ii）形成在第一和第二部分之间的空间限定。 该装置的第三部分包括可与第一和第二聚合物结合的第三聚合物，并将第一和第二部分彼此固定地固定。

    ONE-WAY VALVE AND APPARATUS AND METHOD OF USING THE VALVE
    8.
    发明申请
    ONE-WAY VALVE AND APPARATUS AND METHOD OF USING THE VALVE 有权
    单向阀和装置以及使用阀的方法

    公开(公告)号：US20140246462A1

    公开(公告)日：2014-09-04

    申请号：US14101981

    申请日：2013-12-10

    Applicant: Daniel Py ,  Julian V. Chan ,  Benoit Adamo ,  Nathaniel Houle

    Inventor： Daniel Py ,  Julian V. Chan ,  Benoit Adamo ,  Nathaniel Houle

    IPC: B65D37/00

    CPC classification number: B67D1/108 ,  B05B11/00444 ,  B65B39/004 ,  B65D51/002 ,  B65D51/1616 ,  B67D1/0004 ,  B67D1/0007 ,  B67D1/0009 ,  B67D1/0082 ,  B67D1/0801 ,  B67D1/10 ,  B67D1/1279 ,  B67D3/0067 ,  B67D3/04 ,  B67D2001/0827 ,  F04B53/1037

    Abstract: A flexible pouch and valve assembly is provided for aseptically storing a substance, dispensing multiple portions of the stored substance therefrom, and maintaining substance remaining in the pouch in an aseptic condition sealed with respect to ambient atmosphere. The flexible pouch and valve assembly are receivable within a relatively rigid housing, and are adapted to cooperate with a pump for pumping discrete portions of substance from the pouch and through the one-way valve to dispense the substance therefrom. The assembly comprises a flexible pouch defining therein a variable-volume storage chamber sealed with respect to the ambient atmosphere for aseptically storing therein multiple portions of the substance. A one-way valve of the assembly includes a valve body defining an axially-extending valve seat and at least one flow aperture extending through the valve body and/or the valve seat.

    Abstract translation: 提供了一种柔性袋和阀组件，用于无菌存储物质，从其中分配多部分储存物质，并将残留在袋中的物质保持在相对于环境大气密封的无菌状态。 柔性袋和阀组件可接收在相对刚性的壳体内，并且适于与泵协作，用于泵送物质的离散部分并且通过单向阀从其分配物质。 组件包括柔性袋，其中限定有相对于环境大气密封的可变容积存储室，用于将物质的多个部分无菌存储。 组件的单向阀包括限定轴向延伸的阀座的阀体和延伸穿过阀体和/或阀座的至少一个流动孔。

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