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公开(公告)号：USRE29725E
公开(公告)日：1978-08-08
申请号：US35438
申请日：1970-05-07
IPC分类号： B01L3/00 , B01L3/14 , C12Q1/00 , G01N21/03 , G01N21/25 , G01N33/487 , G01N33/52 , G01N35/00 , G01N35/02 , G01N35/04 , G01N35/10
CPC分类号： B01L3/5453 , B01L3/502 , C12Q1/00 , G01N21/03 , G01N21/253 , G01N33/528 , G01N35/00 , G01N35/02 , B01L2200/16 , B01L2300/0867 , B01L2400/0683 , B01L3/505 , G01N2035/0436 , G01N35/1079 , Y10T436/144444 , Y10T436/171538
摘要： Performing analytical tests more easily, quickly and accurately by using a specially designed pouch-like container of pliable material. The container has within it a plurality of compartments, each compartment being capable of containing a different reagent and each compartment also being capable of releasing its contained reagent, independently of any other reagents present in the other compartments, into the area of the container not occupied by compartments. This latter area of the container is also adapted to receive the test sample for reaction with any single reagent or any combination of reagents released from the compartments.
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公开(公告)号：US4066412A
公开(公告)日：1978-01-03
申请号：US753197
申请日：1968-08-16
IPC分类号： B01L3/00 , B01L3/14 , G01N33/487 , G01N33/52 , G01N35/00 , G01N35/02 , G01N35/04 , G01N35/10 , G01N33/16 , G01N21/24
CPC分类号： B01L3/502 , B01L3/5453 , G01N33/52 , G01N35/00 , G01N35/021 , G01N2035/0436 , G01N35/1079
摘要： An apparatus for automatically performing analytic procedural steps on a fluid contained in a disposable deformable test pack. The apparatus consists of a means for filling the test pack with sample fluid, a means for controlling the environment of the test pack, a means for initiating reactions within the test pack, a means for analyzing the fluid in the test pack, and a transport means designed to hold the test pack and to transport it between the various operating stations. Associated circuitry combining method switchng and control logic make the operation of the instrument fully automatic.
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公开(公告)号：US5453252A
公开(公告)日：1995-09-26
申请号：US201797
申请日：1994-02-25
申请人： William L. Truett
发明人： William L. Truett
CPC分类号： G01N21/03 , G01N21/3563 , G01N2021/0346
摘要： A specimen support for optical observation or analysis is disclosed. The support comprises a disc-like member composed of a rigid material and having a plurality of holes extending therethrough, preferably in a screen of substantially equal-sized holes. When analyzing a liquid specimen, the disc is dipped in the liquid and the surface tension of the liquid will cause the liquid to bridge or span the holes. The support is then placed vertically in a tray or holder and exposed to an infrared beam that passes horizontally through the holes to generate an infrared spectrum.
摘要翻译： 公开了用于光学观察或分析的样本支架。 支撑件包括由刚性材料构成并且具有延伸穿过其中的多个孔的盘状构件，优选地在基本上相等尺寸的孔的筛网中。 当分析液体样品时，将盘浸入液体中，并且液体的表面张力将导致液体桥接或跨越孔。 然后将支撑物垂直放置在托盘或保持器中并暴露于水平穿过孔的红外光束以产生红外光谱。
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公开(公告)号：US5905144A
公开(公告)日：1999-05-18
申请号：US929475
申请日：1997-09-15
申请人： William L. Truett
发明人： William L. Truett
IPC分类号： C07D499/00 , C07D499/46 , C07D501/00 , C07D501/22 , C07H19/056 , C07H19/16 , A61K31/70
CPC分类号： C07H19/16 , C07D499/00 , C07D501/00 , C07H19/056
摘要： A series of novel antivirals are disclosed intended to attack a broad range of DNA and RNA viruses, in which nucleosides closely related entities are linked via reaction with a diacid chloride of the general structure COCl--(CH.sub.2).sub.n --COCl wherein n is two or greater.
摘要翻译： 公开了一系列新颖的抗病毒药物，旨在攻击广泛的DNA和RNA病毒，其中核苷密切相关的实体通过与通式结构CO 2 - （CH 2）n -COCl的二酰氯反应而连接，其中n为2或 更大
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公开(公告)号：US5728301A
公开(公告)日：1998-03-17
申请号：US638337
申请日：1996-04-26
申请人： William L. Truett
发明人： William L. Truett
CPC分类号： G01N30/95
摘要： A method for spectral analysis of mixtures is disclosed using thin layer chromatography for separation of the components of the mixture followed by taking FTIR spectroscopic readings along the vertical length of the coated support.
摘要翻译： 公开了一种用于混合物光谱分析的方法，其中使用薄层色谱法分离混合物的组分，随后沿着涂覆的载体的垂直长度进行FTIR光谱读数。
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公开(公告)号：US5693791A
公开(公告)日：1997-12-02
申请号：US420302
申请日：1995-04-11
申请人： William L. Truett
发明人： William L. Truett
IPC分类号： C07D499/00 , C07D499/46 , C07D501/00 , C07D501/22 , C07H19/056 , C07H19/16 , C07D501/46 , A61K31/545
CPC分类号： C07H19/16 , C07D499/00 , C07D501/00 , C07H19/056
摘要： A group of reagents, as diisocyanates, dianhydrides, diacidchlorides, diepoxides, carbodiimides and the like are utilized to link a wide variety of antibiotic moities, reacted two at a time with said reagents, the said antibiotic moieties containing groups reactive with the linking reagents as carboxylic acid, alcolhol, primary amine, and secondary amine functional groups, said functional groups being present as singularities or as multiplicities, products being readily purified using chromatographic techniques, and said products of above reactions being valuable for the treatment of microbial infections of man and animals.
摘要翻译： 使用一组作为二异氰酸酯，二酐，二酰氯，二环氧化物，碳二亚胺等的试剂连接多种抗生素，每次两次与所述试剂反应，所述抗生素部分含有与连接试剂反应的基团作为 羧酸，醇，伯胺和仲胺官能团，所述官能团以奇异性或多重性存在，使用色谱技术容易地纯化产物，并且上述反应的产物对于治疗人的微生物感染和 动物。
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公开(公告)号：US5677191A
公开(公告)日：1997-10-14
申请号：US523275
申请日：1995-09-05
申请人： William L. Truett
发明人： William L. Truett
CPC分类号： G01N21/3563 , G01N2021/3595 , Y10T436/20 , Y10T436/200833 , Y10T436/201666 , Y10T436/203332
摘要： A series of organic test papers are described for the detection and identification of all types of organic compounds such as aldehydes, ketones, esters, acids, amines, isocyanates, anhydrides, amides, nitrides, aromatics, phenols, ethers, and other organic compounds, said test papers comprising an absorbent paper or microporous plastic impregnated with a reagent or reagents capable of reacting with a class of organic compounds. The method of using the test papers for the identification of organic compounds comprises making a presumptive identification of the class of the unknown sample using FTIR spectroscopy, and then placing this presumptively identified sample onto the paper to generate a new substance known as a derivative of the organic compound, which aids in the identification of the unknown organic compound. The test paper containing said sample and reagent is then monitored again using FTIR spectroscopy to observe the reaction and to verify the presumptively identified substance's class identification.
摘要翻译： 描述了一系列有机测试纸，用于检测和鉴定所有类型的有机化合物如醛，酮，酯，酸，胺，异氰酸酯，酸酐，酰胺，氮化物，芳族化合物，酚，醚和其它有机化合物， 所述测试纸包括浸渍有能够与一类有机化合物反应的试剂或试剂的吸收纸或微孔塑料。 使用测试纸来鉴别有机化合物的方法包括使用FTIR光谱法来推测未知样品的类别，然后将该推定的样品置于纸上以产生被称为衍生物的新物质 有机化合物，有助于鉴定未知的有机化合物。 然后使用FTIR光谱仪再次监测含有所述样品和试剂的试纸，以观察反应并验证推定的物质的类别鉴定。
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公开(公告)号：US5519219A
公开(公告)日：1996-05-21
申请号：US303174
申请日：1994-09-08
CPC分类号： G01N21/3504 , G01N21/3563 , G01N21/3577 , G01N2201/0221 , G01N2201/0693
摘要： There is described within a portable, battery-powered multiple filter infrared spectrometer consisting of a highly efficient optical system employing an infrared source with a chopper, from which IR energy passes through compound parabolic concentrators (CPC's) and is directed by a beamsplitter to the external sample, where the beam intersects with the sample via reflection and is returned through the CPC and beamsplitter to a stationary filter assembly and discrete detector array where the energy is converted to an A.C. (alternating current) signal. This current energizes an LED bar graph display for spectral identification. This method and apparatus is used to determine IR spectra of solids, liquids on a mirror, and gases in a container with a mirror to reflect light.
摘要翻译： 在由便携式电池供电的多重滤波器红外光谱仪中描述，其包括使用具有斩光器的红外源的高效光学系统，IR能量通过复合抛物面聚光器（CPC）并由分束器引导到外部 样品，其中光束通过反射与样品相交，并通过CPC和分束器返回到固定的过滤器组件和离散检测器阵列，其中能量被转换为AC（交流）信号。 该电流激励LED条形图显示以进行光谱识别。 该方法和装置用于确定固体，反射镜上的液体和具有反射光的反射镜的容器中的气体的IR光谱。
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公开(公告)号：US5723341A
公开(公告)日：1998-03-03
申请号：US675553
申请日：1996-07-03
申请人： William L. Truett
发明人： William L. Truett
CPC分类号： G01N21/03 , G01N21/3563 , G01N2021/0346 , Y10T436/25
摘要： A method of analyzing a specimen by infrared spectroscopy is disclosed wherein a specimen support having a plurality of unobstructed holes of substantially uniform size and a film of the specimen enclosing each hole is positioned vertically in the spectrometer and a beam of infrared light is directed through the holes to generate a wavelength spectrum characteristic of the specimen.
摘要翻译： 公开了一种通过红外光谱法分析样品的方法，其中具有多个基本均匀尺寸的无阻挡孔的样品支架和包围每个孔的试样膜被垂直放置在光谱仪中，并且一束红外光被引导通过 孔以产生样品的波长谱特征。
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公开(公告)号：US5519220A
公开(公告)日：1996-05-21
申请号：US267413
申请日：1994-06-28
申请人： William L. Truett
发明人： William L. Truett
CPC分类号： G01N21/3577 , G01N2021/3595
摘要： The device of the invention employs a small Teflon.RTM. vial which is mounted in a vertical position in a plastic box, and a segment of screen attached to a rod which can be raised or lowered into the reaction vessel which contains liquid reactants. When raised, the screen carries a sample into a portion of the vessel having IR transparent parts, axially aligned with corresponding parts in the plastic outer container. The device is positioned in an FTIR spectrometer. Data obtained from successive IR scans are used to follow the progress of a chemical reaction.
摘要翻译： 本发明的装置采用安装在塑料箱中的垂直位置的小型特氟纶TM小瓶，以及连接到可以升高或降低到包含液体反应物的反应容器中的杆的筛网段。 当升高时，筛子将样品运送到具有IR透明部分的容器的一部分中，与塑料外容器中的相应部件轴向对齐。 该装置位于FTIR光谱仪中。 使用从连续IR扫描获得的数据来跟踪化学反应的进展。
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