公开(公告)号：US5728317A

公开(公告)日：1998-03-17

申请号：US647877

申请日：1996-05-13

申请人： Gerhard Laqua ,  Franz Merger ,  Tom Witzel ,  Ursula Siebenhaar ,  David Agar

发明人： Gerhard Laqua ,  Franz Merger ,  Tom Witzel ,  Ursula Siebenhaar ,  David Agar

IPC分类号： C07C263/18 ,  C07C265/14 ,  C08G18/73 ,  C08G18/75 ,  C08G18/79 ,  C08K5/00 ,  C09K3/00 ,  C07C249/00 ,  C07C251/00 ,  C07C257/00

CPC分类号： C08G18/792 ,  C07C263/18 ,  C07C265/14 ,  C08G18/022 ,  C08G18/092 ,  C08G18/73 ,  C08G18/75 ,  C08K5/005 ,  C07C2101/14

摘要： (Cyclo)aliphatic polyisocyanate compositions which have a long shelf life, are obtainable by phosgene-free methods, preferably by thermal cleavage of (cyclo)aliphatic polycarbamates, and, for stabilization, contain at least one primary stabilizer (2a), preferably a sterically hindered phenol and/or an aromatic amine, or at least one secondary stabilizer (2b), preferably an organic phosphite and/or a thioether, or at least one acidic stabilizer (2c), preferably a carboxylic acid, an acyl chloride, an inorganic acid, an inorganic acid chloride and/or a diester of phosphoric acid, or a stabilizer system comprising at least 2 of the stabilizers (2a) to (2c), a process for the preparation of the (cyclo)aliphatic polyisocyanate compositions and their preferred use for the preparation of isocyanurate-containing polyisocyanates.

摘要翻译： 具有长保质期的（Cyclo）脂族多异氰酸酯组合物可通过无光气的方法获得，优选通过（环）脂族聚氨基甲酸酯的热裂解获得，并且为了稳定，含有至少一种主要稳定剂（2a），优选为空间 受阻酚和/或芳族胺，或至少一种仲级稳定剂（2b），优选有机亚磷酸酯和/或硫醚，或至少一种酸性稳定剂（2c），优选羧酸，酰氯，无机 酸，无机酰氯和/或磷酸二酯，或包含至少2种稳定剂（2a）至（2c）的稳定剂体系，制备（环）脂族多异氰酸酯组合物及其优选的 用于制备含异氰脲酸酯的多异氰酸酯。

公开(公告)号：US5489663A

公开(公告)日：1996-02-06

申请号：US356084

申请日：1994-12-15

申请人： Peter Brandt ,  Bernd Bruchmann ,  Gerhard Laqua ,  Franz Merger ,  Andreas Otterbach ,  Konrad Stiefenhofer ,  Tom Witzel ,  Stefan Wolff ,  Rainer Becker

发明人： Peter Brandt ,  Bernd Bruchmann ,  Gerhard Laqua ,  Franz Merger ,  Andreas Otterbach ,  Konrad Stiefenhofer ,  Tom Witzel ,  Stefan Wolff ,  Rainer Becker

IPC分类号： B01J20060101 ,  B01J31/02 ,  C07B61/00 ,  C07D20060101 ,  C07D251/34 ,  C08G20060101 ,  C08G18/02 ,  C08G18/18 ,  C08G18/79 ,  C09D20060101 ,  C08G18/20 ,  C08G18/16

CPC分类号： C07D251/34 ,  C08G18/792

摘要： Polyisocyanates containing isocyanurate groups are prepared by a partial trimerization of (cyclo)aliphatic diisocyanates in the presence of at least one trimerization catalyst selected from the group consisting of tetraalkylammonium alkyl carbonates of the formula (I) ##STR1## (quaternary ammonioalkyl) carbonates having a betaine structure of the formula (II) ##STR2## and the preferred use of the polyisocyanates containing isocyanurate groups which are obtainable in this way is aspolyisocyanate component in polyurethane finishes.

摘要翻译： 含有异氰脲酸酯基的多异氰酸酯是通过在至少一种选自式（I）的四烷基烷基碳酸酯（I）（季铵烷基））的三聚催化剂存在下，通过（环）脂族二异氰酸酯的部分三聚制备的， 具有式（II）的甜菜碱结构的碳酸酯（II）和以这种方式获得的含有异氰脲酸酯基团的多异氰酸酯的优选用途是聚氨酯涂料中的多异氰酸酯组分。

公开(公告)号：US5516928A

公开(公告)日：1996-05-14

申请号：US395322

申请日：1995-02-28

申请人： Klaus Mundinger ,  Gerhard Laqua ,  Tom Witzel ,  Franz Merger

发明人： Klaus Mundinger ,  Gerhard Laqua ,  Tom Witzel ,  Franz Merger

IPC分类号： C07C253/10 ,  C07C255/46

CPC分类号： C07C253/10 ,  C07C2101/14

摘要： A process for the preparation of 3-cyano-3,5,5-trimethylcyclohexanone by the reaction of isophorone with hydrogen cyanide in the presence of quaternary ammonium catalysts at temperatures ranging from 80.degree. to 180.degree. C. and pressures ranging from 0.5 to 20 bar, in which the ammonium catalysts used are salts of the general formula I ##STR1## in which R.sup.1, R.sup.2, R.sup.3, R.sup.4 denote C.sub.1 -C.sub.18 alkyl, C.sub.5 -C.sub.8 cycloalkyl, aryl, C.sub.7 -C.sub.18 aralkyl or C.sub.2 -C.sub.18 hydroxyalkyl andX denotes HCO.sub.3 or ##STR2## with the proviso that R.sup.4 stands for C.sub.1 -C.sub.8 alkyl when X is ##STR3##

摘要翻译： 在季铵催化剂存在下，通过异佛尔酮与氰化氢反应制备3-氰基-3,5,5-三甲基环己酮的方法，温度范围为80-180℃，压力范围为0.5-20 其中使用的铵催化剂是通式I的盐，其中R 1，R 2，R 3，R 4表示C 1 -C 18烷基，C 5 -C 8环烷基，芳基，C 7 -C 18芳烷基或C 2-8芳烷基， C18羟烷基，X表示HCO3或者“IMAGE”，条件是当X为时，R4代表C1-C8烷基，

公开(公告)号：US5166447A

公开(公告)日：1992-11-24

申请号：US776688

申请日：1991-10-15

申请人： Franz Merger ,  Tom Witzel

发明人： Franz Merger ,  Tom Witzel

IPC分类号： C07C45/60 ,  C07C49/395 ,  C07C49/523

CPC分类号： C07C49/395 ,  C07C45/60 ,  C07C49/523 ,  Y02P20/582

摘要： Cyclopentanones of the general formula I ##STR1## where R.sup.1 and R.sup.2 are each an organic radical or R.sup.1 or R.sup.2 may be hydrogen and R.sup.3 is hydrogen or formyl, are prepared by a process in which a 2-formyl-3,4-dihydropyran of the general formula II ##STR2## where R.sup.1 and R.sup.2 have the abovementioned meanings, a) where R.sup.3 is formyl, is converted in the presence of an acidic heterogeneous catalyst at from 50.degree. to 500.degree. C., andb) where R.sup.3 is hydrogen,b.sub.1) is reacted with water or an alcohol in the presence of an acidic heterogeneous catalyst at from 100.degree. to 500.degree. C. in the gas phase orb.sub.2) a compound II or an acrolein of the general formula III ##STR3## is reacted with water or with water in the presence of an acid or with an alcohol in the presence of an acid at from 150.degree. to 400.degree. C. in the liquid phase. Novel 2-formylcyclopentanones are obtained.

摘要翻译： 其中R 1和R 2各自为有机基团或R 1或R 2可以是氢并且R 3为氢或甲酰基的通式I（I）的环戊烷酮通过其中2-甲酰基-3,4 - 二氢吡喃，其中R 1和R 2具有上述含义，a）其中R 3是甲酰基，在酸性多相催化剂存在下在50-500℃下转化，和 b）其中R3是氢，b1）在酸性非均相催化剂存在下，在气相中在100-500℃下与水或醇反应，或b2）化合物II或通式为的丙烯醛 在酸的存在下，在酸的存在下，在液相中，在150℃至400℃的条件下，将III（III）化合物与水或水在酸或醇的存在下反应。 得到新的2-甲酰基环戊烷酮。

公开(公告)号：US5371292A

公开(公告)日：1994-12-06

申请号：US92029

申请日：1993-07-15

申请人： Franz Merger ,  Claus-Ulrich Priester ,  Tom Witzel ,  Gerhard Koppenhoefer ,  Wolfgang Harder

发明人： Franz Merger ,  Claus-Ulrich Priester ,  Tom Witzel ,  Gerhard Koppenhoefer ,  Wolfgang Harder

IPC分类号： B01J21/04 ,  B01J21/06 ,  B01J23/46 ,  B01J27/18 ,  C07B61/00 ,  C07C209/00 ,  C07C209/26 ,  C07C209/48 ,  C07C209/52 ,  C07C211/36 ,  C07C209/24

CPC分类号： C07C209/48 ,  C07C209/26 ,  C07C2101/14

摘要： A process for the preparation of 3-aminomethyl-3,5,5-trimethyl-cyclohexylamine from 3-cyano-3,5,5-trimethyl-cyclohexanone, wherein the following stages are carried out in discrete reaction chambers:a) the 3-cyano-3,5,5-trimethyl-cyclohexanone is reacted in a first reaction chamber with excess ammonia over an acidic metal oxide catalyst at a temperature of from 20.degree. to 150.degree. C. and a pressure of from 15 to 500 bar, andb) in a second reaction chamber, the reaction product from stage a) is hydrogenated with hydrogen at a temperature of from 60.degree. to 150.degree. C. and a pressure of from 50 to 300 bar in the presence of excess ammonia over a catalyst containing cobalt, nickel, ruthenium, and/or some other noble metal, which catalyst optionally contains a basic component or is supported by neutral or basic supporting material.

摘要翻译： 从3-氰基-3,5,5-三甲基 - 环己酮制备3-氨基甲基-3,5,5-三甲基 - 环己胺的方法，其中以下步骤在离散反应室中进行：a）3 氰基-3,5,5-三甲基 - 环己酮在第一反应室中与过量的氨在酸性金属氧化物催化剂上在20至150℃的温度和15至500巴的压力下反应， 和b）在第二反应室中，在过量的氨在催化剂存在下，将氢气从60℃升至150℃，压力为50-300巴，在步骤a）中的反应产物被氢化 含有钴，镍，钌和/或一些其它贵金属，该催化剂任选地含有碱性组分或由中性或碱性载体材料负载。

公开(公告)号：US5334745A

公开(公告)日：1994-08-02

申请号：US69129

申请日：1993-05-28

申请人： Martin Brudermueller ,  Tom Witzel ,  Franz Merger

发明人： Martin Brudermueller ,  Tom Witzel ,  Franz Merger

IPC分类号： C07C253/30

CPC分类号： C07C253/30

摘要： 3-Aminopropionitriles of the general formula I ##STR1## where R.sup.1,R.sup.2,R.sup.3,R.sup.4 and R.sup.5 independently of one another are each hydrogen, C.sub.1 -C.sub.20 -alkyl, C.sub.1 -C.sub.8 -aminoalkyl, C.sub.1 -C.sub.8 -cyanoalkyl, C.sub.3 -C.sub.20 -cycloalkyl, C.sub.7 -C.sub.20 -aralkyl or aryl,are prepared by a process in which an amine of the general formula II ##STR2## is reacted with an acrylonitrile of the general formula III ##STR3## where the substituents have the abovementioned meanings, in a molar ratio of from 0.9:1 to 100:1 over a heterogeneous catalyst at from 40.degree. to 200.degree. C. and from 1 to 350 bar.

摘要翻译： 其中R 1，R 2，R 3，R 4和R 5彼此独立地是通式I的化合物，其中R 1，R 2，R 3，R 4和R 5彼此独立地是氢，C 1 -C 20 - 烷基，C 1 -C 8 - 氨基烷基，C 1 -C 8 - 氰基烷基， C 3 -C 20 - 环烷基，C 7 -C 20 - 芳烷基或芳基，其中通式II的胺（II）与通式III的丙烯腈（III）反应的方法制备， 其中取代基具有上述含义，摩尔比为0.9:1至100:1，在多元催化剂中，在40至200℃和1至350巴。

公开(公告)号：US5202465A

公开(公告)日：1993-04-13

申请号：US904925

申请日：1992-06-26

申请人： Franz Merger ,  Tom Witzel ,  Martin Brudermueller

发明人： Franz Merger ,  Tom Witzel ,  Martin Brudermueller

IPC分类号： B01J21/02 ,  B01J21/06 ,  B01J29/06 ,  C07B61/00 ,  C07C67/297 ,  C07C69/16 ,  C07C69/28

CPC分类号： C07C67/297 ,  Y02P20/582

摘要： 2-Methylenepropane-1,3-diol dicarboxylates are prepared by reacting pentaerythritol tetracarboxylates on solid catalysts at elevated temperatures.

摘要翻译： 2-甲基丙烷-1,3-二醇二羧酸盐通过在固体催化剂上升高温度下使季戊四醇四羧酸酯反应来制备。

公开(公告)号：US5576449A

公开(公告)日：1996-11-19

申请号：US314955

申请日：1994-09-29

申请人： J urgen Frank ,  Johann-Peter Melder ,  Franz Merger ,  Tom Witzel

发明人： J urgen Frank ,  Johann-Peter Melder ,  Franz Merger ,  Tom Witzel

IPC分类号： C07D319/06

CPC分类号： C07D319/06

摘要： The preparation of 2-substituted but-2-ene-1,4-dial-4-acetals of the formula I ##STR1## in which the substituents R.sup.1 to R.sup.4 stand for hydrogen or C.sub.1 -C.sub.6 aliphatic radicals, and R.sup.2 and R.sup.3 or R.sup.1 and R.sup.2 are in each case common members of an aliphatic 4-membered to 7-membered ring, which can contain a hetero atom, and R.sup.5 denotes an alkyl, alkenyl, or alkynyl radical having from 1 to 12 C atoms, which can be substituted by cycloaliphatic, aromatic or heterocyclic radicals or by hydroxy, ether, thioether, acyl, alkylamino, carboxy, or carbalkoxy groups, an optionally substituted aryl radical or an alkoxy, alkylthio, or acyloxy group, whereina) glyoxal is caused to react with a 1,3-propanediol of the formula II ##STR2## in aqueous solution in the presence of an acid to form a monoacetal of the formula III ##STR3## is neutralized, and if necessary the components more readily volatile than the monoacetal III are distilled off,b) the monoacetal III obtained is caused to react with an aldehyde R.sup.5 CH.sub.2 --CHO in the presence of from 0.01 to 10 mol %, based on glyoxal, of a catalyst mixture of a secondary amine and an acid to form an aldol of the formula IV ##STR4## the components which are more volatile than the aldol IV being distilled off if necessary, andc) the aldol IV is dehydrated in the presence of a water-eliminating agent to form the product I,and novel hemiacetals of glyoxal monoacetals.

摘要翻译： 制备其中取代基R 1至R 4代表氢或C 1 -C 6脂族基团的式I I 2的2-取代的丁-2-烯-1,4-二甲氧基-4-缩醛，以及R 2和R 3 或者R 1和R 2各自为可以含有杂原子的脂肪族4元〜7元环的共同成员，R 5表示具有1〜12个C原子的烷基，烯基或炔基，其可以 被脂环族，芳族或杂环基取代，或被羟基，醚，硫醚，酰基，烷基氨基，羧基或烷氧基取代，任选取代的芳基或烷氧基，烷硫基或酰氧基，其中a）使乙二醛反应 与式II II的1,3-丙二醇在酸存在下在水溶液中形成式III的单缩醛中和，如果需要，组分比单缩醛更容易挥发 III蒸馏掉，b）使获得的单缩醛III与醛反应 在基于乙二醛的0.01至10mol％的存在下，将仲胺和酸的催化剂混合物形成式IV的醛醇，得到更具挥发性的组分 如果需要，醛醇IV被蒸馏，和c）醛醇IV在除水剂存在下脱水以形成产物I，和乙二醛单缩醛的新型半缩醛。

公开(公告)号：US5344983A

公开(公告)日：1994-09-06

申请号：US936084

申请日：1992-08-26

申请人： Tom Witzel ,  Eberhard Fuchs ,  Franz Merger ,  Claus-Ulrich Priester

发明人： Tom Witzel ,  Eberhard Fuchs ,  Franz Merger ,  Claus-Ulrich Priester

IPC分类号： B01J23/40 ,  B01J23/755 ,  B01J27/10 ,  B01J27/125 ,  B01J27/18 ,  C07B61/00 ,  C07C209/48 ,  C07C211/09 ,  C07C209/00

CPC分类号： C07C209/48

摘要： Process for preparing a pentane-1,5-diamine of the formula ##STR1## where R.sup.1 represents a variety of organic radicals including alkyl which can bear substituents such as hydroxyl, halogen, alkoxy, carbalkoxy, carboxyl, alkylamino, cycloalkyl or aryl, andR.sup.2 and R.sup.3 independently of one another, represent hydrogen or have the same meanings as R.sup.1 or together are a C.sub.4 -C.sub.7 -alkylene chain which is unsubstituted or substituted by one to five C.sub.1 -C.sub.4 -alkyl groups,which comprises:(a) reacting a .gamma.-cyanoketone of the formula ##STR2## where R.sup.1, R.sup.2 and R.sup.3 have the meanings given above, with excess ammonia in a first reaction space on an acidic heterogeneous catalyst at 20.degree.-150.degree. C. and 15-500 bar, and(b) hydrogenating the resulting reaction product in a second separate reaction space in the presence of excess ammonia on a cobalt, nickel or noble metal catalyst at 50.degree.-180.degree. C. and 30-500 bar.Novel pentane-1,5-diamines are obtained, in which R.sup.1 must contain at least two carbon atoms if R.sup.2 and R.sup.3 are both hydrogen. These new compounds containing two primary amine groups possess advantageous properties of lower volatility and also greater asymmetry (with different reactivity of the two amine functions). They provide useful curing agents for epoxides and act as improved components of polyamides.

摘要翻译： 制备式（I）的戊烷-1,5-二胺的方法，其中R 1表示各种有机基团，包括可以带有取代基的烷基，例如羟基，卤素，烷氧基，烷氧基，羧基，烷基氨基，环烷基或 芳基和R 2和R 3彼此独立地表示氢或具有与R 1相同的含义或一起是未被取代或被一至五个C 1 -C 4 - 烷基取代的C 4 -C 7亚烷基链，其包含：（ a）在20-150℃的酸性非均相催化剂的第一反应空间中使具有上述含义的式（Ia）的式（II）的γ-氰基酮与过量的氨反应，其中R1，R2和R3具有上述含义， 15-500巴，（b）在钴，镍或贵金属催化剂的存在下，在50-180℃和30-500巴下，在第二分开的反应空间中，使得到的反应产物氢化。 得到新的戊烷-1,5-二胺，如果R2和R3都是氢，其中R1必须含有至少两个碳原子。 这些含有两个伯胺基团的新化合物具有较低的挥发性和更大的不对称性（两种胺官能团的不同反应性）的有利特性。 它们为环氧化物提供有用的固化剂，并且作为聚酰胺的改进组分。

公开(公告)号：US5166443A

公开(公告)日：1992-11-24

申请号：US676086

申请日：1991-03-17

申请人： Franz Merger ,  Claus-Ulrich Priester ,  Tom Witzel ,  Gerhard Koppenhoefer ,  Ludwig Schuster

发明人： Franz Merger ,  Claus-Ulrich Priester ,  Tom Witzel ,  Gerhard Koppenhoefer ,  Ludwig Schuster

IPC分类号： B01J23/40 ,  B01J23/74 ,  B01J29/06 ,  C07B61/00 ,  C07C209/48 ,  C07C211/09

CPC分类号： C07C209/48 ,  C07C211/09

摘要： A process for the preparation of a 2,2-disubstituted pentane-1,5-diamine of the formula I ##STR1## where R.sup.1 and R.sup.2, independently of one another, are C.sub.1 - to C.sub.10 -alkyl or C.sub.2 - to C.sub.10 -alkenyl or together are a C.sub.4 - to C.sub.7 -alkylene chain which is unsubstituted or monosubstituted to pentasubstituted by C.sub.1 - to C.sub.4 -alkyl, from a 2,2-disubstituted 4-cyanobutanal of the formula II ##STR2## where R.sup.1 and R.sup.2 are as defined above, comprises, in two spatially separate reaction spaces,a) reacting the 4-cyanobutanal of the formula II, in a first reaction space, with excess ammonia on an acidic heterogeneous catalyst at from 20.degree. to 150.degree. C. and at from 15 to 500 bar, andb) hydrogenating the resultant reaction product, in a second reaction space, using excess hydrogen in the presence of excess ammonia on a catalyst containing cobalt, nickel, ruthenium and/or another noble metal, if desired with a basic component or on a basic or neutral carrier, at from 60.degree. to 150.degree. C. and at from 50 to 500 bar.

摘要翻译： 制备式I（I）的2,2-二取代戊烷-1,5-二胺的方法，其中R 1和R 2彼此独立地为C 1至C 10烷基或C 2至 C10链烯基或一起是未被取代或被C1至C4-烷基单取代至五取代的C 4 -C 7亚烷基链，其由式II（II）的2,2-二取代4-氰基丁醛代替，其中 R1和R2如上定义，在两个空间上分开的反应空间中包含a）在第一反应空间中使式II的4-氰基丁醛与过量的氨在20-150℃的酸性多相催化剂上反应 和b）在第二反应空间中，在过量的氨存在下，使用过量的氢在含有钴，镍，钌和/或其它贵金属的催化剂上氢化所得反应产物， 如果需要，可以使用碱性组分或碱性或中性载体，在60至150℃和50至50℃ 500吧。