专利检索 ap:("Jingyue Ju" OR "Shiv Kumar" OR "Chuanjuan Tao" OR "Sergey Kalachikov" OR "James J. Russo") AND inv:"Jingyue Ju" 第 1 页

1.

发明授权
Synthesis of novel disulfide linker based nucleotides as reversible terminators for DNA sequencing by synthesis 有权

公开(公告)号：US11085076B2

公开(公告)日：2021-08-10

申请号：US15763364

申请日：2016-09-28

申请人： Jingyue Ju , Xiaoxu Li , Xin Chen , Zengmin Li , Shiv Kumar , Shundi Shi , Cheng Guo , Jianyi Ren , Min-Kang Hsieh , Minchen Chien , Chuanjuan Tao , Ece Erturk , Sergey Kalachikov , James J. Russo

发明人： Jingyue Ju , Xiaoxu Li , Xin Chen , Zengmin Li , Shiv Kumar , Shundi Shi , Cheng Guo , Jianyi Ren , Min-Kang Hsieh , Minchen Chien , Chuanjuan Tao , Ece Erturk , Sergey Kalachikov , James J. Russo

IPC分类号： C12Q1/68 , C07H19/10 , C07H19/14 , C07H19/20 , C12Q1/6869

摘要： Disclosed herein, inter alia, are compounds, compositions, and methods of use thereof in the sequencing of a nucleic acid.

2.

发明授权
DNA sequencing by synthesis using modified nucleotides and nanopore detection 有权

公开(公告)号：US11499186B2

公开(公告)日：2022-11-15

申请号：US16653278

申请日：2019-10-15

申请人： Jingyue Ju , Shiv Kumar , Zengmin Li , Chuanjuan Tao , Minchen Chien , James J. Russo , Sergey Kalachikov , Ken Shepard , Jacob Karl Rosenstein

发明人： Jingyue Ju , Shiv Kumar , Zengmin Li , Chuanjuan Tao , Minchen Chien , James J. Russo , Sergey Kalachikov , Ken Shepard , Jacob Karl Rosenstein

IPC分类号： C12Q1/68 , C12Q1/6869 , C07H19/10 , C07H21/00 , G01N33/487

摘要： This disclosure is related to a method of sequencing a single-stranded DNA using deoxynucleotide polyphosphate analogues and translocation of tags from incorporated deoxynucleotide polyphosphate analogues through a nanopore.

3.

发明授权
DNA sequencing by synthesis using modified nucleotides and nanopore detection 有权

公开(公告)号：US10443096B2

公开(公告)日：2019-10-15

申请号：US13994431

申请日：2011-12-16

申请人： Jingyue Ju , Shiv Kumar , Zengmin Li , Chuanjuan Tao , Minchen Chien , James J. Russo , Sergey Kalachikov , Ken Shepard , Jacob Karl Rosenstein

发明人： Jingyue Ju , Shiv Kumar , Zengmin Li , Chuanjuan Tao , Minchen Chien , James J. Russo , Sergey Kalachikov , Ken Shepard , Jacob Karl Rosenstein

IPC分类号： C12Q1/68 , C12Q1/6869 , C07H19/10 , C07H21/00 , G01N33/487

摘要： This disclosure is related to a method of sequencing a single-stranded DNA using deoxynucleotide polyphosphate analogues and translocation of tags from incorporated deoxynucleotide polyphosphate analogues through a nanopore.

4.

发明授权
Synthesis of novel disulfide linker based nucleotides as reversible terminators for DNA sequencing by synthesis 有权

公开(公告)号：US11999999B2

公开(公告)日：2024-06-04

申请号：US17373295

申请日：2021-07-12

申请人： Jingyue Ju , Xiaoxu Li , Xin Chen , Zengmin Li , Shiv Kumar , Shundi Shi , Cheng Guo , Jianyi Ren , Min-Kang Hsieh , Minchen Chien , Chuanjuan Tao , Ece Erturk , Sergey Kalachikov , James J. Russo

发明人： Jingyue Ju , Xiaoxu Li , Xin Chen , Zengmin Li , Shiv Kumar , Shundi Shi , Cheng Guo , Jianyi Ren , Min-Kang Hsieh , Minchen Chien , Chuanjuan Tao , Ece Erturk , Sergey Kalachikov , James J. Russo

IPC分类号： C12Q1/68 , C07H19/10 , C07H19/14 , C07H19/20 , C12Q1/6869

CPC分类号： C12Q1/6869 , C07H19/10 , C07H19/14 , C07H19/20 , C12Q1/6869 , C12Q2525/117 , C12Q2563/107

摘要： Disclosed herein, inter alia, are compounds, compositions, and methods of use thereof in the sequencing of a nucleic acid.

5.

发明申请
POLYMER TAGGED NUCLEOTIDES FOR SINGLE MOLECULE ELECTRONIC SNP ASSAY 审中-公开

公开(公告)号：US20180112257A1

公开(公告)日：2018-04-26

申请号：US15560820

申请日：2016-03-22

申请人： Jingyue Ju , Youngjin Cho , Shiv Kumar , Sergey Kalachikov , Chuanjuan Tao , Minchen Chien , James J. Russo

发明人： Jingyue Ju , Youngjin Cho , Shiv Kumar , Sergey Kalachikov , Chuanjuan Tao , Minchen Chien , James J. Russo

IPC分类号： C12Q1/6827 , C12Q1/6869 , G01N33/487

摘要： This invention provides methods of using labeled nucleotide polyphosphate analogues to detect the identity or presence of a nucleotide at certain positions in nucleic acid sequences with single molecule sensitivity using nanopore detection, nucleotides and primer-conjugated nanopore proteins for use in such methods, and processes for producing such nucleotides and primer-conjugated nanopore proteins.

6.

发明申请
DESIGN AND SYNTHESIS OF NOVEL DISULFIDE LINKER BASED NUCLEOTIDES AS REVERSIBLE TERMINATORS FOR DNA SEQUENCING BY SYNTHESIS 有权

公开(公告)号：US20220411860A1

公开(公告)日：2022-12-29

申请号：US17373295

申请日：2021-07-12

申请人： Jingyue Ju , Xiaoxu Li , Xin Chen , Zengmin Li , Shiv Kumar , Shundi Shi , Cheng Guo , Jianyi Ren , Min-Kang Hsieh , Minchen Chien , Chuanjuan Tao , Ece Erturk , Sergey Kalachikov , James J. Russo

发明人： Jingyue Ju , Xiaoxu Li , Xin Chen , Zengmin Li , Shiv Kumar , Shundi Shi , Cheng Guo , Jianyi Ren , Min-Kang Hsieh , Minchen Chien , Chuanjuan Tao , Ece Erturk , Sergey Kalachikov , James J. Russo

IPC分类号： C12Q1/6869 , C07H19/10 , C07H19/14 , C07H19/20

摘要： Disclosed herein, inter alfa, are compounds, compositions, and methods of use thereof in the sequencing of a nucleic acid.

7.

发明授权
Polymer tagged nucleotides for single molecule electronic SNP assay 有权

公开(公告)号：US10662463B2

公开(公告)日：2020-05-26

申请号：US15560820

申请日：2016-03-22

申请人： Jingyue Ju , Youngjin Cho , Shiv Kumar , Sergey Kalachikov , Chuanjuan Tao , Minchen Chien , James J. Russo

发明人： Jingyue Ju , Youngjin Cho , Shiv Kumar , Sergey Kalachikov , Chuanjuan Tao , Minchen Chien , James J. Russo

IPC分类号： C12Q1/6827 , C12Q1/6869 , G01N33/487

摘要： This invention provides methods of using labeled nucleotide polyphosphate analogues to detect the identity or presence of a nucleotide at certain positions in nucleic acid sequences with single molecule sensitivity using nanopore detection, nucleotides and primer-conjugated nanopore proteins for use in such methods, and processes for producing such nucleotides and primer-conjugated nanopore proteins.

8.

发明申请
DNA SEQUENCING BY SYNTHESIS USING MODIFIED NUCLEOTIDES AND NANOPORE DETECTION 审中-公开
标题翻译：通过使用修饰的核苷酸和纳米RNA检测合成DNA

公开(公告)号：US20130264207A1

公开(公告)日：2013-10-10

申请号：US13994431

申请日：2011-12-16

申请人： Jingyue Ju , Shiv Kumar , Zengmin Li , Chuanjuan Tao , Minchen Chien , James J. Russo , Sergey Kalachikov , Ken Shepard , Jacob Karl Rosenstein

发明人： Jingyue Ju , Shiv Kumar , Zengmin Li , Chuanjuan Tao , Minchen Chien , James J. Russo , Sergey Kalachikov , Ken Shepard , Jacob Karl Rosenstein

IPC分类号： C12Q1/68 , C07H21/00 , C07H19/10

CPC分类号： C12Q1/6869 , C07H19/10 , C07H21/00 , G01N33/48721 , C12Q2525/113 , C12Q2525/117 , C12Q2565/518 , C12Q2565/631

摘要： This disclosure is related to a method of sequencing a single-stranded DNA using deoxynucleotide polyphosphate analogues and translocation of tags from incorporated deoxynucleotide polyphosphate analogues through a nanopore.

摘要翻译： 本公开涉及使用脱氧核苷酸多磷酸酯类似物测序单链DNA并通过纳米孔从掺入的脱氧核苷酸多磷酸酯类似物转运标签的方法。

9.

发明授权
Method for detecting multiple predetermined compounds in a sample 有权

公开(公告)号：US10732183B2

公开(公告)日：2020-08-04

申请号：US14776461

申请日：2014-03-14

申请人： Jingyue Ju , Shiv Kumar , Chuanjuan Tao , Sergey Kalachikov , James J. Russo

发明人： Jingyue Ju , Shiv Kumar , Chuanjuan Tao , Sergey Kalachikov , James J. Russo

IPC分类号： C12Q1/68 , C07H21/00 , G01N33/68 , G01N33/487 , C08G65/48

摘要： This invention provides methods for detecting the presence of a plurality of predetermined compounds in a sample using a plurality of tag moieties and at least one nanopore. This invention also provides methods for determining the quantity of each of a plurality of predetermined compounds in a sample using a plurality of tag moieties and at least one nanopore. This invention further provides methods for detecting interaction of at least two predetermined compounds using at least one tag moiety and at least one nanopore.