公开(公告)号：US20240294891A1

公开(公告)日：2024-09-05

申请号：US18571437

申请日：2022-06-20

Applicant: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION

Inventor： Kyoung Heon KIM ,  So Ra YU ,  Ye Rin JIN ,  Eun Ju YUN

IPC: C12N9/38 ,  C12N15/81 ,  C12P19/02 ,  C12P19/14

CPC classification number: C12N9/2468 ,  C12N15/81 ,  C12P19/02 ,  C12P19/14 ,  C12Y302/01081

Abstract: The present invention relates to a strain that produces neoagarooligosaccharides from agarose, which is a representative polysaccharide constituting red algae, using Saccharomyces boulardii, which is a probiotic yeast, a production method thereof, and a use thereof. The present invention aims to achieve synbiotics through the production of prebiotic substances using probiotic strains and can be used as an intestinal microbial factory.

公开(公告)号：US20240132922A1

公开(公告)日：2024-04-25

申请号：US18278976

申请日：2022-02-25

Applicant: Korea University Research and Business Foundation

Inventor： Kyoung Heon KIM ,  Dong Hyun KIM ,  Jae Kyun KIM ,  Dong Oh HAN

IPC: C12P7/42 ,  C07C67/297

CPC classification number: C12P7/42 ,  C07C67/297

Abstract: The present invention relates to a chemical and biological integrated degradation process for PET, for recycling PET, and, more specifically, the present invention provides a PET upcycling technique for producing a high-value product via a chemical pretreatment process of PET, a TPA and EG production process using an enzyme, and a process for converting TPA and EG to PCA and GLA, respectively.

公开(公告)号：US20220033790A1

公开(公告)日：2022-02-03

申请号：US17299194

申请日：2019-12-04

Applicant: Korea University Research and Business Foundation

Inventor： Kyoung Heon KIM ,  Thirumalaisamy BABU ,  Do Hyoung KIM ,  Jong Hwa LEE ,  Jung Moo LEE ,  Ho Chang LEE ,  Sung Ho OH ,  Su Han KIM ,  Chang Seok HYUN

IPC: C12N9/20 ,  C07K14/40 ,  C12P7/44

Abstract: The present invention relates to a Candida tropicalis cell line, which comprises a mutant gene, having improved tolerance for cytotoxicity of stromal cells, and a method for producing dicarboxylic acid using the Candida tropicalis cell line. The Candida tropicalis cell line for producing dicarboxylic acid developed according to the present invention has improved tolerance for existing stromal toxicity as well as significantly improved efficiency for producing dicarboxylic acid compared to existing cell lines, thus can be used in biological production of dicarboxylic acid and is expected to have high industrial utility.

公开(公告)号：US20210040522A1

公开(公告)日：2021-02-11

申请号：US16979568

申请日：2019-03-08

Applicant: Korea University Research and Business Foundation

Inventor： Kyoung Heon KIM ,  Dong-Hyun KIM

IPC: C12P19/02 ,  C12P19/04 ,  C12P19/14 ,  C12P19/18 ,  C12N9/42

Abstract: The present invention relates to a novel beta-glucosidase for producing glucose and a laminarioligosaccharide from seaweed. More particularly, the present invention may produce glucose from a beta-glucosidase exhibiting transglycosylase activity while showing exo-type glucanase activity against beta-glucan, as well as produce a laminarioligosaccharide by exhibiting transglycosylase activity against laminarin under different reaction conditions.

公开(公告)号：US20220137012A1

公开(公告)日：2022-05-05

申请号：US17432734

申请日：2020-02-21

Applicant: Korea University Research and Business Foundation

Inventor： Kyoung Heon KIM ,  Hoon Suk CHA ,  Joong Kyong AHN ,  Jung Yeon KIM

IPC: G01N30/72 ,  G01N30/86 ,  G01N30/14

Abstract: The present invention relates to a method for metabolite sampling and analysis for reproducibly sampling as many metabolites as possible in a urine sample without changing to metabolites. The method has effects of presenting a biomarker detection method according to the sex or the like, by establishing optimal conditions for metabolite sampling in urine samples and presenting a metabolite comparison analysis method between different groups on the basis of the optimal conditions.

公开(公告)号：US20210317492A1

公开(公告)日：2021-10-14

申请号：US17273886

申请日：2019-09-05

Applicant: Korea University Research and Business Foundation

Inventor： Kyoung Heon KIM ,  Dong Hyun KIM ,  Eun-Ju YUN

IPC: C12P19/02 ,  C07H1/00 ,  C12P17/04 ,  C07H17/04

Abstract: The present invention relates to a method for chemical production of 3,6-anhydro-L-galactitol (L-AHGoI), which is a novel sugar alcohol, and agarobititol (ABol), which is a disaccharide having the same agarobititol as a reductant end thereof, from sea algae.

公开(公告)号：US20210214705A1

公开(公告)日：2021-07-15

申请号：US17054969

申请日：2019-05-15

Applicant: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS ,  KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION

Inventor： Yong-Su JIN ,  Jingjing LIU ,  Sora YU ,  Eun Ju YUN ,  Suryang KWAK ,  Kyoung Heon KIM ,  Jaewon LEE

IPC: C12N9/88 ,  C12N9/04 ,  C07K14/395 ,  C12N9/10 ,  C12P19/18 ,  C12N15/81

Abstract: Compositions and methods are provided for producing 2′fucosyliaciose and L-fucose from recombinant microorganisms.

公开(公告)号：US20220244273A1

公开(公告)日：2022-08-04

申请号：US17619290

申请日：2020-06-12

Applicant: Korea University Research and Business Foundation

Inventor： Kyoung Heon KIM ,  Hoon Suk CHA ,  Joong Kyong AHN ,  Jung Yeon KIM ,  Yu Eun CHEONG

IPC: G01N33/68 ,  G01N30/88 ,  G01N30/72

Abstract: The present invention relates to a method for diagnosing the severity of rheumatoid arthritis using metabolite analysis. The present invention provides a biomarker which is for classifying the severity of rheumatoid arthritis in patients suffering from same through the analysis of joint capsule fluid metabolites, and can be applied to a kit for more specifically classifying the severity of rheumatoid arthritis in patients.

公开(公告)号：US20220177668A1

公开(公告)日：2022-06-09

申请号：US17602574

申请日：2020-04-08

Applicant: Korea University Research and Business Foundation ,  EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION ,  KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY

Inventor： Kyoung Heon KIM ,  Jeong Chan JOO ,  Hee Taek KIM ,  Si Jae PARK ,  Hyun Gil CHA ,  Bong Keun SONG ,  Jae Kyun KIM

IPC: C08J11/14 ,  C08G63/183 ,  C12P7/42 ,  C12P7/44 ,  C12P7/22

Abstract: The present invention pertains to a method for producing high value-added compounds from polyethylene terephthalate. More specifically, the present invention demonstrates that a monomeric terephthalic acid obtained from the chemical hydrolysis of polyethylene terephthalate can be converted to high value-added aromatic compounds and aromatic-derived compounds, and ethylene glycol, which is another monomer of polyethylene terephthalate, can be converted to glycolic acid, which is a cosmetic material. The present invention is characterized by recycling polyethylene terephthalate waste into high value-added compounds.

公开(公告)号：US20200165646A1

公开(公告)日：2020-05-28

申请号：US16084144

申请日：2017-03-31

Applicant: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION

Inventor： Kyoung Heon KIM ,  ln-Geol CHOI ,  Sora YU ,  Eun-Ju YUN ,  Kyung-mun CHO

IPC: C12P19/02

Abstract: The present invention relates to a novel method for purifying 3,6-anhydro-L-galactose by using microorganisms and provides an effect of improving the production yield of 3,6-anhydro-L-galactose by using microorganisms during purification after enzymatic hydrolysis of agarose or agar.