公开(公告)号：US11590499B2

公开(公告)日：2023-02-28

申请号：US16994289

申请日：2020-08-14

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Jon Hoshizaki ,  Patrick Leung ,  David Marran ,  Mark Reed

IPC: B01L3/00

Abstract: An apparatus includes a fluidic coupler including an opening. A first port is in fluid communication with the opening and is to interface with an inlet of a flow cell of a sensor device. A second port is to interface with an outlet of the flow cell of the sensor device. A third port is in fluidic communication with the second port. The apparatus further includes a mechanical assembly moveable between a first position and a second position. The fluidic coupler is secured to the flow cell of the sensor device in the first position. The fluidic coupler is disengaged from the flow cell of the sensor device in the second position.

公开(公告)号：US20240390901A1

公开(公告)日：2024-11-28

申请号：US18792286

申请日：2024-08-01

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Jon Hoshizaki ,  Mark Reed ,  David Marran ,  Patrick Leung

IPC: B01L3/00 ,  A61J1/20

Abstract: A method of applying a fluid composition to a flow cell of a sensor device includes inserting the sensor device into a holder; pipetting an aliquot of the fluid composition into a pipette tip; and applying the aliquot of the fluid composition to an opening of a fluidic connector engaged with the flow cell of the sensor device. The fluidic connector includes a body; and a plurality of fluidics interfaces formed in the body, each fluidic interface of the plurality of fluidics interfaces includes an opening, a first port in fluid communication with the opening, a second port, and a third port in fluidic communication with the second port.

公开(公告)号：US10107828B2

公开(公告)日：2018-10-23

申请号：US15259191

申请日：2016-09-08

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Jon Hoshizaki

IPC: G01N35/00 ,  B01L3/00 ,  B01L9/00 ,  G01N35/10

Abstract: A clamp device includes a frame; a carriage slidably engaged with the frame and including a receptacle to receive a cartridge including fluidics ports and electronic contacts, the carriage slidable between an open position and a closed position; a fluidics interface to engage the fluidics ports of the cartridge when the carriage is in a closed position; an electronic interface to engage the electronic contacts of the cartridge when the carriage is in the closed position; a driver to draw the fluidics interface and the electronic interface together, the cartridge secured between the electronic interface and the fluidics interface; and a sensor system to detect the presence of the cartridge in the receptacle and configured to prevent the driver from drawing the fluidics interface and electronic interface together when the cartridge is absent.

公开(公告)号：US12076722B2

公开(公告)日：2024-09-03

申请号：US18107887

申请日：2023-02-09

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Jon Hoshizaki ,  Patrick Leung ,  David Marran ,  Mark Reed

IPC: B01L3/00 ,  A61J1/20 ,  B01F23/00 ,  B01F23/41 ,  B01F101/23 ,  B23Q17/24 ,  C12M1/34 ,  C12Q1/04 ,  C12Q1/18 ,  C12Q1/686 ,  G01N21/3577 ,  G01N21/359 ,  G01N21/39 ,  G01N21/45 ,  G01N21/64 ,  G01N30/12 ,  G01N30/68 ,  G01N30/70 ,  G01N30/72 ,  G01N30/88 ,  G01N33/00 ,  G01N33/18 ,  G01N33/50 ,  G01N33/68

CPC classification number: B01L3/502738 ,  A61J1/2058 ,  B01L3/502715 ,  B01L3/50273 ,  B01L2300/0816

Abstract: A fluidic coupler to engage a plurality of flow cells of a sensor device includes a body and a plurality of fluidics interfaces formed in the body. Each fluidic interface of the plurality of fluidics interfaces includes an opening, a first port in fluid communication with the opening, a second port, and a third port in fluidic communication with the second port.

公开(公告)号：US20170065981A1

公开(公告)日：2017-03-09

申请号：US15259191

申请日：2016-09-08

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Jon Hoshizaki

IPC: B01L9/00 ,  G01N35/00 ,  B01L3/00

CPC classification number: G01N35/00623 ,  B01L3/502715 ,  B01L9/527 ,  B01L2200/025 ,  B01L2200/027 ,  B01L2200/04 ,  B01L2200/141 ,  B01L2200/143 ,  B01L2300/0627 ,  B01L2300/18 ,  G01N35/00029 ,  G01N35/1095 ,  G01N2035/00158

Abstract: A clamp device includes a frame; a carriage slidably engaged with the frame and including a receptacle to receive a cartridge including fluidics ports and electronic contacts, the carriage slidable between an open position and a closed position; a fluidics interface to engage the fluidics ports of the cartridge when the carriage is in a closed position; an electronic interface to engage the electronic contacts of the cartridge when the carriage is in the closed position; a driver to draw the fluidics interface and the electronic interface together, the cartridge secured between the electronic interface and the fluidics interface; and a sensor system to detect the presence of the cartridge in the receptacle and configured to prevent the driver from drawing the fluidics interface and electronic interface together when the cartridge is absent.

Abstract translation: 夹具装置包括框架; 滑架与所述框架接合并且包括用于容纳包括流体端口和电子触头的盒的容器的滑架，所述滑架可在打开位置和关闭位置之间滑动; 当滑架处于关闭位置时，流体接口接合盒的流体端口; 电子接口，当滑架处于关闭位置时接合盒的电子触点; 驱动器将流体界面和电子接口拉在一起，盒被固定在电子界面和流体界面之间; 以及传感器系统，用于检测存储盒在存储器中的存在并被配置为防止当存储盒不存在时驱动程序将流体接口和电子接口拉在一起。