中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

9 records (took 0.017 seconds)

    MULTIPLEX Y-STR ANALYSIS
    6.
    发明申请
    MULTIPLEX Y-STR ANALYSIS 审中-公开
    MULTIPLEX Y-STR分析

    公开(公告)号：US20160053311A1

    公开(公告)日：2016-02-25

    申请号：US14727442

    申请日：2015-06-01

    Applicant: LIFE TECHNOLOGIES CORPORATION

    Inventor： Christina BORMANN CHUNG ,  Julio Mulero ,  Lori Hennessy

    IPC: C12Q1/68

    CPC classification number: C12Q1/6858 ,  C12Q1/686 ,  C12Q1/6879 ,  C12Q1/6888 ,  C12Q2600/156 ,  C12Q2600/16 ,  C12Q2525/101 ,  C12Q2525/204 ,  C12Q2537/143

    Abstract: Novel Y-STR multiplex analysis designs, primer design, allelic ladders, methods of use and kits are disclosed, including the use of primer sets designed to provide amplicons for at least 11 Y-STR loci having a base pair size of less than about 220 bp, as well as the use of primer sets designed to provide amplicons for at least 22 Y-STR loci including at least 5 rapidly mutating loci.

    Abstract translation: 公开了新颖的Y-STR多重分析设计，引物设计，等位基因梯度，使用方法和试剂盒，包括使用设计用于提供具有小于约220的碱基对大小的至少11个Y-STR基因座的扩增子的引物组 bp，以及设计用于为包含至少5个快速突变基因座的至少22个Y-STR基因座提供扩增子的引物组的使用。

    Mesylate based master mix
    8.
    发明授权
    Mesylate based master mix 有权

    公开(公告)号：US11293059B2

    公开(公告)日：2022-04-05

    申请号：US16623975

    申请日：2018-06-20

    Applicant: LIFE TECHNOLOGIES CORPORATION

    Inventor： Chang Zhong ,  Julio Mulero ,  Steven Menchen

    IPC: C12Q1/686 ,  C12Q1/6848

    Abstract: Disclosed herein are mesylate containing compositions, methods of use of such compositions and kits of components encompassing such compositions for improving the amplification of nucleic acids, especially in the presence of enzymatic inhibitors. These find particular use in forensic and environmental analyses. The instant disclosure provides new compositions, methods and kits of components for overcoming PCR inhibition. In some embodiments disclosed herein is a PCR master mix, the PCR master mix encompassing a mesylate.

    SE33 MUTATIONS IMPACTING GENOTYPE CONCORDANCE
    9.
    发明申请
    SE33 MUTATIONS IMPACTING GENOTYPE CONCORDANCE 审中-公开
    SE33突变影响基因型的意义

    公开(公告)号：US20160010146A1

    公开(公告)日：2016-01-14

    申请号：US14809418

    申请日：2015-07-27

    Applicant: LIFE TECHNOLOGIES CORPORATION

    Inventor： Robert GREEN ,  Dennis Wang ,  Julio Mulero ,  Robert Lagace

    IPC: C12Q1/68

    CPC classification number: C12Q1/6827 ,  C12Q1/686 ,  C12Q1/6888 ,  C12Q2537/143 ,  C12Q2600/156

    Abstract: Disclosed are primer set compositions, methods and kits for human identification using the highly complex sequence locus, SE33 (ACTBP2) in single and multiplex PCR reactions. Additionally, disclosed are three newly discovered single nucleotide polymorphisms (SNPs) within the SE33 locus that can cause discordance seen as mobility shift or allelic dropout. Also disclosed are kits useful in human identification.

    Abstract translation: 公开了使用高度复杂的序列位点SE33（ACTBP2）在单次和多重PCR反应中进行人类鉴定的引物组合物，方法和试剂盒。 另外，所公开的是在SE33基因座内的三种新发现的单核苷酸多态性（SNP），其可以导致视为移动性偏移或等位基因缺失的不一致。 还公开了可用于人类鉴定的试剂盒。

Patent Agency Ranking