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    Systems and methods for restoring function of diseased bowel
    4.
    发明申请
    Systems and methods for restoring function of diseased bowel 审中-公开
    恢复肠道功能的系统和方法

    公开(公告)号：US20080039878A1

    公开(公告)日：2008-02-14

    申请号：US11825464

    申请日：2007-07-06

    申请人： Michael Williams ,  Daniel Fifer ,  William Athas ,  Richard Stack ,  Aurora Pryor

    发明人： Michael Williams ,  Daniel Fifer ,  William Athas ,  Richard Stack ,  Aurora Pryor

    IPC分类号： A61F2/04

    CPC分类号： A61F2/04 ,  A61B17/1114 ,  A61B2017/1135

    摘要： In a first embodiment of a system for treating diseased bowel, a pair of incisions are formed on opposite ends of a diseased section of bowel. A tubular bypass implant is positioned in the bowel such that its ends are anchored within the bowel and such that an intermediate section of the implant is positioned external to the bowel such that bowel contents flow through the implant and thus around the diseased bowel section. In a second embodiment, the diseased section of bowel is removed and a system is implanted for joining limbs of the resected bowel together to form an anastomosis. In the preferred anastomosis system, the limbs of the resected bowel are positioned between a tubular sleeve extending through the bowel and a tubular cuff positioned around the bowel.

    摘要翻译： 在用于治疗患病肠的系统的第一实施例中，在患病部分的肠的相对端形成一对切口。 管状旁路植入物定位在肠中，使得其端部锚定在肠内，并且使得植入物的中间部分位于肠的外部，使得肠内容物流过植入物并因此流过患病肠段。 在第二实施例中，去除肠部疾病部位并植入用于将切除的肠的肢体连接在一起以形成吻合的系统。 在优选的吻合系统中，切除的肠的四肢位于延伸穿过肠的管状套管和围绕肠周围的管状袖带之间。

    Intravascular electrophysiological system and methods
    6.
    发明申请
    Intravascular electrophysiological system and methods 有权
    血管内电生理系统和方法

    公开(公告)号：US20080077219A1

    公开(公告)日：2008-03-27

    申请号：US11980006

    申请日：2007-10-30

    申请人： Michael Williams ,  Terrance Ransbury ,  Richard Glenn ,  Daniel Fifer ,  Kevin Holbrook

    发明人： Michael Williams ,  Terrance Ransbury ,  Richard Glenn ,  Daniel Fifer ,  Kevin Holbrook

    IPC分类号： A61N1/05

    CPC分类号： A61N1/057 ,  A61N1/37205 ,  A61N1/375

    摘要： The present application describes an intravascular implantable pacing and/or defibrillation system. The described system includes a pulse generator that is implantable within a blood vessel and proportioned to blood flow through the blood vessel, and at least one electrode attachable to the pulse generator. During implantation, the pulse generator is introduced into a patient's vasculature, advanced to a desired vessel and anchored in place within the vessel. The electrode or electrodes are placed within the heart or surrounding vessels as needed to deliver electrical pulses to the appropriate location.

    摘要翻译： 本申请描述了血管内可植入起搏和/或除颤系统。 所描述的系统包括脉冲发生器，该脉冲发生器可植入在血管内并与通过血管的血液流动成比例，以及至少一个可附着到脉冲发生器的电极。 在植入期间，将脉冲发生器引入患者的脉管系统中，前进到期望的血管并锚定在血管内的适当位置。 根据需要将电极或电极放置在心脏或周围血管内，以将电脉冲传递到适当的位置。

    Intravascular electrophysiological system and methods
    7.
    发明申请
    Intravascular electrophysiological system and methods 有权
    血管内电生理系统和方法

    公开(公告)号：US20050043765A1

    公开(公告)日：2005-02-24

    申请号：US10862113

    申请日：2004-06-04

    申请人： Michael Williams ,  Terrance Ransbury ,  Richard Glenn ,  Daniel Fifer ,  Kevin Holbrook

    发明人： Michael Williams ,  Terrance Ransbury ,  Richard Glenn ,  Daniel Fifer ,  Kevin Holbrook

    IPC分类号： A61N1/372 ,  A61N1/375 ,  A61N1/36

    CPC分类号： A61N1/057 ,  A61N1/37205 ,  A61N1/375

    摘要： The present application describes an intravascular implantable pacing and/or defibrillation system. The described system includes a pulse generator that is implantable within a blood vessel and proportioned to blood flow through the blood vessel, and at least one electrode attachable to the pulse generator. During implantation, the pulse generator is introduced into a patient's vasculature, advanced to a desired vessel and anchored in place within the vessel. The electrode or electrodes are placed within the heart or surrounding vessels as needed to deliver electrical pulses to the appropriate location.

    摘要翻译： 本申请描述了血管内可植入起搏和/或除颤系统。 所描述的系统包括脉冲发生器，该脉冲发生器可植入在血管内并与通过血管的血液流动成比例，以及至少一个可附着到脉冲发生器的电极。 在植入期间，将脉冲发生器引入患者的脉管系统中，前进到期望的血管并锚定在血管内的适当位置。 根据需要将电极或电极放置在心脏或周围血管内，以将电脉冲传递到适当的位置。

    METHODS AND SYSTEMS FOR REMOVAL OF IMPLANTABLE INTRAVASCULAR DEVICES
    8.
    发明申请
    METHODS AND SYSTEMS FOR REMOVAL OF IMPLANTABLE INTRAVASCULAR DEVICES 审中-公开
    用于移除可植入的血管内装置的方法和系统

    公开(公告)号：US20110112548A1

    公开(公告)日：2011-05-12

    申请号：US12941796

    申请日：2010-11-08

    申请人： Daniel Fifer ,  Richard Glenn ,  Jeffrey Smith ,  Geoff Orth ,  Michael Williams ,  William Sanders ,  Earl Bardsley ,  Wendy Graczyk

    发明人： Daniel Fifer ,  Richard Glenn ,  Jeffrey Smith ,  Geoff Orth ,  Michael Williams ,  William Sanders ,  Earl Bardsley ,  Wendy Graczyk

    IPC分类号： A61B19/00

    CPC分类号： A61B17/320016 ,  A61B17/29 ,  A61B2017/00358 ,  A61B2017/32006 ,  A61N1/37205 ,  A61N2001/0578

    摘要： Improved methods, systems and apparatuses for extracting devices implanted within the vasculature of a patient are provided, including a method of extracting an intravascular device anchored in a vasculature of a patient, the device including a device body and a lead coupled to the device body, the lead having a distal end including an electrode, the distal end being fixed in a heart of the patient, the method comprising forming an incision in the vasculature, disconnecting the lead from the device body, removing the distal end of the lead from the heart, withdrawing the lead from the patient, disconnecting the device body from an anchor, and withdrawing the device body from the patient via the incision.

    摘要翻译： 提供了用于提取植入患者脉管系统内的装置的改进的方法，系统和装置，包括提取锚定在患者脉管系统中的血管内装置的方法，所述装置包括装置主体和耦合到装置主体的引线， 所述引线具有包括电极的远端，所述远端固定在患者的心脏中，所述方法包括在所述脉管系统中形成切口，将所述引线与所述装置主体断开，从所述心脏移除所述引线的远端 从患者撤回引线，将装置主体与锚固件断开，并通过切口将装置主体从患者身体中取出。

    Renal blood flow augmentation for congestive heart failure treatment
    9.
    发明申请
    Renal blood flow augmentation for congestive heart failure treatment 审中-公开
    充血性心力衰竭治疗的肾血流增加

    公开(公告)号：US20070293808A1

    公开(公告)日：2007-12-20

    申请号：US11796179

    申请日：2007-04-27

    申请人： Michael Williams ,  Daniel Fifer

    发明人： Michael Williams ,  Daniel Fifer

    IPC分类号： A61M27/00

    CPC分类号： A61F2/06 ,  A61F2/2412 ,  A61F2/2421 ,  A61F2/2424 ,  A61F2/2475 ,  A61F2002/068

    摘要： Intravascular devices are delivered to the aorta percutaneously via the femoral artery. The devices are anchored within the vasculature in the region of the renal artery ostia. These embodiments function to increase the flow of blood from the aorta to the renal arteries, thus delivering a higher relative percentage of the blood flowing through the aorta to the kidneys. The elevation in blood low to the kidneys improves the natural removal of excess fluids from the body. In one embodiment, the device is a diverter element positionable upstream of the renal artery ostia. In another embodiment, the device is a flow restrictor positionable downstream of the ostia to cause an elevation is pressure upstream of the ostia.

    摘要翻译： 血管内装置通过股动脉经皮输送到主动脉。 该装置锚定在肾动脉口区域内的脉管系统内。 这些实施例用于增加从主动脉到肾动脉的血液流动，从而将流过主动脉的血液的较高相对百分比传递给肾脏。 血液低至肾脏的血压提高了身体多余液体的自然去除。 在一个实施例中，该装置是可定位在肾动脉口的上游的分流元件。 在另一个实施例中，该装置是可定位在口部下游的限流器，从而导致高度在口腔上游的压力。

    Stent with eccentric coating
    10.
    发明申请
    Stent with eccentric coating 审中-公开
    支架偏心涂层

    公开(公告)号：US20060149365A1

    公开(公告)日：2006-07-06

    申请号：US10531694

    申请日：2003-10-21

    申请人： Daniel Fifer ,  John Nolting

    发明人： Daniel Fifer ,  John Nolting

    IPC分类号： A61F2/06

    CPC分类号： A61F2/915 ,  A61F2/0077 ,  A61F2002/91541 ,  A61F2002/91558 ,  A61F2230/0054 ,  A61F2250/0036 ,  A61F2250/0067 ,  B05D1/28

    摘要： The stent (120) with an eccentric coating (130) of the present invention provides a coating having a different coating thickness on the stent outer diameter and stent inner diameter, i.e., an eccentric coating. The eccentric coating can be the primary carrier for a drug or other therapeutic agent. The eccentric coating can be thicker on the stent outer diameter to supply more drug to the vessel wall in which the coated stent is deployed and less drug to the vessel lumen. In one embodiment, a cap coating (125) can be disposed on the eccentric coating to protect the eccentric coating, control the elution rate from the eccentric coating, provide an additional drug carrier, or provide combinations thereof. The eccentric coating can be applied by spraying a coating liquid on the stent outer diameter with a fixture mandrel interior to the stent to regulate the spray to the stent inner diameter.

    摘要翻译： 具有本发明的偏心涂层（130）的支架（120）提供了在支架外径和支架内径上即具有偏心涂层的涂层厚度不同的涂层。 偏心涂层可以是药物或其他治疗剂的主要载体。 偏心涂层可以在支架外径上更厚，以向涂层支架部署的血管壁提供更多的药物，并将更少的药物提供给血管腔。 在一个实施例中，帽涂层（125）可以设置在偏心涂层上以保护偏心涂层，控制偏心涂层的洗脱速率，提供额外的药物载体，或提供其组合。 可以通过将支架外径上的涂覆液体喷涂到支架的固定心轴内部以将喷雾调节到支架内径来施加偏心涂层。