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1.发明授权Apparatus, method and operating method of apparatus for excluding non-target-region of fluorescence 有权用于排除非目标区荧光的装置的方法和操作方法公开(公告)号：US09519967B2
公开(公告)日：2016-12-13
申请号：US14312956
申请日：2014-06-24
Applicant: OLYMPUS CORPORATION
Inventor： Hiromi Shida , Yasushige Ishihara , Satoshi Takekoshi , Kei Kubo
CPC classification number: G06T7/0014 , A61B1/00009 , A61B1/043 , G02B21/16 , G02B23/2461 , G02B23/2484 , G06K9/46 , G06K2009/4666
Abstract: Fluorescence generated at a lesion is distinguished from fluorescence generated at portions other than the lesion, and thus, observation is performed by using only the fluorescence generated at the lesion. Provided is a fluorescence observation apparatus including a light radiating portion that radiates excitation light onto an examination subject; a fluorescence-distribution acquiring portion that acquires an intensity distribution of fluorescence generated at the examination subject due to irradiation with the excitation light from the light radiating portion; and a non-target-region excluding portion that, in the fluorescence-intensity distribution acquired by the fluorescence-distribution acquiring portion, excludes regions in which a spectrum in a specific wavelength band has changed due to a specific biological component whose concentration in a lesion is lower than in other portions.
Abstract translation: 在损伤处产生的荧光与病变以外的部分产生的荧光不同，因此仅使用在病变处产生的荧光进行观察。 本发明提供一种荧光观察装置，其包括将激发光照射到检查对象上的光照射部， 荧光分布获取部分，其获取由于来自所述光辐射部分的激发光的照射而在所述检查对象产生的荧光的强度分布; 以及在由荧光分布获取部获取的荧光强度分布中排除由特定生物成分在特定波长带中的光谱变化的区域的非靶区域排除部分， 低于其他部分。
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公开(公告)号：US09518924B2
公开(公告)日：2016-12-13
申请号：US14499813
申请日：2014-09-29
Applicant: OLYMPUS CORPORATION
Inventor： Kei Kubo , Yasushige Ishihara , Hiromi Shida , Satoshi Takekoshi
CPC classification number: G01N21/6456 , A61B1/00009 , A61B1/0005 , A61B1/00055 , A61B1/043 , A61B1/045 , F04C2270/041 , G01N2201/124 , G06K9/4604 , G06T7/0012 , G06T2207/30004
Abstract: The invention provides a fluoroscopy apparatus including an image-capturing device that acquires a fluorescence image of a subject; a sensitivity adjusting portion that sets a sensitivity of the image-capturing device to fluorescence on the basis of a gradation value of the fluorescence image; a notifying portion that extracts a lesion part from the fluorescence image acquired by the image-capturing device with the sensitivity set by the sensitivity adjusting portion and presents it to an operator; and a display switching portion that displays the fluorescence image on a display unit when the sensitivity in the image-capturing device is equal to or less than a predetermined threshold and that presents information showing the existence of the lesion part on the notifying portion when the sensitivity is greater than the predetermined threshold.
Abstract translation: 本发明提供一种荧光透视装置，其包括获取被检体的荧光图像的图像捕获装置; 灵敏度调整部，其基于荧光图像的灰度值，将图像拍摄装置的感光度设定为荧光; 通知部，其以由灵敏度调节部设定的灵敏度从由摄像装置获取的荧光图像中提取病变部，并将其呈现给操作者; 以及显示切换部，当所述图像拍摄装置的灵敏度为规定阈值以下时，在所述显示部显示所述荧光图像，并且当所述灵敏度为灵敏度时，在所述通知部显示所述病变部的存在信息 大于预定阈值。
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公开(公告)号：US09332909B2
公开(公告)日：2016-05-10
申请号：US13942933
申请日：2013-07-16
Applicant: OLYMPUS CORPORATION
Inventor： Kei Kubo , Yasushige Ishihara , Hiromi Shida , Satoshi Takekoshi
CPC classification number: A61B5/0071 , A61B1/00009 , A61B1/043 , A61B1/0638 , A61B1/0646
Abstract: Provided is a fluoroscopy apparatus including a fluorescence-image generating portion that generates a fluorescence image; an identifying portion that identifies a position of a high-luminance region in the fluorescence image; a storage portion that stores the position of the high-luminance region; a detecting portion that detects an amount of change in a physical quantity, which can possibly act as a cause of changes in a property of the high-luminance region, starting from a time at which the position of the high-luminance region is identified by the identifying portion; a confidence-level calculating portion that calculates a confidence level of the property of the high-luminance region based on the detected amount of change; and a display-image generating portion that generates a display image in which the display mode at the position of the high-luminance region is set in accordance with the confidence level.
Abstract translation: 本发明提供一种荧光透视设备，包括产生荧光图像的荧光图像产生部分; 识别部，其识别所述荧光图像中的高亮度区域的位置; 存储部，其存储高亮度区域的位置; 检测部分，其从高亮度区域的位置的时间开始，从高亮度区域的位置开始，检测出物理量的变化量，其可能充当高亮度区域的性质变化的原因， 识别部分; 置信度计算部，其基于检测出的变化量来计算高亮度区域的属性的置信度; 以及显示图像生成部，其生成根据置信水平设定高亮度区域的位置的显示模式的显示图像。
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公开(公告)号：US09824444B2
公开(公告)日：2017-11-21
申请号：US15293531
申请日：2016-10-14
Applicant: OLYMPUS CORPORATION
Inventor： Kei Kubo
CPC classification number: G06T7/0012 , A61B1/00009 , A61B1/043 , A61B1/0638 , A61B5/0071 , A61N5/06 , A61N5/0603 , A61N5/062 , A61N2005/0626 , A61N2005/063 , A61N2005/067 , G02B23/24 , G06T7/0016 , G06T2207/10016 , G06T2207/10064 , G06T2207/10068 , G06T2207/10152 , G06T2207/30096
Abstract: An image processing apparatus includes an input section, a specification section, an extraction section, and a calculation section. The input section receives fluorescence image information obtained by picking up an image of fluorescence based on application of excitation light to a subject provided with a fluorescent substance with a specific effect on a living tissue and therapeutic light position image information including an application position of therapeutic light. The specification section specifies an application region of the therapeutic light. The extraction section extracts a luminance value corresponding to the application region of the therapeutic light and a luminance value corresponding to a region other than the application region of the therapeutic light. The calculation section calculates and outputs a ratio of the extracted luminance value corresponding to the application region to the luminance value corresponding to the region other than the application region.
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公开(公告)号：US11723513B2
公开(公告)日：2023-08-15
申请号：US17009055
申请日：2020-09-01
Applicant: OLYMPUS CORPORATION
Inventor： Kei Kubo , Makoto Igarashi
CPC classification number: A61B1/000094 , A61B1/00045 , A61B1/044 , A61B1/046 , A61B1/0638
Abstract: An endoscope system includes a light source apparatus to generate an illumination light including a first light in a red to near infrared region, a second light in a green region, and a third light in a blue region, an image pickup device to pick up an image of an object and output an image pickup signal, and a processor to generate a first to third color components corresponding to the first to third lights based on an image generated according to the image pickup signal. The processor generates two of three color components that are blue, green, and red included in an observation image by using a second color component, and generates one remaining color component by using a first color component, and generates respective color components of red, green, and blue included in a white light observation image by using the first to third color components.
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Patent Agency Ranking
公开(公告)号：US10893810B2
公开(公告)日：2021-01-19
申请号：US16263385
申请日：2019-01-31
Applicant: OLYMPUS CORPORATION
Inventor： Kei Kubo
IPC: A61B5/02 , G06T7/00 , G06T7/11 , H04N5/225 , A61B5/1459 , A61B1/06 , A61B1/045 , A61B1/05 , A61B1/00 , A61B5/00 , G02B23/24 , A61B1/04 , A61B1/055
Abstract: A video processor includes: a region extracting circuit that receives an input of a first image signal obtained by forming an image of a subject irradiated with first narrow band light including a wavelength that is minimally absorbed by blood within a green wavelength band, the image of the subject including a bleeding point, and extract a blood pool region having a blood concentration that is lower than a blood concentration of the bleeding point in a region representing the blood in the first image signal; and an image generating circuit that raises a luminance value of the blood pool region in either the first image signal or a second image signal obtained by forming an image of the subject irradiated with second narrow band light whose wavelength is shorter and which is more absorbed by the blood than the first narrow band light.
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公开(公告)号：US12295544B2
公开(公告)日：2025-05-13
申请号：US18213043
申请日：2023-06-22
Applicant: OLYMPUS CORPORATION
Inventor： Kei Kubo , Makoto Igarashi
Abstract: An endoscope system includes a light source apparatus to generate an illumination light including a first light in a red to near infrared region, a second light in a green region, and a third light in a blue region, an image pickup device to pick up an image of an object and output an image pickup signal, and a processor to generate a first to third color components corresponding to the first to third lights based on an image generated according to the image pickup signal. The processor generates two of three color components that are blue, green, and red included in an observation image by using a second color component, and generates one remaining color component by using a first color component, and generates respective color components of red, green, and blue included in a white light observation image by using the first to third color components.
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公开(公告)号：US09839359B2
公开(公告)日：2017-12-12
申请号：US15046860
申请日：2016-02-18
Applicant: OLYMPUS CORPORATION
Inventor： Kei Kubo , Yasushige Ishihara
IPC: A61B5/00 , H04N7/18 , A61B1/00 , A61B1/04 , A61B1/045 , G06T5/50 , G06T5/00 , G06T19/00 , G06T19/20 , A61B1/06
CPC classification number: A61B5/0071 , A61B1/00009 , A61B1/0005 , A61B1/043 , A61B1/045 , A61B1/0638 , A61B1/0646 , G06T5/008 , G06T5/50 , G06T19/006 , G06T19/20 , G06T2207/10064 , G06T2207/10068 , G06T2207/20212
Abstract: A fluorescence observation apparatus including a light source that radiates illumination light and excitation light; a return-light-image generating portion and a fluorescence-image generating portion that generate a return-light image and a fluorescence image, respectively; a fluorescence detecting portion that detects a fluorescence region in the fluorescence image; a return-light-image adjusting portion that adjusts gradation values of the return-light image; a superimposed-image generating portion that generates a superimposed image by using the return-light image, in which the gradation values have been adjusted, and the fluorescence image; and a coefficient setting portion that sets, in the case in which the fluorescence region is detected, a degree-of-reduction of the gradation values, so that the gradation values of the return-light image are decreased as compared with the case in which the fluorescence region is not detected.
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公开(公告)号：US09588046B2
公开(公告)日：2017-03-07
申请号：US14198671
申请日：2014-03-06
Applicant: OLYMPUS CORPORATION , OLYMPUS MEDICAL SYSTEMS CORP.
Inventor： Yasushige Ishihara , Hiromi Shida , Kei Kubo , Satoshi Takekoshi
CPC classification number: G01N21/64 , A61B1/00009 , A61B1/0005 , A61B1/043 , G01N21/6456 , G06T5/50 , G06T2207/20216
Abstract: Provided is a fluorescence observation apparatus including: a fluorescence image acquisition section and a reference image acquisition section that acquire a fluorescence image and a reference image of a subject, respectively; a division image generation section that generates a division image by dividing an image based on the fluorescence image by an image based on the reference image; a display section that displays a corrected fluorescence image based on the division image; a correction processing section that applies correction processing to at least one of the reference image and the fluorescence image and/or to the division image prior to the generation of the division image or prior to the display of the corrected fluorescence image; an observation condition determination section that determines observation conditions of the subject; and a correction condition setting section that sets parameters regarding the correction processing according to the observation conditions.
Abstract translation: 本发明提供一种荧光观察装置，包括：荧光图像获取部和参考图像获取部，分别获取被检体的荧光图像和参照图像; 分割图像生成部，其通过基于所述参照图像将基于所述荧光图像的图像分割为图像来生成分割图像; 显示部，其基于所述分割图像显示校正的荧光图像; 校正处理部，其在所述分割图像的生成之前或所述校正后的荧光图像的显示之前，对所述参考图像和所述荧光图像和/或所述分割图像中的至少一个进行校正处理; 观察条件确定部，其确定被检体的观察条件; 以及校正条件设定部，其根据观察条件设定关于校正处理的参数。
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公开(公告)号：US09392942B2
公开(公告)日：2016-07-19
申请号：US13952954
申请日：2013-07-29
Applicant: OLYMPUS CORPORATION
Inventor： Hiromi Shida , Yasushige Ishihara , Satoshi Takekoshi , Kei Kubo
CPC classification number: A61B5/0033 , A61B1/00009 , A61B1/0005 , A61B1/00055 , A61B1/043 , G06T5/50 , G06T7/0014 , G06T2207/10121 , G06T2207/30088
Abstract: Provided is a fluoroscopy apparatus including a light source that irradiates an observation target with reference light and excitation light; a fluorescence-image generating unit that captures fluorescence emitted from the observation target X irradiated with the excitation light to generate a fluorescence image; a reference-image generating unit that captures return light returning from the observation target irradiated with the reference light to generate a reference image; an image-combining unit that superimposes the fluorescence image on the reference image to generate a combined image; a determining unit that determines whether there is a position with a luminance at or below a predetermined threshold in the reference image; and a notifying unit that, if the determining unit determines that there is a position with a luminance at or below the predetermined threshold, provides notification thereof.
Abstract translation: 本发明提供一种荧光透视设备，包括：用参考光和激发光照射观察目标的光源; 荧光图像生成单元，其捕获从所述观察对象物X发射的荧光，所述荧光被激发光照射，以产生荧光图像; 参考图像生成单元，其捕获从所述观察对象返回的照射了所述基准光的返回光，生成参照图像; 图像合成单元，其将所述荧光图像叠加在所述参考图像上以生成组合图像; 确定单元，确定参考图像中是否存在亮度在预定阈值以下的位置; 以及通知单元，如果所述确定单元确定存在具有或低于所述预定阈值的亮度的位置，则提供通知。
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