公开(公告)号：US06519032B1

公开(公告)日：2003-02-11

申请号：US09689553

申请日：2000-10-11

Applicant: Sigrid C. Kuebler ,  James Bennett

Inventor： Sigrid C. Kuebler ,  James Bennett

IPC: G01N2100

CPC classification number: B01D15/08 ,  B01D15/26 ,  B01D15/265 ,  B01D15/325 ,  B01D15/34 ,  B01J19/0046 ,  B01J19/26 ,  B01J2219/00274 ,  B01J2219/00315 ,  B01J2219/00585 ,  B01J2219/00587 ,  B01J2219/00707 ,  B01J2219/00722 ,  C40B40/14 ,  C40B60/14 ,  G01N15/0205 ,  G01N21/253 ,  G01N21/51 ,  G01N21/532 ,  G01N30/02 ,  G01N30/16 ,  G01N30/24 ,  G01N30/30 ,  G01N30/461 ,  G01N30/466 ,  G01N30/54 ,  G01N30/60 ,  G01N30/6052 ,  G01N30/88 ,  G01N33/44 ,  G01N33/442 ,  G01N35/085 ,  G01N35/1097 ,  G01N2015/0288 ,  G01N2015/0294 ,  G01N2030/324 ,  G01N2030/625

Abstract: Methods, systems and devices are described for rapid characterization and screening of liquid samples to determine properties (e.g., particle size, particle size distribution, molar mass and/or molar mass distribution) thereof with static light scattering and/or dynamic light scattering. The liquid samples can be solutions, emulsions, suspensions or dispersions. One method, includes providing a vessel containing a liquid sample having an exposed surface that defines a gas-liquid sample interface, and analyzing the sample by light scattering methods that include transmitting light through the gas-liquid sample interface into the sample, and detecting light scattered from the sample or from a component thereof. Additional methods are directed to characterizing a plurality of liquid samples or components thereof. The methods, systems, and devices have applications in high-throughput screening, and particularly, in combinatorial materials research and in industrial process control.

Abstract translation: 描述了用于快速表征和筛选液体样品以确定静态光散射和/或动态光散射的性质（例如，粒度，粒度分布，摩尔质量和/或摩尔质量分布）的方法，系统和装置。 液体样品可以是溶液，乳液，悬浮液或分散体。 一种方法包括提供容器，该容器含有具有限定气 - 液样品界面的暴露表面的液体样品，并通过光散射方法分析样品，所述光散射方法包括将透过气 - 液样品界面的光透射到样品中，以及检测光 从样品或其组分散射。 额外的方法涉及表征多个液体样品或其组分。 方法，系统和设备在高通量筛选中具有应用，特别是在组合材料研究和工业过程控制中。

公开(公告)号：US06819420B2

公开(公告)日：2004-11-16

申请号：US10341198

申请日：2003-01-13

Applicant: Sigrid C. Kuebler ,  James Bennett

Inventor： Sigrid C. Kuebler ,  James Bennett

IPC: G01N2100

CPC classification number: B01D15/08 ,  B01D15/26 ,  B01D15/265 ,  B01D15/325 ,  B01D15/34 ,  B01J19/0046 ,  B01J19/26 ,  B01J2219/00274 ,  B01J2219/00315 ,  B01J2219/00585 ,  B01J2219/00587 ,  B01J2219/00707 ,  B01J2219/00722 ,  C40B40/14 ,  C40B60/14 ,  G01N15/0205 ,  G01N21/253 ,  G01N21/51 ,  G01N21/532 ,  G01N30/02 ,  G01N30/16 ,  G01N30/24 ,  G01N30/30 ,  G01N30/461 ,  G01N30/466 ,  G01N30/54 ,  G01N30/60 ,  G01N30/6052 ,  G01N30/88 ,  G01N33/44 ,  G01N33/442 ,  G01N35/085 ,  G01N35/1097 ,  G01N2015/0288 ,  G01N2015/0294 ,  G01N2030/324 ,  G01N2030/625

Abstract: Methods, systems and devices are described for rapid characterization and screening of liquid samples to determine properties (e.g., particle size, particle size distribution, molar mass and/or molar mass distribution) thereof with static light scattering and/or dynamic light scattering. The liquid samples can be solutions, emulsions, suspensions or dispersions. One method, includes providing a vessel containing a liquid sample having an exposed surface that defines a gas-liquid sample interface, and analyzing the sample by light scattering methods that include transmitting light through the gas-liquid sample interface into the sample, and detecting light scattered from the sample or from a component thereof. Additional methods are directed to characterizing a plurality of liquid samples or components thereof. The methods, systems, and devices have applications in high-throughput screening, and particularly, in combinatorial materials research and in industrial process control.

Abstract translation: 描述了用于快速表征和筛选液体样品以确定静态光散射和/或动态光散射的性质（例如，粒度，粒度分布，摩尔质量和/或摩尔质量分布）的方法，系统和装置。 液体样品可以是溶液，乳液，悬浮液或分散体。 一种方法包括提供容器，该容器含有具有限定气 - 液样品界面的暴露表面的液体样品，并且通过光散射方法分析样品，所述光散射方法包括将透过气 - 液样品界面的光透射到样品中，以及检测光 从样品或其组分散射。 额外的方法涉及表征多个液体样品或其组分。 方法，系统和设备在高通量筛选中具有应用，特别是在组合材料研究和工业过程控制中。

公开(公告)号：US06577392B1

公开(公告)日：2003-06-10

申请号：US09728374

申请日：2000-11-28

Applicant: Ralph B. Nielsen ,  Sigrid C. Kuebler ,  Thomas S. Lee ,  Adam Safir ,  Miroslav Petro

Inventor： Ralph B. Nielsen ,  Sigrid C. Kuebler ,  Thomas S. Lee ,  Adam Safir ,  Miroslav Petro

IPC: G01N2100

CPC classification number: B01D15/08 ,  B01D15/14 ,  B01D15/1871 ,  B01D15/1885 ,  B01J19/0046 ,  B01J19/26 ,  B01J2219/00274 ,  B01J2219/00585 ,  B01J2219/00587 ,  B01J2219/00707 ,  B01J2219/00722 ,  C40B40/14 ,  G01N15/0205 ,  G01N30/02 ,  G01N30/16 ,  G01N30/24 ,  G01N30/30 ,  G01N30/461 ,  G01N30/466 ,  G01N30/54 ,  G01N30/60 ,  G01N30/6052 ,  G01N30/88 ,  G01N33/44 ,  G01N33/442 ,  G01N35/085 ,  G01N35/1097 ,  G01N2015/0288 ,  G01N2015/0294 ,  G01N2030/324 ,  G01N2030/625 ,  B01D15/34

Abstract: Rapid characterization and screening of polymer samples to determine average molecular weight, molecular weight distribution and other properties is disclosed. Rapid flow characterization systems and methods, including liquid chromatography and flow-injection analysis systems and methods are preferably employed. High throughput, automated sampling systems and methods, high-temperature characterization systems and methods, and rapid, indirect calibration compositions and methods are also disclosed. The described methods, systems, and devices have primary applications in combinatorial polymer research and in industrial process control.

Abstract translation: 公开了聚合物样品的快速表征和筛选以确定平均分子量，分子量分布和其它性质。 优选采用快速流动表征系统和方法，包括液相色谱和流动注射分析系统和方法。 还公开了高通量，自动采样系统和方法，高温表征系统和方法以及快速，间接校准组合物和方法。 所描述的方法，系统和装置在组合聚合物研究和工业过程控制中具有主要应用。