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43 条记录 (耗时 0.038 秒)

    Nucleic acid encoding a polypeptide with the biological activity of a serine hydroxymethyltransferase
    6.
    发明授权
    Nucleic acid encoding a polypeptide with the biological activity of a serine hydroxymethyltransferase 失效
    编码具有丝氨酸羟甲基转移酶生物活性的多肽的核酸

    公开(公告)号：US07662603B2

    公开(公告)日：2010-02-16

    申请号：US11949874

    申请日：2007-12-04

    申请人： Uwe Sonnewald ,  Frederik Boernke ,  Kirsten Deist ,  Marc Stitt Nigel ,  Wolfgang Lein ,  Thomas Ehrhardt ,  Andreas Reindl ,  Ralf-Michael Schmidt ,  Annette Freund

    发明人： Uwe Sonnewald ,  Frederik Boernke ,  Kirsten Deist ,  Marc Stitt Nigel ,  Wolfgang Lein ,  Thomas Ehrhardt ,  Andreas Reindl ,  Ralf-Michael Schmidt ,  Annette Freund

    IPC分类号： C12N9/00 ,  C12N9/10 ,  C12N1/20 ,  C12N15/00 ,  C07H21/04

    CPC分类号： C12N9/1014 ,  C12N15/8274

    摘要： The present invention relates to serine hydroxymethyltransferase (E.C. 2.1.2.1) as novel target for herbicides, and to nucleic acid sequences encoding a polypeptide with the biological activity of a serine hydroxymethyltransferase, which, when not present, bring about growth retardation symptoms and chlorotic leaves, comprising the nucleic acid sequence SEQ ID No:3, and functional equivalents of the abovementioned nucleic acid sequence or the nucleic acid sequence SEQ ID NO:7 and functional equivalents of the abovementioned nucleic acid sequence. Moreover, the present invention relates to the use of the abovementioned nucleic acid sequences, of functional analogs of the SEQ ID NO:3 or SEQ ID NO:7 or of polypeptides encoded by one of the abovementioned nucleic acid sequences in a method for identifying herbicidally active compounds which inhibit serine hydroxymethyltransferases, and to the use of these compounds which have been identified by the method as herbicides.

    摘要翻译： 本发明涉及丝氨酸羟甲基转移酶（EC 2.1.2.1）作为除草剂的新靶标，以及编码具有丝氨酸羟甲基转移酶生物活性的多肽的核酸序列，当不存在时，其产生生长迟缓症状和褪绿叶 包括核酸序列SEQ ID No：3和上述核酸序列或核酸序列SEQ ID NO：7的功能等同物和上述核酸序列的功能等同物。 此外，本发明涉及上述核酸序列，SEQ ID NO：3或SEQ ID NO：7的功能类似物或由上述核酸序列之一编码的多肽在除草方法中的用途 抑制丝氨酸羟甲基转移酶的活性化合物，以及通过该方法鉴定的这些化合物作为除草剂的用途。

    Serine hydroxymethyltransferase as a target for herbicides
    7.
    发明授权
    Serine hydroxymethyltransferase as a target for herbicides 失效
    丝氨酸羟甲基转移酶作为除草剂的靶标

    公开(公告)号：US07319013B2

    公开(公告)日：2008-01-15

    申请号：US10507989

    申请日：2003-03-13

    申请人： Uwe Sonnewald ,  Frederik Börnke ,  Kirsten Deist ,  Marc Stitt Nigel ,  Wolfgang Lein ,  Thomas Ehrhardt ,  Andreas Reindl ,  Ralf-Michael Schmidt ,  Annette Freund

    发明人： Uwe Sonnewald ,  Frederik Börnke ,  Kirsten Deist ,  Marc Stitt Nigel ,  Wolfgang Lein ,  Thomas Ehrhardt ,  Andreas Reindl ,  Ralf-Michael Schmidt ,  Annette Freund

    IPC分类号： C12Q1/48 ,  C12N9/10 ,  C12N5/04 ,  C12N5/14 ,  C07H21/04

    CPC分类号： C12N9/1014 ,  C12N15/8274

    摘要： The present invention relates to serine hydroxymethyltransferase (E.C. 2.1.2.1) as novel target for herbicides, and to nucleic acid sequences encoding a polypeptide with the biological activity of a serine hydroxymethyltransferase, which, when not present, bring about growth retardation symptoms and chlorotic leaves, comprising the nucleic acid sequence SEQ ID No:3, and functional equivalents of the abovementioned nucleic acid sequence or the nucleic acid sequence SEQ ID NO:7 and functional equivalents of the abovementioned nucleic acid sequence. Moreover, the present invention relates to the use of the abovementioned nucleic acid sequences, of functional analogs of the SEQ ID NO:3 or SEQ ID NO:7 or of polypeptides encoded by one of the abovementioned nucleic acid sequences in a method for identifying herbicidally active compounds which inhibit serine hydroxymethyltransferases, and to the use of these compounds which have been identified by the method as herbicides.

    摘要翻译： 本发明涉及丝氨酸羟甲基转移酶（EC 2.1.2.1）作为除草剂的新靶标，以及编码具有丝氨酸羟甲基转移酶生物活性的多肽的核酸序列，当不存在时，其产生生长迟缓症状和褪绿叶 包括核酸序列SEQ ID No：3和上述核酸序列或核酸序列SEQ ID NO：7的功能等同物和上述核酸序列的功能等同物。 此外，本发明涉及上述核酸序列，SEQ ID NO：3或SEQ ID NO：7的功能类似物或由上述核酸序列之一编码的多肽在除草方法中的用途 抑制丝氨酸羟甲基转移酶的活性化合物，以及通过该方法鉴定的这些化合物作为除草剂的用途。

    Saccarose-6-phosphate phosphatase as a target for herbicides
    9.
    发明申请
    Saccarose-6-phosphate phosphatase as a target for herbicides 失效
    Saccarose-6-磷酸磷酸酶作为除草剂的靶标

    公开(公告)号：US20060035786A1

    公开(公告)日：2006-02-16

    申请号：US10522096

    申请日：2003-07-16

    申请人： Thomas Ehrhardt ,  Uwe Sonnewald ,  Frederik Bornke ,  Shuai Chen

    发明人： Thomas Ehrhardt ,  Uwe Sonnewald ,  Frederik Bornke ,  Shuai Chen

    IPC分类号： A01N25/00 ,  C12Q1/68 ,  C12Q1/42 ,  C12P21/06 ,  C12N9/16 ,  C40B30/04

    CPC分类号： C12N9/16 ,  C12N15/8274

    摘要： The present invention relates to the use of a polypeptide with the biological activity of a sucrose-6-phosphate phosphatase which, if not present, brings about growth retardation symptoms and chlorotic leaves and which is encoded by the nucleic acid sequences SEQ ID NO:1, SEQ ID NO:3, SEQ ID NO:5 or by a functional equivalent of SEQ ID NO:1, SEQ ID NO:3 or SEQ ID NO:5 as target for herbicides. Moreover, the present invention relates to the use of the abovementioned polypeptides in a method for identifying herbicidal or growth-regulatory compounds which inhibit sucrose-6-phosphate phosphatase. Moreover, the invention relates to the use of these compounds which have been identified via the method as herbicides or growth regulators.

    摘要翻译： 本发明涉及具有蔗糖-6-磷酸磷酸酶的生物学活性的多肽的用途，如果不存在，则会导致生长迟缓症状和褪绿叶，并由核酸序列SEQ ID NO：1编码 ，SEQ ID NO：3，SEQ ID NO：5或功能等同物为SEQ ID NO：1，SEQ ID NO：3或SEQ ID NO：5作为除草剂的靶标。 此外，本发明涉及上述多肽在鉴定抑制蔗糖-6-磷酸磷酸酶的除草或生长调节化合物的方法中的用途。 此外，本发明涉及通过该方法鉴定的这些化合物作为除草剂或生长调节剂的用途。

    Method for the production of transgenic plants with increased virus resistance by silencing vegetable DnaJ-like proteins
    10.
    发明申请
    Method for the production of transgenic plants with increased virus resistance by silencing vegetable DnaJ-like proteins 审中-公开
    通过沉默植物DnaJ样蛋白质生产具有增加的病毒抗性的转基因植物的方法

    公开(公告)号：US20050251879A1

    公开(公告)日：2005-11-10

    申请号：US11039722

    申请日：2005-01-19

    申请人： Daniel Hofius ,  Frederik Bornke ,  Uwe Sonnewald

    发明人： Daniel Hofius ,  Frederik Bornke ,  Uwe Sonnewald

    IPC分类号： C12N15/82 ,  A01H1/00

    CPC分类号： C12N15/8218 ,  C12N15/8283

    摘要： The invention relates to plants and plant cells which have a transient or permanent virus resistance as a result of modulation of the gene expression and/or binding behavior of vegetable DnaJ-like proteins. The invention also relates to methods for the production of transgenic plants with increased virus resistance, wherein the expression of vegetable DnaJ-like proteins which interact with viral components is substantially prevented by silencing the DnaJ-like proteins. The invention further relates to methods for the production of transgenic plants with increased virus resistance, wherein the interaction of viral components with vegetable DnaJ-like proteins is substantially prevented by expression of dominant-negative mutants of the DnaJ-like proteins, by antibodies against DnaJ-like proteins or by specific inhibitors.

    摘要翻译： 本发明涉及由于调节植物DnaJ样蛋白质的基因表达和/或结合行为而具有瞬时或永久性病毒抗性的植物和植物细胞。 本发明还涉及生产具有增加的病毒抗性的转基因植物的方法，其中通过沉默DnaJ样蛋白质基本上防止了与病毒组分相互作用的植物DnaJ样蛋白的表达。 本发明还涉及用于生产具有增加的病毒抗性的转基因植物的方法，其中病毒组分与植物DnaJ样蛋白的相互作用通过DnaJ抗体的表达来显着地抑制DnaJ样蛋白的显性负性突变体 类蛋白或特异性抑制剂。